1 |
BE731511 | chimera | 160 | 0.048 | 19617.695 | MOZ_SAS (PF01853, IPR002717): MOZ/SAS family |
2 |
ANGPTL4 | suppressor | 4 | 0.833 | 0.222 | SlyX (PF04102, IPR007236): SlyX Fibrinogen_C (PF00147, IPR002181, SM00186): Fibrinogen beta and gamma chains, C-terminal globular domain |
3 |
APBB1 | interactor | 8 | 0.429 | 11.000 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) WW (PF00397, IPR001202, SM00456): WW domain RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID) |
4 |
APLP1 | interactor | 5 | 0.700 | 3.000 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus Ints3 (PF10189, IPR019333): Integrator complex subunit 3 APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
5 |
APLP2 | interactor | 2 | 1.000 | 0 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding ELM2 (PF01448, IPR000949): ELM2 domain Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain Usp (PF00582, IPR006016): Universal stress protein family YL1 (PF05764, IPR008895): YL1 nuclear protein APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
6 |
APP | protein found in more fusions | 31 | 0.138 | 329.997 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
7 |
AR | oncoprotein | 23 | 0.333 | 88.658 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
8 |
ARIH2 | protein found in more fusions | 8 | 0.619 | 6.119 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zinc_ribbon_12 (PF11331, IPR021480): Probable zinc-ribbon domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING PRAS (PF15798, IPR026682): Proline-rich AKT1 substrate 1 |
9 |
ATF2 | oncoprotein | 21 | 0.295 | 77.337 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type |
10 |
ATF3 | suppressor | 12 | 0.455 | 10.218 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
11 |
ATM | suppressor | 18 | 0.353 | 37.759 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 |
12 |
BARD1 | suppressor | 17 | 0.283 | 62.621 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
13 |
BCL3 | oncoprotein | 8 | 0.536 | 8.527 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) |
14 |
BMI1 | oncoprotein | 20 | 0.304 | 78.596 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
15 |
C14orf169 | interactor | 3 | 1.000 | 0 | Cupin_4 (PF08007, IPR003347): Cupin superfamily protein |
16 |
C1orf174 | interactor | 2 | 1.000 | 0 | UPF0688 (PF15772, IPR031530): UPF0688 family |
17 |
CBX8 | interactor | 16 | 0.210 | 72.982 | Atrophin-1 (PF03154, IPR002951): Atrophin-1 family Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain RBR (PF17208): RNA binding Region CBX7_C (PF17218): CBX family C-terminal motif |
18 |
CCDC106 | interactor | 4 | 0.500 | 0.950 | CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 |
19 |
CCDC136 | suppressor | 3 | 0.667 | 0.333 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus Com_YlbF (PF06133, IPR010368): Control of competence regulator ComK, YlbF/YmcA ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Sec34 (PF04136, IPR007265): Sec34-like family Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding FlxA (PF14282, IPR025577): FlxA-like protein PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
20 |
CCDC8 | interactor | 12 | 0.327 | 24.989 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
21 |
CDK5RAP2 | interactor | 4 | 0.500 | 2.667 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 bZIP_1 (PF00170, IPR004827): bZIP transcription factor CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 DUF1993 (PF09351, IPR018531): Domain of unknown function (DUF1993) IncA (PF04156, IPR007285): IncA protein LPP (PF04728, IPR006817): Lipoprotein leucine-zipper Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein TSC22 (PF01166, IPR000580): TSC-22/dip/bun family Tup_N (PF08581, IPR013890): Tup N-terminal CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain |
22 |
CDKN2A | suppressor | 14 | 0.418 | 28.261 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
23 |
CEBPA | suppressor | 9 | 0.357 | 5.524 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper |
24 |
CREB1 | oncoprotein | 11 | 0.533 | 11.303 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function |
25 |
CREBBP | suppressor | 29 | 0.302 | 123.894 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
26 |
CRELD1 | interactor | 2 | 1.000 | 0 | DUF326 (PF03860, IPR005560): Domain of Unknown Function (DUF326) EGF_2 (PF07974, IPR013111): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain DUF3456 (PF11938, IPR021852): TLR4 regulator and MIR-interacting MSAP cEGF (PF12662, IPR026823): Complement Clr-like EGF-like |
27 |
