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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BG994562 is the fusion of parental proteins ACTA1, SYVN1 (from a repository: Mon Feb 27 10:56:52 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)102
The number (and %) of the onco-proteins30 (29.41 %)
The number (and %) of the tumor suppressors24 (23.53 %)
Total number of binary PPIs (saturation %)488 (9.47 %)
The number (and %) of affected PPIs101 (20.70 %)
The number of possible different fusions23
PPI diameter2
PPI radius1
The average degree of PPI8.686
Assortativity coefficient-0.2817
The network average Clustering coefficient0.550
The number (and %) of a zero Clustering coefficients13 (12.75 %)
The number (and %) of a zero Betweenness Centrality36 (35.29 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: ACTA1,SYVN1 All fusions
: BG994562;
Proteins found in more fusions ERBB3 (see 2 fusions); TPM2 (see 1 fusions); LGALS3 (see 2 fusions); APP (see 4 fusions); ETV6 (see 1 fusions); USP25 (see 1 fusions); ACTG1 (see 4 fusions); TPM2/MYH9 (see 1 fusions); CBL (see 1 fusions); MCM2 (see 1 fusions); KAT5 (see 3 fusions); CUL7 (see 2 fusions); SHC1 (see 1 fusions); CUL1 (see 3 fusions); EP300 (see 1 fusions); HDAC4 (see 1 fusions); GC (see 1 fusions); SGK1 (see 2 fusions); PRKCE (see 3 fusions); ERRFI1 (see 1 fusions); TP53 (see 3 fusions); CTNNBL1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BG994562chimera1010.0687550.323Actin (PF00022, IPR004000, SM00268): Actin
2 ABL1oncoprotein100.5289.096Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
3 ABLIM2interactor21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
Med27 (PF11571, IPR021627): Mediator complex subunit 27
AbLIM_anchor (PF16182, IPR032402): Putative adherens-junction anchoring region of AbLIM
4 ABLIM3interactor21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
zf-HYPF (PF07503, IPR011125): HypF finger
Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
AbLIM_anchor (PF16182, IPR032402): Putative adherens-junction anchoring region of AbLIM
5 ABRAinteractor30.6671.000Costars (PF14705, IPR027817): Costars
6 ACTBL2interactor130.38529.697Actin (PF00022, IPR004000, SM00268): Actin
7 ACTG1protein found in more fusions290.225234.760Actin (PF00022, IPR004000, SM00268): Actin
8 AKT1oncoprotein130.25836.343PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
9 AMOToncoprotein31.0000FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
Gastrin (PF00918, IPR001651, SM00029): Gastrin/cholecystokinin family
DUF2162 (PF09930, IPR017199): Predicted transporter (DUF2162)
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
10 APC2oncoprotein100APC_basic (PF05956, IPR009234): APC basic domain
APC_r (PF05923): APC repeat
Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
SAMP (PF05924, IPR009224): SAMP Motif
Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein
Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
Arm_APC_u3 (PF16629): Armadillo-associated region on APC
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
11 APPprotein found in more fusions250.123210.308APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
12 ARRB1interactor100.37814.705Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
13 BIN1suppressor31.0000BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
14 BRK1interactor50.9000.500DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
15 BTKsuppressor70.4005.638BTK (PF00779, IPR001562, SM00107): BTK motif
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
16 CAPZA2interactor160.47533.517F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
17 CBLsuppressor120.52712.510Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
18 CCT2interactor150.41933.242Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
19 CCT4interactor120.54510.554Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
20 CCT5interactor110.6365.940Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
21 CDH2interactor21.0000Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
Cadherin_3 (PF16184): Cadherin-like
22 CDK2suppressor240.39582.304Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
23 CDKN2Asuppressor130.41026.632Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
