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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)49
The number (and %) of the onco-proteins20 (40.82 %)
The number (and %) of the tumor suppressors4 (8.16 %)
Total number of binary PPIs (saturation %)240 (20.41 %)
The number (and %) of affected PPIs48 (20.00 %)
The number of possible different fusions14
PPI diameter2
PPI radius1
The average degree of PPI8.776
Assortativity coefficient-0.2070
The network average Clustering coefficient0.505
The number (and %) of a zero Clustering coefficients6 (12.24 %)
The number (and %) of a zero Betweenness Centrality9 (18.37 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: SF1 All fusions
: BG987940;
Proteins found in more fusions CUL7 (see 2 fusions); HDAC5 (see 1 fusions); EWSR1 (see 2 fusions); PLOD2 (see 1 fusions); CUL3 (see 1 fusions); ATXN1 (see 3 fusions); HDAC4 (see 1 fusions); NFKB1 (see 2 fusions); NCOA1 (see 2 fusions); PRPF40A (see 2 fusions); FAF1 (see 2 fusions); U2AF2 (see 2 fusions); HNRNPL (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BG987940chimera480.1481354.493KH_1 (PF00013, IPR004088, SM00322): KH domain
SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain
2 APBB1interactor60.8001.333PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
WW (PF00397, IPR001202, SM00456): WW domain
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID)
3 ATXN1protein found in more fusions60.6003.667AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
4 CIAO1interactor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
5 CSNK2A2interactor60.5333.550Pkinase (PF00069, IPR000719): Protein kinase domain
6 CUL3protein found in more fusions210.29584.845Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
7 CUL7protein found in more fusions190.35952.862ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
8 EEDsuppressor120.40014.480WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
9 EFTUD2interactor140.35917.609EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
10 EIF4Binteractor60.8001.333RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3774 (PF12609, IPR022251): Wound-induced protein
PROL5-SMR (PF15621, IPR026288): Proline-rich submaxillary gland androgen-regulated family
11 EWSR1oncoprotein160.41033.086RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
12 FAF1protein found in more fusions60.8001.000UBX (PF00789, IPR001012, SM00166): UBX domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
AAA_11 (PF13086): AAA domain
UBA_4 (PF14555): UBA-like domain
13 FN1oncoprotein110.36416.274fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
14 FUSsuppressor140.49519.280Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
15 GARTinteractor80.5715.743AIRS (PF00586, IPR000728): AIR synthase related protein, N-terminal domain
AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain
Formyl_trans_N (PF00551, IPR002376): Formyl transferase
GARS_A (PF01071, IPR020561): Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
GARS_C (PF02843, IPR020560): Phosphoribosylglycinamide synthetase, C domain
GARS_N (PF02844, IPR020562): Phosphoribosylglycinamide synthetase, N domain
16 HADHinteractor21.00003HCDH (PF00725, IPR006108): 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
17 HDAC4oncoprotein80.6195.167Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
18 HDAC5protein found in more fusions110.42215.123Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
19 HNRNPLprotein found in more fusions140.39718.682RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
20 ITCHinteractor60.6002.515C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
21 ITGA4interactor110.6005.760FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
22 LLGL2interactor200Lgl_C (PF08596, IPR013905): Lethal giant larvae(Lgl) like, C-terminal
LLGL (PF08366, IPR013577): LLGL2
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
RAB3GAP2_N (PF14655, IPR032839): Rab3 GTPase-activating protein regulatory subunit N-terminus
23 MKRN3oncoprotein200zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal
Torus (PF16131, IPR032297): Torus domain
zf-3CxxC_2 (PF17180): Zinc-binding domain
24 NCOA1oncoprotein50.6671.333DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518)
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
SRC-1 (PF08832, IPR014935): Steroid receptor coactivator
PAS_11 (PF14598): PAS domain
DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927)
NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
25 NCOR2oncoprotein60.7332.500CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK)
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family
PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Spt20 (PF12090, IPR021950): Spt20 family
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518)
GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
26 NFKB1suppressor80.4769.667Death (PF00531, IPR000488, SM00005): Death domain
GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
27 NNTinteractor30.6670.167AlaDh_PNT_C (PF01262, IPR007698, SM01002): Alanine dehydrogenase/PNT, C-terminal domain
AlaDh_PNT_N (PF05222, IPR007886, SM01003): Alanine dehydrogenase/PNT, N-terminal domain
PNTB (PF02233, IPR012136): NAD(P) transhydrogenase beta subunit
PNTB_4TM (PF12769, IPR024605): 4TM region of pyridine nucleotide transhydrogenase, mitoch
28 NTRK1oncoprotein220.252109.883I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
29 OBSL1interactor150.49514.962BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
30 OSBPinteractor31.0000Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein
PH (PF00169, IPR001849, SM00233): PH domain
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
HlyD_D23 (PF16576, IPR032317): Barrel-sandwich domain of CusB or HlyD membrane-fusion
31 PLOD2protein found in more fusions50.8330.4002OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily
Anp1 (PF03452, IPR005109): Anp1
Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
32 PPARGC1Ainteractor40.6671.333Pap_E4 (PF02711, IPR003861): E4 protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RSRP (PF17069): Arginine/Serine-Rich protein 1
33 PPIDinteractor30.6670.200Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
34 PRPF40Aprotein found in more fusions130.6069.577FF (PF01846, IPR002713, SM00441): FF domain
MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain
Transformer (PF06495, IPR010519): Fruit fly transformer protein
WW (PF00397, IPR001202, SM00456): WW domain
YqzE (PF14038, IPR025622): YqzE-like protein
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus
SOBP (PF15279, IPR026092): Sine oculis-binding protein
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
35 RBM10interactor90.7143.363G-patch (PF01585, IPR000467, SM00443): G-patch domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
GSIII_N (PF12437, IPR022147): Glutamine synthetase type III N terminal
G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site
zf-C2H2_4 (PF13894): C2H2-type zinc finger
DUF4337 (PF14235, IPR025570): Domain of unknown function (DUF4337)
FAM176 (PF14851): FAM176 family
36 SBDSoncoprotein21.0000SBDS (PF01172, IPR019783): Shwachman-Bodian-Diamond syndrome (SBDS) protein
SBDS_C (PF09377, IPR018978): SBDS protein C-terminal domain
37 SF3A1interactor150.50522.294TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Surp (PF01805, IPR000061, SM00648): Surp module
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
38 SF3A2interactor130.60311.905Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32
PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
zf-met (PF12874): Zinc-finger of C2H2 type
ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix
SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
39 SIN3Aoncoprotein70.4768.556Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
40 SORCS3interactor100PKD (PF00801, IPR000601, SM00089): PKD domain
Sortilin_C (PF15901, IPR031777): Sortilin, neurotensin receptor 3, C-terminal
Sortilin-Vps10 (PF15902, IPR031778): Sortilin, neurotensin receptor 3
41 SUPT5Hinteractor90.4449.716KOW (PF00467, IPR005824, SM00739): KOW motif
Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
42 TAF15oncoprotein60.6001.447API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
GRP (PF07172, IPR010800): Glycine rich protein family
Presenilin (PF01080, IPR001108): Presenilin
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
43 TCERG1interactor100.5568.058FF (PF01846, IPR002713, SM00441): FF domain
WW (PF00397, IPR001202, SM00456): WW domain
Folliculin (PF11704, IPR021713): Vesicle coat protein involved in Golgi to plasma membrane transport
DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807)
DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886)
Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO
FAM150 (PF15129, IPR029364): FAM150 family
44 U2AF2protein found in more fusions170.51728.898RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
45 VCAM1interactor70.6671.386C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
46 WBP4interactor70.6191.894CDC45 (PF02724, IPR003874): CDC45-like protein
WW (PF00397, IPR001202, SM00456): WW domain
zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
TMCO5 (PF14992, IPR026617): TMCO5 family
47 WDR83interactor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
48 XRCC5suppressor130.39417.659Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
49 ZFP41interactor100zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ACTL6AinteractorActin (PF00022, IPR004000, SM00268): Actin
2 ALDOCinteractorGlycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
3 BCAS2interactorBCAS2 (PF05700, IPR008409): Breast carcinoma amplified sequence 2 (BCAS2)
ZapB (PF06005, IPR009252): Cell division protein ZapB
4 CAB39interactorMo25 (PF08569, IPR013878): Mo25-like
5 CCDC25interactorDUF814 (PF05670, IPR008532): Domain of unknown function (DUF814)
Phage_Mu_Gam (PF07352, IPR009951): Bacteriophage Mu Gam like protein
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
6 CCDC8interactorBorrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
7 CDC42oncoproteinRas (PF00071, IPR001806, SM00173): Ras family
8 CIRBPoncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
9 CNN2interactorCalponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
10 DDX17interactorCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Ferritin (PF00210, IPR008331): Ferritin-like domain
GRP (PF07172, IPR010800): Glycine rich protein family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
11 EMC2interactorTPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_19 (PF14559): Tetratricopeptide repeat
Alkyl_sulf_dimr (PF14863, IPR029228): Alkyl sulfatase dimerisation
12 FAM168AinteractorTCRP1 (PF14944, IPR029247): Tongue Cancer Chemotherapy Resistant Protein 1
13 FARSBinteractorB3_4 (PF03483, IPR005146, SM00873): B3/4 domain
B5 (PF03484, IPR005147, SM00874): tRNA synthetase B5 domain
14 GAS7oncoproteinDUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
WW (PF00397, IPR001202, SM00456): WW domain
YscO (PF07321, IPR009929): Type III secretion protein YscO
SH3_9 (PF14604, IPR001452): Variant SH3 domain
WW_FCH_linker (PF16623): Unstructured linker region between on GAS7 protein
15 GFPT1interactorSIS (PF01380, IPR001347): SIS domain
GATase_6 (PF13522): Glutamine amidotransferase domain
16 HIRIP3interactorCHZ (PF09649, IPR019098, SM01082): Histone chaperone domain CHZ
17 HIST1H4AinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
18 HNRNPFinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
19 HNRNPH1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
20 HNRNPH2interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
21 HNRNPKoncoproteinROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
22 HNRNPUL1interactorMito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Rox3 (PF08633, IPR013942): Rox3 mediator complex subunit
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
23 HSDL2interactoradh_short (PF00106, IPR002198): short chain dehydrogenase
SCP2 (PF02036, IPR003033): SCP-2 sterol transfer family
24 HSPH1oncoproteinHSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
25 IL7Rinteractorfn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
26 ILF3oncoproteindsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
27 IREB2interactorAconitase (PF00330, IPR001030): Aconitase family (aconitate hydratase)
Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
28 KLC3interactorTPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
TPR_12 (PF13424): Tetratricopeptide repeat
29 KRTAP26-1interactorPMG (PF05287, IPR007951): PMG protein
30 LMNAinteractorFilament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
31 MAPK8oncoproteinDUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
32 METTL22interactorMethyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
33 MPLKIPinteractorMPLKIP (PF15502, IPR028265): M-phase-specific PLK1-interacting protein
34 NARSinteractortRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N)
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
35 PARD6BinteractorPB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
36 PGK1interactorPGK (PF00162, IPR001576): Phosphoglycerate kinase
37 PLAAinteractorPFU (PF09070, IPR015155): PFU (PLAA family ubiquitin binding)
PUL (PF08324, IPR013535): PUL domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
38 PLSCR1interactorScramblase (PF03803, IPR005552): Scramblase
39 PMLsuppressorzf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
40 PRMT2interactorPRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
SH3_9 (PF14604, IPR001452): Variant SH3 domain
41 PSMA3interactorProteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
42 RANBP3oncoproteinRan_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
43 RBM17interactorG-patch (PF01585, IPR000467, SM00443): G-patch domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
Slu7 (PF11708, IPR021715): Pre-mRNA splicing Prp18-interacting factor
44 RBM4suppressorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCHC (PF00098, IPR001878): Zinc knuckle
CompInhib_SCIN (PF11546, IPR021612): Staphylococcal complement inhibitor SCIN
45 RBM7interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
46 RBPMSinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
47 RNF41interactorSina (PF03145, IPR018121): Seven in absentia protein family
USP8_interact (PF08941, IPR015036): USP8 interacting
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
48 RPL24interactorMAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
49 SAMHD1interactorHD (PF01966, IPR006674): HD domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
50 SEPT11interactorSeptin (PF00735, IPR000038): Septin
DUF3080 (PF11279, IPR021431): Protein of unknown function (DUF3080)
51 SF1parental proteinUPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181)
zf-CCHC (PF00098, IPR001878): Zinc knuckle
KH_1 (PF00013, IPR004088, SM00322): KH domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain
52 SF3B4interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
53 SRP9interactorSRP9-21 (PF05486): Signal recognition particle 9 kDa protein (SRP9)
54 SRPRBinteractorMHYT (PF03707, IPR005330): Bacterial signalling protein N terminal repeat
SRPRB (PF09439, IPR019009): Signal recognition particle receptor beta subunit
55 STIM1interactorAPG6 (PF04111, IPR007243): Autophagy protein Apg6
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SSP160 (PF06933, IPR009701): Special lobe-specific silk protein SSP160
DUF4446 (PF14584, IPR027981): Protein of unknown function (DUF4446)
SOAR (PF16533, IPR032393): STIM1 Orai1-activating region
56 STOMinteractorBand_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
57 SUZ12suppressorDUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
58 TAGLNsuppressorCalponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
59 TKTinteractorTransket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
Transketolase_N (PF00456, IPR005474): Transketolase, thiamine diphosphate binding domain
60 TMED4interactorEMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD
61 TOMM40interactorPorin_3 (PF01459, IPR027246): Eukaryotic porin
62 TRIM23interactorArf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
FemAB (PF02388, IPR003447): FemAB family
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
63 TRIM69interactorDUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
SPRY (PF00622, IPR003877, SM00449): SPRY domain
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
DZR (PF12773, IPR025874): Double zinc ribbon
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
64 TROVE2interactorTROVE (PF05731, IPR008858): TROVE domain
DUF2201 (PF09967, IPR018698): VWA-like domain (DUF2201)
65 UBE2L3interactorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
66 UBE2NinteractorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
67 VAMP2interactorSynaptobrevin (PF00957, IPR001388): Synaptobrevin
PRIMA1 (PF16101): Proline-rich membrane anchor 1
68 VDAC1interactorPorin_3 (PF01459, IPR027246): Eukaryotic porin
69 VDAC3interactorPorin_3 (PF01459, IPR027246): Eukaryotic porin
70 WDR77oncoproteinLT-IIB (PF06453, IPR010503): Type II heat-labile enterotoxin , B subunit (LT-IIB)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
71 WWP2interactorWW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
72 XPO7interactorIBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
73 ZC3H11AinteractorBul1_C (PF04426, IPR022794): Bul1 C terminus
Sec62 (PF03839, IPR004728): Translocation protein Sec62
zf-CCCH_3 (PF15663): Zinc-finger containing family
74 ZFRinteractorDZF (PF07528, IPR006561, SM00572): DZF domain
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
zf-met (PF12874): Zinc-finger of C2H2 type
75 ZNF461interactorFer4 (PF00037, IPR001450): 4Fe-4S binding domain
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-trcl (PF13451, IPR025306): Probable zinc-ribbon domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger

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