CSTF2 | interactor | 6 | 0.333 | 7.786 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2 |
28 |
CUL3 | protein found in more fusions | 21 | 0.232 | 101.612 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
29 |
DLEU1 | suppressor | 2 | 1.000 | 0 | DD_K (PF12121, IPR022731): Dermaseptin |
30 |
DMAP1 | interactor | 13 | 0.397 | 32.191 | DMAP1 (PF05499, IPR008468): DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like (PF16282, IPR032563): SANT/Myb-like domain of DAMP1 |
31 |
DNMT1 | suppressor | 11 | 0.444 | 12.674 | BAH (PF01426, IPR001025, SM00439): BAH domain DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain |
32 |
DNTTIP2 | interactor | 5 | 0.500 | 1.983 | BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II) E7 (PF00527, IPR000148): E7 protein, Early protein Fcf2 (PF08698, IPR014810): Fcf2 pre-rRNA processing FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) |
33 |
DUSP23 | interactor | 1 | 0 | 0 | DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family PTPlike_phytase (PF14566): Inositol hexakisphosphate |
34 |
E2F1 | suppressor | 13 | 0.449 | 15.265 | Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
35 |
EFNA1 | interactor | 1 | 0 | 0 | Ephrin (PF00812, IPR001799): Ephrin |
36 |
EP300 | oncoprotein | 47 | 0.191 | 533.183 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
37 |
EP400 | oncoprotein | 12 | 0.515 | 17.926 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide DDHD (PF02862, IPR004177, SM01127): DDHD domain GN3L_Grn1 (PF08701, IPR014813): GNL3L/Grn1 putative GTPase HSA (PF07529, IPR014012, SM00573): HSA Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF3304 (PF11745, IPR021733): Protein of unknown function (DUF3304) DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381) Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch DUF3573 (PF12097, IPR021956): Protein of unknown function (DUF3573) Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain EP400_N (PF15790, IPR031575): E1A-binding protein p400, N-terminal |
38 |
ESR1 | suppressor | 33 | 0.248 | 240.962 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
39 |
ESR2 | suppressor | 10 | 0.667 | 5.147 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ERbeta_N (PF12497, IPR021064): Estrogen receptor beta |
40 |
FAM135B | interactor | 1 | 0 | 0 | DUF676 (PF05057, IPR007751): Putative serine esterase (DUF676) DUF3657 (PF12394, IPR022122): Protein of unknown function (DUF3657) |
41 |
FAM173A | interactor | 3 | 0.667 | 0.500 | Methyltransf_23 (PF13489): Methyltransferase domain |
42 |
FANCD2 | oncoprotein | 6 | 0.533 | 2.158 | FancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nuclease |
43 |
FOXO6 | suppressor | 3 | 1.000 | 0 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family |
44 |
GADD45G | suppressor | 7 | 0.476 | 6.158 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
45 |
GAPDH | oncoprotein | 16 | 0.524 | 19.425 | Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein |
46 |
GEMIN7 | interactor | 1 | 0 | 0 | Gemin7 (PF11095, IPR020338): Gem-associated protein 7 (Gemin7) SUZ-C (PF12901, IPR024642): SUZ-C motif |
47 |
GET4 | interactor | 2 | 1.000 | 0 | DUF410 (PF04190, IPR007317): Protein of unknown function (DUF410) Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1 |
48 |
GMCL1 | interactor | 5 | 0.500 | 2.333 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain |
49 |
GOLGA2 | interactor | 8 | 0.464 | 11.122 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5 |
50 |
GSTO1 | interactor | 3 | 0.667 | 0.400 | GST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain |
51 |
H2AFX | suppressor | 19 | 0.333 | 63.353 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
52 |
H2AFZ | interactor | 9 | 0.611 | 9.500 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
53 |
HABP4 | interactor | 2 | 1.000 | 0 | HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
54 |
HAP1 | interactor | 12 | 0.273 | 36.333 | HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) |
55 |
HDAC6 | oncoprotein | 14 | 0.295 | 27.312 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP) zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein |
56 |
HDAC7 | protein found in more fusions | 8 | 0.286 | 8.510 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO |
57 |
HIST1H4A | interactor | 6 | 0.400 | 3.973 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
58 |
HIST4H4 | interactor | 10 | 0.400 | 13.142 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
59 |
HMBOX1 | interactor | 6 | 0.500 | 2.733 | DSBA (PF01323, IPR001853): DSBA-like thioredoxin domain DUF494 (PF04361, IPR007456): Protein of unknown function (DUF494) HNF-1_N (PF04814, IPR006899): Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