24 CEP57interactor40.5001.400Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
TRIQK (PF15168, IPR024842): Triple QxxK/R motif-containing protein family
25 CNN1suppressor21.0000Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
26 CTNNBL1protein found in more fusions200Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DASH_Dad4 (PF08650, IPR013959): DASH complex subunit Dad4
CTNNBL (PF08216, IPR013180, SM01156): Catenin-beta-like, Arm-motif containing nuclear
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
27 CUL1suppressor130.48514.098Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
28 CUL7protein found in more fusions140.43622.952ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
29 DHX9oncoprotein120.37922.917DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
30 DMAP1interactor70.9050.733DMAP1 (PF05499, IPR008468): DNA methyltransferase 1-associated protein 1 (DMAP1)
SANT_DAMP1_like (PF16282, IPR032563): SANT/Myb-like domain of DAMP1
31 DMC1interactor200Rad51 (PF08423, IPR013632): Rad51
HHH_5 (PF14520): Helix-hairpin-helix domain
32 DMDsuppressor50.6001.852CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus
IncA (PF04156, IPR007285): IncA protein
Spectrin (PF00435, IPR002017): Spectrin repeat
WW (PF00397, IPR001202, SM00456): WW domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DinB_2 (PF12867, IPR024775): DinB superfamily
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
33 DNASE1interactor100Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
34 DNMBPinteractor30.6671.000BAR (PF03114, IPR004148, SM00721): BAR domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
IncA (PF04156, IPR007285): IncA protein
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
35 EP300oncoprotein130.36425.471Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
36 ERBB3oncoprotein80.4767.733Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
37 ERRFI1suppressor60.7001.133GTPase_binding (PF09027, IPR015116): GTPase binding
Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6
38 ETV6suppressor31.0000Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
39 FAF2interactor80.3818.667DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
UBX (PF00789, IPR001012, SM00166): UBX domain
Thioredoxin_7 (PF13899): Thioredoxin-like
UBA_4 (PF14555): UBA-like domain
40 FSCN1oncoprotein41.0000Fascin (PF06268, IPR022768): Fascin domain
41 GCprotein found in more fusions200VitD-bind_III (PF09164, IPR015247): Vitamin D binding protein, domain III
Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
42 GPR37interactor21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
43 HDAC1suppressor160.37140.840FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
44 HDAC4oncoprotein50.6671.167Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
45 HDAC8interactor100DNase-RNase (PF02577, IPR003729): Bifunctional nuclease
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
46 HSPB2interactor41.0000Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
47 HTRA2suppressor31.0000Peptidase_S32 (PF05579, IPR008760): Equine arteritis virus serine endopeptidase S32
PDZ_2 (PF13180, IPR001478): PDZ domain
Trypsin_2 (PF13365): Trypsin-like peptidase domain
48 IGF1Roncoprotein70.4763.306fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
49 ISG15suppressor70.3337.607ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
50 KAT5suppressor150.41838.658MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
51 KLHL20interactor200BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
52 LGALS3oncoprotein41.0000Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
53 LIMA1suppressor190.47442.327LIM (PF00412, IPR001781, SM00132): LIM domain
ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
54 LRCH3interactor50.6002.056CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
55 MARK4oncoprotein31.0000KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
56 MCM2oncoprotein210.29573.525AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
57 MIB2oncoprotein100Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
KOW (PF00467, IPR005824, SM00739): KOW motif
MIB_HERC2 (PF06701, IPR010606): Mib_herc2
TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
58 MLPHinteractor100Dpy-30 (PF05186, IPR007858): Dpy-30 motif
