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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BF511918 is the fusion of parental proteins PAK4, ZFP36 (from a repository: Mon Jan 23 06:19:43 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)71
The number (and %) of the onco-proteins26 (36.62 %)
The number (and %) of the tumor suppressors14 (19.72 %)
Total number of binary PPIs (saturation %)294 (11.83 %)
The number (and %) of affected PPIs70 (23.81 %)
The number of possible different fusions16
PPI diameter2
PPI radius1
The average degree of PPI7.352
Assortativity coefficient-0.1565
The network average Clustering coefficient0.523
The number (and %) of a zero Clustering coefficients8 (11.27 %)
The number (and %) of a zero Betweenness Centrality17 (23.94 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: ZFP36,PAK4 All fusions
: BF511918;
Proteins found in more fusions APP (see 4 fusions); YWHAG (see 1 fusions); SH3KBP1 (see 1 fusions); YWHAZ (see 1 fusions); ZDHHC17 (see 2 fusions); VCL (see 2 fusions); HDAC7 (see 1 fusions); SRPK2 (see 1 fusions); NFKB1 (see 2 fusions); RAC1 (see 1 fusions); CDK6 (see 1 fusions); LIMK1 (see 1 fusions); YWHAH (see 2 fusions); NCL (see 3 fusions); SNW1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BF511918chimera700.0793579.346Axin_b-cat_bind (PF08833, IPR014936): Axin beta-catenin binding domain
PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
2 ABL1oncoprotein200.36375.868Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
3 APPprotein found in more fusions160.21968.000APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
4 ARHGEF11interactor30.6670.667CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RGS-like (PF09128, IPR015212): Regulator of G protein signalling-like domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
5 CARMIL1interactor21.0000LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
IL34 (PF15036, IPR020415): Interleukin 34
CARMIL_C (PF16000, IPR031943): CARMIL C-terminus
6 CDC42oncoprotein80.28612.333Ras (PF00071, IPR001806, SM00173): Ras family
7 CDC5Linteractor100.6397.000OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
8 CDK6suppressor60.6003.000Pkinase (PF00069, IPR000719): Protein kinase domain
9 DDX6oncoprotein90.52810.670DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
10 DHX36interactor30.6670.500DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
11 DLSToncoprotein1002-oxoacid_dh (PF00198, IPR001078): 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106)
12 DNAJB1suppressor60.6002.806DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
13 DUSP2oncoprotein100DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
14 EDC4interactor50.9000.286DUF445 (PF04286, IPR007383): Protein of unknown function (DUF445)
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
DUF2756 (PF10956, IPR020158): Protein of unknown function (DUF2756)
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
15 FBXO25suppressor40.5002.333Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
16 GGNBP2suppressor100SPT2 (PF08243, IPR013256, SM00784): SPT2 chromatin protein
TSLP (PF15216, IPR029189): Thymic stromal lymphopoietin
AP3D1 (PF06375): AP-3 complex subunit delta-1
17 HDAC1suppressor60.5003.833FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
18 HDAC3suppressor70.6002.415Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
19 HDAC7protein found in more fusions120.52717.619Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO
20 HECW2interactor50.5002.000C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain
HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
21 HIST1H1Ainteractor40.5002.333Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
22 HSPA4interactor100.37819.758Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
23 ITGB5interactor100EGF_2 (PF07974, IPR013111): EGF-like domain
Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain
PSI_integrin (PF17205): Integrin plexin domain
24 KLHL2interactor200BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
25 KLHL42interactor100BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
Kelch_6 (PF13964): Kelch motif
26 LATS2suppressor51.0000Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
27 LIMK1oncoprotein80.4768.733LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
28 LRRK1interactor41.0000Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
29 MAP3K4suppressor60.4004.733CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pkinase (PF00069, IPR000719): Protein kinase domain
PLU-1 (PF08429, IPR013637): PLU-1-like protein
Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
DUF3958 (PF13125, IPR025014): Protein of unknown function (DUF3958)
30 MAPKAPK2oncoprotein50.8330.667Pkinase (PF00069, IPR000719): Protein kinase domain
31 NAA20interactor21.0000Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
32 NAA25interactor50.5003.508BTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain
NatB_MDM20 (PF09797, IPR019183): N-acetyltransferase B complex (NatB) non catalytic subunit
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
Alkyl_sulf_dimr (PF14863, IPR029228): Alkyl sulfatase dimerisation
33 NCLprotein found in more fusions70.5335.333DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Myc_N (PF01056, IPR012682): Myc amino-terminal region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
YL1 (PF05764, IPR008895): YL1 nuclear protein
Limkain-b1 (PF11608, IPR024582): Limkain b1
34 NFKB1suppressor70.6003.082Death (PF00531, IPR000488, SM00005): Death domain
GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
35 NTRK1oncoprotein290.235230.730I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
36 PAK5interactor40.6670.400PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
37 PAK6interactor50.4004.467PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
38 POT1interactor70.5335.467POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein
39 PPM1Binteractor80.42912.733PP2C (PF00481, IPR001932): Protein phosphatase 2C
PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain
40 PPP2CAsuppressor90.30619.806Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
41 PPP2CBsuppressor31.0000Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
42 PXNoncoprotein50.5004.067LIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
43 RAC1oncoprotein80.28612.333Ras (PF00071, IPR001806, SM00173): Ras family
44 RANoncoprotein41.0000Ras (PF00071, IPR001806, SM00173): Ras family
45 RCC2oncoprotein40.5001.733RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
46 RGS16interactor100RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
47 RHOUinteractor30.6671.000Ras (PF00071, IPR001806, SM00173): Ras family
SLBP_RNA_bind (PF15247, IPR029344): Histone RNA hairpin-binding protein RNA-binding domain
48 RHOVinteractor100Ras (PF00071, IPR001806, SM00173): Ras family
AAA_25 (PF13481): AAA domain
49 SFNsuppressor90.8570.98014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
50 SH3KBP1protein found in more fusions70.3339.000Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein
SH3_9 (PF14604, IPR001452): Variant SH3 domain
51 SH3RF2interactor40.5002.167SH3_2 (PF07653, IPR011511): Variant SH3 domain
TUDOR (PF00567, IPR002999, SM00333): Tudor domain
UPF0547 (PF10571, IPR018886): Uncharacterised protein family UPF0547
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
SH3_9 (PF14604, IPR001452): Variant SH3 domain
52 SNW1protein found in more fusions60.5004.500SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
53 SRPK1interactor60.5334.889FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pkinase (PF00069, IPR000719): Protein kinase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
54 SRPK2oncoprotein100.47213.341DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
55 STK40interactor30.6671.000Pkinase (PF00069, IPR000719): Protein kinase domain
Kinase-like (PF14531, IPR027916): Kinase-like
56 SUPT5Hinteractor40.6671.250KOW (PF00467, IPR005824, SM00739): KOW motif
Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
57 TANKsuppressor40.6671.000DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713)
TBD (PF12845, IPR024581): TBD domain
58 TERF1interactor120.32728.033TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
59 TMEM17interactor21.0000Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
60 TMPRSS11Asuppressor21.0000SEA (PF01390, IPR000082, SM00200): SEA domain
Trypsin (PF00089, IPR001254, SM00020): Trypsin
DUF4179 (PF13786, IPR025436): Domain of unknown function (DUF4179)
61 TRAF2interactor50.5002.667MATH (PF00917, IPR002083, SM00061): MATH domain
Sina (PF03145, IPR018121): Seven in absentia protein family
SlyX (PF04102, IPR007236): SlyX
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
62 VCLoncoprotein110.7566.182Vinculin (PF01044, IPR006077): Vinculin family
63 XPO1interactor180.32075.106CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
64 YWHABinteractor120.6828.91314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
65 YWHAEoncoprotein140.62616.66914-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
66 YWHAGprotein found in more fusions180.52233.57914-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
67 YWHAHprotein found in more fusions140.65417.36414-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
68 YWHAQinteractor170.46346.03714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
69 YWHAZprotein found in more fusions180.50045.09614-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
70 ZDHHC17protein found in more fusions31.0000zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)
71 ZEB2oncoprotein30.6670.667zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
Rubredoxin (PF00301, IPR024935): Rubredoxin
zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-CCHC_5 (PF14787): GAG-polyprotein viral zinc-finger

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ATP6V1E1interactorvATP-synt_E (PF01991, IPR002842): ATP synthase (E/31 kDa) subunit
2 CCDC85BinteractorCCDC85 (PF10226, IPR019359): CCDC85 family
3 CCL3interactorIL8 (PF00048, IPR001811, SM00199): Small cytokines (intecrine/chemokine), interleukin-8 like
4 COMMD6interactorCOMM_domain (PF07258): COMM domain
5 DCP1AinteractorDCP1 (PF06058, IPR010334): Dcp1-like decapping family
mRNA_decap_C (PF16741, IPR031953): mRNA-decapping enzyme C-terminus
6 DCP1BinteractorDCP1 (PF06058, IPR010334): Dcp1-like decapping family
mRNA_decap_C (PF16741, IPR031953): mRNA-decapping enzyme C-terminus
7 DCP2interactorDCP2 (PF05026, IPR007722, SM01125): Dcp2, box A domain
NUDIX (PF00293, IPR000086): NUDIX domain
8 EDC3interactorFDF (PF09532, IPR019050, SM01199): FDF domain
YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus
LSM14 (PF12701, IPR025609): Scd6-like Sm domain
Edc3_linker (PF16598): Linker region of enhancer of mRNA-decapping protein 3
DUF5096 (PF17019, IPR031512): Domain of unknown function (DUF5096)
9 EXOSC6interactorRNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
10 EXOSC8interactorRNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2
11 HNRNPA2B1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
12 HOXC9interactorHox9_act (PF04617, IPR006711): Hox9 activation region
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
13 LIN28AinteractorCSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
zf-CCHC (PF00098, IPR001878): Zinc knuckle
zf-CCHC_6 (PF15288): Zinc knuckle
14 MED30interactorMed30 (PF11315, IPR021019): Mediator complex subunit 30
15 METTL9interactorDREV (PF05219, IPR007884): DREV methyltransferase
16 NUP214oncoproteindCache_2 (PF08269, IPR004010, SM01049): Cache domain
HisKA (PF00512, IPR003661, SM00388): His Kinase A (phospho-acceptor) domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
Mustang (PF15682, IPR031394): Musculoskeletal, temporally activated-embryonic nuclear protein 1
NUP214 (PF16755): Nucleoporin or Nuclear pore complex subunit NUP214=Nup159
17 PABPC1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
18 PAK4parental proteinPBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
19 PRR5LinteractorHbrB (PF08539, IPR013745): HbrB-like
20 SPRY2suppressorKAR9 (PF08580, IPR013889): Yeast cortical protein KAR9
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
21 TFRConcoproteinPA (PF02225, IPR003137): PA domain
Peptidase_M28 (PF04389, IPR007484): Peptidase family M28
TFR_dimer (PF04253, IPR007365): Transferrin receptor-like dimerisation domain
DUF3855 (PF12967, IPR024482): Domain of Unknown Function with PDB structure (DUF3855)
22 TNFoncoproteinTNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
23 UPF2interactorDDHD (PF02862, IPR004177, SM01127): DDHD domain
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Upf2 (PF04050, IPR007193): Up-frameshift suppressor 2
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
SUFU_C (PF12470, IPR024314): Suppressor of Fused Gli/Ci N terminal binding domain
24 XRN1interactorXRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus
25 ZFP36parental proteinzf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)

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