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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BM707746 is the fusion of parental proteins COL8A2, FHAD1 (from a repository: Sat Sep 21 07:54:15 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)15
The number (and %) of the onco-proteins4 (26.67 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)16 (15.24 %)
The number (and %) of affected PPIs14 (87.50 %)
The number of possible different fusions2
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.5345
The network average Clustering coefficient0.134
The number (and %) of a zero Clustering coefficients12 (80.00 %)
The number (and %) of a zero Betweenness Centrality14 (93.33 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: FHAD1,COL8A2 All fusions
: BM707746;
Proteins found in more fusions COL4A2 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BM707746chimera140.011180.000C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
SlyX (PF04102, IPR007236): SlyX
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3958 (PF13125, IPR025014): Protein of unknown function (DUF3958)
2 COL14A1interactor100CBM_4_9 (PF02018, IPR003305): Carbohydrate binding domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
3 COL18A1oncoprotein100Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF959 (PF06121, IPR010363): Domain of Unknown Function (DUF959)
Endostatin (PF06482, IPR010515): Collagenase NC10 and Endostatin
Fz (PF01392, IPR020067, SM00063): Fz domain
Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily
4 COL2A1interactor100COLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
5 COL4A2protein found in more fusions200C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
6 COL5A1interactor100COLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
7 COL8A1interactor100C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
8 COLEC12interactor100Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
Filament (PF00038, IPR001664): Intermediate filament protein
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
9 COLGALT2interactor100Aminotran_4 (PF01063, IPR001544): Amino-transferase class IV
Glyco_transf_25 (PF01755, IPR002654): Glycosyltransferase family 25 (LPS biosynthesis protein)
Glyco_tranf_2_4 (PF13704): Glycosyl transferase family 2
10 CRTAPinteractor21.0000Whi5 (PF08528, IPR013734): Whi5 like
YfiO (PF13525): Outer membrane lipoprotein
Stomagen (PF16851, IPR031753): Stomagen
11 FKBP14interactor100FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
12 FN1oncoprotein100fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
13 P3H1interactor21.0000TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
YfiO (PF13525): Outer membrane lipoprotein
2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
MCM_N (PF14551, IPR027925): MCM N-terminal domain
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
14 P4HA2interactor100P4Ha_N (PF08336, IPR013547): Prolyl 4-Hydroxylase alpha-subunit, N-terminal region
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
15 SGTAinteractor100TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
XPC-binding (PF09280, IPR015360): XPC-binding domain
TPR_17 (PF13431): Tetratricopeptide repeat
SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 COL8A2parental proteinC1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
2 FHAD1interactorDUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
FHA (PF00498, IPR000253, SM00240): FHA domain
IncA (PF04156, IPR007285): IncA protein
LPP (PF04728, IPR006817): Lipoprotein leucine-zipper
Phage_int_SAM_1 (PF02899, IPR004107): Phage integrase, N-terminal SAM-like domain
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
XhlA (PF10779, IPR019715): Haemolysin XhlA
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)

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