1 |
BE830802 | chimera | 138 | 0.062 | 13151.032 | DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FAT (PF02259, IPR003151): FAT domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats TPR_19 (PF14559): Tetratricopeptide repeat |
2 |
ABL1 | oncoprotein | 15 | 0.396 | 27.882 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2 |
3 |
AKT1 | oncoprotein | 28 | 0.276 | 135.639 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
4 |
AKT1S1 | interactor | 9 | 0.679 | 2.392 | Pap_E4 (PF02711, IPR003861): E4 protein PRAS (PF15798, IPR026682): Proline-rich AKT1 substrate 1 |
5 |
AMBRA1 | interactor | 6 | 0.733 | 1.750 | Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Spt20 (PF12090, IPR021950): Spt20 family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
6 |
ASPM | oncoprotein | 3 | 0.667 | 0.333 | CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD) CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RST (PF12174, IPR022003): RCD1-SRO-TAF4 (RST) plant domain ASH (PF15780, IPR031549): Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin |
7 |
BAG6 | interactor | 8 | 0.286 | 12.633 | DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939) DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538) PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
8 |
BCL2L1 | oncoprotein | 9 | 0.464 | 6.256 | Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4 |
9 |
BRAT1 | oncoprotein | 6 | 0.400 | 5.915 | HEAT (PF02985, IPR000357): HEAT repeat HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
10 |
BRCA1 | suppressor | 22 | 0.238 | 104.690 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
11 |
BSG | interactor | 4 | 0.667 | 1.667 | Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
12 |
C7orf25 | interactor | 1 | 0 | 0 | DUF1308 (PF07000, IPR010733): Protein of unknown function (DUF1308) DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349) |
13 |
CA14 | interactor | 1 | 0 | 0 | Carb_anhydrase (PF00194, IPR001148, SM01057): Eukaryotic-type carbonic anhydrase NicO (PF03824, IPR011541): High-affinity nickel-transport protein |
14 |
CD244 | interactor | 1 | 0 | 0 | Receptor_2B4 (PF11465, IPR024303): Natural killer cell receptor 2B4 WBP-1 (PF11669, IPR021684): WW domain-binding protein 1 Ig_2 (PF13895, IPR007110): Immunoglobulin domain |
15 |
CD274 | oncoprotein | 2 | 1.000 | 0 | C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E V-set (PF07686, IPR013106): Immunoglobulin V-set domain |
16 |
CDC37 | protein found in more fusions | 18 | 0.294 | 42.271 | CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding Rho_Binding (PF08912, IPR015008): Rho Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding |
17 |
CFP | oncoprotein | 1 | 0 | 0 | TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain |
18 |
CHUK | suppressor | 18 | 0.434 | 28.940 | Pkinase (PF00069, IPR000719): Protein kinase domain IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
19 |
CLIP1 | oncoprotein | 1 | 0 | 0 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain CP12 (PF02672, IPR003823, SM01093): CP12 domain DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848) FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) FliJ (PF02050, IPR012823): Flagellar FliJ protein Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain SlyX (PF04102, IPR007236): SlyX ApoO (PF09769, IPR019166): Apolipoprotein O Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) Leu_zip (PF15294): Leucine zipper CLIP1_ZNF (PF16641, IPR032108): CLIP1 zinc knuckle PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase |
20 |
DCP2 | interactor | 2 | 1.000 | 0 | DCP2 (PF05026, IPR007722, SM01125): Dcp2, box A domain NUDIX (PF00293, IPR000086): NUDIX domain |
21 |
DDB1 | protein found in more fusions | 15 | 0.341 | 28.775 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
22 |
DEPTOR | interactor | 8 | 0.750 | 2.686 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ_2 (PF13180, IPR001478): PDZ domain Complex1_LYR_2 (PF13233): Complex1_LYR-like Caskin1-CID (PF16600): Caskin1 CASK-interaction domain |
23 |
DIAPH1 | interactor | 1 | 0 | 0 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Drf_DAD (PF06345, IPR010465): DRF Autoregulatory Domain Drf_FH1 (PF06346, IPR009408): Formin Homology Region 1 Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain Glucan_synthase (PF02364, IPR003440): 1,3-beta-glucan synthase component Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region |
24 |
EGFR | oncoprotein | 33 | 0.175 | 269.216 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
25 |
EIF3B | interactor | 10 | 0.444 | 14.821 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal PALB2_WD40 (PF16756, IPR031920): Partner and localizer of BRCA2 WD40 domain Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF |
26 |
EIF3C | oncoprotein | 6 | 0.800 | 1.233 | eIF-3c_N (PF05470, IPR008905): Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI (PF01399, IPR000717, SM00088): PCI domain |
27 |
EIF3F | suppressor | 6 | 0.667 | 2.600 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function |
28 |
EIF4E | oncoprotein | 8 | 0.500 | 10.033 | IF4E (PF01652, IPR001040): Eukaryotic initiation factor 4E |
29 |
EIF4EBP1 | oncoprotein | 10 | 0.311 | 22.058 | eIF_4EBP (PF05456, IPR008606): Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) |
30 |
EIF4EBP2 | interactor | 3 | 1.000 | 0 | eIF_4EBP (PF05456, IPR008606): Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) |
31 |
FBXW7 | suppressor | 9 | 0.357 | 10.412 | Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like |
32 |
FKBP1A | interactor | 4 | 0.667 | 0.667 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase Hemopexin (PF00045, IPR018487, SM00120): Hemopexin |
33 |
FKBP8 | protein found in more fusions | 9 | 0.393 | 9.141 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat |
34 |
GADD45A | suppressor | 6 | 0.600 | 2.389 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
35 |
GNB1 | interactor | 8 | 0.500 | 9.067 | Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
36 |
GNB2 | interactor | 10 | 0.467 | 14.287 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat CALM_bind (PF16025): Calcium-dependent calmodulin binding WD40_like (PF17005, IPR031544): WD40-like domain |
37 |
GNB3 | interactor | 2 | 1.000 | 0 | Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
38 |
GNB5 | interactor | 2 | 1.000 | 0 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain |
39 |
GNG2 | interactor | 7 | 0.429 | 10.567 | G-gamma (PF00631, IPR015898, SM00224): GGL domain SidE (PF12252, IPR021014): Dot/Icm substrate protein |
40 |
GPHN | oncoprotein | 3 | 1.000 | 0 | MoCF_biosynth (PF00994, IPR001453, SM00852): Probable molybdopterin binding domain MoeA_C (PF03454, IPR005111): MoeA C-terminal region (domain IV) MoeA_N (PF03453, IPR005110): MoeA N-terminal region (domain I and II) Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat |
41 |
GSK3B | suppressor | 15 | 0.308 | 36.327 | Pkinase (PF00069, IPR000719): Protein kinase domain |
42 |
GTF3C1 | interactor | 5 | 0.500 | 2.737 | B-block_TFIIIC (PF04182, IPR007309): B-block binding subunit of TFIIIC |
43 |
HNRNPD | oncoprotein | 10 | 0.361 | 14.093 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
44 |
HSPA4 | interactor | 31 | 0.241 | 204.434 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
45 |
HTR6 | interactor | 4 | 0.667 | 1.167 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
46 |
IKBKB | protein found in more fusions | 16 | 0.486 | 19.510 | FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
47 |
IKBKG | interactor | 18 | 0.463 | 29.486 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
48 |
ILK | suppressor | 11 | 0.400 | 14.067 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
49 |
IRS1 | interactor | 11 | 0.545 | 8.605 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain |
50 |
LAMTOR2 | interactor | 5 | 1.000 | 0 | Robl_LC7 (PF03259, IPR004942, SM00960): Roadblock/LC7 domain |
51 |
LARS | interactor | 4 | 0.667 | 1.286 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V) |
52 |
LLGL2 | interactor | 4 | 0.667 | 1.000 | Lgl_C (PF08596, IPR013905): Lethal giant larvae(Lgl) like, C-terminal LLGL (PF08366, IPR013577): LLGL2 WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N (PF14655, IPR032839): Rab3 GTPase-activating protein regulatory subunit N-terminus |
