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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BP334921 is the fusion of parental proteins OSBPL1A, HTN3 (from a repository: Tue Feb 28 03:13:35 2017)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)2
The number (and %) of the onco-proteins1 (50.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)1 (100.00 %)
The number (and %) of affected PPIs1 (100.00 %)
The number of possible different fusions1
PPI diameter1
PPI radius1
The average degree of PPI1.000
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients2 (100.00 %)
The number (and %) of a zero Betweenness Centrality2 (100.00 %)


List of the fusions

PPI for parental proteins: HTN3,OSBPL1A All fusions
: BP334921;
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 BP334921chimera100Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein
2 VAPBinteractor100ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit
ZapB (PF06005, IPR009252): Cell division protein ZapB
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 BCL6oncoproteinBTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
DZR (PF12773, IPR025874): Double zinc ribbon
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
2 BIN3interactorBAR (PF03114, IPR004148, SM00721): BAR domain
3 CARNMT1interactorN2227 (PF07942, IPR012901): N2227-like protein
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
4 HEXIM1oncoproteinAPG6 (PF04111, IPR007243): Autophagy protein Apg6
DivIC (PF04977, IPR007060): Septum formation initiator
Shugoshin_N (PF07558, IPR011516): Shugoshin N-terminal coiled-coil region
HEXIM (PF15313, IPR024872): Hexamethylene bis-acetamide-inducible protein
5 HSPA8oncoproteinHSP70 (PF00012, IPR013126): Hsp70 protein
6 HTN3parental proteinAJAP1_PANP_C (PF15298, IPR029198): AJAP1/PANP C-terminus
7 KIFAP3interactorKAP (PF05804): Kinesin-associated protein (KAP)
8 NPM1suppressorNucleoplasmin (PF03066): Nucleoplasmin
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
9 OSBPL1Aparental proteinDinB (PF05163, IPR007837): DinB family
Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
PH_11 (PF15413): Pleckstrin homology domain
10 POLG2interactorHGTP_anticodon (PF03129, IPR004154): Anticodon binding domain

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