Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BE837753 is the fusion of parental proteins ZNFX1, CCDC181 (from a repository: Thu Feb 1 01:53:49 2018)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)2
The number (and %) of the onco-proteins2 (100.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)2 (200.00 %)
The number (and %) of affected PPIs1 (50.00 %)
The number of possible different fusions2
PPI diameter1
PPI radius1
The average degree of PPI1.000
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients2 (100.00 %)
The number (and %) of a zero Betweenness Centrality2 (100.00 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: CCDC181,ZNFX1 All fusions
: BE837753;
Proteins found in more fusions FYN (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BE837753chimera100AAA_11 (PF13086): AAA domain
2 FYNoncoprotein200Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 AMZ2interactorPeptidase_M10 (PF00413, IPR001818): Matrixin
Peptidase_M54 (PF07998, IPR012962): Peptidase family M54
2 CCDC181parental proteinPatched (PF02460, IPR003392): Patched family
DUF4207 (PF13904): Domain of unknown function (DUF4207)
UPF0767 (PF15990, IPR031933): UPF0767 family
3 CDK4oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
4 CSDE1oncoproteinCSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
SUZ-C (PF12901, IPR024642): SUZ-C motif
S1-like (PF14444, IPR025223): S1-like
5 CXXC4suppressorGlycoprotein_G (PF00802, IPR000925): Pneumovirus attachment glycoprotein G
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
6 DDX27interactorAsp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
7 DRC1interactorGvpK (PF05121, IPR007805): Gas vesicle protein K
Octopine_DH (PF02317, IPR003421): NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
ApoO (PF09769, IPR019166): Apolipoprotein O
NYD-SP28 (PF14772): Sperm tail
NYD-SP28_assoc (PF14775, IPR029440): Sperm tail C-terminal domain
LRR19-TM (PF15176): Leucine-rich repeat family 19 TM domain
8 DROSHAinteractordsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain
Ribonucleas_3_3 (PF14622, IPR000999): Ribonuclease-III-like
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
9 ENO1oncoproteinEnolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
10 HSF2interactorHAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region
Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
HMMR_C (PF15908, IPR031794): Hyaluronan mediated motility receptor C-terminal
11 IMP3interactorRibosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain
S4 (PF01479, IPR002942, SM00363): S4 domain
12 LACTBoncoproteinBeta-lactamase (PF00144, IPR001466): Beta-lactamase
13 MIEF1interactorMab-21 (PF03281, IPR024810): Mab-21 protein
14 MOV10interactorAAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
15 NXF1interactorNTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
16 PCDH1interactorCadherin_2 (PF08266, IPR013164): Cadherin-like
Protocadherin (PF08374, IPR013585): Protocadherin
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
RGCC (PF15151, IPR029252): Response gene to complement 32 protein family
Cadherin_3 (PF16184): Cadherin-like
17 PDK1interactorHATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
BCDHK_Adom3 (PF10436, IPR018955): Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
18 PPP1CAsuppressorMetallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
19 SCAF11interactorDUF566 (PF04484, IPR007573): Family of unknown function (DUF566)
Phage_XkdX (PF09693, IPR010022): Phage uncharacterised protein (Phage_XkdX)
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
20 SHMT2interactorSHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
21 SS18L2interactorSSXT (PF05030, IPR007726): SSXT protein (N-terminal region)
22 TUBA1CinteractorTubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
23 UGGT1interactorGlyco_transf_8 (PF01501, IPR002495): Glycosyl transferase family 8
UDP-g_GGTase (PF06427, IPR009448): UDP-glucose:Glycoprotein Glucosyltransferase
24 XPO1interactorCRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
25 ZNFX1parental proteinzf-NF-X1 (PF01422, IPR000967, SM00438): NF-X1 type zinc finger
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil

B a c k    t o    T o p ⇑