60 |
HNRNPH3 | protein found in more fusions | 5 | 0.500 | 0.956 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
61 |
HSP90AA1 | oncoprotein | 28 | 0.271 | 147.978 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
62 |
IK | interactor | 5 | 0.500 | 1.733 | Lsm_interact (PF05391, IPR008669): Lsm interaction motif RED_C (PF07807, IPR012492): RED-like protein C-terminal region RED_N (PF07808, IPR012916): RED-like protein N-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
63 |
IKZF3 | suppressor | 6 | 0.400 | 5.000 | C1_2 (PF03107, IPR004146): C1 domain Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger zf-C2H2_7 (PF15269): Zinc-finger |
64 |
IL4R | oncoprotein | 2 | 1.000 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL4Ra_N (PF09238, IPR015319): Interleukin-4 receptor alpha chain, N-terminal |
65 |
ING3 | suppressor | 8 | 0.714 | 4.233 | PHD (PF00628, IPR019787, SM00249): PHD-finger Rifin_STEVOR (PF02009, IPR002858): Rifin/stevor family ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding |
66 |
JADE1 | interactor | 3 | 0.667 | 1.000 | C1_2 (PF03107, IPR004146): C1 domain Glyco_hydro_57 (PF03065, IPR004300): Glycosyl hydrolase family 57 EPL1 (PF10513, IPR019542): Enhancer of polycomb-like eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5 PHD_2 (PF13831): PHD-finger zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain |
67 |
KLF4 | suppressor | 8 | 0.571 | 4.972 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
68 |
KRT40 | interactor | 6 | 0.400 | 7.000 | Filament (PF00038, IPR001664): Intermediate filament protein UPF0184 (PF03670, IPR022788): Uncharacterised protein family (UPF0184) |
69 |
KRTAP10-3 | interactor | 5 | 0.500 | 2.667 | Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein |
70 |
KRTAP10-9 | interactor | 4 | 0.667 | 1.000 | Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein |
71 |
LDHA | interactor | 8 | 0.524 | 5.767 | Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain |
72 |
LMNA | protein found in more fusions | 14 | 0.359 | 31.252 | Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) |
73 |
LONRF1 | interactor | 3 | 1.000 | 0 | LON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain DZR (PF12773, IPR025874): Double zinc ribbon TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) TPR_19 (PF14559): Tetratricopeptide repeat zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
74 |
LRIF1 | interactor | 18 | 0.191 | 86.804 | LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1 |
75 |
LRP1 | interactor | 4 | 0.833 | 0.667 | EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain SGL (PF08450, IPR013658): SMP-30/Gluconolaconase/LRE-like region TadE (PF07811, IPR012495): TadE-like protein Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_3 (PF12947, IPR024731): EGF domain FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site DUF5050 (PF16472, IPR032485): Domain of unknown function (DUF5050) |
76 |
LRRC42 | interactor | 3 | 1.000 | 0 | LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat |
77 |
MAD2L1BP | interactor | 6 | 0.400 | 4.700 | p31comet (PF06581, IPR009511): Mad1 and Cdc20-bound-Mad2 binding |
78 |
MAP3K1 | oncoprotein | 6 | 0.500 | 4.000 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Pkinase (PF00069, IPR000719): Protein kinase domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal |
79 |
MAPRE1 | oncoprotein | 10 | 0.278 | 25.000 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
80 |
MAX | suppressor | 10 | 0.472 | 10.360 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SlyX (PF04102, IPR007236): SlyX |
81 |
MBTD1 | interactor | 2 | 1.000 | 0 | C1_2 (PF03107, IPR004146): C1 domain MBT (PF02820, IPR004092, SM00561): mbt repeat zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif |
82 |
MDM2 | oncoprotein | 35 | 0.253 | 246.271 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
83 |
MEAF6 | interactor | 5 | 0.700 | 3.000 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) NuA4 (PF09340, IPR015418): Histone acetyltransferase subunit NuA4 |
84 |
MED23 | interactor | 12 | 0.424 | 22.310 | Med23 (PF11573, IPR021629): Mediator complex subunit 23 |
85 |
MORF4L1 | interactor | 16 | 0.305 | 57.605 | MRG (PF05712, IPR026541): MRG Fmp27_WPPW (PF10359, IPR019449): RNA pol II promoter Fmp27 protein domain Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
86 |
MRE11A | oncoprotein | 13 | 0.561 | 10.751 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase Mre11_DNA_bind (PF04152, IPR007281): Mre11 DNA-binding presumed domain |
87 |
MTUS2 | suppressor | 4 | 0.667 | 1.000 | DUF496 (PF04363, IPR007458): Protein of unknown function (DUF496) RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat FAM184 (PF15665): Family with sequence similarity 184, A and B |
88 |
MYB | oncoprotein | 5 | 0.700 | 0.679 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
89 |
MYC | oncoprotein | 27 | 0.274 | 152.241 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
90 |
MYOD1 | oncoprotein | 11 | 0.622 | 6.181 | Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Mfp-3 (PF04202, IPR007328): Foot protein 3 Myf5 (PF12232, IPR022032): Myogenic determination factor 5 |
91 |
NAP1L5 | interactor | 2 | 1.000 | 0 | NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) SspB (PF04386, IPR007481): Stringent starvation protein B Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) |
92 |
NBN | suppressor | 14 | 0.495 | 18.843 | FHA (PF00498, IPR000253, SM00240): FHA domain Nbs1_C (PF08599, IPR013908): DNA damage repair protein Nbs1 NIBRIN_BRCT_II (PF16508, IPR032429): Second BRCT domain on Nijmegen syndrome breakage protein RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
93 |
NDUFV2 | interactor | 1 | 0 | 0 | 2Fe-2S_thioredx (PF01257, IPR002023): Thioredoxin-like [2Fe-2S] ferredoxin |
94 |
NFKB1 | suppressor | 12 | 0.509 | 11.264 | Death (PF00531, IPR000488, SM00005): Death domain GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
95 |
NINL | interactor | 2 | 1.000 | 0 | PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat TBCA (PF02970, IPR004226): Tubulin binding cofactor A DUF2389 (PF09493, IPR012663): Tryptophan-rich protein (DUF2389) Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 EF-hand_1 (PF00036, IPR002048, SM00054): EF hand EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein FAM184 (PF15665): Family with sequence similarity 184, A and B TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain |
96 |
NMI | interactor | 6 | 0.500 | 2.956 | IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) |
97 |
NOD2 | interactor | 3 | 1.000 | 0 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain NACHT (PF05729): NACHT domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
98 |
NOTCH1 | suppressor | 14 | 0.372 | 32.258 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
99 |
NR1D2 | interactor | 4 | 0.500 | 2.667 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
100 |
NR3C1 | protein found in more fusions | 18 | 0.449 | 31.143 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
101 |
ODC1 | protein found in more fusions | 2 | 0 | 0 | Orn_Arg_deC_N (PF02784, IPR022644): Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC (PF00278, IPR022643): Pyridoxal-dependent decarboxylase, C-terminal sheet domain |
102 |
PCNA | oncoprotein | 18 | 0.316 | 52.125 | PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain |
103 |
PDCD5 | suppressor | 6 | 0.533 | 3.519 | dsDNA_bind (PF01984, IPR002836): Double-stranded DNA-binding domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region |
104 |
PHC2 | interactor | 5 | 0.667 | 1.167 | SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-CGNR (PF11706, IPR021005): CGNR zinc finger DUF4692 (PF15763, IPR031517): Domain of unknown function (DUF4692) PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2 |
105 |
PIH1D3 | interactor | 1 | 0 | 0 | PIH1 (PF08190, IPR012981): pre-RNA processing PIH1/Nop17 |
106 |
PLA2G4A | oncoprotein | 3 | 1.000 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain PLA2_B (PF01735, IPR002642): Lysophospholipase catalytic domain |
107 |
PLAGL2 | oncoprotein | 2 | 1.000 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
108 |
PLEKHA4 | interactor | 2 | 1.000 | 0 | IncA (PF04156, IPR007285): IncA protein PH (PF00169, IPR001849, SM00233): PH domain SlyX (PF04102, IPR007236): SlyX |
109 |
PML | suppressor | 25 | 0.304 | 107.092 | zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
110 |
POLE2 | interactor | 3 | 0.667 | 0.667 | DNA_pol_E_B (PF04042, IPR007185): DNA polymerase alpha/epsilon subunit B Dpoe2NT (PF12213, IPR024639): DNA polymerases epsilon N terminal |
111 |
POLR3F | interactor | 2 | 1.000 | 0 | RNA_pol_Rpc34 (PF05158, IPR007832): RNA polymerase Rpc34 subunit |
112 |
PPARG | suppressor | 16 | 0.419 | 35.785 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region |
113 |
PRKCE | suppressor | 4 | 1.000 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
114 |
PRKDC | protein found in more fusions | 20 | 0.421 | 38.444 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