Rab_eff_C (PF04698, IPR006788): Rab effector MyRIP/melanophilin C-terminus
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
RIC3 (PF15361, IPR032763): Resistance to inhibitors of cholinesterase homologue 3
59 MORF4L1interactor100.6675.817MRG (PF05712, IPR026541): MRG
Fmp27_WPPW (PF10359, IPR019449): RNA pol II promoter Fmp27 protein domain
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
60 MORF4L2interactor70.9050.733MRG (PF05712, IPR026541): MRG
61 MRGBPinteractor61.0000Eaf7 (PF07904, IPR012423): Chromatin modification-related protein EAF7
62 MYH9suppressor260.326138.749IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
63 MYO18Ainteractor130.67911.818Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
64 MYO1Cinteractor190.45649.987IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
65 NCKAP1interactor60.5335.533Nckap1 (PF09735, IPR019137): Membrane-associated apoptosis protein
66 NCOA3oncoprotein70.6194.019DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518)
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
SRC-1 (PF08832, IPR014935): Steroid receptor coactivator
PAS_11 (PF14598): PAS domain
DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927)
NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
67 NRAPinteractor21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat
68 NTRK1oncoprotein290.254186.662I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
69 OBSL1interactor120.5827.434BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
70 PCYT1Binteractor21.0000ApoC-I (PF04691, IPR006781): Apolipoprotein C-I (ApoC-1)
CTP_transf_like (PF01467, IPR004821): Cytidylyltransferase-like
FTO_CTD (PF12934, IPR024366): FTO C-terminal domain
71 PHACTR1interactor21.0000BAF1_ABF1 (PF04684, IPR006774): BAF1 / ABF1 chromatin reorganising factor
FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
RPEL (PF02755, IPR004018, SM00707): RPEL repeat
72 POLR1Binteractor40.8330.500RNA_pol_Rpa2_4 (PF06883, IPR009674): RNA polymerase I, Rpa2 specific domain
RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
73 POU5F1oncoprotein41.0000Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
74 PPP1CAsuppressor170.44940.927Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
75 PPP1CBinteractor170.54427.366Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
76 PPP1R9Binteractor80.6793.019PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Stm1_N (PF09598, IPR019084): Stm1
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
NuDC (PF16273, IPR032572): Nuclear distribution C domain
77 PRKCEsuppressor50.5001.500C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
78 RELAoncoprotein100.5568.908DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
79 RPS6KB1interactor60.7001.500Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
80 RPS6KB2interactor100.28919.321Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
81 RRN3interactor40.8330.500RRN3 (PF05327, IPR007991): RNA polymerase I specific transcription initiation factor RRN3
82 SFNsuppressor120.30923.00014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
83 SGK1oncoprotein200Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
PX (PF00787, IPR001683, SM00312): PX domain
84 SHC1oncoprotein150.39632.240PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
85 SMARCD1interactor40.6670.375ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit
DivIC (PF04977, IPR007060): Septum formation initiator
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
86 SPTAN1oncoprotein190.42158.395EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Tetrabrachion (PF11401, IPR021535): Tetrabrachion
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
87 TAGLNsuppressor21.0000Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
88 TESsuppressor61.0000LIM (PF00412, IPR001781, SM00132): LIM domain
PET (PF06297, IPR010442): PET Domain
PSCyt3 (PF07627, IPR013039): Protein of unknown function (DUF1588)
Ig_Tie2_1 (PF10430, IPR018941): Tie-2 Ig-like domain 1
89 TNNI3Kinteractor100Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
90 TP53suppressor250.286110.190DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
91 TPM2protein found in more fusions80.7621.915DASH_Spc19 (PF08287, IPR013251): Spc19
Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
92 TRAF3IP1interactor50.6001.750MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
93 TRIM55interactor40.6671.000Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
NABP (PF07990, IPR012940): Nucleic acid binding protein NABP
zf-HIT (PF04438, IPR007529): HIT zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
94 TRIM63interactor50.5003.000DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349)
KIP1 (PF07765, IPR011684): KIP1-like protein
RED_C (PF07807, IPR012492): RED-like protein C-terminal region
zf-HIT (PF04438, IPR007529): HIT zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
YceG_bac (PF14266, IPR025647): Putative component of 'biosynthetic module'
95 TRIP6interactor100DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
LIM (PF00412, IPR001781, SM00132): LIM domain
96 TSC1suppressor31.0000Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Hamartin (PF04388, IPR007483): Hamartin protein
97 UBAC2interactor21.0000Rhomboid (PF01694, IPR022764): Rhomboid family
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
98 UBE3Aoncoprotein90.4647.630HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
99 UBL4Ainteractor50.5001.950ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
100 USP25protein found in more fusions31.0000UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
UBA_4 (PF14555): UBA-like domain
101 VIMsuppressor160.29545.746Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
102 XPO6interactor100IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ACTA1parental proteinActin (PF00022, IPR004000, SM00268): Actin
2 AMFRoncoproteinCUE (PF02845, IPR003892, SM00546): CUE domain
UbiA (PF01040, IPR000537): UbiA prenyltransferase family
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
3 ANXA8interactorAnnexin (PF00191, IPR018502, SM00335): Annexin
4 APOBinteractorDUF1081 (PF06448, IPR009454): Domain of Unknown Function (DUF1081)
DUF1943 (PF09172, IPR015255, SM01169): Domain of unknown function (DUF1943)
Phage_holin_6_1 (PF09682, IPR010026): Bacteriophage holin of superfamily 6 (Holin_LLH)
Vitellogenin_N (PF01347, IPR001747, SM00638): Lipoprotein amino terminal region
DUF2807 (PF10988, IPR021255): Putative auto-transporter adhesin, head GIN domain
ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal
5 ASGR1interactorLectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
6 ASGR2interactorUL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
7 ATF6interactorbZIP_1 (PF00170, IPR004827): bZIP transcription factor
DUF2749 (PF10907, IPR024475): Protein of unknown function (DUF2749)
8 ATN1interactorAtrophin-1 (PF03154, IPR002951): Atrophin-1 family
9 ATP6AP1interactorATP-synt_S1 (PF05827, IPR024722): Vacuolar ATP synthase subunit S1 (ATP6S1)
10 ATXN3interactorJosephin (PF02099, IPR006155): Josephin
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
11 AUP1interactorCUE (PF02845, IPR003892, SM00546): CUE domain
12 BAG1oncoproteinBAG (PF02179, IPR003103, SM00264): BAG domain
Presenilin (PF01080, IPR001108): Presenilin
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
13 BAG6interactorDUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
14 BSGinteractorIg_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
15 CFL1interactorCofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
16 CLUsuppressorClusterin (PF01093, IPR000753): Clusterin
17 COTL1oncoproteinCofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
18 CSNK1A1suppressorPkinase (PF00069, IPR000719): Protein kinase domain
19 DERL1interactorDER1 (PF04511, IPR007599): Der1-like family
20 DERL2interactorDER1 (PF04511, IPR007599): Der1-like family
21 DSTNinteractorCofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
22 DVL1P1interactorNA
23 ERLEC1interactorPRKCSH (PF07915, IPR012913): Glucosidase II beta subunit-like protein
PRKCSH_1 (PF13015, IPR009011): Glucosidase II beta subunit-like protein
24 ERLIN1interactorRibosomal_L33 (PF00471, IPR001705): Ribosomal protein L33
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
25 ERLIN2interactorBand_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
26 ERN1interactorPkinase (PF00069, IPR000719): Protein kinase domain
PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
Ribonuc_2-5A (PF06479, IPR010513): Ribonuclease 2-5A
CytochromB561_N (PF09786, IPR019176): Cytochrome B561, N terminal
PQQ_2 (PF13360, IPR002372): PQQ-like domain
27 FAM8A1interactorRDD (PF06271, IPR010432): RDD family
28 FDFT1interactorSQS_PSY (PF00494, IPR002060): Squalene/phytoene synthase
29 FOXRED2interactorPyr_redox_3 (PF13738): Pyridine nucleotide-disulphide oxidoreductase
30 GABRA1interactorNeur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
31 GLRA2interactorNeur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
32 GSNsuppressorGelsolin (PF00626, IPR007123): Gelsolin repeat
33 HERPUD1oncoproteinNeisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
34 HEY1oncoproteinHairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
HTH_Crp_2 (PF13545, IPR012318): Crp-like helix-turn-helix domain
35 HEY2interactorHairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
36 HFEoncoproteinDUF912 (PF06024, IPR009261): Nucleopolyhedrovirus protein of unknown function (DUF912)
MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
37 HLA-AoncoproteinDUF202 (PF02656, IPR003807): Domain of unknown function (DUF202)
MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
38 HMGCRoncoproteinHMG-CoA_red (PF00368, IPR002202): Hydroxymethylglutaryl-coenzyme A reductase
Sterol-sensing (PF12349, IPR000731): Sterol-sensing domain of SREBP cleavage-activation
39 HMOX1interactorHeme_oxygenase (PF01126, IPR016053): Heme oxygenase
40 HSPA5oncoproteinHSP70 (PF00012, IPR013126): Hsp70 protein
41 HTTinteractorHEAT (PF02985, IPR000357): HEAT repeat
SPX (PF03105, IPR004331): SPX domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF3652 (PF12372, IPR024613): Huntingtin protein region
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
42 IGHMinteractorC2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
43 MAPK14oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
44 MBTPS2interactorFixS (PF03597, IPR004714): Cytochrome oxidase maturation protein cbb3-type
Peptidase_M50 (PF02163, IPR008915): Peptidase family M50
DUF4667 (PF15700, IPR031426): Domain of unknown function (DUF4667)
45 NAAAinteractorCBAH (PF02275, IPR003199): Linear amide C-N hydrolases, choloylglycine hydrolase family
NAAA-beta (PF15508, IPR029130): beta subunit of N-acylethanolamine-hydrolyzing acid amidase
46 OS9interactorDNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
Nucleo_P87 (PF07267, IPR009893): Nucleopolyhedrovirus capsid protein P87
PRKCSH (PF07915, IPR012913): Glucosidase II beta subunit-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
PRKCSH_1 (PF13015, IPR009011): Glucosidase II beta subunit-like protein
47 PDIA2interactorThioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
48 PFDN1interactorPrefoldin_2 (PF01920, IPR002777): Prefoldin subunit
49 PMP22interactorPBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
50 PORinteractorFAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
51 PPARGC1BinteractorCwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
Mak16 (PF04874, IPR006958): Mak16 protein C-terminal region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
DUF4632 (PF15451, IPR027952): Domain of unknown function (DUF4632)
PBP_N (PF17093, IPR031375): Penicillin-binding protein N-terminus
52 PPP1R1AoncoproteinDARPP-32 (PF05395, IPR008466): Protein phosphatase inhibitor 1/DARPP-32
53 PSMA1interactorProteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
54 PSMA2interactorProteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
55 PSMA3interactorProteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
56 PSMA5oncoproteinProteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
57 PSMA6interactorProteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
58 PSMA7interactorProteasome (PF00227, IPR001353): Proteasome subunit
Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
59 PSMB1interactorProteasome (PF00227, IPR001353): Proteasome subunit
60 PSMB2interactorProteasome (PF00227, IPR001353): Proteasome subunit
61 PSMB3interactorProteasome (PF00227, IPR001353): Proteasome subunit
62 PSMB4interactorIntegrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Proteasome (PF00227, IPR001353): Proteasome subunit
63 PSMB6interactorDUF1502 (PF07397, IPR010871): Repeat of unknown function (DUF1502)
Proteasome (PF00227, IPR001353): Proteasome subunit
64 PSMB7interactorProteasome (PF00227, IPR001353): Proteasome subunit
Pr_beta_C (PF12465, IPR024689): Proteasome beta subunits C terminal
65 PSMD1interactorPA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin)
PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
HEAT_2 (PF13646): HEAT repeats
66 PSMD2oncoproteinPC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
THAP (PF05485, IPR006612, SM00980): THAP domain
HEAT_2 (PF13646): HEAT repeats
67 PSMD7interactorJAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
Auts2 (PF15336): Autism susceptibility gene 2 protein
Coilin_N (PF15862, IPR031722): Coilin N-terminus
68 PTPN22interactorY_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
69 RER1interactorRer1 (PF03248, IPR004932): Rer1 family
70 SARAFinteractorSARAF (PF06682, IPR009567): SOCE-associated regulatory factor of calcium homoeostasis
71 SCINinteractorGelsolin (PF00626, IPR007123): Gelsolin repeat
72 SEL1Loncoproteinfn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
73 SELENOSinteractorSelenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS)
DUF3326 (PF11805, IPR021763): Protein of unknown function (DUF3326)
74 SHHoncoproteinHH_signal (PF01085, IPR000320): Hedgehog amino-terminal signalling domain
Hint (PF01079, IPR001767): Hint module
75 SMARCB1suppressorSNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1
76 SNCAinteractorSynuclein (PF01387, IPR001058): Synuclein
77 STXBP5LinteractorLgl_C (PF08596, IPR013905): Lethal giant larvae(Lgl) like, C-terminal
LLGL (PF08366, IPR013577): LLGL2
Serglycin (PF04360, IPR007455): Serglycin
Synaptobrevin (PF00957, IPR001388): Synaptobrevin
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
RAB3GAP2_N (PF14655, IPR032839): Rab3 GTPase-activating protein regulatory subunit N-terminus
78 SVIPinteractorSVIP (PF15811, IPR031632): Small VCP/p97-interacting protein
79 SYVN1parental proteinAlpha_GJ (PF03229, IPR004913): Alphavirus glycoprotein J
zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
80 TMEM129interactorTmpp129 (PF10272, IPR018801): Putative transmembrane protein precursor
81 TMSB4XinteractorThymosin (PF01290, IPR001152, SM00152): Thymosin beta-4 family
82 TMSB4YinteractorThymosin (PF01290, IPR001152, SM00152): Thymosin beta-4 family
83 TMUB1interactorDUF347 (PF03988, IPR007136): Repeat of Unknown Function (DUF347)
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF4227 (PF14004, IPR025321): Protein of unknown function (DUF4227)
84 TRAoncoproteinNA
85 TYRinteractorDUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
Tyrosinase (PF00264, IPR002227): Common central domain of tyrosinase
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
86 UBE2D2oncoproteinUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
87 UBE2D3interactorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
88 UBE2J1interactorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
ATPase-cat_bd (PF12156, IPR021993): Putative metal-binding domain of cation transport ATPase
89 UBE2UinteractorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
efb-c (PF12199, IPR021033): Extracellular fibrinogen binding protein C terminal
TMEM154 (PF15102, IPR028064): TMEM154 protein family
90 UBE2ZinteractorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
91 UBXN8interactorBap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
UBX (PF00789, IPR001012, SM00166): UBX domain
92 USP19interactorCS (PF04969, IPR007052): CS domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP19_linker (PF16602): Linker region of USP19 deubiquitinase
93 USP7oncoproteinMATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
94 VCPinteractorAAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
95 WBP1interactorWBP-1 (PF11669, IPR021684): WW domain-binding protein 1
96 WFS1interactorFixQ (PF05545, IPR008621): Cbb3-type cytochrome oxidase component FixQ
Cytochrome-c551 (PF10643, IPR019604): Photosystem P840 reaction-centre cytochrome c-551
HTH_16 (PF12645, IPR024760): Helix-turn-helix domain
Adipogenin (PF15202, IPR027938): Adipogenin
97 YOD1interactorOTU (PF02338, IPR003323): OTU-like cysteine protease
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
Ubiquitin_2 (PF14560, IPR027933): Ubiquitin-like domain

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