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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BF809109 is the fusion of parental proteins UBQLN1 (from a repository: Mon Dec 5 10:05:50 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)209
The number (and %) of the onco-proteins55 (26.32 %)
The number (and %) of the tumor suppressors12 (5.74 %)
Total number of binary PPIs (saturation %)899 (4.14 %)
The number (and %) of affected PPIs208 (23.14 %)
The number of possible different fusions27
PPI diameter2
PPI radius1
The average degree of PPI8.057
Assortativity coefficient-0.3715
The network average Clustering coefficient0.517
The number (and %) of a zero Clustering coefficients47 (22.49 %)
The number (and %) of a zero Betweenness Centrality102 (48.80 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: UBQLN1 All fusions
: BF809109;
Proteins found in more fusions PSMC2 (see 1 fusions); APP (see 4 fusions); MCM7 (see 2 fusions); VCP (see 4 fusions); EPS15 (see 1 fusions); UBE2C (see 1 fusions); TICAM1 (see 1 fusions); GPX3 (see 5 fusions); PDCD6 (see 1 fusions); VPS26A (see 1 fusions); MAP3K1 (see 1 fusions); TNFRSF1A (see 2 fusions); UBE2D2 (see 2 fusions); AHCYL1 (see 3 fusions); RARA (see 4 fusions); UBQLN2 (see 2 fusions); PSMA7 (see 2 fusions); HTT (see 1 fusions); MIEF1 (see 1 fusions); EP300 (see 1 fusions); NDE1 (see 3 fusions); UBC (see 1 fusions); MTOR (see 1 fusions); PRPF40A (see 2 fusions); RASSF5 (see 2 fusions); GAPDH (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BF809109chimera2090.02935953.580XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
2 ABCC2interactor100ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
DUF805 (PF05656, IPR008523): Protein of unknown function (DUF805)
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
3 ACOT7interactor31.00004HBT (PF03061, IPR006683): Thioesterase superfamily
NINJA_B (PF16136, IPR032310): Putative nuclear localisation signal
4 ADRM1interactor170.7359.221Proteasom_Rpn13 (PF04683, IPR006773): Proteasome complex subunit Rpn13 ubiquitin receptor
GET2 (PF08690, IPR028143): GET complex subunit GET2
RPN13_C (PF16550, IPR032368): UCH-binding domain
5 AGPAT5interactor100Acyltransferase (PF01553, IPR002123, SM00563): Acyltransferase
Acyltransf_C (PF16076, IPR032098): Acyltransferase C-terminus
6 AGR2interactor30.6670.182Thioredoxin_7 (PF13899): Thioredoxin-like
7 AGR3interactor100Thioredoxin_7 (PF13899): Thioredoxin-like
8 AHCYL1suppressor230.35171.629AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
DUF515 (PF04415, IPR007509): Protein of unknown function (DUF515)
Big_3_5 (PF16640, IPR032109): Bacterial Ig-like domain (group 3)
9 APPprotein found in more fusions360.096456.879APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
10 ASNSoncoprotein40.6671.125Asn_synthase (PF00733, IPR001962): Asparagine synthase
GATase_7 (PF13537, IPR000583): Glutamine amidotransferase domain
11 ATP6V1B2interactor100.46712.045ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
DUF2481 (PF10654, IPR018916): Protein of unknown function (DUF2481)
12 ATP6V1Hinteractor40.6671.400V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
13 ATXN3interactor110.44411.864Josephin (PF02099, IPR006155): Josephin
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
14 BCL2L10interactor200Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
15 BPIFA1interactor31.0000LBP_BPI_CETP (PF01273, IPR017942, SM00328): LBP / BPI / CETP family, N-terminal domain
16 C12orf10interactor21.0000UPF0160 (PF03690, IPR003226): Uncharacterised protein family (UPF0160)
17 C1QAoncoprotein30.6670.286C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
18 C1QTNF2interactor21.0000C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
19 CALUinteractor50.9000.167EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
20 CCL7oncoprotein200IL8 (PF00048, IPR001811, SM00199): Small cytokines (intecrine/chemokine), interleukin-8 like
DUF4725 (PF15854, IPR031713): Domain of unknown function (DUF4725)
21 CD3Dinteractor21.0000DAP10 (PF07213, IPR009861): DAP10 membrane protein
ITAM (PF02189, IPR003110, SM00077): Immunoreceptor tyrosine-based activation motif
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
22 CD99interactor31.0000CD99L2 (PF12301, IPR022078): CD99 antigen like protein 2
23 CD99L2interactor21.0000CD99L2 (PF12301, IPR022078): CD99 antigen like protein 2
24 CHGBinteractor21.0000Granin (PF01271, IPR001990): Granin (chromogranin or secretogranin)
25 CLNS1Ainteractor80.4644.974Voldacs (PF03517): Regulator of volume decrease after cellular swelling
26 COL10A1interactor100C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
27 COL1A2oncoprotein100COLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
28 COLGALT2interactor21.0000Aminotran_4 (PF01063, IPR001544): Amino-transferase class IV
Glyco_transf_25 (PF01755, IPR002654): Glycosyltransferase family 25 (LPS biosynthesis protein)
Glyco_tranf_2_4 (PF13704): Glycosyl transferase family 2
29 COMTD1interactor30.6670.667FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
30 CSTF2interactor50.8000.848RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal
CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
31 CSTF2Tinteractor41.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal
CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
32 CTAG1Binteractor100Pcc1 (PF09341, IPR015419): Transcription factor Pcc1
33 CTAG2interactor100Pcc1 (PF09341, IPR015419): Transcription factor Pcc1
34 CYB5R1interactor31.0000FAD_binding_6 (PF00970, IPR008333): Oxidoreductase FAD-binding domain
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
35 DCTPP1interactor60.6002.867MazG-like (PF12643, IPR025984): MazG-like family
36 DEFA6interactor21.0000Defensin_1 (PF00323, IPR006081): Mammalian defensin
Defensin_propep (PF00879, IPR002366): Defensin propeptide
37 DNAJB2interactor70.4296.123DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
38 EFEMP2interactor21.0000EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Adipogenin (PF15202, IPR027938): Adipogenin
39 EP300oncoprotein80.4767.200Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
40 EPS15oncoprotein120.45512.684Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
41 EPS15L1oncoprotein21.0000CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
42 ERP27interactor21.0000Thioredoxin_6 (PF13848): Thioredoxin-like domain
43 ETNK1interactor100Choline_kinase (PF01633): Choline/ethanolamine kinase
RskA (PF10099, IPR018764): Anti-sigma-K factor rskA
44 F8interactor100Cu-oxidase (PF00394, IPR001117): Multicopper oxidase
Cu-oxidase_2 (PF07731, IPR011706): Multicopper oxidase
Cu-oxidase_3 (PF07732, IPR011707): Multicopper oxidase
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
45 FAM127Ainteractor21.0000DUF4939 (PF16297, IPR032549): Domain of unknown function (DUF4939)
46 FAM127Binteractor21.0000DUF4939 (PF16297, IPR032549): Domain of unknown function (DUF4939)
47 FAM127Cinteractor100DUF4939 (PF16297, IPR032549): Domain of unknown function (DUF4939)
48 FAM189A2interactor50.4002.733CD20 (PF04103, IPR007237): CD20-like family
49 FASsuppressor50.5002.667Death (PF00531, IPR000488, SM00005): Death domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
Stn1_C (PF12659, IPR024263): Telomere capping C-terminal wHTH
50 FBXO25suppressor100.35614.887Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
51 FCGR2Ainteractor21.0000DUF3827 (PF12877, IPR024606): Domain of unknown function (DUF3827)
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator
52 FGF7oncoprotein100FGF (PF00167, IPR002209, SM00442): Fibroblast growth factor
53 FKBP2interactor31.0000FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
54 FN1oncoprotein200.20098.237fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
55 FZD7interactor21.0000Frizzled (PF01534, IPR000539): Frizzled/Smoothened family membrane region
Fz (PF01392, IPR020067, SM00063): Fz domain
56 GABRA1interactor21.0000Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
57 GABRA2interactor100Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
58 GABRA3interactor100Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
59 GABRA6interactor100Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
60 GABRB1interactor100Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
61 GABRB2interactor100Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
62 GABRB3interactor100Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
63 GABRDinteractor21.0000Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
PsbY (PF06298, IPR009388): Photosystem II protein Y (PsbY)
64 GAPDHoncoprotein140.25642.651Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
65 GHRLoncoprotein100Motilin_assoc (PF04643, IPR006737): Motilin/ghrelin-associated peptide
Motilin_ghrelin (PF04644, IPR006738): Motilin/ghrelin
66 GIT2interactor200ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
Sen15 (PF09631, IPR018593): Sen15 protein
GIT_SHD (PF08518, IPR013724, SM00555): Spa2 homology domain (SHD) of GIT
GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
DUF4482 (PF14818, IPR027882): Domain of unknown function (DUF4482)
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
67 GKAP1interactor41.0000CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
68 GNB1interactor30.6670.500Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
69 GNPDA1interactor40.8330.667Glucosamine_iso (PF01182, IPR006148): Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
70 GPX3suppressor200GSHPx (PF00255, IPR000889): Glutathione peroxidase
71 GRM2interactor1007tm_3 (PF00003, IPR017978): 7 transmembrane sweet-taste receptor of 3 GCPR
ANF_receptor (PF01094, IPR001828): Receptor family ligand binding region
NCD3G (PF07562, IPR011500): Nine Cysteines Domain of family 3 GPCR
72 GYPBinteractor100Glycophorin_A (PF01102, IPR001195): Glycophorin A
Ibs_toxin (PF13956, IPR025881): Toxin Ibs, type I toxin-antitoxin system
73 HERC3interactor90.5568.695RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
74 HERPUD1oncoprotein80.5003.906Neisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
75 HGSinteractor150.30552.432FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
PIEZO (PF15917, IPR031805): Piezo
76 HK2interactor40.5002.125Hexokinase_1 (PF00349, IPR022672): Hexokinase
Hexokinase_2 (PF03727, IPR022673): Hexokinase
77 HSD17B12interactor50.8000.422adh_short (PF00106, IPR002198): short chain dehydrogenase
78 HSPA13interactor31.0000HSP70 (PF00012, IPR013126): Hsp70 protein
79 HSPA1Linteractor70.3338.250HSP70 (PF00012, IPR013126): Hsp70 protein
80 HTTprotein found in more fusions90.42911.567HEAT (PF02985, IPR000357): HEAT repeat
SPX (PF03105, IPR004331): SPX domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF3652 (PF12372, IPR024613): Huntingtin protein region
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
81 HYPKinteractor30.6670.500Utp11 (PF03998, IPR007144): Utp11 protein
82 IGLC1interactor21.0000C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
83 IGLV2-14interactor100V-set (PF07686, IPR013106): Immunoglobulin V-set domain
84 IL6SToncoprotein100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
IL6Ra-bind (PF09240, IPR015321): Interleukin-6 receptor alpha chain, binding
Lep_receptor_Ig (PF06328, IPR010457): Ig-like C2-type domain
Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
85 INSIG2interactor90.6393.569INSIG (PF07281, IPR025929): Insulin-induced protein (INSIG)
86 ITPRIPL1interactor21.0000Mab-21 (PF03281, IPR024810): Mab-21 protein
87 KLHL42interactor31.0000BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
Kelch_6 (PF13964): Kelch motif
88 LITAFsuppressor31.0000zf-LITAF-like (PF10601, IPR006629, SM00714): LITAF-like zinc ribbon domain
DUF3824 (PF12868, IPR024436): Domain of unknwon function (DUF3824)
89 MANBALinteractor100UPF0239 (PF06783, IPR009621): Uncharacterised protein family (UPF0239)
90 MAP1LC3Ainteractor90.47211.784Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
91 MAP3K1oncoprotein130.31820.868zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Pkinase (PF00069, IPR000719): Protein kinase domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
92 MCM7protein found in more fusions100.38912.206MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
93 MIEF1protein found in more fusions200Mab-21 (PF03281, IPR024810): Mab-21 protein
94 MIEF2interactor21.0000Mab-21 (PF03281, IPR024810): Mab-21 protein
95 MLLT6oncoprotein40.5001.098DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
PHD_2 (PF13831): PHD-finger
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
SOBP (PF15279, IPR026092): Sine oculis-binding protein
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
96 MTHFD1interactor60.5334.289FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase
THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
97 MTORoncoprotein50.5001.667DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104)
EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain
V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
TPR_19 (PF14559): Tetratricopeptide repeat
98 NAXDinteractor21.0000Carb_kinase (PF01256, IPR000631): Carbohydrate kinase
GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
99 NBL1oncoprotein100DAN (PF03045, IPR004133): DAN domain
DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
100 NDE1protein found in more fusions200NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
101 NGLY1interactor50.6000.936PUB (PF09409, IPR018997): PUB domain
Rad4 (PF03835, IPR018325): Rad4 transglutaminase-like domain
PAW (PF04721, IPR006588, SM00613): PNGase C-terminal domain, mannose-binding module PAW
Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
102 NME3oncoprotein30.6670.182NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
103 NPPAinteractor21.0000ANP (PF00212, IPR000663, SM00183): Atrial natriuretic peptide
104 NPYoncoprotein100Hormone_3 (PF00159, IPR001955): Pancreatic hormone peptide
105 NTRK1oncoprotein470.150669.532I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
106 NUBP1interactor40.6672.000DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258
ParA (PF10609, IPR019591): NUBPL iron-transfer P-loop NTPase
107 NUP58interactor31.0000Nucleoporin_FG2 (PF15967): Nucleoporin FG repeated region
108 ORAI1interactor100Orai-1 (PF07856, IPR012446): Mediator of CRAC channel activity
109 P4HBinteractor120.41818.709Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
110 PARVAoncoprotein40.6671.333CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
111 PBXIP1interactor40.5001.792DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
MscS_porin (PF12795, IPR024393): Mechanosensitive ion channel porin domain
112 PDCD6oncoprotein60.7002.667EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
113 PIK3IP1interactor100Kringle (PF00051, IPR000001): Kringle domain
Ost4 (PF10215, IPR018943): Oligosaccaryltransferase
114 PLA2G16suppressor21.0000LRAT (PF04970, IPR007053): Lecithin retinol acyltransferase
115 PNMA1oncoprotein50.6002.667PNMA (PF14893, IPR026523): PNMA
116 PPIBinteractor100.37820.642Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
117 PPICinteractor21.0000Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
118 PRAP1interactor1003HBOH (PF10605, IPR016582): 3HB-oligomer hydrolase (3HBOH)
PRAP (PF15314, IPR027922): Proline-rich acidic protein 1, pregnancy-specific uterine
119 PRB1interactor100Pro-rich (PF15240, IPR026086): Proline-rich
120 PRPF40Aprotein found in more fusions90.5366.725FF (PF01846, IPR002713, SM00441): FF domain
MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain
Transformer (PF06495, IPR010519): Fruit fly transformer protein
WW (PF00397, IPR001202, SM00456): WW domain
YqzE (PF14038, IPR025622): YqzE-like protein
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus
SOBP (PF15279, IPR026092): Sine oculis-binding protein
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
121 PSEN1oncoprotein100.44412.595Presenilin (PF01080, IPR001108): Presenilin
LRRC37AB_C (PF14914, IPR029423): LRRC37A/B like protein 1 C-terminal domain
122 PSEN2oncoprotein41.0000Herpes_LMP1 (PF05297, IPR007961): Herpesvirus latent membrane protein 1 (LMP1)
Presenilin (PF01080, IPR001108): Presenilin
123 PSMA5oncoprotein200.55830.577Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
124 PSMA6interactor210.56242.898Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
125 PSMA7protein found in more fusions210.60525.045Proteasome (PF00227, IPR001353): Proteasome subunit
Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
126 PSMC2protein found in more fusions240.53445.447AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
127 PSMD14interactor170.7876.476JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
128 PSMD2oncoprotein210.48662.256PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
THAP (PF05485, IPR006612, SM00980): THAP domain
HEAT_2 (PF13646): HEAT repeats
129 PSMD3interactor160.72513.415Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
130 PSMD4interactor280.43491.822UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
131 PSMD6interactor160.68316.938RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7
PCI (PF01399, IPR000717, SM00088): PCI domain
132 PTNoncoprotein50.6671.000PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain
PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
133 PYM1interactor31.0000CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD)
Mago-bind (PF09282, IPR015362): Mago binding
AAA_23 (PF13476): AAA domain
134 RAD23Aoncoprotein290.368136.973UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
135 RAD23Bsuppressor160.60817.134K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
136 RAP1GDS1oncoprotein50.7002.000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
WAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin
Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
HEAT_2 (PF13646): HEAT repeats
Nitr_red_bet_C (PF14711, IPR029263): Respiratory nitrate reductase beta C-terminal
SIL1 (PF16782, IPR031884): Nucleotide exchange factor SIL1
137 RARAoncoprotein70.3336.633zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
138 RASSF5suppressor31.0000RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
139 RBMS1interactor21.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
140 RELAoncoprotein130.45520.377DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
141 RIC8Ainteractor30.6670.125PUL (PF08324, IPR013535): PUL domain
Ric8 (PF10165, IPR019318): Guanine nucleotide exchange factor synembryn
142 RNF185interactor170.40832.982zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
143 RNF208interactor21.0000GcpE (PF04551, IPR004588): GcpE protein
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
144 RPN1oncoprotein120.37919.547Ribophorin_I (PF04597, IPR007676): Ribophorin I
CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
145 RSRC2interactor50.5001.822Pap_E4 (PF02711, IPR003861): E4 protein
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
SMAP (PF15477, IPR028124): Small acidic protein family
146 SCG2interactor21.0000Granin (PF01271, IPR001990): Granin (chromogranin or secretogranin)
147 SCG5interactor21.0000Secretogranin_V (PF05281, IPR007945): Neuroendocrine protein 7B2 precursor (Secretogranin V)
148 SCMH1interactor31.0000MBT (PF02820, IPR004092, SM00561): mbt repeat
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SLED (PF12140, IPR021987): SLED domain
RBR (PF17208): RNA binding Region
149 SERPINE1interactor31.0000Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
150 SERPINI2suppressor21.0000Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
151 SFXN1interactor31.0000Mtc (PF03820, IPR004686): Tricarboxylate carrier
152 SHFM1interactor190.62022.847CLLAC (PF15675, IPR031379): CLLAC-motif containing domain
153 SIL1interactor21.0000Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
HEAT (PF02985, IPR000357): HEAT repeat
RTTN_N (PF14726, IPR029249): Rotatin, an armadillo repeat protein, centriole functioning
DUF4704 (PF15787, IPR031570): Domain of unknown function (DUF4704)
154 SLC29A2interactor100Nucleoside_tran (PF01733, IPR002259): Nucleoside transporter
DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
155 SMAD9interactor50.5002.667MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
156 SMR3Binteractor100PROL5-SMR (PF15621, IPR026288): Proline-rich submaxillary gland androgen-regulated family
157 SNRNP70interactor100.28922.384RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
158 SPARCsuppressor100FOLN (PF09289, IPR015369, SM00274): Follistatin/Osteonectin-like EGF domain
Kazal_1 (PF00050, IPR002350): Kazal-type serine protease inhibitor domain
SPARC_Ca_bdg (PF10591, IPR019577): Secreted protein acidic and rich in cysteine Ca binding region
159 SRGNinteractor21.0000Serglycin (PF04360, IPR007455): Serglycin
160 SSSCA1interactor190.44431.305Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
161 STAM2interactor120.40925.202GAT (PF03127, IPR004152): GAT domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
162 STMN1interactor70.3816.655Stathmin (PF00836, IPR000956): Stathmin family
163 STMN3interactor100Stathmin (PF00836, IPR000956): Stathmin family
164 TARDBPinteractor120.38219.830RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
165 TFF1oncoprotein31.0000Trefoil (PF00088, IPR000519, SM00018): Trefoil (P-type) domain
166 TICAM1protein found in more fusions31.0000Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
RHIM (PF12721, IPR025735): RIP homotypic interaction motif
TIR_2 (PF13676, IPR000157): TIR domain
167 TLR4interactor30.6671.000LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
TIR (PF01582, IPR000157, SM00255): TIR domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
LRR_9 (PF14580): Leucine-rich repeat
168 TMCO6interactor21.0000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
KorB (PF08535, IPR013741): KorB domain
HEAT_EZ (PF13513): HEAT-like repeat
169 TMEM31interactor100DUF912 (PF06024, IPR009261): Nucleopolyhedrovirus protein of unknown function (DUF912)
DUF2207 (PF09972, IPR018702): Predicted membrane protein (DUF2207)
DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519)
170 TMEM37interactor100TMEM37 (PF15108, IPR029372): Voltage-dependent calcium channel gamma-like subunit protein family
171 TMUB2interactor100SKG6 (PF08693, IPR014805): Transmembrane alpha-helix domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
172 TNFRSF1Aoncoprotein50.5003.000Death (PF00531, IPR000488, SM00005): Death domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
173 TNFRSF1Boncoprotein31.0000TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
174 TREX1interactor100RNase_T (PF00929, IPR013520): Exonuclease
DUF2733 (PF10813, IPR024360): Protein of unknown function (DUF2733)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
175 TRIAP1oncoprotein100UPF0203 (PF05254, IPR007918): Uncharacterised protein family (UPF0203)
176 TRIM32suppressor100.38915.621NHL (PF01436, IPR001258): NHL repeat
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
177 TXNDC12interactor100Thioredoxin_7 (PF13899): Thioredoxin-like
178 UBBinteractor110.29123.505ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
179 UBCprotein found in more fusions470.221506.417ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
180 UBE2Ainteractor100.6113.721UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
181 UBE2Binteractor130.6066.588UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
182 UBE2Concoprotein200.44448.570UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
183 UBE2D1interactor210.34762.065UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
184 UBE2D2oncoprotein180.37545.537UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
185 UBE2V1interactor150.46724.431UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
186 UBE3Aoncoprotein200.38661.665HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
187 UBE4Bsuppressor210.42147.095DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
Ufd2P_core (PF10408, IPR019474): Ubiquitin elongating factor core
U-box (PF04564, IPR003613, SM00504): U-box domain
DUF4568 (PF15132, IPR027919): Domain of unknown function (DUF4568)
188 UBL4Ainteractor150.29542.777ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
189 UBL7oncoprotein130.60312.783UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
190 UBQLN2protein found in more fusions330.206271.675Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
SUZ (PF12752, IPR024771): SUZ domain
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
191 UBQLN4interactor660.0651790.347CRF (PF00473, IPR000187, SM00039): Corticotropin-releasing factor family
DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
Arm_2 (PF04826, IPR006911): Armadillo-like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
partial_CstF (PF15861, IPR031721): Partial cleavage stimulation factor domain
192 UBXN1interactor190.39251.566Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
UBX (PF00789, IPR001012, SM00166): UBX domain
193 UBXN4interactor31.0000Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
UBX (PF00789, IPR001012, SM00166): UBX domain
Thioredoxin_7 (PF13899): Thioredoxin-like
194 UCHL3interactor150.50522.465Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
195 UNKinteractor150.35240.126MbeD_MobD (PF04899, IPR006983): MbeD/MobD like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
Torus (PF16131, IPR032297): Torus domain
196 USP34interactor170.58116.981Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUF3517 (PF12030, IPR021905): Domain of unknown function (DUF3517)
197 USP9Xinteractor170.52926.759DUF1722 (PF08349, IPR013560): Protein of unknown function (DUF1722)
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain
198 VCPprotein found in more fusions330.190298.259AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
199 VPS26Aprotein found in more fusions140.29532.500Vps26 (PF03643, IPR005377): Vacuolar protein sorting-associated protein 26
200 VPS4Binteractor80.8211.098AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily)
MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
TIP49 (PF06068, IPR010339): TIP49 C-terminus
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
201 WDFY1interactor100FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
ELYS-bb (PF16687, IPR032040): beta-propeller of ELYS nucleoporin
202 XPO4interactor30.6670.667CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
203 ZFAND2Binteractor70.5713.625UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger
204 ZG16interactor21.0000Jacalin (PF01419, IPR001229, SM00915): Jacalin-like lectin domain
Beta-prism_lec (PF16458, IPR032496): Beta-prism lectin
205 ZG16Binteractor31.0000Jacalin (PF01419, IPR001229, SM00915): Jacalin-like lectin domain
206 ZMYM3interactor30.6670.286NCD3G (PF07562, IPR011500): Nine Cysteines Domain of family 3 GPCR
YHS (PF04945, IPR007029): YHS domain
zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif
DUF3504 (PF12012, IPR021893): Domain of unknown function (DUF3504)
SOBP (PF15279, IPR026092): Sine oculis-binding protein
207 ZMYM4interactor100YHS (PF04945, IPR007029): YHS domain
DUF2116 (PF09889, IPR019216): Uncharacterized protein containing a Zn-ribbon (DUF2116)
zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif
DUF3504 (PF12012, IPR021893): Domain of unknown function (DUF3504)
zinc_ribbon_4 (PF13717): zinc-ribbon domain
YyzF (PF14116, IPR025626): YyzF-like protein
208 ZNF343interactor21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-P11 (PF03854, IPR003224): P-11 zinc finger
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
209 ZRANB2interactor130.51323.277RRN3 (PF05327, IPR007991): RNA polymerase I specific transcription initiation factor RRN3
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 FAM86B3PinteractorNA
2 IGLoncoproteinNA
3 IST1interactorIst1 (PF03398, IPR005061): Regulator of Vps4 activity in the MVB pathway
4 SMIM2interactorNA
5 UBQLN1parental proteinClathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
FAM199X (PF15814, IPR029672): Protein family FAM199X

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