115 |
PTPN4 | interactor | 1 | 0 | 0 | FA (PF08736, IPR014847): FERM adjacent (FA) FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase |
116 |
PTPRS | interactor | 1 | 0 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase Ig_3 (PF13927): Immunoglobulin domain |
117 |
RAD50 | interactor | 10 | 0.667 | 5.303 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region YscO (PF07321, IPR009929): Type III secretion protein YscO BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2 Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 DUF2703 (PF10865, IPR021219): Domain of unknown function (DUF2703) DUF3015 (PF11220, IPR021383): Protein of unknown function (DUF3015) AAA_13 (PF13166, IPR026866): AAA domain AAA_23 (PF13476): AAA domain SbcCD_C (PF13558): Putative exonuclease SbcCD, C subunit HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal DUF4795 (PF16043, IPR032013): Domain of unknown function (DUF4795) |
118 |
RBPJ | interactor | 6 | 0.600 | 2.102 | BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding TIG (PF01833, IPR002909): IPT/TIG domain |
119 |
RCHY1 | suppressor | 7 | 0.667 | 4.250 | C1_2 (PF03107, IPR004146): C1 domain zf-CHY (PF05495, IPR008913): CHY zinc finger zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zinc_ribbon_6 (PF14599): Zinc-ribbon |
120 |
RELA | oncoprotein | 27 | 0.354 | 104.745 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
121 |
RFLNB | interactor | 1 | 0 | 0 | FAM101 (PF15068, IPR028215): FAM101 family |
122 |
RGL2 | interactor | 1 | 0 | 0 | RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif |
123 |
RPL30 | interactor | 6 | 0.600 | 2.872 | NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3 |
124 |
RRM1 | oncoprotein | 5 | 0.667 | 0.486 | ATP-cone (PF03477, IPR005144): ATP cone domain Ribonuc_red_lgC (PF02867, IPR000788): Ribonucleotide reductase, barrel domain Ribonuc_red_lgN (PF00317, IPR013509): Ribonucleotide reductase, all-alpha domain |
125 |
SCFD1 | interactor | 1 | 0 | 0 | Sec1 (PF00995, IPR001619): Sec1 family |
126 |
SIAH2 | oncoprotein | 6 | 0.700 | 1.267 | Sina (PF03145, IPR018121): Seven in absentia protein family zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
127 |
SIRT1 | suppressor | 20 | 0.427 | 37.378 | DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
128 |
SNAPIN | interactor | 2 | 1.000 | 0 | Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin |
129 |
SOX5 | oncoprotein | 4 | 0.667 | 0.667 | HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box SOAR (PF16533, IPR032393): STIM1 Orai1-activating region MPS2 (PF17060, IPR031433): Monopolar spindle protein 2 |
130 |
SRCAP | interactor | 8 | 0.500 | 10.000 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif HSA (PF07529, IPR014012, SM00573): HSA RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DBINO (PF13892, IPR020838): DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
131 |
SRSF2 | oncoprotein | 8 | 0.524 | 6.400 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 Transformer (PF06495, IPR010519): Fruit fly transformer protein Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
132 |
SSX2IP | interactor | 7 | 0.333 | 7.833 | ZapB (PF06005, IPR009252): Cell division protein ZapB ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Surfac_D-trimer (PF09006, IPR015097): Lung surfactant protein D coiled-coil trimerisation ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding YqzH (PF14164, IPR025546): YqzH-like protein |
133 |
STAT3 | suppressor | 19 | 0.392 | 52.374 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
134 |
STX11 | interactor | 5 | 0.500 | 2.667 | KxDL (PF10241, IPR019371): Uncharacterized conserved protein Syntaxin (PF00804, IPR006011, SM00503): Syntaxin SNARE (PF05739, IPR000727, SM00397): SNARE domain |
135 |
SUMO1 | interactor | 11 | 0.422 | 17.790 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like |
136 |
SYN1 | protein found in more fusions | 2 | 0 | 0 | Synapsin_C (PF02750, IPR020898): Synapsin, ATP binding domain Synapsin_N (PF10581, IPR019736): Synapsin N-terminal DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) Synapsin (PF02078, IPR020897): Synapsin, N-terminal domain |
137 |
TMCC2 | protein found in more fusions | 3 | 1.000 | 0 | Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
138 |
TNK2 | interactor | 9 | 0.536 | 8.855 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal GTPase_binding (PF09027, IPR015116): GTPase binding Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6 UBA_4 (PF14555): UBA-like domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
139 |
