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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: BM827819 is the fusion of parental proteins WDR12, VPS52 (from a repository: Tue Jul 10 10:34:31 2018)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)69
The number (and %) of the onco-proteins11 (15.94 %)
The number (and %) of the tumor suppressors4 (5.80 %)
Total number of binary PPIs (saturation %)162 (6.91 %)
The number (and %) of affected PPIs68 (41.98 %)
The number of possible different fusions6
PPI diameter2
PPI radius1
The average degree of PPI4.203
Assortativity coefficient-0.3619
The network average Clustering coefficient0.572
The number (and %) of a zero Clustering coefficients18 (26.09 %)
The number (and %) of a zero Betweenness Centrality42 (60.87 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: VPS52,WDR12 All fusions
: BM827819;
Proteins found in more fusions TRAF6 (see 1 fusions); TXLNA (see 3 fusions); TPM3 (see 2 fusions); GRK5 (see 4 fusions); NTRK1/TPM3 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BM827819chimera680.0344067.667Vps52 (PF04129, IPR007258): Vps52 / Sac2 family
COG5 (PF10392, IPR019465): Golgi transport complex subunit 5
Sec3_C (PF09763, IPR019160): Exocyst complex component Sec3
2 AAMPinteractor21.0000PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
3 ARNT2interactor21.0000HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily
4 ATP6V1Dinteractor100ATP-synt_D (PF01813, IPR002699): ATP synthase subunit D
5 BSGinteractor50.9000.500Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
6 C1orf109interactor40.5002.500CK2S (PF15011, IPR029159): Casein Kinase 2 substrate
7 C4BPBinteractor100Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
8 CACNA1Ainteractor100Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain
GRP (PF07172, IPR010800): Glycine rich protein family
Ion_trans (PF00520, IPR005821): Ion transport protein
Roughex (PF06020, IPR009259): Drosophila roughex protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
9 CCDC146interactor21.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex
Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
10 CCDC33interactor40.5003.000C2 (PF00168, IPR000008, SM00239): C2 domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
SlyX (PF04102, IPR007236): SlyX
11 DDX27interactor21.0000Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
12 DDX6oncoprotein31.0000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
13 EPM2AIP1interactor31.0000Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
14 FAF2interactor200DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
UBX (PF00789, IPR001012, SM00166): UBX domain
Thioredoxin_7 (PF13899): Thioredoxin-like
UBA_4 (PF14555): UBA-like domain
15 FAM184Ainteractor100APG6 (PF04111, IPR007243): Autophagy protein Apg6
Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
DivIC (PF04977, IPR007060): Septum formation initiator
DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
SlyX (PF04102, IPR007236): SlyX
ApoO (PF09769, IPR019166): Apolipoprotein O
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
FAM184 (PF15665): Family with sequence similarity 184, A and B
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
16 GFM2interactor100EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
17 GOLGA1interactor100GRIP (PF01465, IPR000237, SM00755): GRIP domain
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
18 GRK5protein found in more fusions40.6670.500Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
19 HAUS1interactor40.6670.500THP2 (PF09432, IPR018557): Tho complex subunit THP2
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
20 HEATR1interactor30.6671.000BP28CT (PF08146, IPR012954, SM01036): BP28CT (NUC211) domain
HEAT (PF02985, IPR000357): HEAT repeat
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
CLASP_N (PF12348, IPR024395): CLASP N terminal
U3snoRNP10 (PF12397, IPR022125): U3 small nucleolar RNA-associated protein 10
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
HEAT_EZ (PF13513): HEAT-like repeat
21 KANK2interactor80.38112.000KN_motif (PF12075, IPR021939): KN motif
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain
G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
22 KIAA1217interactor21.0000AIP3 (PF03915, IPR022782, SM00806): Actin interacting protein 3
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
MRI (PF15325, IPR028278): Modulator of retrovirus infection
23 KIF5Binteractor30.6671.000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3
DUF4226 (PF10774, IPR019710): Domain of unknown function (DUF4226)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
24 KLC3interactor40.6671.000TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
TPR_12 (PF13424): Tetratricopeptide repeat
25 KMT2Einteractor21.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124)
PHD_3 (PF13922, IPR026905): PHD domain of transcriptional enhancer, Asx
DUF4666 (PF15697, IPR031421): Domain of unknown function (DUF4666)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
26 LMO4interactor21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger
27 MAPK3oncoprotein200Pkinase (PF00069, IPR000719): Protein kinase domain
28 METTL13interactor21.0000Methyltransf_11 (PF08241, IPR013216): Methyltransferase domain
Spermine_synth (PF01564, IPR001045): Spermine/spermidine synthase
Methyltransf_23 (PF13489): Methyltransferase domain
29 MFAP1interactor40.6671.500MFAP1 (PF06991, IPR009730): Microfibril-associated/Pre-mRNA processing
DUF3464 (PF11947, IPR021855): Protein of unknown function (DUF3464)
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
30 MRPL11interactor21.0000Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain
Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain
31 NFKBIBinteractor21.0000Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
32 NOP2interactor21.0000BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II)
Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F
P120R (PF08062, IPR012586): P120R (NUC006) repeat
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477)
FAM176 (PF14851): FAM176 family
Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF
33 NTRK1oncoprotein220.138176.167I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
34 PPP1R18interactor21.0000Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124)
Phostensin (PF13914, IPR025907): Phostensin PP1-binding and SH3-binding region
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
35 PRKAA1suppressor50.4005.167Pkinase (PF00069, IPR000719): Protein kinase domain
AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
36 PRKAA2suppressor21.0000Pkinase (PF00069, IPR000719): Protein kinase domain
AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
37 RAB4Aoncoprotein21.0000Ras (PF00071, IPR001806, SM00173): Ras family
38 RABEP2interactor30.6671.000Rab5-bind (PF09311, IPR015390): Rabaptin-like protein
Rabaptin (PF03528, IPR018514): Rabaptin
39 RNF41interactor31.0000Sina (PF03145, IPR018121): Seven in absentia protein family
USP8_interact (PF08941, IPR015036): USP8 interacting
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
40 SH2D4Ainteractor21.0000Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
SH2 (PF00017, IPR000980, SM00252): SH2 domain
DUF2039 (PF10217, IPR019351): Uncharacterized conserved protein (DUF2039)
41 SLAMF1interactor31.0000ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
SLAM (PF06214, IPR010407): Signaling lymphocytic activation molecule (SLAM) protein
42 STX11interactor90.25020.000KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Syntaxin (PF00804, IPR006011, SM00503): Syntaxin
SNARE (PF05739, IPR000727, SM00397): SNARE domain
43 STX6interactor50.8001.333Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
SNARE (PF05739, IPR000727, SM00397): SNARE domain
44 TBC1D13interactor100RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
45 TBC1D22Binteractor100RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
DUF4502 (PF14950, IPR028026): Domain of unknown function (DUF4502)
46 TCEANCinteractor100Ribosomal_L37e (PF01907, IPR001569): Ribosomal protein L37e
Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
47 TEAD4interactor100TEA (PF01285, IPR000818, SM00426): TEA/ATTS domain family
48 THAP11interactor200THAP (PF05485, IPR006612, SM00980): THAP domain
DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722)
MRP-S31 (PF15433, IPR026299): Mitochondrial 28S ribosomal protein S31
FAM76 (PF16046, IPR032017): FAM76 protein
49 TPM3oncoprotein40.6671.000Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
50 TRAF6protein found in more fusions50.5002.667SlyX (PF04102, IPR007236): SlyX
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
51 TSSC1suppressor51.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
52 TSSK3interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
53 TSTD2interactor21.0000Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
Rhodanese_C (PF12368, IPR022111): Rhodanase C-terminal
zf-C2H2_4 (PF13894): C2H2-type zinc finger
54 TUFMinteractor50.5004.333GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
55 TXLNAprotein found in more fusions41.0000Taxilin (PF09728, IPR026183): Myosin-like coiled-coil protein
KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase
56 TXN2interactor100Thioredoxin (PF00085, IPR013766): Thioredoxin
57 USP14interactor40.8330.500UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
58 USP2interactor30.6670.667UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
59 VAMP4interactor31.0000Synaptobrevin (PF00957, IPR001388): Synaptobrevin
60 VPS28interactor31.0000VPS28 (PF03997, IPR007143): VPS28 protein
61 VPS37Binteractor50.6003.000Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
62 VPS50interactor70.7622.833Vps54_N (PF10475, IPR019515): Vacuolar-sorting protein 54, of GARP complex
DUF2451 (PF10474, IPR019514): Protein of unknown function C-terminus (DUF2451)
63 VPS51interactor80.6795.500DUF1736 (PF08409, IPR013618): Domain of unknown function (DUF1736)
Vps51 (PF08700): Vps51/Vps67
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
Sec5 (PF15469): Exocyst complex component Sec5
64 VPS53suppressor90.6437.000Vps53_N (PF04100, IPR007234): Vps53-like, N-terminal
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
DUF2451 (PF10474, IPR019514): Protein of unknown function C-terminus (DUF2451)
VPS53_C (PF16854, IPR031745): Vacuolar protein sorting-associated protein 53 C-terminus
65 VPS54interactor60.8671.000Vps54 (PF07928, IPR012501): Vps54-like protein
Vps54_N (PF10475, IPR019515): Vacuolar-sorting protein 54, of GARP complex
SBP_bac_6 (PF13343): Bacterial extracellular solute-binding protein
YqzH (PF14164, IPR025546): YqzH-like protein
66 VRK1oncoprotein200Pkinase (PF00069, IPR000719): Protein kinase domain
67 WTAPoncoprotein100DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
SOSSC (PF15925, IPR031821): SOSS complex subunit C
Wtap (PF17098, IPR029732): WTAP/Mum2p family
68 XPO1interactor150.20078.667CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
69 ZMAT2interactor100Cgr1 (PF03879, IPR005579): Cgr1 family
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ACBD3interactorACBP (PF00887, IPR000582): Acyl CoA binding protein
CDC45 (PF02724, IPR003874): CDC45-like protein
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking
NINJA_B (PF16136, IPR032310): Putative nuclear localisation signal
2 BMI1oncoproteinzf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
3 BOP1oncoproteinBOP1NT (PF08145, IPR012953, SM01035): BOP1NT (NUC169) domain
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF3038 (PF11237, IPR021399): Protein of unknown function (DUF3038)
Frtz (PF11768, IPR024511): WD repeat-containing and planar cell polarity effector protein Fritz
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
4 BRIX1interactorBrix (PF04427, IPR007109, SM00879): Brix domain
5 BTRConcoproteinWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
6 BYSLinteractorBystin (PF05291, IPR007955): Bystin
MEA1 (PF06910, IPR009685): Male enhanced antigen 1 (MEA1)
7 CASQ2interactorCalsequestrin (PF01216, IPR001393): Calsequestrin
SDA1 (PF05285, IPR007949): SDA1
8 CHMP7interactorSnf7 (PF03357, IPR005024): Snf7
9 CSNK2BinteractorCK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
10 DDX19AinteractorDEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
11 DDX24interactorDEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Tti2 (PF10521, IPR018870): Tti2 family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
12 DDX54interactorDBP10CT (PF08147, IPR012541, SM01123): DBP10CT (NUC160) domain
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
13 EBNA1BP2interactorEbp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2
14 FBXW11interactorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
15 FTSJ3interactorDUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
FtsJ (PF01728, IPR002877): FtsJ-like methyltransferase
M16C_assoc (PF08367, IPR013578): Peptidase M16C associated
Orthopox_F8 (PF05886, IPR008726): Orthopoxvirus F8 protein
Spb1_C (PF07780, IPR012920): Spb1 C-terminal domain
DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381)
RRP14 (PF15459, IPR029188): 60S ribosome biogenesis protein Rrp14
16 GTPBP4suppressorDUF258 (PF03193, IPR004881): Protein of unknown function, DUF258
MRC1 (PF09444, IPR018564): MRC1-like domain
NOG1 (PF06858, IPR010674): Nucleolar GTP-binding protein 1 (NOG1)
NOGCT (PF08155, IPR012973): NOGCT (NUC087) domain
Lip_prot_lig_C (PF10437, IPR019491): Bacterial lipoate protein ligase C-terminus
AAA_16 (PF13191): AAA ATPase domain
17 HIST1H1ConcoproteinAmelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin)
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
18 HNRNPDLinteractorCBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
19 IFI16suppressorHIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
20 INPP1interactorInositol_P (PF00459, IPR000760): Inositol monophosphatase family
21 MDN1interactorAAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily)
DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
DnaB_C (PF03796, IPR007694): DnaB-like helicase C terminal domain
AAA_16 (PF13191): AAA ATPase domain
Sigma54_activ_2 (PF14532, IPR002078): Sigma-54 interaction domain
22 MRTO4interactorGlu_syn_central (PF04898, IPR006982): Glutamate synthase central domain
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
23 NIFKinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
hNIFK_binding (PF12196, IPR021043): FHA Ki67 binding domain of hNIFK
24 NOC3LinteractorCBF (PF03914, IPR005612, SM00521): CBF/Mak21 family
Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
DsrD (PF08679, IPR014793): Dissimilatory sulfite reductase D (DsrD)
GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family
NOC3p (PF07540, IPR011501): Nucleolar complex-associated protein
Scm3 (PF10384, IPR018465): Centromere protein Scm3
25 PES1interactorPescadillo_N (PF06732, IPR010613): Pescadillo N-terminus
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
DUF3347 (PF11827, IPR021782): Protein of unknown function (DUF3347)
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
26 PPP2CBsuppressorMetallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
27 PPP3CBinteractorCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
PRIMA1 (PF16101): Proline-rich membrane anchor 1
28 PSPC1interactorFUSC (PF04632, IPR006726): Fusaric acid resistance protein family
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Zot (PF05707, IPR008900): Zonular occludens toxin (Zot)
29 PUS1interactorPseudoU_synth_1 (PF01416, IPR020097): tRNA pseudouridine synthase
30 RNF2interactorzf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
31 RPL36interactorRibosomal_L36e (PF01158, IPR000509): Ribosomal protein L36e
32 RPL4interactorRibosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
33 RPL7interactorRibosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
34 RPUSD2interactorPseudoU_synth_2 (PF00849, IPR006145): RNA pseudouridylate synthase
35 RTCBinteractorRtcB (PF01139, IPR001233): tRNA-splicing ligase RtcB
36 SEPHS1interactorAIRS (PF00586, IPR000728): AIR synthase related protein, N-terminal domain
AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain
37 SIRT7interactorDUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
38 SNF8interactorEAP30 (PF04157, IPR007286): EAP30/Vps36 family
39 SRSF5interactorDUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
40 SUGT1interactorCheC (PF04509, IPR007597): CheC-like family
CS (PF04969, IPR007052): CS domain
SGS (PF05002, IPR007699): SGS domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
41 TBCDinteractorHEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal
HEAT_EZ (PF13513): HEAT-like repeat
42 TOM1oncoproteinGAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain
43 TOMM34interactorTPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
SHNi-TPR (PF10516, IPR019544): SHNi-TPR
TPR_12 (PF13424): Tetratricopeptide repeat
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
DUF4919 (PF16266, IPR032578): Domain of unknown function (DUF4919)
44 TSG101suppressorAPG6 (PF04111, IPR007243): Autophagy protein Apg6
Laminin_II (PF06009, IPR010307): Laminin Domain II
UEV (PF05743, IPR008883): UEV domain
Vps23_core (PF09454, IPR017916): Vps23 core domain
45 TSNinteractorTranslin (PF01997, IPR002848): Translin family
46 UBE2ZinteractorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
47 VAT1interactorADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain
ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
48 VPS25interactorESCRT-II (PF05871, IPR008570): ESCRT-II complex subunit
49 VPS29interactorMetallophos_2 (PF12850, IPR024654): Calcineurin-like phosphoesterase superfamily domain
50 VPS36interactorEAP30 (PF04157, IPR007286): EAP30/Vps36 family
Vps36_ESCRT-II (PF11605, IPR021648): Vacuolar protein sorting protein 36 Vps36
51 VPS52parental proteinVps52 (PF04129, IPR007258): Vps52 / Sac2 family
COG5 (PF10392, IPR019465): Golgi transport complex subunit 5
Sec3_C (PF09763, IPR019160): Exocyst complex component Sec3
52 WDR12parental proteinNLE (PF08154, IPR012972): NLE (NUC135) domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
53 WDR5interactorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
54 WDR92interactorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Itfg2 (PF15907, IPR031793): Integrin-alpha FG-GAP repeat-containing protein 2

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