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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: BM750642 is the fusion of parental proteins DGUOK, PRKD2 (from a repository: Mon Feb 27 08:00:02 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)36
The number (and %) of the onco-proteins13 (36.11 %)
The number (and %) of the tumor suppressors1 (2.78 %)
Total number of binary PPIs (saturation %)74 (11.75 %)
The number (and %) of affected PPIs35 (47.30 %)
The number of possible different fusions9
PPI diameter2
PPI radius1
The average degree of PPI3.556
Assortativity coefficient-0.3688
The network average Clustering coefficient0.486
The number (and %) of a zero Clustering coefficients13 (36.11 %)
The number (and %) of a zero Betweenness Centrality25 (69.44 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: DGUOK,PRKD2 All fusions
: BM750642;
Proteins found in more fusions GORASP1 (see 1 fusions); RXRA (see 2 fusions); HDAC7 (see 1 fusions); RFFL (see 1 fusions); HSP90AA1 (see 2 fusions); HDAC5 (see 1 fusions); APP (see 4 fusions); GRIP1 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BM750642chimera350.0491054.333ABC1 (PF03109, IPR004147): ABC1 family
Pkinase (PF00069, IPR000719): Protein kinase domain
2 APPprotein found in more fusions50.6671.500APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
3 CALB2interactor100EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
RecG_N (PF17190): RecG N-terminal helical domain
4 CAMKVinteractor31.0000Pkinase (PF00069, IPR000719): Protein kinase domain
5 CASKinteractor21.0000L27 (PF02828, IPR014775, SM00569): L27 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase (PF00069, IPR000719): Protein kinase domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
6 CDK10interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
7 DSToncoprotein100CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ZYG-11_interact (PF05884, IPR008574): Interactor of ZYG-11
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain
Laminin_II (PF06009, IPR010307): Laminin Domain II
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
Phasin (PF05597, IPR008769): Poly(hydroxyalcanoate) granule associated protein (phasin)
Spectrin (PF00435, IPR002017): Spectrin repeat
Nbl1_Borealin_N (PF10444, IPR018851): Nbl1 / Borealin N terminal
XhlA (PF10779, IPR019715): Haemolysin XhlA
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
FTA4 (PF13093, IPR025207): Kinetochore complex Fta4 of Sim4 subunit, or CENP-50
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
NYD-SP28 (PF14772): Sperm tail
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
8 ELAVL4interactor21.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
9 GLRX3interactor31.0000Glutaredoxin (PF00462, IPR002109): Glutaredoxin
Thioredoxin (PF00085, IPR013766): Thioredoxin
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
10 GORASP1protein found in more fusions31.0000GRASP55_65 (PF04495, IPR024958): GRASP55/65 PDZ-like domain
11 GRIP1protein found in more fusions31.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
12 HDAC5protein found in more fusions70.4677.000Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
13 HDAC7protein found in more fusions41.0000Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO
14 HEY1oncoprotein100Hairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
HTH_Crp_2 (PF13545, IPR012318): Crp-like helix-turn-helix domain
15 HSP90AA1oncoprotein70.5335.833HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
16 IFNAR1oncoprotein100Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III
Tissue_fac (PF01108, IPR003961): Tissue factor
17 MTF2interactor100PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Mtf2_C (PF14061, IPR025894): Polycomb-like MTF2 factor 2
DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537)
18 NCAM1interactor21.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Syndecan (PF01034, IPR027789): Syndecan domain
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
19 NGDNinteractor100Sas10_Utp3 (PF04000, IPR007146): Sas10/Utp3/C1D family
FAM176 (PF14851): FAM176 family
TMEM247 (PF15444, IPR029200): Transmembrane protein 247
20 NGRNinteractor100Neugrin (PF06413, IPR010487): Neugrin
21 NTRK1oncoprotein120.23640.167I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
22 PDLIM7interactor21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
23 PFDN1interactor100Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
24 PHYHIPinteractor100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
25 PRKD3interactor30.6670.667PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
26 PSG3interactor100V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
27 RAE1interactor30.6670.667Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
28 RARBsuppressor21.0000zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
29 RFFLprotein found in more fusions200FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Armet (PF10208, IPR019345): Degradation arginine-rich protein for mis-folding
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
30 RRBP1interactor21.0000Fez1 (PF06818): Fez1
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Pentapeptide_2 (PF01469, IPR002989): Pentapeptide repeats (8 copies)
Rib_recp_KP_reg (PF05104, IPR007794): Ribosome receptor lysine/proline rich region
RTBV_P46 (PF06216, IPR009347): Rice tungro bacilliform virus P46 protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
UPF0767 (PF15990, IPR031933): UPF0767 family
31 RXRAoncoprotein40.6671.000zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1
32 SEC23IPinteractor31.0000DDHD (PF02862, IPR004177, SM01127): DDHD domain
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
WWE (PF02825, IPR004170, SM00678): WWE domain
33 SNRNP70interactor40.6671.333RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
34 TSC22D4interactor100AflR (PF08493, IPR013700): Aflatoxin regulatory protein
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
35 XPO1interactor80.39315.333CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
36 YWHAQinteractor50.5004.16714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 AMPHoncoproteinBAR (PF03114, IPR004148, SM00721): BAR domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
PBP_N (PF17093, IPR031375): Penicillin-binding protein N-terminus
2 ANK2interactorDeath (PF00531, IPR000488, SM00005): Death domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
Bud13 (PF09736, IPR018609): Pre-mRNA-splicing factor of RES complex
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
3 ARL8BinteractorArf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
4 ATP2B2interactorCation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
ATP_Ca_trans_C (PF12424, IPR022141): Plasma membrane calcium transporter ATPase C terminal
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
5 ATP2B3interactorCation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
ATP_Ca_trans_C (PF12424, IPR022141): Plasma membrane calcium transporter ATPase C terminal
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
6 ATP4AinteractorCation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
H-K_ATPase_N (PF09040, IPR015127): Gastric H+/K+-ATPase, N terminal domain
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
7 BIN1suppressorBAR (PF03114, IPR004148, SM00721): BAR domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
8 CAMK2AinteractorCaMKII_AD (PF08332, IPR013543): Calcium/calmodulin dependent protein kinase II association domain
Pkinase (PF00069, IPR000719): Protein kinase domain
9 CAMK2BoncoproteinCaMKII_AD (PF08332, IPR013543): Calcium/calmodulin dependent protein kinase II association domain
Pkinase (PF00069, IPR000719): Protein kinase domain
10 CDH13suppressorCadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cu-binding_MopE (PF11617, IPR021655): Putative metal-binding motif
11 CNTN1interactorfn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Receptor_2B4 (PF11465, IPR024303): Natural killer cell receptor 2B4
Ig_3 (PF13927): Immunoglobulin domain
12 CRMP1interactorAmidohydro_1 (PF01979, IPR006680): Amidohydrolase family
Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family
13 DCKinteractordNK (PF01712, IPR002624): Deoxynucleoside kinase
14 DCLK1interactorDCX (PF03607, IPR003533, SM00537): Doublecortin
Pkinase (PF00069, IPR000719): Protein kinase domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
15 DGUOKparental proteindNK (PF01712, IPR002624): Deoxynucleoside kinase
16 DNM1interactorDynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
PH (PF00169, IPR001849, SM00233): PH domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
17 DNM1LinteractorDynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
AAA_16 (PF13191): AAA ATPase domain
18 DPYSL2interactorAmidohydro_1 (PF01979, IPR006680): Amidohydrolase family
Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family
19 DPYSL3interactorAmidohydro_1 (PF01979, IPR006680): Amidohydrolase family
Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family
20 DPYSL4interactorAmidohydro_1 (PF01979, IPR006680): Amidohydrolase family
Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family
21 DPYSL5interactorAmidohydro_1 (PF01979, IPR006680): Amidohydrolase family
22 EDIL3interactorEGF (PF00008, IPR000742, SM00181): EGF-like domain
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
23 EEF1A2oncoproteinGTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
24 EPB41L1interactor4_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
25 ERC2oncoprotein3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
Cast (PF10174, IPR019323): RIM-binding protein of the cytomatrix active zone
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
26 GNAO1interactorG-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
27 GNAQoncoproteinG-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
28 GNG2interactorG-gamma (PF00631, IPR015898, SM00224): GGL domain
SidE (PF12252, IPR021014): Dot/Icm substrate protein
29 GPM6BinteractorPspB (PF06667, IPR009554): Phage shock protein B
Myelin_PLP (PF01275, IPR001614, SM00002): Myelin proteolipid protein (PLP or lipophilin)
30 GRIA2interactorANF_receptor (PF01094, IPR001828): Receptor family ligand binding region
Lig_chan (PF00060, IPR001320): Ligand-gated ion channel
Lig_chan-Glu_bd (PF10613, IPR019594, SM00918): Ligated ion channel L-glutamate- and glycine-binding site
31 HIST1H1BoncoproteinPneumo_att_G (PF05539, IPR008781): Pneumovirinae attachment membrane glycoprotein G
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
32 HIST1H2BLinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
33 HPCAinteractorEF-hand_7 (PF13499, IPR011992): EF-hand domain pair
34 HPCAL1interactorDUF2554 (PF10829, IPR020117): Protein of unknown function (DUF2554)
35 HPCAL4interactorEF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
36 L1CAMoncoproteinfn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
EVC2_like (PF12297, IPR022076): Ellis van Creveld protein 2 like protein
Bravo_FIGEY (PF13882, IPR026966): Bravo-like intracellular region
Ig_3 (PF13927): Immunoglobulin domain
37 LIG4interactorAPG17 (PF04108, IPR007240): Autophagy protein Apg17
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region
DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain
DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus
DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
38 MAP2oncoproteinMAP2_projctn (PF08377, IPR013588): MAP2/Tau projection domain
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
RII_binding_1 (PF10522, IPR018459): RII binding domain
CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated
39 MAP2K1oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
DUF3216 (PF11505, IPR023108): Protein of unknown function (DUF3216)
40 MAPTinteractorTubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
41 NAPBinteractorSNAP (PF14938): Soluble NSF attachment protein, SNAP
42 NCALDinteractorEF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
43 NTMinteractorI-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set_CD47 (PF08204, IPR013270): CD47 immunoglobulin-like domain
Ig_3 (PF13927): Immunoglobulin domain
44 PRKD2parental proteinABC1 (PF03109, IPR004147): ABC1 family
Pkinase (PF00069, IPR000719): Protein kinase domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
45 PXNoncoproteinLIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
46 RAB14oncoproteinRas (PF00071, IPR001806, SM00173): Ras family
47 RAB3AoncoproteinG-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
Ras (PF00071, IPR001806, SM00173): Ras family
DUF2757 (PF10955, IPR020115): Protein of unknown function (DUF2757)
48 RAB6BoncoproteinRas (PF00071, IPR001806, SM00173): Ras family
49 SLC12A5interactorAA_permease (PF00324, IPR004841): Amino acid permease
SLC12 (PF03522, IPR018491): Solute carrier family 12
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
50 SNAP25interactorSNAP-25 (PF00835, IPR000928): SNAP-25 family
Use1 (PF09753, IPR019150): Membrane fusion protein Use1
51 SNAP91interactorANTH (PF07651, IPR011417): ANTH domain
MGC-24 (PF05283, IPR007947): Multi-glycosylated core protein 24 (MGC-24), sialomucin
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
52 SNCAinteractorSynuclein (PF01387, IPR001058): Synuclein
53 SNCBinteractorSynuclein (PF01387, IPR001058): Synuclein
54 STX1AinteractorSyntaxin (PF00804, IPR006011, SM00503): Syntaxin
SNARE (PF05739, IPR000727, SM00397): SNARE domain
4HB_MCP_1 (PF12729, IPR024478): Four helix bundle sensory module for signal transduction
55 STX1BinteractorSyntaxin (PF00804, IPR006011, SM00503): Syntaxin
SNARE (PF05739, IPR000727, SM00397): SNARE domain
56 STXBP1interactorSec1 (PF00995, IPR001619): Sec1 family
57 SYN1interactorSynapsin_C (PF02750, IPR020898): Synapsin, ATP binding domain
Synapsin_N (PF10581, IPR019736): Synapsin N-terminal
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
Synapsin (PF02078, IPR020897): Synapsin, N-terminal domain
58 SYN2interactorLpxD (PF04613, IPR020573): UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD
SPX (PF03105, IPR004331): SPX domain
Synapsin_C (PF02750, IPR020898): Synapsin, ATP binding domain
Synapsin_N (PF10581, IPR019736): Synapsin N-terminal
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
Synapsin (PF02078, IPR020897): Synapsin, N-terminal domain
59 SYPinteractorMARVEL (PF01284, IPR008253): Membrane-associating domain
60 SYT1interactorC2 (PF00168, IPR000008, SM00239): C2 domain
Comm (PF15957, IPR031878): Commissureless
61 VAMP2interactorSynaptobrevin (PF00957, IPR001388): Synaptobrevin
PRIMA1 (PF16101): Proline-rich membrane anchor 1
62 VSNL1suppressorIL3 (PF02059, IPR002183): Interleukin-3
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair

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