TP53 | suppressor | 50 | 0.177 | 709.514 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
140 |
TP73 | suppressor | 11 | 0.600 | 7.112 | P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
141 |
TRIM23 | interactor | 5 | 0.833 | 0.667 | Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family FemAB (PF02388, IPR003447): FemAB family zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain |
142 |
TRIM27 | oncoprotein | 18 | 0.243 | 86.488 | IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
143 |
TRIM29 | protein found in more fusions | 5 | 0.667 | 1.667 | MIS13 (PF08202, IPR013218): Mis12-Mtw1 protein family TP2 (PF01254, IPR000678): Nuclear transition protein 2 zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger |
144 |
TRIM37 | oncoprotein | 6 | 0.400 | 4.119 | MATH (PF00917, IPR002083, SM00061): MATH domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) MRFAP1 (PF15155, IPR029254): MORF4 family-associated protein1 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain DUF5071 (PF16804, IPR031837): Domain of unknown function (DUF5071) |
145 |
TRIM68 | interactor | 2 | 1.000 | 0 | GAGA (PF09237, IPR015318): GAGA factor SPRY (PF00622, IPR003877, SM00449): SPRY domain DUF2259 (PF10016, IPR018725): Predicted secreted protein (DUF2259) zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
146 |
TRRAP | interactor | 16 | 0.375 | 45.356 | BALF1 (PF06861, IPR010677): BALF1 protein BP28CT (PF08146, IPR012954, SM01036): BP28CT (NUC211) domain DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) CLASP_N (PF12348, IPR024395): CLASP N terminal Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ (PF13513): HEAT-like repeat TRC8_N (PF13705, IPR025754): TRC8 N-terminal domain ACDC (PF14733, IPR028078): AP2-coincident C-terminal |
147 |
TUFT1 | interactor | 3 | 0.667 | 0.500 | USP8_interact (PF08941, IPR015036): USP8 interacting Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate 2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) |
148 |
UBTF | interactor | 3 | 1.000 | 0 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HMG_box_2 (PF09011, IPR009071): HMG-box domain HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box DUF4473 (PF14747, IPR027913): Domain of unknown function (DUF4473) HMG_box_5 (PF14887, IPR029215): HMG (high mobility group) box 5 |
149 |
UCKL1 | interactor | 1 | 0 | 0 | PRK (PF00485, IPR006083): Phosphoribulokinase / Uridine kinase family UPRTase (PF14681, IPR029057): Uracil phosphoribosyltransferase |
150 |
UHRF1 | interactor | 8 | 0.667 | 2.821 | PHD (PF00628, IPR019787, SM00249): PHD-finger SAD_SRA (PF02182, IPR003105, SM00466): SAD/SRA domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family TTD (PF12148, IPR021991): Tandem tudor domain within UHRF1 zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2 |
151 |
USP7 | oncoprotein | 20 | 0.304 | 67.522 | MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal |
152 |
VHL | suppressor | 17 | 0.375 | 43.621 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain |
153 |
YWHAG | protein found in more fusions | 11 | 0.400 | 18.967 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
154 |
ZBTB14 | interactor | 4 | 0.667 | 1.000 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
155 |
ZBTB33 | oncoprotein | 5 | 0.800 | 0.571 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain HD-ZIP_N (PF04618, IPR006712): HD-ZIP protein N terminus zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
156 |
ZBTB49 | interactor | 4 | 0.667 | 0.772 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type TORC_C (PF12886, IPR024785): Transducer of regulated CREB activity, C terminus zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
157 |
ZBTB7B | interactor | 4 | 1.000 | 0 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal GAGA (PF09237, IPR015318): GAGA factor SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
158 |
ZBTB8A | interactor | 5 | 0.833 | 0.500 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
159 |
ZEB1 | interactor | 6 | 0.467 | 1.724 | CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding GET2 (PF08690, IPR028143): GET complex subunit GET2 Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
160 |
ZNF24 | interactor | 6 | 0.600 | 4.700 | SCAN (PF02023, IPR003309, SM00431): SCAN domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain |
161 |
ZNF513 | protein found in more fusions | 2 | 0 | 0 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain DUF4379 (PF14311, IPR025487): Probable Zinc-ribbon domain Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain |