1 |
BP232903 | chimera | 49 | 0.158 | 1352.099 | Tropomyosin (PF00261, IPR000533): Tropomyosin |
2 |
ACTA1 | interactor | 8 | 0.750 | 2.782 | Actin (PF00022, IPR004000, SM00268): Actin |
3 |
ACTN1 | protein found in more fusions | 15 | 0.813 | 4.494 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Dak2 (PF02734, IPR004007, SM01120): DAK2 domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair Uds1 (PF15456, IPR029191): Up-regulated During Septation |
4 |
ACTN2 | protein found in more fusions | 10 | 0.528 | 15.333 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Nsp1_C (PF05064, IPR007758): Nsp1-like C-terminal region Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
5 |
ACTN4 | interactor | 16 | 0.825 | 5.816 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair Uds1 (PF15456, IPR029191): Up-regulated During Septation |
6 |
ADD1 | interactor | 5 | 1.000 | 0 | Aldolase_II (PF00596, IPR001303, SM01007): Class II Aldolase and Adducin N-terminal domain CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal |
7 |
AHCYL1 | suppressor | 6 | 0.600 | 3.500 | AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF515 (PF04415, IPR007509): Protein of unknown function (DUF515) Big_3_5 (PF16640, IPR032109): Bacterial Ig-like domain (group 3) |
8 |
AKT1 | oncoprotein | 7 | 0.667 | 1.905 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
9 |
ANLN | oncoprotein | 14 | 0.879 | 2.162 | Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus |
10 |
ATP5F1 | interactor | 5 | 1.000 | 0 | Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2105 (PF09878, IPR019212): Predicted membrane protein (DUF2105) |
11 |
BCAP31 | protein found in more fusions | 5 | 0.500 | 1.200 | Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) |
12 |
CAPZA2 | interactor | 19 | 0.673 | 20.706 | F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit |
13 |
CCAR1 | oncoprotein | 1 | 0 | 0 | Cucumo_2B (PF03263, IPR004946): Cucumovirus protein 2B DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) IncA (PF04156, IPR007285): IncA protein Presenilin (PF01080, IPR001108): Presenilin SAP (PF02037, IPR003034, SM00513): SAP domain FimP (PF09766, IPR019163): Fms-interacting protein DBC1 (PF14443, IPR025954, SM01122): DBC1 DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) S1-like (PF14444, IPR025223): S1-like DUF4481 (PF14800, IPR028054): Domain of unknown function (DUF4481) FAM176 (PF14851): FAM176 family |
14 |
CDK2 | oncoprotein | 18 | 0.493 | 40.533 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
15 |
CKMT1A | interactor | 2 | 1.000 | 0 | ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain |
16 |
CKMT1B | interactor | 2 | 1.000 | 0 | ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain |
17 |
CORO1B | interactor | 10 | 0.978 | 0.143 | DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_4 (PF16300): Type of WD40 repeat |
18 |
COX4I1 | interactor | 6 | 0.600 | 3.833 | COX4 (PF02936, IPR004203): Cytochrome c oxidase subunit IV |
19 |
CPSF7 | interactor | 1 | 0 | 0 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
20 |
DDX3X | suppressor | 4 | 0.833 | 0.286 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
21 |
DSTN | interactor | 6 | 1.000 | 0 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
22 |
DYNC1H1 | interactor | 4 | 0.667 | 0.800 | AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5 |
23 |
FLNA | suppressor | 16 | 0.742 | 14.224 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat |
24 |
IQGAP1 | interactor | 19 | 0.649 | 22.410 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain |
25 |
LRRK2 | oncoprotein | 8 | 0.619 | 4.467 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043) T2SSE (PF00437, IPR001482): Type II/IV secretion system protein Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) PQQ_2 (PF13360, IPR002372): PQQ-like domain LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
26 |
MAGEA10 | interactor | 1 | 0 | 0 | MAGE (PF01454, IPR002190): MAGE family SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
27 |
MYH3 | interactor | 2 | 1.000 | 0 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