53 |
LRPAP1 | interactor | 2 | 1.000 | 0 | Alpha-2-MRAP_C (PF06401, IPR010483): Alpha-2-macroglobulin RAP, C-terminal domain Alpha-2-MRAP_N (PF06400, IPR009066): Alpha-2-macroglobulin RAP, N-terminal domain |
54 |
LYPD3 | oncoprotein | 2 | 1.000 | 0 | DUF753 (PF05444, IPR008472): Protein of unknown function (DUF753) UPAR_LY6 (PF00021, IPR001526): u-PAR/Ly-6 domain |
55 |
MAF1 | interactor | 2 | 0 | 0 | Maf1 (PF09174, IPR015257): Maf1 regulator |
56 |
MAP3K3 | oncoprotein | 10 | 0.528 | 4.700 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain |
57 |
MAPK8 | oncoprotein | 14 | 0.462 | 17.870 | DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530) Pkinase (PF00069, IPR000719): Protein kinase domain |
58 |
MAPKAP1 | interactor | 14 | 0.374 | 31.030 | SIN1 (PF05422, IPR008828): Stress-activated map kinase interacting protein 1 (SIN1) CRIM (PF16978, IPR031567): SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH (PF16979, IPR031313): SAPK-interacting protein 1 (Sin1), Pleckstrin-homology |
59 |
METAP2 | oncoprotein | 3 | 0.667 | 0.667 | Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 SRP72 (PF08492, IPR013699): SRP72 RNA-binding domain TSGP1 (PF07771, IPR011694): Tick salivary peptide group 1 |
60 |
MLST8 | interactor | 15 | 0.352 | 42.181 | Hira (PF07569, IPR011494): TUP1-like enhancer of split WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 |
61 |
MLXIP | interactor | 2 | 1.000 | 0 | ZapB (PF06005, IPR009252): Cell division protein ZapB HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Stm1_N (PF09598, IPR019084): Stm1 Nucleoporin_FG2 (PF15967): Nucleoporin FG repeated region |
62 |
MLXIPL | interactor | 2 | 1.000 | 0 | ZapB (PF06005, IPR009252): Cell division protein ZapB HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
63 |
MOV10 | interactor | 16 | 0.250 | 44.087 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
64 |
MTA2 | interactor | 6 | 0.533 | 5.133 | BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Resolvase (PF00239, IPR006119, SM00857): Resolvase, N terminal domain DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger |
65 |
MTMR3 | oncoprotein | 3 | 1.000 | 0 | FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger |
66 |
NAF1 | interactor | 3 | 0.667 | 0.667 | AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein Gar1 (PF04410, IPR007504): Gar1/Naf1 RNA binding region SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
67 |
NBN | suppressor | 7 | 0.667 | 2.850 | FHA (PF00498, IPR000253, SM00240): FHA domain Nbs1_C (PF08599, IPR013908): DNA damage repair protein Nbs1 NIBRIN_BRCT_II (PF16508, IPR032429): Second BRCT domain on Nijmegen syndrome breakage protein RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
68 |
NCBP1 | interactor | 9 | 0.333 | 17.400 | MIF4G (PF02854, IPR003890, SM00543): MIF4G domain MIF4G_like (PF09088, IPR015172): MIF4G like MIF4G_like_2 (PF09090, IPR015174): MIF4G like SlyX (PF04102, IPR007236): SlyX |
69 |
NFKBIA | oncoprotein | 10 | 0.489 | 8.955 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
70 |
NT5E | interactor | 2 | 1.000 | 0 | 5_nucleotid_C (PF02872, IPR008334): 5'-nucleotidase, C-terminal domain Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase |
71 |
NXF1 | interactor | 22 | 0.243 | 88.274 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
72 |
PA2G4 | interactor | 9 | 0.444 | 9.140 | Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein TraC (PF07820, IPR012930): TraC-like protein |
73 |
PARK2 | suppressor | 20 | 0.251 | 82.072 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
74 |
PDIA3 | interactor | 8 | 0.429 | 9.675 | Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
75 |
PDK1 | interactor | 6 | 0.600 | 1.119 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 (PF10436, IPR018955): Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase |
76 |
PLD2 | interactor | 7 | 0.524 | 2.952 | PH (PF00169, IPR001849, SM00233): PH domain PLDc (PF00614, IPR001736, SM00155): Phospholipase D Active site motif PX (PF00787, IPR001683, SM00312): PX domain PLDc_2 (PF13091, IPR025202): PLD-like domain |
77 |
PML | suppressor | 13 | 0.333 | 26.247 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
78 |
PPP2R2A | interactor | 5 | 0.600 | 1.500 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
79 |
PREX1 | oncoprotein | 4 | 1.000 | 0 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain |
80 |
PREX2 | interactor | 1 | 0 | 0 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain |
81 |
PRKAA1 | suppressor | 10 | 0.422 | 12.998 | Pkinase (PF00069, IPR000719): Protein kinase domain AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase |
82 |
PRKAR1A | suppressor | 6 | 0.700 | 1.100 | RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain |
83 |
PRKCA | interactor | 14 | 0.308 | 23.617 | C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
84 |
PRKCD | suppressor | 13 | 0.394 | 16.279 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
85 |
PRR5 | suppressor | 5 | 0.800 | 0.900 | HbrB (PF08539, IPR013745): HbrB-like |
86 |
PRR5L | interactor | 3 | 1.000 | 0 | HbrB (PF08539, IPR013745): HbrB-like |
87 |
RAB1A | oncoprotein | 5 | 0.600 | 3.000 | Ras (PF00071, IPR001806, SM00173): Ras family |
88 |
RAP1A | suppressor | 6 | 0.400 | 5.467 | Ras (PF00071, IPR001806, SM00173): Ras family |
89 |
RAP2A | oncoprotein | 5 | 0.400 | 1.929 | Ras (PF00071, IPR001806, SM00173): Ras family |
90 |
RHEB | oncoprotein | 6 | 0.467 | 5.417 | Ras (PF00071, IPR001806, SM00173): Ras family |
91 |
RHEBL1 | interactor | 2 | 1.000 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
92 |
RICTOR | interactor | 33 | 0.203 | 277.464 | RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_N (PF14664, IPR028267): Rapamycin-insensitive companion of mTOR, N-term RICTOR_phospho (PF14665, IPR029259): Rapamycin-insensitive companion of mTOR, phosphorylation-site RICTOR_M (PF14666, IPR029451): Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V (PF14668, IPR029452): Rapamycin-insensitive companion of mTOR, domain 5 |
93 |
RP2 | interactor | 2 | 1.000 | 0 | NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase TBCC (PF07986, IPR012945): Tubulin binding cofactor C |
94 |
RPL23 | interactor | 11 | 0.527 | 11.827 | Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e |
95 |
RPL23A | interactor | 11 | 0.509 | 14.697 | Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23 Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain |
96 |
RPL26 | oncoprotein | 7 | 0.810 | 1.036 | TP2 (PF01254, IPR000678): Nuclear transition protein 2 Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal |
97 |
RPL5 | suppressor | 10 | 0.694 | 4.978 | Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18 |
98 |
RPS6 | interactor | 15 | 0.486 | 25.942 | Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574) |
99 |
RPS6KB1 | interactor | 23 | 0.273 | 102.894 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
100 |
RPTOR | protein found in more fusions | 54 | 0.128 | 949.598 | HEAT (PF02985, IPR000357): HEAT repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 (PF13646): HEAT repeats Raptor_N (PF14538, IPR029347): Raptor N-terminal CASPase like domain |
101 |
RRAGB | interactor | 6 | 0.867 | 1.000 | Gtr1_RagA (PF04670, IPR006762): Gtr1/RagA G protein conserved region |
102 |
RRAGC | interactor | 7 | 0.762 | 2.833 | Gtr1_RagA (PF04670, IPR006762): Gtr1/RagA G protein conserved region |
103 |
RRAGD | interactor | 6 | 0.800 | 2.000 | Gtr1_RagA (PF04670, IPR006762): Gtr1/RagA G protein conserved region |
104 |
RUVBL1 | oncoprotein | 14 | 0.423 | 23.781 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
105 |
RUVBL2 | oncoprotein | 15 | 0.385 | 30.654 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
106 |
SCN2B | interactor | 2 | 1.000 | 0 | DUF1191 (PF06697, IPR010605): Protein of unknown function (DUF1191) V-set (PF07686, IPR013106): Immunoglobulin V-set domain |
107 |
SEPT2 | oncoprotein | 3 | 0.667 | 0.500 | FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger Septin (PF00735, IPR000038): Septin |
108 |
SGK1 | oncoprotein | 14 | 0.397 | 24.022 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain PX (PF00787, IPR001683, SM00312): PX domain |
109 |
SGTB | interactor | 2 | 1.000 | 0 | TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat XPC-binding (PF09280, IPR015360): XPC-binding domain TPR_11 (PF13414, IPR011990): TPR repeat SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA |
110 |
SHMT2 | interactor | 8 | 0.286 | 10.183 | SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase |
111 |
SIRT1 | suppressor | 14 | 0.410 | 25.614 | DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
112 |
SIRT7 | interactor | 17 | 0.316 | 55.937 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
113 |
SQSTM1 | oncoprotein | 24 | 0.281 | 113.170 | PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain |
114 |
STAT1 | suppressor | 15 | 0.330 | 30.635 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain |
115 |
STAT3 | suppressor | 16 | 0.248 | 48.471 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
116 |
STK38 | interactor | 5 | 0.667 | 0.571 | MEKHLA (PF08670, IPR013978): MEKHLA domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
117 |
SUMO1 | interactor | 7 | 0.667 | 1.833 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like |
118 |
SUZ12 | suppressor | 11 | 0.333 | 17.086 | DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070) VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein |
119 |
SYNCRIP | interactor | 5 | 0.700 | 1.333 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
120 |
TELO2 | interactor | 10 | 0.511 | 12.906 | Telomere_reg-2 (PF10193, IPR019337): Telomere length regulation protein HEAT_2 (PF13646): HEAT repeats |
121 |
TERF1 | interactor | 13 | 0.333 | 22.960 | TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
122 |
TERT | oncoprotein | 12 | 0.364 | 19.321 | RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain |
123 |
TNFAIP3 | suppressor | 11 | 0.533 | 8.367 | OTU (PF02338, IPR003323): OTU-like cysteine protease zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger Thioredoxin_3 (PF13192, IPR012336): Thioredoxin domain |
124 |
TP53 | suppressor | 33 | 0.214 | 249.306 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
125 |
TRAF2 | interactor | 13 | 0.394 | 24.388 | MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
126 |
TRAF6 | protein found in more fusions | 18 | 0.382 | 44.115 | SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
127 |
TRMT61A | interactor | 1 | 0 | 0 | GCD14 (PF08704, IPR014816): tRNA methyltransferase complex GCD14 subunit GCD14_N (PF14801): tRNA methyltransferase complex GCD14 subunit N-term |
128 |
TTI1 | interactor | 10 | 0.378 | 24.369 | Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat VHS (PF00790, IPR002014, SM00288): VHS domain CLASP_N (PF12348, IPR024395): CLASP N terminal |
129 |
UBQLN1 | protein found in more fusions | 5 | 0.500 | 1.733 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B FAM199X (PF15814, IPR029672): Protein family FAM199X |
130 |
ULK1 | protein found in more fusions | 10 | 0.528 | 9.743 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF3543 (PF12063, IPR022708): Domain of unknown function (DUF3543) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
131 |
USP9X | interactor | 9 | 0.417 | 9.916 | DUF1722 (PF08349, IPR013560): Protein of unknown function (DUF1722) UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain |
132 |
VCP | protein found in more fusions | 28 | 0.208 | 188.834 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
133 |
VPS16 | interactor | 2 | 1.000 | 0 | Vps16_C (PF04840, IPR006925): Vps16, C-terminal region Vps16_N (PF04841, IPR006926): Vps16, N-terminal region |
134 |
VSIG2 | interactor | 2 | 1.000 | 0 | V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
135 |
XPO1 | interactor | 41 | 0.155 | 520.379 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
136 |
YEATS4 | interactor | 4 | 1.000 | 0 | YEATS (PF03366, IPR005033): YEATS family SOGA (PF11365, IPR027881): Protein SOGA |
137 |
YWHAQ | interactor | 12 | 0.424 | 14.667 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
138 |
YWHAZ | protein found in more fusions | 23 | 0.286 | 81.643 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
139 |
ZSCAN26 | interactor | 2 | 1.000 | 0 | C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain SCAN (PF02023, IPR003309, SM00431): SCAN domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |