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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BE874494 is the fusion of parental proteins TCF3, NFKBIA (from a repository: Thu Nov 10 14:59:26 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)42
The number (and %) of the onco-proteins25 (59.52 %)
The number (and %) of the tumor suppressors4 (9.52 %)
Total number of binary PPIs (saturation %)180 (20.91 %)
The number (and %) of affected PPIs41 (22.78 %)
The number of possible different fusions13
PPI diameter2
PPI radius1
The average degree of PPI7.429
Assortativity coefficient-0.3847
The network average Clustering coefficient0.600
The number (and %) of a zero Clustering coefficients4 (9.52 %)
The number (and %) of a zero Betweenness Centrality13 (30.95 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: TCF3,NFKBIA All fusions
: BE874494;
Proteins found in more fusions CREBBP (see 5 fusions); POLR2A (see 2 fusions); MALT1 (see 1 fusions); HDAC5 (see 1 fusions); EP300 (see 1 fusions); HDAC4 (see 1 fusions); MTOR (see 1 fusions); CENPF (see 1 fusions); RCOR1 (see 2 fusions); PIK3R1 (see 1 fusions); STAT1 (see 1 fusions); TP53 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BE874494chimera410.1401035.958PRIMA1 (PF16101): Proline-rich membrane anchor 1
2 ABL1oncoprotein100.41715.150Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
3 ARHGAP39interactor100MyTH4 (PF00784, IPR000857, SM00139): MyTH4 domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
WW (PF00397, IPR001202, SM00456): WW domain
4 ASB2interactor31.0000Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
5 BARD1oncoprotein40.6670.286BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
6 BIRC2oncoprotein200BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
7 CAPN1interactor21.0000Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III
Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
8 CASP14interactor100Peptidase_C14 (PF00656, IPR011600): Caspase domain
9 CD7interactor21.0000V-set (PF07686, IPR013106): Immunoglobulin V-set domain
10 CENPFoncoprotein200APG6 (PF04111, IPR007243): Autophagy protein Apg6
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fez1 (PF06818): Fez1
Filament (PF00038, IPR001664): Intermediate filament protein
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7)
IncA (PF04156, IPR007285): IncA protein
Propep_M14 (PF02244, IPR003146): Carboxypeptidase activation peptide
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Usp (PF00582, IPR006016): Universal stress protein family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
CENP-F_N (PF10481, IPR018463): Cenp-F N-terminal domain
CENP-F_C_Rb_bdg (PF10490, IPR018302): Rb-binding domain of kinetochore protein Cenp-F/LEK1
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
DUF4239 (PF14023, IPR025333): Protein of unknown function (DUF4239)
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
11 CREBBPoncoprotein140.51322.717Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
12 EP300oncoprotein160.46730.384Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
13 FBXW8interactor40.6670.583WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
14 HDAC1suppressor130.54514.112FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
15 HDAC2oncoprotein80.6673.036Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
16 HDAC3oncoprotein150.38531.229Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
17 HDAC4oncoprotein80.8101.152Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
18 HDAC5protein found in more fusions110.6227.258Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
19 HNRNPA1interactor80.6196.250RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
20 HNRNPUinteractor70.7142.919CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
21 HOXB7interactor21.0000Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
22 MALT1oncoprotein31.0000Peptidase_C14 (PF00656, IPR011600): Caspase domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
23 MAP3K1oncoprotein50.8330.250zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Pkinase (PF00069, IPR000719): Protein kinase domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
24 MED19interactor31.0000Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
25 MTORoncoprotein60.7001.036DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104)
EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain
V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
TPR_19 (PF14559): Tetratricopeptide repeat
26 NCOR1oncoprotein90.7782.438BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal
Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
Hid1 (PF12722): High-temperature-induced dauer-formation protein
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
RBR (PF17208): RNA binding Region
27 NCOR2oncoprotein100.6895.413CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK)
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family
PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Spt20 (PF12090, IPR021950): Spt20 family
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518)
GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
28 PIK3R1oncoprotein70.5335.186RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
29 PIN1suppressor80.5368.325Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain
WW (PF00397, IPR001202, SM00456): WW domain
30 POLR2Aprotein found in more fusions110.31123.819RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
31 RASA1oncoprotein50.7002.333C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
32 RB1oncoprotein80.6074.472RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
33 RCOR1protein found in more fusions50.6670.622DivIC (PF04977, IPR007060): Septum formation initiator
ELM2 (PF01448, IPR000949): ELM2 domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
FAM76 (PF16046, IPR032017): FAM76 protein
34 SOCS3suppressor50.6003.333SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
35 SPECC1Linteractor21.0000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
DUF4763 (PF15960, IPR031883): Domain of unknown function (DUF4763)
36 SRConcoprotein100.47211.288Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
37 STAT1suppressor110.53310.141SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain
38 TCEA1oncoprotein21.0000Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
39 TP53oncoprotein200.29286.495DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
40 UBE2Iinteractor170.43341.414UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
41 XPO1interactor120.30332.400CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
42 YES1oncoprotein31.0000Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
YdjC (PF04794, IPR006879): YdjC-like protein
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 AIDAinteractorAida_N (PF08910, IPR023421): Aida N-terminus
Aida_C2 (PF14186, IPR025939): Cytoskeletal adhesion
2 ALDH18A1interactorAA_kinase (PF00696, IPR001048): Amino acid kinase family
Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family
3 ANKRD27interactorTCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain
Ribonuc_red_sm (PF00268, IPR000358): Ribonucleotide reductase, small chain
VPS9 (PF02204, IPR003123, SM00167): Vacuolar sorting protein 9 (VPS9) domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
4 ARMT1interactorDUF89 (PF01937, IPR002791): Protein of unknown function DUF89
5 ARRB1interactorArrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
6 ARRB2interactorArrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
7 ATF4oncoproteinbZIP_1 (PF00170, IPR004827): bZIP transcription factor
8 ATOH8interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
9 ATP2A3interactorCation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
10 ATXN3interactorJosephin (PF02099, IPR006155): Josephin
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
11 AURKAoncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
MTBP_C (PF14920, IPR029418): MDM2-binding
12 AVL9interactorAvl9 (PF09794, IPR018307): Transport protein Avl9
Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit
13 BCL10oncoproteinCARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
14 BCORoncoproteinAnk_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
BCOR (PF15808, IPR031628): BCL-6 co-repressor, non-ankyrin-repeat region
PUFD (PF16553, IPR032365): BCORL-PCGF1-binding domain
15 BHLHA15interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
16 BHLHE40interactorHairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
17 BTRConcoproteinWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
18 C14orf166interactorRLL (PF10036, IPR019265): Putative carnitine deficiency-associated protein
19 C1QBPinteractorMAM33 (PF02330, IPR003428): Mitochondrial glycoprotein
DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
20 CALM1interactorEF-hand_7 (PF13499, IPR011992): EF-hand domain pair
21 CANXinteractorCalreticulin (PF00262, IPR001580): Calreticulin family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
22 CBFA2T3oncoproteinNHR2 (PF08788, IPR014896): NHR2 domain like
TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF
zf-MYND (PF01753, IPR002893): MYND finger
Efg1 (PF10153, IPR019310): rRNA-processing protein Efg1
PRIMA1 (PF16101): Proline-rich membrane anchor 1
23 CCT2interactorCpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
24 CDC34oncoproteinUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
25 CHAC2interactorChaC (PF04752, IPR006840): ChaC-like protein
26 CHCHD3interactorDUF737 (PF05300, IPR007964): Protein of unknown function (DUF737)
eIF3g (PF12353, IPR024675): Eukaryotic translation initiation factor 3 subunit G
27 CHUKsuppressorPkinase (PF00069, IPR000719): Protein kinase domain
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
28 CLUoncoproteinClusterin (PF01093, IPR000753): Clusterin
29 COL7A1interactorCollagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
DUF4249 (PF14054, IPR025345): Domain of unknown function (DUF4249)
DUF4992 (PF16383, IPR032155): Domain of unknown function
30 COMMD1interactorCOMMD1_N (PF17221): COMMD1 N-terminal domain
COMM_domain (PF07258): COMM domain
31 COPS2oncoproteinYozE_SAM_like (PF06855, IPR023089): YozE SAM-like fold
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2087 (PF09860, IPR018656): Uncharacterized protein conserved in bacteria (DUF2087)
PCI (PF01399, IPR000717, SM00088): PCI domain
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
32 COPS3interactorRasGEF (PF00617, IPR001895, SM00147): RasGEF domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
33 COX7A2interactorCOX7a (PF02238, IPR003177): Cytochrome c oxidase subunit VII
34 CPDinteractorPeptidase_M14 (PF00246, IPR000834, SM00631): Zinc carboxypeptidase
CarboxypepD_reg (PF13620): Carboxypeptidase regulatory-like domain
35 CSNK1A1oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
36 CSNK2BinteractorCK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
37 CSTAoncoproteinCystatin (PF00031, IPR000010, SM00043): Cystatin domain
38 CTU2interactorCTU2 (PF10288, IPR019407): Cytoplasmic tRNA 2-thiolation protein 2
39 CUEDC1oncoproteinCUE (PF02845, IPR003892, SM00546): CUE domain
40 CUL1oncoproteinCullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
41 DAXXoncoproteinDaxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Nop14 (PF04147, IPR007276): Nop14-like family
RF-1 (PF00472, IPR000352): RF-1 domain
Vpu (PF00558, IPR008187): Vpu protein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
42 DCAF6interactorHerpes_pp85 (PF04637, IPR006731): Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
ATAD4 (PF15321, IPR028237): ATPase family AAA domain containing 4
MRI (PF15325, IPR028278): Modulator of retrovirus infection
WD40_like (PF17005, IPR031544): WD40-like domain
43 DDX17interactorCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Ferritin (PF00210, IPR008331): Ferritin-like domain
GRP (PF07172, IPR010800): Glycine rich protein family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
44 DDX20interactorDEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
45 DENRoncoproteinSUI1 (PF01253, IPR001950): Translation initiation factor SUI1
46 DNAJA3suppressorDnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
47 DNAJC10interactorDnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
48 DNMT1oncoproteinBAH (PF01426, IPR001025, SM00439): BAH domain
DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain
DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
49 DYNLL1interactorDynein_light (PF01221, IPR001372): Dynein light chain type 1
50 EEF1A2oncoproteinGTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
51 EIF5AinteractorEFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain
eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
52 ELAVL1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
53 ELK3interactorEts (PF00178, IPR000418, SM00413): Ets-domain
Translat_reg (PF01818, IPR002702): Bacteriophage translational regulator
54 ERAL1interactorGTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
KH_1 (PF00013, IPR004088, SM00322): KH domain
55 ERC1oncoproteinRBD-FIP (PF09457, IPR019018): FIP domain
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
Cast (PF10174, IPR019323): RIM-binding protein of the cytomatrix active zone
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
56 ERLIN2interactorBand_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
57 FBLinteractorFibrillarin (PF01269, IPR000692): Fibrillarin
58 FBXW11interactorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
59 FLG2interactorS_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
AP3D1 (PF06375): AP-3 complex subunit delta-1
60 FOXH1interactorForkhead (PF00250, IPR001766, SM00339): Forkhead domain
61 G3BP2interactorNTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
62 GNG5interactorG-gamma (PF00631, IPR015898, SM00224): GGL domain
63 GPS1interactorRPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7
PCI (PF01399, IPR000717, SM00088): PCI domain
64 GSE1oncoproteinCENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
Plasmodium_Vir (PF05795, IPR008780): Plasmodium vivax Vir protein
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
DUF3736 (PF12540, IPR022207): Protein of unknown function (DUF3736)
AAA_11 (PF13086): AAA domain
DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
65 HAND1interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
66 HAND2interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
67 HIF1ANinteractorCupin_8 (PF13621): Cupin-like domain
68 HNRNPRinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
69 ID1interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
70 ID2oncoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
71 ID3oncoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
72 ID4oncoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Lipase_3 (PF01764, IPR002921): Lipase (class 3)
73 IKBKAPinteractorIKI3 (PF04762, IPR006849): IKI3 family
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
MMU163 (PF17119, IPR031342): Mitochondrial protein up-regulated during meiosis
74 IKBKBinteractorFliT (PF05400, IPR008622): Flagellar protein FliT
Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
75 IKBKEinteractorIncA (PF04156, IPR007285): IncA protein
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon
76 IKBKGinteractorCENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
77 IKZF4interactorADK_lid (PF05191, IPR007862): Adenylate kinase, active site lid
PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
FancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nuclease
78 IMMTinteractorMitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
79 INO80EinteractorNBP1 (PF08537, IPR013743): Fungal Nap binding protein NBP1
80 ITPK1interactorIns134_P3_kin (PF05770, IPR008656): Inositol 1, 3, 4-trisphosphate 5/6-kinase
81 KAT2AinteractorAcetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
82 KAT2BinteractorAcetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
83 KDM1AinteractorAmino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
84 KIF18AinteractorKinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF4005 (PF13178, IPR025064): Protein of unknown function (DUF4005)
85 LANCL2interactorGlyco_hydro_127 (PF07944, IPR012878): Beta-L-arabinofuranosidase, GH127
LANC_like (PF05147, IPR007822): Lanthionine synthetase C-like protein
86 LBRinteractorERG4_ERG24 (PF01222, IPR001171): Ergosterol biosynthesis ERG4/ERG24 family
LBR_tudor (PF09465, IPR019023): Lamin-B receptor of TUDOR domain
87 LDB1oncoproteinLIM_bind (PF01803): LIM-domain binding protein
88 LGALS7interactorGal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
89 LMX1AinteractorLIM (PF00412, IPR001781, SM00132): LIM domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
90 LYL1oncoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
91 MAP3K14interactorPkinase (PF00069, IPR000719): Protein kinase domain
92 MAP3K7oncoproteinMnd1 (PF03962, IPR005647): Mnd1 family
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
93 MAPK14oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
94 MAPKAPK2oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
95 MAPKAPK3interactorPkinase (PF00069, IPR000719): Protein kinase domain
96 MAVSinteractorIce_nucleation (PF00818, IPR000258): Ice nucleation protein repeat
CARD_2 (PF16739, IPR031964): Caspase recruitment domain
97 MED31interactorMed31 (PF05669, IPR008831): SOH1
98 MEN1oncoproteinMenin (PF05053, IPR007747): Menin
99 MESP2interactorDUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
100 MRPL23interactorRibosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
101 MRPL37interactorPDCD9 (PF07147, IPR010793): Mitochondrial 28S ribosomal protein S30 (PDCD9)
102 MRPL39interactorTGS (PF02824, IPR004095): TGS domain
DUF2469 (PF10611, IPR019592): Protein of unknown function (DUF2469)
103 MRPL44interactordsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain
104 MRPL49interactorImg2 (PF05046, IPR007740): Mitochondrial large subunit ribosomal protein (Img2)
105 MYF5interactorAuxin_repressed (PF05564, IPR008406): Dormancy/auxin associated protein
Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myf5 (PF12232, IPR022032): Myogenic determination factor 5
106 MYF6interactorBasic (PF01586, IPR002546, SM00520): Myogenic Basic domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myf5 (PF12232, IPR022032): Myogenic determination factor 5
107 MYL6BinteractorSapB_1 (PF05184, IPR007856): Saposin-like type B, region 1
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
108 MYO1BinteractorIQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
RNA_pol (PF00940, IPR002092): DNA-dependent RNA polymerase
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
AAA_23 (PF13476): AAA domain
109 MYOD1oncoproteinBasic (PF01586, IPR002546, SM00520): Myogenic Basic domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Mfp-3 (PF04202, IPR007328): Foot protein 3
Myf5 (PF12232, IPR022032): Myogenic determination factor 5
110 MYOGinteractorBasic (PF01586, IPR002546, SM00520): Myogenic Basic domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
111 NDUFB4interactorNDUF_B4 (PF07225, IPR009866): NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
112 NEDD9interactorSerine_rich (PF08824, IPR014928): Serine rich protein interaction domain
DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
113 NEUROD1interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
Neuro_bHLH (PF12533, IPR022575): Neuronal helix-loop-helix transcription factor
114 NFKB1oncoproteinDeath (PF00531, IPR000488, SM00005): Death domain
GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
115 NFKB2oncoproteinAnk (PF00023, IPR002110, SM00248): Ankyrin repeat
Death (PF00531, IPR000488, SM00005): Death domain
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
116 NFKBIAparental proteinAnk (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
117 NFKBIBinteractorAnk_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
118 NFKBIEoncoproteinAnk_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
119 NHLH1interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
120 NHLH2interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
121 NME2P1interactorNA
122 NPLOC4interactorNPL4 (PF05021, IPR007717): NPL4 family
zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region
UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
123 OGDHLinteractorE1_dh (PF00676, IPR001017): Dehydrogenase E1 component
Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
2-oxogl_dehyd_N (PF16078, IPR032106): 2-oxoglutarate dehydrogenase N-terminus
OxoGdeHyase_C (PF16870, IPR031717): 2-oxoglutarate dehydrogenase C-terminal
124 OTUB1interactorPeptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
125 PARP1suppressorBRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain
PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain
WGR (PF05406, IPR008893, SM00773): WGR domain
zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
126 PCBP1oncoproteinBac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
127 PIPinteractorSVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA)
128 PIRinteractorPirin (PF02678, IPR003829): Pirin
Pirin_C (PF05726, IPR008778): Pirin C-terminal cupin domain
129 POLR2CinteractorRNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain
130 POLR2JinteractorRNA_pol_L_2 (PF13656): RNA polymerase Rpb3/Rpb11 dimerisation domain
131 POLRMTinteractorDUF615 (PF04751, IPR006839): Protein of unknown function (DUF615)
PSD2 (PF07624, IPR011478): Protein of unknown function (DUF1585)
RNA_pol (PF00940, IPR002092): DNA-dependent RNA polymerase
PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain
RPOL_N (PF14700, IPR029262): DNA-directed RNA polymerase N-terminal
132 POM121interactorIce_nucleation (PF00818, IPR000258): Ice nucleation protein repeat
Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
POM121 (PF15229): POM121 family
133 PON2interactorArylesterase (PF01731, IPR002640): Arylesterase
134 PPP1R9AinteractorDIRP (PF06584, IPR010561, SM01135): DIRP
FliJ (PF02050, IPR012823): Flagellar FliJ protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
PKI (PF02827, IPR004171): cAMP-dependent protein kinase inhibitor
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
DUF2407_C (PF13373, IPR025390): DUF2407 C-terminal domain
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
135 PRKCAinteractorC2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
136 PRMT5interactorPRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
137 PRPF8oncoproteinPRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain
PROCN (PF08083, IPR012592): PROCN (NUC071) domain
PROCT (PF08084, IPR012984): PROCT (NUC072) domain
RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8
U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8
U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core
138 PRTFDC1interactorPribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain
139 PSMA1interactorProteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
140 PSMA2interactorProteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
141 PSMA4interactorProteasome (PF00227, IPR001353): Proteasome subunit
U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
142 PSMD4interactorUIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
143 PTF1AinteractorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
144 PTPN13oncoproteinFERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
KIND (PF16474, IPR011019, SM00750): Kinase non-catalytic C-lobe domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
PTN13_u3 (PF16599): Unstructured linker region on PTN13 protein between PDZ
145 RBM39oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
146 RELoncoproteinRHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
147 RELAoncoproteinDEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
148 RELBoncoproteinRHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
RelB_leu_zip (PF16180, IPR032399): RelB leucine zipper
RelB_transactiv (PF16181, IPR032400): RelB transactivation domain
149 RHOAoncoproteinRas (PF00071, IPR001806, SM00173): Ras family
150 RNF121interactorzf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Phage_holin_3_6 (PF07332, IPR009937): Putative Actinobacterial Holin-X, holin superfamily III
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
151 RNF14interactorIBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
RWD (PF05773, IPR006575, SM00591): RWD domain
T5orf172 (PF10544, IPR018306, SM00974): T5orf172 domain
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
zf-RING_11 (PF17123, IPR001841): RING-like zinc finger
152 RNF183interactorzf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
153 RPL13interactorRibosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
154 RPL14interactorKOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
155 RPL23AinteractorRibosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain
156 RPL24interactorMAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
157 RPL31interactorRibosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e
158 RPL36AinteractorNOB1_Zn_bind (PF08772, IPR014881): Nin one binding (NOB1) Zn-ribbon like
Ribosomal_L44 (PF00935, IPR000552): Ribosomal protein L44
159 RPL37interactorRibosomal_L37e (PF01907, IPR001569): Ribosomal protein L37e
160 RPN2interactorRibophorin_II (PF05817, IPR008814): Oligosaccharyltransferase subunit Ribophorin II
161 RPS13interactorRibosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain
Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
162 RPS3interactorKH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
163 RPS6KA1oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
164 RPS6KA3interactorPkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
165 RUNX1oncoproteinRunt (PF00853, IPR013524): Runt domain
RunxI (PF08504, IPR013711): Runx inhibition domain
DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
166 RUNX1T1oncoproteinNHR2 (PF08788, IPR014896): NHR2 domain like
TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF
zf-MYND (PF01753, IPR002893): MYND finger
DUF3731 (PF12531, IPR021030): DNA-K related protein
167 RWDD3interactorDUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115)
RWD (PF05773, IPR006575, SM00591): RWD domain
168 SAFBsuppressorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAP (PF02037, IPR003034, SM00513): SAP domain
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
169 SCRN2interactorAAT (PF03417, IPR005079): Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
Peptidase_C69 (PF03577, IPR005322): Peptidase family C69
170 SCXinteractorCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
171 SERPINH1interactorSerpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
172 SETSIPinteractorNAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
173 SF3A3interactorDUF3449 (PF11931, IPR024598): Domain of unknown function (DUF3449)
SF3a60_bindingd (PF12108, IPR021966): Splicing factor SF3a60 binding domain
Telomere_Sde2_2 (PF13297): Telomere stability C-terminal
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
SF3A3 (PF16837, IPR031774): Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9
174 SKP1oncoproteinSkp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain
Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
175 SKP2oncoproteinLRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_2 (PF07723, IPR013101): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
176 SLC25A10interactorMito_carr (PF00153, IPR018108): Mitochondrial carrier protein
177 SLC25A4interactorMito_carr (PF00153, IPR018108): Mitochondrial carrier protein
178 SLC9A3R1oncoproteinEBP50_C (PF09007, IPR015098): EBP50, C-terminal
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
179 SONinteractorAsp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
G-patch (PF01585, IPR000467, SM00443): G-patch domain
tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1
GREB1 (PF15782, IPR028422): Gene regulated by oestrogen in breast cancer
RSRP (PF17069): Arginine/Serine-Rich protein 1
180 SOX2oncoproteinHMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
181 SPDL1interactorPox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
DUF2911 (PF11138, IPR021314): Protein of unknown function (DUF2911)
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
182 SPIN1interactorSpin-Ssty (PF02513, IPR003671): Spin/Ssty Family
183 SSBP1interactorSSB (PF00436, IPR000424): Single-strand binding protein family
184 ST7interactorST7 (PF04184, IPR007311): ST7 protein
185 STK38interactorMEKHLA (PF08670, IPR013978): MEKHLA domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
186 SUMO4interactorSRP9-21 (PF05486): Signal recognition particle 9 kDa protein (SRP9)
Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
187 SUPT3HinteractorTFIID-18kDa (PF02269, IPR003195): Transcription initiation factor IID, 18kD subunit
DUF4093 (PF13331, IPR025156): Domain of unknown function (DUF4093)
188 TADA2AinteractorSWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
189 TAL1oncoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
190 TBC1D24interactorRabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
TLD (PF07534, IPR006571, SM00584): TLD
191 TBCEinteractorCAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
Ubiquitin_2 (PF14560, IPR027933): Ubiquitin-like domain
LRR_9 (PF14580): Leucine-rich repeat
192 TBK1interactorDUF713 (PF05218, IPR007883): Protein of unknown function (DUF713)
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Pkinase (PF00069, IPR000719): Protein kinase domain
193 TCAF1interactorPeptidase_M60 (PF13402, IPR031161): Peptidase M60, enhancin and enhancin-like
194 TCF12oncoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
195 TCF21interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
196 TCF24interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
197 TCF3parental proteinCDC45 (PF02724, IPR003874): CDC45-like protein
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
198 TCF4suppressorCDC45 (PF02724, IPR003874): CDC45-like protein
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
199 TET2interactorTet_JBP (PF12851, IPR024779): Oxygenase domain of the 2OGFeDO superfamily
200 TFF3interactorTrefoil (PF00088, IPR000519, SM00018): Trefoil (P-type) domain
201 TIMM50interactorNIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
202 TLDC1interactorTLD (PF07534, IPR006571, SM00584): TLD
203 TLE1interactorTLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
204 TNFoncoproteinTNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
205 TRE17interactorNA
206 TRIM33oncoproteinPHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Siva (PF05458, IPR022773): Cd27 binding protein (Siva)
Spectrin (PF00435, IPR002017): Spectrin repeat
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
207 TRRAPinteractorBALF1 (PF06861, IPR010677): BALF1 protein
BP28CT (PF08146, IPR012954, SM01036): BP28CT (NUC211) domain
DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
CLASP_N (PF12348, IPR024395): CLASP N terminal
Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal
HEAT_EZ (PF13513): HEAT-like repeat
TRC8_N (PF13705, IPR025754): TRC8 N-terminal domain
ACDC (PF14733, IPR028078): AP2-coincident C-terminal
208 TWIST1oncoproteinACC_epsilon (PF13822, IPR032716): Acyl-CoA carboxylase epsilon subunit
PRR20 (PF15708, IPR031439): Proline-rich protein family 20
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
209 UBE2D1interactorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
210 UBE2D2oncoproteinUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
211 UBE2D3interactorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
212 UBE2L3interactorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
213 UBFD1interactorubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
214 UFD1LinteractorUFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1
215 UQCRC2oncoproteinPeptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
216 USF1oncoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
217 VCPinteractorAAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
218 VDRsuppressorzf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
219 YY1interactorzf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
220 ZBTB7AinteractorBTB (PF00651, IPR013069, SM00225): BTB/POZ domain
GAGA (PF09237, IPR015318): GAGA factor
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
221 ZNF212interactorKRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-LYAR (PF08790, IPR014898): LYAR-type C2HC zinc finger
DUF3669 (PF12417, IPR022137): Zinc finger protein
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger

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