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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: BF203978 is the fusion of parental proteins ANKRD10, PKMYT1 (from a repository: Thu May 11 09:05:32 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)4
The number (and %) of the onco-proteins1 (25.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)4 (66.67 %)
The number (and %) of affected PPIs3 (75.00 %)
The number of possible different fusions1
PPI diameter2
PPI radius1
The average degree of PPI1.500
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients4 (100.00 %)
The number (and %) of a zero Betweenness Centrality3 (75.00 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: PKMYT1,ANKRD10 All fusions
: BF203978;
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BF203978chimera306.000Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
2 APPBP2interactor100TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
3 NXF1interactor200NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
4 THOC2interactor100Sec62 (PF03839, IPR004728): Translocation protein Sec62
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
Thoc2 (PF11732, IPR021726): Transcription- and export-related complex subunit
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
THOC2_N (PF16134, IPR032302): THO complex subunit 2 N-terminus

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ANKRD10parental proteinAnk_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
2 CCNA2oncoproteinCyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
3 CCNB1oncoproteinAdeno_E1A (PF02703, IPR003853): Early E1A protein
Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
4 CCNB2interactorCyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
5 CDK1oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
6 ELAVL1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
7 MAPK10suppressorPkinase (PF00069, IPR000719): Protein kinase domain
8 MAPK8oncoproteinDUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
9 PIN1suppressorRotamase (PF00639, IPR000297): PPIC-type PPIASE domain
WW (PF00397, IPR001202, SM00456): WW domain
10 PKMYT1parental proteinPkinase (PF00069, IPR000719): Protein kinase domain
11 PLIN3interactorPerilipin (PF03036, IPR004279): Perilipin family
12 PTENsuppressorDSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
13 SPINT2suppressorKunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
14 STEAP3interactorDUF781 (PF05612, IPR008499): Mouse protein of unknown function (DUF781)
F420_oxidored (PF03807, IPR028939): NADP oxidoreductase coenzyme F420-dependent
Ferric_reduct (PF01794, IPR013130): Ferric reductase like transmembrane component
15 TMEM216interactorTransmemb_17 (PF09799, IPR019184): Predicted membrane protein

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