28 |
MYH6 | interactor | 3 | 1.000 | 0 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
29 |
MYH7 | interactor | 3 | 0.667 | 0.667 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
30 |
MYH9 | oncoprotein | 22 | 0.563 | 55.632 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
31 |
MYO18A | interactor | 17 | 0.743 | 11.380 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_tail_1 (PF01576, IPR002928): Myosin tail PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
32 |
MYO19 | interactor | 15 | 0.886 | 2.305 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
33 |
MYO5C | interactor | 13 | 0.885 | 1.805 | DIL (PF01843, IPR018444, SM01132): DIL domain DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Pilus_CpaD (PF09476, IPR019027): Pilus biogenesis CpaD protein (pilus_cpaD) Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) YtxH (PF12732, IPR024623): YtxH-like protein Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
34 |
NDUFB10 | interactor | 5 | 0.700 | 1.500 | NDUFB10 (PF10249, IPR019377): NADH-ubiquinone oxidoreductase subunit 10 |
35 |
NEB | oncoprotein | 3 | 1.000 | 0 | Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat Shal-type (PF11601, IPR021645): Shal-type voltage-gated potassium channels, N-terminal DUF3410 (PF11890, IPR024531): Domain of unknown function (DUF3410) DUF3417 (PF11897, IPR024517): Protein of unknown function (DUF3417) G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site NFRKB_winged (PF14465, IPR025220): NFRKB Winged Helix-like SH3_9 (PF14604, IPR001452): Variant SH3 domain |
36 |
PDLIM7 | interactor | 11 | 0.909 | 0.843 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
37 |
PPP1CB | interactor | 21 | 0.567 | 52.099 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
38 |
RBPJ | interactor | 3 | 0.667 | 0.667 | BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding TIG (PF01833, IPR002909): IPT/TIG domain |
39 |
SF3B2 | interactor | 2 | 1.000 | 0 | DUF382 (PF04037, IPR007180): Domain of unknown function (DUF382) PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region PSP (PF04046, IPR006568, SM00581): PSP SAP (PF02037, IPR003034, SM00513): SAP domain Usp (PF00582, IPR006016): Universal stress protein family Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 Vma12 (PF11712, IPR021013): Endoplasmic reticulum-based factor for assembly of V-ATPase FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
40 |
SLC4A1AP | interactor | 1 | 0 | 0 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif FHA (PF00498, IPR000253, SM00240): FHA domain PKI (PF02827, IPR004171): cAMP-dependent protein kinase inhibitor FAM177 (PF14774, IPR028260): FAM177 family PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
41 |
SP1 | protein found in more fusions | 9 | 0.679 | 5.667 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
42 |
SRXN1 | interactor | 4 | 0.833 | 0.500 | ParBc (PF02195, IPR003115): ParB-like nuclease domain |
43 |
SSB | interactor | 3 | 1.000 | 0 | HMA (PF00403, IPR006121): Heavy-metal-associated domain La (PF05383, IPR006630, SM00715): La domain Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 (PF08777, IPR014886): RNA binding motif |
44 |
STAM | interactor | 2 | 1.000 | 0 | GAT (PF03127, IPR004152): GAT domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
45 |
TAF15 | oncoprotein | 2 | 1.000 | 0 | API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) GRP (PF07172, IPR010800): Glycine rich protein family Presenilin (PF01080, IPR001108): Presenilin RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others |
46 |
TPM1 | protein found in more fusions | 28 | 0.362 | 154.056 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
47 |
TPM3 | oncoprotein | 27 | 0.382 | 131.299 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
48 |
TPM4 | oncoprotein | 23 | 0.478 | 64.889 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
49 |
UQCRC2 | oncoprotein | 3 | 1.000 | 0 | Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain |
50 |
ZNF250 | interactor | 2 | 0 | 0 | KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |