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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BG340155 is the fusion of parental proteins HDGF, FBXW2 (from a repository: Tue Feb 14 21:34:13 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)119
The number (and %) of the onco-proteins39 (32.77 %)
The number (and %) of the tumor suppressors7 (5.88 %)
Total number of binary PPIs (saturation %)763 (10.87 %)
The number (and %) of affected PPIs118 (15.47 %)
The number of possible different fusions22
PPI diameter2
PPI radius1
The average degree of PPI12.218
Assortativity coefficient-0.2807
The network average Clustering coefficient0.581
The number (and %) of a zero Clustering coefficients4 (3.36 %)
The number (and %) of a zero Betweenness Centrality20 (16.81 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: HDGF,FBXW2 All fusions
: BG340155;
Proteins found in more fusions RBMX (see 3 fusions); APP (see 4 fusions); SRSF2 (see 1 fusions); STAU1 (see 2 fusions); CKAP4 (see 5 fusions); HSP90AA1 (see 2 fusions); U2AF2 (see 2 fusions); CUL1 (see 3 fusions); MAPK14 (see 1 fusions); PSME3 (see 2 fusions); UBE2D2 (see 2 fusions); EWSR1 (see 2 fusions); EIF2AK2 (see 1 fusions); PRKDC (see 3 fusions); RACK1 (see 3 fusions); DDX17 (see 3 fusions); PARP1 (see 1 fusions); EP300 (see 1 fusions); DDX5 (see 1 fusions); RPA1 (see 1 fusions); NCL (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BG340155chimera1180.0887481.505WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
F-box-like (PF12937, IPR001810): F-box-like
2 ABCF1interactor80.7501.723ABC_tran (PF00005, IPR003439): ABC transporter
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
KOG2701 (PF09762, IPR019159): Coiled-coil domain-containing protein (DUF2037)
ABC_tran_Xtn (PF12848, IPR032781): ABC transporter
AAA_18 (PF13238): AAA domain
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
3 ACTL6Ainteractor90.41710.357Actin (PF00022, IPR004000, SM00268): Actin
4 AHCYinteractor70.8000.496AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
5 ALYREFinteractor170.53324.597FYTT (PF07078, IPR009782): Forty-two-three protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
6 APPprotein found in more fusions250.163146.218APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
7 ASB6interactor40.8330.400Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
8 ATAD3Ainteractor70.6672.674AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
DUF3523 (PF12037, IPR021911): Domain of unknown function (DUF3523)
9 BAZ1Binteractor40.6671.667D5_N (PF08706, IPR014818, SM00885): D5 N terminal like
DDT (PF02791, IPR004022, SM00571): DDT domain
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
PHD (PF00628, IPR019787, SM00249): PHD-finger
YL1 (PF05764, IPR008895): YL1 nuclear protein
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3635 (PF12330, IPR024604): Domain of unknown function (DUF3635)
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
FAM176 (PF14851): FAM176 family
WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1
WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif
10 BMS1interactor21.0000AARP2CN (PF08142, IPR012948, SM00785): AARP2CN (NUC121) domain
RIBIOP_C (PF04950, IPR007034): 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
E7 (PF00527, IPR000148): E7 protein, Early protein
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
NOA36 (PF06524, IPR010531): NOA36 protein
11 BTG1oncoprotein31.0000BTG (PF07742, IPR002087, SM00099): BTG family
12 BTG2suppressor31.0000BTG (PF07742, IPR002087, SM00099): BTG family
13 BUB3interactor60.9330.154WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
14 CDC34oncoprotein50.8330.400UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
15 CDC5Linteractor380.306198.646OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
16 CDK1oncoprotein110.44412.645Pkinase (PF00069, IPR000719): Protein kinase domain
17 CKAP4protein found in more fusions70.4671.443DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
FPP (PF05911, IPR008587): Filament-like plant protein, long coiled-coil
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
18 CROCCinteractor100APG6 (PF04111, IPR007243): Autophagy protein Apg6
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Rho_Binding (PF08912, IPR015008): Rho Binding
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
SOGA (PF11365, IPR027881): Protein SOGA
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
19 CUL1suppressor600.186933.218Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
20 DDX1oncoprotein110.7273.942DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
21 DDX17protein found in more fusions200.54421.388CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Ferritin (PF00210, IPR008331): Ferritin-like domain
GRP (PF07172, IPR010800): Glycine rich protein family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
22 DDX21interactor170.44131.053CRT10 (PF08728, IPR014839): CRT10
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
GUCT (PF08152, IPR012562): GUCT (NUC152) domain
Sulfatase (PF00884, IPR000917): Sulfatase
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
23 DDX47interactor70.7141.678DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
24 DDX5oncoprotein190.58217.635DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
25 DDX50interactor41.0000CDC45 (PF02724, IPR003874): CDC45-like protein
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
GUCT (PF08152, IPR012562): GUCT (NUC152) domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
26 DEKoncoprotein50.4004.083DEK_C (PF08766, IPR014876): DEK C terminal domain
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
SAP (PF02037, IPR003034, SM00513): SAP domain
Bud13 (PF09736, IPR018609): Pre-mRNA-splicing factor of RES complex
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
27 DHX15interactor200.45346.287DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AAA_29 (PF13555): P-loop containing region of AAA domain
28 DHX30interactor90.6393.122Bombolitin (PF08096, IPR012534): Bombolitin family
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
29 DHX9oncoprotein290.38995.341DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
30 DNAJA1interactor90.7222.621DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
31 EFTUD2interactor150.6597.084EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
32 EIF2AK2oncoprotein130.45514.325dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Pkinase (PF00069, IPR000719): Protein kinase domain
33 EIF5Binteractor31.0000GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
MIase (PF02426, IPR026029): Muconolactone delta-isomerase
NOA36 (PF06524, IPR010531): NOA36 protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
IF-2 (PF11987, IPR023115): Translation-initiation factor 2
DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807)
GTP_EFTU_D4 (PF14578, IPR029459): Elongation factor Tu domain 4
DUF4632 (PF15451, IPR027952): Domain of unknown function (DUF4632)
Coilin_N (PF15862, IPR031722): Coilin N-terminus
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
34 ENO1oncoprotein120.51513.114Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
35 EP300oncoprotein150.28638.441Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
36 EWSR1oncoprotein290.265152.230RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
37 FBXO17interactor50.9000.286FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
38 FBXO6interactor300.193176.914FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
39 FBXO7interactor70.5246.567Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
PI31_Prot_N (PF11566, IPR021625): PI31 proteasome regulator N-terminal
F-box-like (PF12937, IPR001810): F-box-like
40 FBXW8interactor80.46412.269WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
41 GCM1interactor31.0000DUF1272 (PF06906, IPR010696): Protein of unknown function (DUF1272)
GCM (PF03615, IPR003902): GCM motif protein
42 GNL3interactor60.8670.432GN3L_Grn1 (PF08701, IPR014813): GNL3L/Grn1 putative GTPase
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
FAM176 (PF14851): FAM176 family
43 GTPBP1interactor50.5000.882GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
44 HNRNPA2B1oncoprotein210.42444.273RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
45 HNRNPA3oncoprotein130.6795.483IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
46 HNRNPUinteractor400.251337.355CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
47 HSD17B10interactor100.6225.285adh_short (PF00106, IPR002198): short chain dehydrogenase
48 HSP90AA1oncoprotein240.31296.683HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
49 HSPA9oncoprotein170.48521.802HSP70 (PF00012, IPR013126): Hsp70 protein
50 JUNoncoprotein140.35922.433bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
51 KAT2Ainteractor60.4003.900Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
52 KIF2Ainteractor41.0000Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
AAA_23 (PF13476): AAA domain
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
53 KPNA2interactor100.4677.580Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
54 KRT1interactor50.8001.333Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
Keratin_2_head (PF16208, IPR032444): Keratin type II head
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
55 KRT10interactor41.0000Filament (PF00038, IPR001664): Intermediate filament protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
56 KRT2interactor60.6004.667Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
57 LRRC59interactor60.6670.909Hid1 (PF12722): High-temperature-induced dauer-formation protein
LRR_8 (PF13855, IPR001611): Leucine rich repeat
DUF4366 (PF14283, IPR025376): Domain of unknown function (DUF4366)
58 LYARinteractor60.6671.086DEK_C (PF08766, IPR014876): DEK C terminal domain
zf-LYAR (PF08790, IPR014898): LYAR-type C2HC zinc finger
DUF3499 (PF12005, IPR021888): Protein of unknown function (DUF3499)
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
59 MAGEB2interactor100MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
60 MAP4oncoprotein41.0000SdiA-regulated (PF06977, IPR009722): SdiA-regulated
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
61 MAPK14oncoprotein60.6002.333Pkinase (PF00069, IPR000719): Protein kinase domain
62 MOV10interactor210.25279.054AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
63 MRPS22interactor50.9000.100MRP-S22 (PF10245, IPR019374): Mitochondrial 28S ribosomal protein S22
64 MRPS27interactor80.6073.098MRP-S27 (PF10037, IPR019266): Mitochondrial 28S ribosomal protein S27
65 NCLprotein found in more fusions140.52614.835DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Myc_N (PF01056, IPR012682): Myc amino-terminal region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
YL1 (PF05764, IPR008895): YL1 nuclear protein
Limkain-b1 (PF11608, IPR024582): Limkain b1
66 NOP2interactor140.48419.307BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II)
Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F
P120R (PF08062, IPR012586): P120R (NUC006) repeat
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477)
FAM176 (PF14851): FAM176 family
Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF
67 NTRK1oncoprotein730.1471385.496I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
68 NUDCinteractor80.5713.248CS (PF04969, IPR007052): CS domain
D5_N (PF08706, IPR014818, SM00885): D5 N terminal like
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Nudc_N (PF14050, IPR025934): N-terminal conserved domain of Nudc.
NuDC (PF16273, IPR032572): Nuclear distribution C domain
69 NXF1interactor300.150189.034NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
70 PARK2suppressor270.240137.045IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
71 PARP1suppressor140.47415.373BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain
PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain
WGR (PF05406, IPR008893, SM00773): WGR domain
zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
72 PLS3interactor50.7000.568CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EF-hand_5 (PF13202, IPR002048): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
73 POLDIP3interactor40.5000.508RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
74 PRKDCprotein found in more fusions180.47131.847FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
75 PRSS3interactor100Trypsin (PF00089, IPR001254, SM00020): Trypsin
76 PSME3protein found in more fusions70.5333.467PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit
PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit
77 PWP2interactor30.6670.400Utp12 (PF04003, IPR007148): Dip2/Utp12 Family
Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
78 RACK1suppressor90.6432.317WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
79 RANoncoprotein80.5364.671Ras (PF00071, IPR001806, SM00173): Ras family
80 RBM39oncoprotein150.53315.446RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
81 RBMXsuppressor100.7221.194RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
82 RBX1oncoprotein100.44412.733zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
83 RCC1interactor60.4672.661RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
84 RCC2oncoprotein40.6670.440RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
85 RESToncoprotein21.0000CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Presenilin (PF01080, IPR001108): Presenilin
RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DNA_RNApol_7kD (PF03604, IPR006591, SM00659): DNA directed RNA polymerase, 7 kDa subunit
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
SLBP_RNA_bind (PF15247, IPR029344): Histone RNA hairpin-binding protein RNA-binding domain
86 RFC3interactor80.8570.753CHB_HEX (PF03173, IPR004866, SM01081): Putative carbohydrate binding domain
DNA_pol3_delta (PF06144, IPR010372): DNA polymerase III, delta subunit
Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
DNA_pol3_delta2 (PF13177): DNA polymerase III, delta subunit
87 RFC4interactor120.6368.447AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
Rad17 (PF03215): Rad17 cell cycle checkpoint protein
Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
AAA_assoc_2 (PF16193, IPR032423): AAA C-terminal domain
88 RFC5interactor80.8570.753AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
Rad17 (PF03215): Rad17 cell cycle checkpoint protein
Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
AAA_assoc_2 (PF16193, IPR032423): AAA C-terminal domain
89 RPA1suppressor290.352108.202Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
90 RPP38interactor21.0000Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
91 RUVBL1oncoprotein150.42919.601TIP49 (PF06068, IPR010339): TIP49 C-terminus
92 SH2D4Ainteractor21.0000Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
SH2 (PF00017, IPR000980, SM00252): SH2 domain
DUF2039 (PF10217, IPR019351): Uncharacterized conserved protein (DUF2039)
93 SKP1oncoprotein110.45518.386Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain
Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
94 SLC25A3interactor70.4762.830Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
95 SLC25A5interactor110.52712.093Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
96 SMARCA5interactor90.7144.753HAND (PF09110, IPR015194): HAND
SLIDE (PF09111, IPR015195): SLIDE
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DBINO (PF13892, IPR020838): DNA-binding domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
97 SNRPD1interactor140.53821.310API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
LSM (PF01423, IPR001163): LSM domain
98 SNRPFinteractor30.6670.286LSM (PF01423, IPR001163): LSM domain
99 SPANXN3interactor21.0000SPAN-X (PF07458, IPR010007): Sperm protein associated with nucleus, mapped to X chromosome
100 SRP72interactor51.0000BTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain
SRP72 (PF08492, IPR013699): SRP72 RNA-binding domain
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat
101 SRSF2oncoprotein150.52720.469RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
Transformer (PF06495, IPR010519): Fruit fly transformer protein
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
102 SRSF3oncoprotein150.53315.701DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
103 SRSF5interactor150.45733.470DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
104 SRSF7interactor190.54426.405RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
zf-CCHC (PF00098, IPR001878): Zinc knuckle
105 SSBinteractor70.5712.519HMA (PF00403, IPR006121): Heavy-metal-associated domain
La (PF05383, IPR006630, SM00715): La domain
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_3 (PF08777, IPR014886): RNA binding motif
106 SSR1interactor40.8330.074TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
107 SSRP1interactor50.9000.182Rtt106 (PF08512, IPR013719): Histone chaperone Rttp106-like
SSrecog (PF03531, IPR024954): Structure-specific recognition protein (SSRP1)
YABBY (PF04690, IPR006780): YABBY protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
DUF3987 (PF13148, IPR025048): Protein of unknown function (DUF3987)
CAML (PF14963, IPR016719): Calcium signal-modulating cyclophilin ligand
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
Coilin_N (PF15862, IPR031722): Coilin N-terminus
108 STAU1protein found in more fusions330.282156.032dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
109 THOC3interactor21.0000eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
110 TOP1oncoprotein200.43744.245DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core
Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment
MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
TonB_N (PF16031): TonB N-terminal region
111 TRMT10Cinteractor21.0000tRNA_m1G_MT (PF01746, IPR016009): tRNA (Guanine-1)-methyltransferase
PPR_2 (PF13041, IPR002885): PPR repeat family
112 U2AF2protein found in more fusions340.350131.560RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
113 UBA52interactor50.6001.987Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
114 UBE2D2oncoprotein50.6670.900UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
115 UBR7interactor100PHD (PF00628, IPR019787, SM00249): PHD-finger
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
116 WDR36interactor50.6002.182Utp21 (PF04192, IPR007319): Utp21 specific WD40 associated putative domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
117 WDR5interactor60.4003.934WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
118 ZC3HAV1interactor30.6670.118PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
WWE (PF02825, IPR004170, SM00678): WWE domain
119 ZRANB2interactor70.3817.011RRN3 (PF05327, IPR007991): RNA polymerase I specific transcription initiation factor RRN3
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ASUNinteractorDUF2151 (PF10221, IPR019355): Cell cycle and development regulator
2 BRIX1interactorBrix (PF04427, IPR007109, SM00879): Brix domain
3 C7orf26interactorDUF4507 (PF14964, IPR027844): Domain of unknown function (DUF4507)
4 C7orf50interactorDUF2373 (PF10180, IPR019327): Uncharacterised conserved protein (DUF2373)
5 C8orf33interactorDUF4615 (PF15393, IPR029274): Domain of unknown function (DUF4615)
6 CBX3interactorChromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
7 DIMT1interactorRrnaAD (PF00398, IPR001737, SM00650): Ribosomal RNA adenine dimethylase
8 DRG1interactorMMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
TGS (PF02824, IPR004095): TGS domain
MMR_HSR1_Xtn (PF16897, IPR031662): C-terminal region of MMR_HSR1 domain
9 EBNA1BP2interactorEbp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2
10 EEF2interactorEFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
11 EIF2S1interactorEIF_2_alpha (PF07541, IPR011488): Eukaryotic translation initiation factor 2 alpha subunit
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
12 EIF2S2interactorDUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP)
eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5
Cytochrom_c3_2 (PF14537): Cytochrome c3
13 EIF2S3interactoreIF2_C (PF09173, IPR015256): Initiation factor eIF2 gamma, C terminal
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
14 EMDinteractorLEM (PF03020, IPR003887, SM00540): LEM domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
15 EXOSC10interactorDNA_pol_A_exo1 (PF01612, IPR002562, SM00474): 3'-5' exonuclease
HRDC (PF00570, IPR002121, SM00341): HRDC domain
PMC2NT (PF08066, IPR012588): PMC2NT (NUC016) domain
Sec62 (PF03839, IPR004728): Translocation protein Sec62
16 EXOSC2interactorEXOSC1 (PF10447, IPR019495): Exosome component EXOSC1/CSL4
ECR1_N (PF14382, IPR025721): Exosome complex exonuclease RRP4 N-terminal region
KH_6 (PF15985, IPR004088): KH domain
17 EXOSC3interactorKH_6 (PF15985, IPR004088): KH domain
18 EXOSC6interactorRNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
19 FARSBinteractorB3_4 (PF03483, IPR005146, SM00873): B3/4 domain
B5 (PF03484, IPR005147, SM00874): tRNA synthetase B5 domain
20 FBLinteractorFibrillarin (PF01269, IPR000692): Fibrillarin
21 FBXW2parental proteinWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
22 GRWD1interactorVoldacs (PF03517): Regulator of volume decrease after cellular swelling
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
23 H1F0interactorOAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Hid1 (PF12722): High-temperature-induced dauer-formation protein
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
24 H1FXinteractorIGPS (PF00218, IPR013798): Indole-3-glycerol phosphate synthase
25 H2AFYinteractorDUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Macro (PF01661, IPR002589, SM00506): Macro domain
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
26 H2AFY2interactorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Macro (PF01661, IPR002589, SM00506): Macro domain
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
27 HDAC1suppressorFSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
28 HDAC2suppressorHist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
29 HDGFparental proteinPWWP (PF00855, IPR000313, SM00293): PWWP domain
30 HIST1H1ConcoproteinAmelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin)
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
31 HIST1H1DinteractorStm1_N (PF09598, IPR019084): Stm1
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
32 HIST1H1EinteractorLinker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
33 HIST1H2BCinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
34 HIST1H2BDinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
35 HIST1H2BEinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
36 HIST1H2BFinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
37 HIST1H2BGoncoproteinHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
38 HIST1H2BIinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
39 HIST1H2BKinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
40 HIST1H3AinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
41 HIST1H3BoncoproteinHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
42 HIST1H3CinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
43 HIST1H3DinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
44 HIST1H3EinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
45 HIST1H3FinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
46 HIST1H3GinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
47 HIST1H3HinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
48 HIST1H3IinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
49 HIST1H3JinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
50 HIST1H4AinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
51 HIST1H4BinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
52 HIST1H4CinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
53 HIST1H4DinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
54 HIST1H4EinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
55 HIST1H4FinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
56 HIST1H4HinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
57 HIST1H4IoncoproteinCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
58 HIST1H4JinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
59 HIST1H4KinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
60 HIST1H4LinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
61 HIST2H2BEinteractorHistone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
62 HIST2H4AinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
63 HIST2H4BinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
64 HIST4H4interactorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
65 HMGA2oncoproteinAT_hook (PF02178, IPR017956, SM00384): AT hook motif
DUF1639 (PF07797, IPR012438): Protein of unknown function (DUF1639)
66 HMGN1interactorHMG14_17 (PF01101, IPR000079, SM00527): HMG14 and HMG17
67 HP1BP3interactorRXT2_N (PF08595, IPR013904): RXT2-like, N-terminal
SDA1 (PF05285, IPR007949): SDA1
YL1 (PF05764, IPR008895): YL1 nuclear protein
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
68 INTS10interactorNA
69 KAT5suppressorMOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
70 MCTS1interactorDUF1947 (PF09183, IPR015266): Domain of unknown function (DUF1947)
PUA (PF01472, IPR002478, SM00359): PUA domain
71 MPGinteractorPur_DNA_glyco (PF02245, IPR003180): Methylpurine-DNA glycosylase (MPG)
72 MRTO4interactorGlu_syn_central (PF04898, IPR006982): Glutamate synthase central domain
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
73 MSH6oncoproteinMutS_I (PF01624, IPR007695): MutS domain I
MutS_II (PF05188, IPR007860): MutS domain II
PWWP (PF00855, IPR000313, SM00293): PWWP domain
MutS_V (PF00488, IPR000432, SM00534): MutS domain V
MutS_III (PF05192, IPR007696, SM00533): MutS domain III
UPF0524 (PF15823, IPR029670): UPF0524 of C3orf70
74 MYBBP1AsuppressorDNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal
75 NACAoncoproteinNAC (PF01849, IPR002715): NAC domain
RNA_pol_Rpo13 (PF12136, IPR021985): RNA polymerase Rpo13 subunit HTH domain
CitT (PF12431, IPR028141): Transcriptional regulator
76 OLA1interactorRoc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
YchF-GTPase_C (PF06071, IPR013029): Protein of unknown function (DUF933)
77 PGAM5interactorHis_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
78 PHF6suppressorzf-HC5HC2H (PF13771): PHD-like zinc-binding domain
YqfQ (PF14181, IPR025571): YqfQ-like protein
79 POLRMTinteractorDUF615 (PF04751, IPR006839): Protein of unknown function (DUF615)
PSD2 (PF07624, IPR011478): Protein of unknown function (DUF1585)
RNA_pol (PF00940, IPR002092): DNA-dependent RNA polymerase
PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain
RPOL_N (PF14700, IPR029262): DNA-directed RNA polymerase N-terminal
80 PRMT5interactorPRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
81 PSIP1oncoproteinAT_hook (PF02178, IPR017956, SM00384): AT hook motif
BEX (PF04538, IPR021156): Brain expressed X-linked like family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
PGA2 (PF07543, IPR011431): Protein trafficking PGA2
PWWP (PF00855, IPR000313, SM00293): PWWP domain
LEDGF (PF11467, IPR021567): Lens epithelium-derived growth factor (LEDGF)
TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2
82 RBBP4oncoproteineIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
83 RCL1interactorRTC (PF01137, IPR023797): RNA 3'-terminal phosphate cyclase
84 RFC1interactorAAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family
Nexin_C (PF08628, IPR013937): Sorting nexin C terminal
RFC1 (PF08519, IPR013725): Replication factor RFC1 C terminal domain
DUF2316 (PF10078, IPR018757): Uncharacterized protein conserved in bacteria (DUF2316)
85 RNA18S5interactorNA
86 RNA28S5interactorNA
87 RPL10suppressorRibosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
88 RPL17interactorRibosomal_L22 (PF00237, IPR001063): Ribosomal protein L22p/L17e
89 RPL19interactorDUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e
90 RPL22oncoproteinRibosomal_L22e (PF01776, IPR002671): Ribosomal L22e protein family
91 RPL32interactorRibosomal_L32e (PF01655, IPR001515): Ribosomal protein L32
92 RPL34interactorRedoxin (PF08534, IPR013740): Redoxin
Ribosomal_L34e (PF01199, IPR008195): Ribosomal protein L34e
93 RPL35interactorRibosomal_L29 (PF00831, IPR001854): Ribosomal L29 protein
XFP_N (PF09364, IPR018970): XFP N-terminal domain
94 RPL35AinteractorRibosomal_L35Ae (PF01247, IPR001780): Ribosomal protein L35Ae
95 RPS11interactorRibosomal_S17 (PF00366, IPR000266): Ribosomal protein S17
Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
96 RPS15AinteractorRibosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
97 RPS23interactorRibosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23
98 RRP1BinteractorNop52 (PF05997, IPR010301): Nucleolar protein,Nop52
99 RSL1D1interactorRibosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
100 SMC3oncoproteinSMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
101 SRP68interactorRhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB
SRP68 (PF16969, IPR026258): RNA-binding signal recognition particle 68
102 SRPK1interactorFYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pkinase (PF00069, IPR000719): Protein kinase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
103 SRSF1interactorCorona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
104 SUB1interactorDehydrin (PF00257, IPR000167): Dehydrin
PC4 (PF02229, IPR003173): Transcriptional Coactivator p15 (PC4)
105 SUPT16HinteractorNop14 (PF04147, IPR007276): Nop14-like family
Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
Rtt106 (PF08512, IPR013719): Histone chaperone Rttp106-like
SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68)
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
FACT-Spt16_Nlob (PF14826, IPR029148): FACT complex subunit SPT16 N-terminal lobe domain
106 TMPOinteractorLEM (PF03020, IPR003887, SM00540): LEM domain
Thymopoietin (PF08198, IPR013146): Thymopoietin protein
LAP2alpha (PF11560, IPR021623): Lamina-associated polypeptide 2 alpha
107 TSR1interactorAARP2CN (PF08142, IPR012948, SM00785): AARP2CN (NUC121) domain
RIBIOP_C (PF04950, IPR007034): 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
NUSAP (PF16006, IPR026756): Nucleolar and spindle-associated protein
108 U2AF1oncoproteinDUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509)
KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
109 VWA9interactorVWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
110 XBP1interactorDUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
DUF2630 (PF10944, IPR020311): Protein of unknown function (DUF2630)
111 XRCC5suppressorKu (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
112 XRCC6oncoproteinKu (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain

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