Find Fusion Network

Fusion ID:
Protein names:

Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BE762364 is the fusion of parental proteins PLP2 (from a repository: Tue Jan 31 01:46:50 2017)

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Force Directed
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)19
The number (and %) of the onco-proteins3 (15.79 %)
The number (and %) of the tumor suppressors1 (5.26 %)
Total number of binary PPIs (saturation %)28 (16.37 %)
The number (and %) of affected PPIs18 (64.29 %)
The number of possible different fusions1
PPI diameter2
PPI radius1
The average degree of PPI2.421
Assortativity coefficient-0.3527
The network average Clustering coefficient0.265
The number (and %) of a zero Clustering coefficients12 (63.16 %)
The number (and %) of a zero Betweenness Centrality16 (84.21 %)


List of the fusions

PPI for parental proteins: PLP2 All fusions
: BE762364;
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 BE762364chimera180.033290.000MARVEL (PF01284, IPR008253): Membrane-associating domain
2 CCDC155interactor100CorA (PF01544, IPR002523): CorA-like Mg2+ transporter protein
EF-hand_9 (PF14658): EF-hand domain
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
3 CD2BP2interactor100GYF (PF02213, IPR003169, SM00444): GYF domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region
4 CEP290interactor100ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DivIC (PF04977, IPR007060): Septum formation initiator
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
Fez1 (PF06818): Fez1
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
HemY_N (PF07219, IPR010817): HemY protein N-terminus
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
Mnd1 (PF03962, IPR005647): Mnd1 family
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Rho_Binding (PF08912, IPR015008): Rho Binding
Sec20 (PF03908, IPR005606): Sec20
Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Swi5 (PF07061, IPR010760): Swi5
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
LIDHydrolase (PF10230, IPR019363): Lipid-droplet associated hydrolase
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
FAM76 (PF16046, IPR032017): FAM76 protein
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
CEP209_CC5 (PF16574, IPR032321): Coiled-coil region of centrosome protein CE290
5 DHODHinteractor21.0000DHO_dh (PF01180, IPR012135): Dihydroorotate dehydrogenase
FMN_dh (PF01070, IPR000262): FMN-dependent dehydrogenase
PASTA (PF03793, IPR005543, SM00740): PASTA domain
6 HNRNPFinteractor100RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
7 IKBKAPinteractor200IKI3 (PF04762, IPR006849): IKI3 family
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
MMU163 (PF17119, IPR031342): Mitochondrial protein up-regulated during meiosis
8 ILF3oncoprotein40.5003.000dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
9 NUDCD2interactor100CS (PF04969, IPR007052): CS domain
DUF3110 (PF11360, IPR021503): Protein of unknown function (DUF3110)
10 PTCD3interactor21.0000PPR (PF01535, IPR002885): PPR repeat
PPR_2 (PF13041, IPR002885): PPR repeat family
PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain
11 S100A11suppressor200S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
12 SFXN3interactor100Mtc (PF03820, IPR004686): Tricarboxylate carrier
13 SGO2interactor100DivIC (PF04977, IPR007060): Septum formation initiator
Shugoshin_C (PF07557, IPR011515): Shugoshin C terminus
VitD-bind_III (PF09164, IPR015247): Vitamin D binding protein, domain III
Tox-SHH (PF15652, IPR028900): HNH/Endo VII superfamily toxin with a SHH signature
14 SHBGoncoprotein200Laminin_G_1 (PF00054, IPR001791): Laminin G domain
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
15 SLC12A4interactor21.0000AA_permease (PF00324, IPR004841): Amino acid permease
SLC12 (PF03522, IPR018491): Solute carrier family 12
16 STT3Binteractor21.0000STT3 (PF02516, IPR003674): Oligosaccharyl transferase STT3 subunit
17 SYNCRIPinteractor40.5003.000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
18 TMEM79interactor200MAPEG (PF01124, IPR001129): MAPEG family
19 VKORC1interactor200VKOR (PF07884, IPR012932, SM00756): Vitamin K epoxide reductase family

B a c k    t o    T o p ⇑

List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 CLN8interactorTRAM_LAG1_CLN8 (PF03798, IPR006634): TLC domain
2 LACC1interactorCu-oxidase_4 (PF02578, IPR003730): Multi-copper polyphenol oxidoreductase laccase
3 LAGE3interactorPcc1 (PF09341, IPR015419): Transcription factor Pcc1
4 MRPL30interactorRibosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
5 MRPL41interactorMRP-L27 (PF09809, IPR019189): Mitochondrial ribosomal protein L27
6 MRPL57interactorMRP-63 (PF14978, IPR016576): Mitochondrial ribosome protein 63
7 MRPL9interactorRibosomal_L9_N (PF01281, IPR020070): Ribosomal protein L9, N-terminal domain
8 PLP2parental proteinMARVEL (PF01284, IPR008253): Membrane-associating domain

B a c k    t o    T o p ⇑