Statistic of PPI	Value(s)
The number of interactors (fusion and proteins)	161
The number (and %) of the onco-proteins	46 (28.57 %)
The number (and %) of the tumor suppressors	34 (21.12 %)
Total number of binary PPIs (saturation %)	853 (6.62 %)
The number (and %) of affected PPIs	160 (18.76 %)
The number of possible different fusions	36
PPI diameter	2
PPI radius	1
The average degree of PPI	9.540
Assortativity coefficient	-0.2743
The network average Clustering coefficient	0.514
The number (and %) of a zero Clustering coefficients	15 (9.32 %)
The number (and %) of a zero Betweenness Centrality	40 (24.84 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: KAT5	All fusions : BE731511;
Proteins found in more fusions	APP (see 4 fusions); SRSF2 (see 1 fusions); LMNA (see 3 fusions); YWHAG (see 1 fusions); HSP90AA1 (see 2 fusions); NR3C1 (see 8 fusions); TRIM27/MDM2 (see 1 fusions); HDAC7 (see 1 fusions); HNRNPH3 (see 1 fusions); CUL3 (see 1 fusions); NFKB1 (see 2 fusions); CREB1 (see 2 fusions); MAP3K1 (see 1 fusions); VHL (see 1 fusions); MYC (see 1 fusions); CREBBP (see 6 fusions); STAT3 (see 2 fusions); SYN1 (see 1 fusions); ARIH2 (see 2 fusions); MAPRE1 (see 1 fusions); PRKDC (see 3 fusions); ODC1 (see 1 fusions); RRM1 (see 1 fusions); SOX5 (see 1 fusions); MYOD1 (see 1 fusions); TMCC2 (see 3 fusions); ZNF513 (see 1 fusions); SIAH2 (see 1 fusions); EP300 (see 1 fusions); PCNA (see 1 fusions); PML (see 4 fusions); PRKCE (see 3 fusions); TP53 (see 3 fusions); GAPDH (see 2 fusions); TRIM29 (see 3 fusions);

List of the fusions

PPI for parental proteins: KAT5

All fusions

: BE731511;

Proteins found in more fusions

APP (see 4 fusions); SRSF2 (see 1 fusions); LMNA (see 3 fusions); YWHAG (see 1 fusions); HSP90AA1 (see 2 fusions); NR3C1 (see 8 fusions); TRIM27/MDM2 (see 1 fusions); HDAC7 (see 1 fusions); HNRNPH3 (see 1 fusions); CUL3 (see 1 fusions); NFKB1 (see 2 fusions); CREB1 (see 2 fusions); MAP3K1 (see 1 fusions); VHL (see 1 fusions); MYC (see 1 fusions); CREBBP (see 6 fusions); STAT3 (see 2 fusions); SYN1 (see 1 fusions); ARIH2 (see 2 fusions); MAPRE1 (see 1 fusions); PRKDC (see 3 fusions); ODC1 (see 1 fusions); RRM1 (see 1 fusions); SOX5 (see 1 fusions); MYOD1 (see 1 fusions); TMCC2 (see 3 fusions); ZNF513 (see 1 fusions); SIAH2 (see 1 fusions); EP300 (see 1 fusions); PCNA (see 1 fusions); PML (see 4 fusions); PRKCE (see 3 fusions); TP53 (see 3 fusions); GAPDH (see 2 fusions); TRIM29 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	BE731511	chimera	160	0.048	19617.695	MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
2	ANGPTL4	suppressor	4	0.833	0.222	SlyX (PF04102, IPR007236): SlyX Fibrinogen_C (PF00147, IPR002181, SM00186): Fibrinogen beta and gamma chains, C-terminal globular domain
3	APBB1	interactor	8	0.429	11.000	PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) WW (PF00397, IPR001202, SM00456): WW domain RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID)
4	APLP1	interactor	5	0.700	3.000	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus Ints3 (PF10189, IPR019333): Integrator complex subunit 3 APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
5	APLP2	interactor	2	1.000	0	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding ELM2 (PF01448, IPR000949): ELM2 domain Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain Usp (PF00582, IPR006016): Universal stress protein family YL1 (PF05764, IPR008895): YL1 nuclear protein APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
6	APP	protein found in more fusions	31	0.138	329.997	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
7	AR	oncoprotein	23	0.333	88.658	Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
8	ARIH2	protein found in more fusions	8	0.619	6.119	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zinc_ribbon_12 (PF11331, IPR021480): Probable zinc-ribbon domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING PRAS (PF15798, IPR026682): Proline-rich AKT1 substrate 1
9	ATF2	oncoprotein	21	0.295	77.337	bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
10	ATF3	suppressor	12	0.455	10.218	bZIP_1 (PF00170, IPR004827): bZIP transcription factor
11	ATM	suppressor	18	0.353	37.759	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
12	BARD1	suppressor	17	0.283	62.621	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
13	BCL3	oncoprotein	8	0.536	8.527	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies)
14	BMI1	oncoprotein	20	0.304	78.596	zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
15	C14orf169	interactor	3	1.000	0	Cupin_4 (PF08007, IPR003347): Cupin superfamily protein
16	C1orf174	interactor	2	1.000	0	UPF0688 (PF15772, IPR031530): UPF0688 family
17	CBX8	interactor	16	0.210	72.982	Atrophin-1 (PF03154, IPR002951): Atrophin-1 family Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain RBR (PF17208): RNA binding Region CBX7_C (PF17218): CBX family C-terminal motif
18	CCDC106	interactor	4	0.500	0.950	CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
19	CCDC136	suppressor	3	0.667	0.333	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus Com_YlbF (PF06133, IPR010368): Control of competence regulator ComK, YlbF/YmcA ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Sec34 (PF04136, IPR007265): Sec34-like family Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding FlxA (PF14282, IPR025577): FlxA-like protein PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
20	CCDC8	interactor	12	0.327	24.989	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA
21	CDK5RAP2	interactor	4	0.500	2.667	APG6 (PF04111, IPR007243): Autophagy protein Apg6 bZIP_1 (PF00170, IPR004827): bZIP transcription factor CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 DUF1993 (PF09351, IPR018531): Domain of unknown function (DUF1993) IncA (PF04156, IPR007285): IncA protein LPP (PF04728, IPR006817): Lipoprotein leucine-zipper Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein TSC22 (PF01166, IPR000580): TSC-22/dip/bun family Tup_N (PF08581, IPR013890): Tup N-terminal CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
22	CDKN2A	suppressor	14	0.418	28.261	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
23	CEBPA	suppressor	9	0.357	5.524	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
24	CREB1	oncoprotein	11	0.533	11.303	bZIP_1 (PF00170, IPR004827): bZIP transcription factor pKID (PF02173, IPR003102): pKID domain DUF4988 (PF16378, IPR032149): Domain of unknown function
25	CREBBP	suppressor	29	0.302	123.894	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
26	CRELD1	interactor	2	1.000	0	DUF326 (PF03860, IPR005560): Domain of Unknown Function (DUF326) EGF_2 (PF07974, IPR013111): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain DUF3456 (PF11938, IPR021852): TLR4 regulator and MIR-interacting MSAP cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
27	CSTF2	interactor	6	0.333	7.786	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
28	CUL3	protein found in more fusions	21	0.232	101.612	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
29	DLEU1	suppressor	2	1.000	0	DD_K (PF12121, IPR022731): Dermaseptin
30	DMAP1	interactor	13	0.397	32.191	DMAP1 (PF05499, IPR008468): DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like (PF16282, IPR032563): SANT/Myb-like domain of DAMP1
31	DNMT1	suppressor	11	0.444	12.674	BAH (PF01426, IPR001025, SM00439): BAH domain DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
32	DNTTIP2	interactor	5	0.500	1.983	BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II) E7 (PF00527, IPR000148): E7 protein, Early protein Fcf2 (PF08698, IPR014810): Fcf2 pre-rRNA processing FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
33	DUSP23	interactor	1	0	0	DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family PTPlike_phytase (PF14566): Inositol hexakisphosphate
34	E2F1	suppressor	13	0.449	15.265	Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
35	EFNA1	interactor	1	0	0	Ephrin (PF00812, IPR001799): Ephrin
36	EP300	oncoprotein	47	0.191	533.183	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
37	EP400	oncoprotein	12	0.515	17.926	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide DDHD (PF02862, IPR004177, SM01127): DDHD domain GN3L_Grn1 (PF08701, IPR014813): GNL3L/Grn1 putative GTPase HSA (PF07529, IPR014012, SM00573): HSA Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF3304 (PF11745, IPR021733): Protein of unknown function (DUF3304) DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381) Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch DUF3573 (PF12097, IPR021956): Protein of unknown function (DUF3573) Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain EP400_N (PF15790, IPR031575): E1A-binding protein p400, N-terminal
38	ESR1	suppressor	33	0.248	240.962	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
39	ESR2	suppressor	10	0.667	5.147	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ERbeta_N (PF12497, IPR021064): Estrogen receptor beta
40	FAM135B	interactor	1	0	0	DUF676 (PF05057, IPR007751): Putative serine esterase (DUF676) DUF3657 (PF12394, IPR022122): Protein of unknown function (DUF3657)
41	FAM173A	interactor	3	0.667	0.500	Methyltransf_23 (PF13489): Methyltransferase domain
42	FANCD2	oncoprotein	6	0.533	2.158	FancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nuclease
43	FOXO6	suppressor	3	1.000	0	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2 FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family
44	GADD45G	suppressor	7	0.476	6.158	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
45	GAPDH	oncoprotein	16	0.524	19.425	Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein
46	GEMIN7	interactor	1	0	0	Gemin7 (PF11095, IPR020338): Gem-associated protein 7 (Gemin7) SUZ-C (PF12901, IPR024642): SUZ-C motif
47	GET4	interactor	2	1.000	0	DUF410 (PF04190, IPR007317): Protein of unknown function (DUF410) Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
48	GMCL1	interactor	5	0.500	2.333	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
49	GOLGA2	interactor	8	0.464	11.122	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5
50	GSTO1	interactor	3	0.667	0.400	GST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
51	H2AFX	suppressor	19	0.333	63.353	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
52	H2AFZ	interactor	9	0.611	9.500	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
53	HABP4	interactor	2	1.000	0	HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
54	HAP1	interactor	12	0.273	36.333	HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
55	HDAC6	oncoprotein	14	0.295	27.312	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP) zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
56	HDAC7	protein found in more fusions	8	0.286	8.510	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO
57	HIST1H4A	interactor	6	0.400	3.973	CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
58	HIST4H4	interactor	10	0.400	13.142	CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
59	HMBOX1	interactor	6	0.500	2.733	DSBA (PF01323, IPR001853): DSBA-like thioredoxin domain DUF494 (PF04361, IPR007456): Protein of unknown function (DUF494) HNF-1_N (PF04814, IPR006899): Hepatocyte nuclear factor 1 (HNF-1), N terminus Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
60	HNRNPH3	protein found in more fusions	5	0.500	0.956	Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
61	HSP90AA1	oncoprotein	28	0.271	147.978	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
62	IK	interactor	5	0.500	1.733	Lsm_interact (PF05391, IPR008669): Lsm interaction motif RED_C (PF07807, IPR012492): RED-like protein C-terminal region RED_N (PF07808, IPR012916): RED-like protein N-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
63	IKZF3	suppressor	6	0.400	5.000	C1_2 (PF03107, IPR004146): C1 domain Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger zf-C2H2_7 (PF15269): Zinc-finger
64	IL4R	oncoprotein	2	1.000	0	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain IL4Ra_N (PF09238, IPR015319): Interleukin-4 receptor alpha chain, N-terminal
65	ING3	suppressor	8	0.714	4.233	PHD (PF00628, IPR019787, SM00249): PHD-finger Rifin_STEVOR (PF02009, IPR002858): Rifin/stevor family ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding
66	JADE1	interactor	3	0.667	1.000	C1_2 (PF03107, IPR004146): C1 domain Glyco_hydro_57 (PF03065, IPR004300): Glycosyl hydrolase family 57 EPL1 (PF10513, IPR019542): Enhancer of polycomb-like eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5 PHD_2 (PF13831): PHD-finger zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
67	KLF4	suppressor	8	0.571	4.972	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
68	KRT40	interactor	6	0.400	7.000	Filament (PF00038, IPR001664): Intermediate filament protein UPF0184 (PF03670, IPR022788): Uncharacterised protein family (UPF0184)
69	KRTAP10-3	interactor	5	0.500	2.667	Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
70	KRTAP10-9	interactor	4	0.667	1.000	Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
71	LDHA	interactor	8	0.524	5.767	Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
72	LMNA	protein found in more fusions	14	0.359	31.252	Filament (PF00038, IPR001664): Intermediate filament protein LTD (PF00932, IPR001322): Lamin Tail Domain Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
73	LONRF1	interactor	3	1.000	0	LON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain DZR (PF12773, IPR025874): Double zinc ribbon TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) TPR_19 (PF14559): Tetratricopeptide repeat zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
74	LRIF1	interactor	18	0.191	86.804	LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1
75	LRP1	interactor	4	0.833	0.667	EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain SGL (PF08450, IPR013658): SMP-30/Gluconolaconase/LRE-like region TadE (PF07811, IPR012495): TadE-like protein Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_3 (PF12947, IPR024731): EGF domain FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site DUF5050 (PF16472, IPR032485): Domain of unknown function (DUF5050)
76	LRRC42	interactor	3	1.000	0	LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat
77	MAD2L1BP	interactor	6	0.400	4.700	p31comet (PF06581, IPR009511): Mad1 and Cdc20-bound-Mad2 binding
78	MAP3K1	oncoprotein	6	0.500	4.000	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Pkinase (PF00069, IPR000719): Protein kinase domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
79	MAPRE1	oncoprotein	10	0.278	25.000	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
80	MAX	suppressor	10	0.472	10.360	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SlyX (PF04102, IPR007236): SlyX
81	MBTD1	interactor	2	1.000	0	C1_2 (PF03107, IPR004146): C1 domain MBT (PF02820, IPR004092, SM00561): mbt repeat zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif
82	MDM2	oncoprotein	35	0.253	246.271	Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
83	MEAF6	interactor	5	0.700	3.000	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) NuA4 (PF09340, IPR015418): Histone acetyltransferase subunit NuA4
84	MED23	interactor	12	0.424	22.310	Med23 (PF11573, IPR021629): Mediator complex subunit 23
85	MORF4L1	interactor	16	0.305	57.605	MRG (PF05712, IPR026541): MRG Fmp27_WPPW (PF10359, IPR019449): RNA pol II promoter Fmp27 protein domain Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
86	MRE11A	oncoprotein	13	0.561	10.751	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase Mre11_DNA_bind (PF04152, IPR007281): Mre11 DNA-binding presumed domain
87	MTUS2	suppressor	4	0.667	1.000	DUF496 (PF04363, IPR007458): Protein of unknown function (DUF496) RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat FAM184 (PF15665): Family with sequence similarity 184, A and B
88	MYB	oncoprotein	5	0.700	0.679	Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
89	MYC	oncoprotein	27	0.274	152.241	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
90	MYOD1	oncoprotein	11	0.622	6.181	Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Mfp-3 (PF04202, IPR007328): Foot protein 3 Myf5 (PF12232, IPR022032): Myogenic determination factor 5
91	NAP1L5	interactor	2	1.000	0	NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) SspB (PF04386, IPR007481): Stringent starvation protein B Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
92	NBN	suppressor	14	0.495	18.843	FHA (PF00498, IPR000253, SM00240): FHA domain Nbs1_C (PF08599, IPR013908): DNA damage repair protein Nbs1 NIBRIN_BRCT_II (PF16508, IPR032429): Second BRCT domain on Nijmegen syndrome breakage protein RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
93	NDUFV2	interactor	1	0	0	2Fe-2S_thioredx (PF01257, IPR002023): Thioredoxin-like [2Fe-2S] ferredoxin
94	NFKB1	suppressor	12	0.509	11.264	Death (PF00531, IPR000488, SM00005): Death domain GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
95	NINL	interactor	2	1.000	0	PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat TBCA (PF02970, IPR004226): Tubulin binding cofactor A DUF2389 (PF09493, IPR012663): Tryptophan-rich protein (DUF2389) Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 EF-hand_1 (PF00036, IPR002048, SM00054): EF hand EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein FAM184 (PF15665): Family with sequence similarity 184, A and B TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
96	NMI	interactor	6	0.500	2.956	IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
97	NOD2	interactor	3	1.000	0	CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain NACHT (PF05729): NACHT domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat
98	NOTCH1	suppressor	14	0.372	32.258	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
99	NR1D2	interactor	4	0.500	2.667	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
100	NR3C1	protein found in more fusions	18	0.449	31.143	GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
101	ODC1	protein found in more fusions	2	0	0	Orn_Arg_deC_N (PF02784, IPR022644): Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC (PF00278, IPR022643): Pyridoxal-dependent decarboxylase, C-terminal sheet domain
102	PCNA	oncoprotein	18	0.316	52.125	PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
103	PDCD5	suppressor	6	0.533	3.519	dsDNA_bind (PF01984, IPR002836): Double-stranded DNA-binding domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
104	PHC2	interactor	5	0.667	1.167	SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-CGNR (PF11706, IPR021005): CGNR zinc finger DUF4692 (PF15763, IPR031517): Domain of unknown function (DUF4692) PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
105	PIH1D3	interactor	1	0	0	PIH1 (PF08190, IPR012981): pre-RNA processing PIH1/Nop17
106	PLA2G4A	oncoprotein	3	1.000	0	C2 (PF00168, IPR000008, SM00239): C2 domain PLA2_B (PF01735, IPR002642): Lysophospholipase catalytic domain
107	PLAGL2	oncoprotein	2	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
108	PLEKHA4	interactor	2	1.000	0	IncA (PF04156, IPR007285): IncA protein PH (PF00169, IPR001849, SM00233): PH domain SlyX (PF04102, IPR007236): SlyX
109	PML	suppressor	25	0.304	107.092	zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
110	POLE2	interactor	3	0.667	0.667	DNA_pol_E_B (PF04042, IPR007185): DNA polymerase alpha/epsilon subunit B Dpoe2NT (PF12213, IPR024639): DNA polymerases epsilon N terminal
111	POLR3F	interactor	2	1.000	0	RNA_pol_Rpc34 (PF05158, IPR007832): RNA polymerase Rpc34 subunit
112	PPARG	suppressor	16	0.419	35.785	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region
113	PRKCE	suppressor	4	1.000	0	C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
114	PRKDC	protein found in more fusions	20	0.421	38.444	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
115	PTPN4	interactor	1	0	0	FA (PF08736, IPR014847): FERM adjacent (FA) FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
116	PTPRS	interactor	1	0	0	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase Ig_3 (PF13927): Immunoglobulin domain
117	RAD50	interactor	10	0.667	5.303	DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region YscO (PF07321, IPR009929): Type III secretion protein YscO BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2 Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 DUF2703 (PF10865, IPR021219): Domain of unknown function (DUF2703) DUF3015 (PF11220, IPR021383): Protein of unknown function (DUF3015) AAA_13 (PF13166, IPR026866): AAA domain AAA_23 (PF13476): AAA domain SbcCD_C (PF13558): Putative exonuclease SbcCD, C subunit HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal DUF4795 (PF16043, IPR032013): Domain of unknown function (DUF4795)
118	RBPJ	interactor	6	0.600	2.102	BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding TIG (PF01833, IPR002909): IPT/TIG domain
119	RCHY1	suppressor	7	0.667	4.250	C1_2 (PF03107, IPR004146): C1 domain zf-CHY (PF05495, IPR008913): CHY zinc finger zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zinc_ribbon_6 (PF14599): Zinc-ribbon
120	RELA	oncoprotein	27	0.354	104.745	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
121	RFLNB	interactor	1	0	0	FAM101 (PF15068, IPR028215): FAM101 family
122	RGL2	interactor	1	0	0	RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
123	RPL30	interactor	6	0.600	2.872	NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
124	RRM1	oncoprotein	5	0.667	0.486	ATP-cone (PF03477, IPR005144): ATP cone domain Ribonuc_red_lgC (PF02867, IPR000788): Ribonucleotide reductase, barrel domain Ribonuc_red_lgN (PF00317, IPR013509): Ribonucleotide reductase, all-alpha domain
125	SCFD1	interactor	1	0	0	Sec1 (PF00995, IPR001619): Sec1 family
126	SIAH2	oncoprotein	6	0.700	1.267	Sina (PF03145, IPR018121): Seven in absentia protein family zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
127	SIRT1	suppressor	20	0.427	37.378	DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
128	SNAPIN	interactor	2	1.000	0	Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
129	SOX5	oncoprotein	4	0.667	0.667	HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box SOAR (PF16533, IPR032393): STIM1 Orai1-activating region MPS2 (PF17060, IPR031433): Monopolar spindle protein 2
130	SRCAP	interactor	8	0.500	10.000	AT_hook (PF02178, IPR017956, SM00384): AT hook motif HSA (PF07529, IPR014012, SM00573): HSA RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DBINO (PF13892, IPR020838): DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
131	SRSF2	oncoprotein	8	0.524	6.400	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 Transformer (PF06495, IPR010519): Fruit fly transformer protein Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
132	SSX2IP	interactor	7	0.333	7.833	ZapB (PF06005, IPR009252): Cell division protein ZapB ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Surfac_D-trimer (PF09006, IPR015097): Lung surfactant protein D coiled-coil trimerisation ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding YqzH (PF14164, IPR025546): YqzH-like protein
133	STAT3	suppressor	19	0.392	52.374	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
134	STX11	interactor	5	0.500	2.667	KxDL (PF10241, IPR019371): Uncharacterized conserved protein Syntaxin (PF00804, IPR006011, SM00503): Syntaxin SNARE (PF05739, IPR000727, SM00397): SNARE domain
135	SUMO1	interactor	11	0.422	17.790	Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
136	SYN1	protein found in more fusions	2	0	0	Synapsin_C (PF02750, IPR020898): Synapsin, ATP binding domain Synapsin_N (PF10581, IPR019736): Synapsin N-terminal DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) Synapsin (PF02078, IPR020897): Synapsin, N-terminal domain
137	TMCC2	protein found in more fusions	3	1.000	0	Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
138	TNK2	interactor	9	0.536	8.855	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal GTPase_binding (PF09027, IPR015116): GTPase binding Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6 UBA_4 (PF14555): UBA-like domain SH3_9 (PF14604, IPR001452): Variant SH3 domain
139	TP53	suppressor	50	0.177	709.514	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
140	TP73	suppressor	11	0.600	7.112	P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
141	TRIM23	interactor	5	0.833	0.667	Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family FemAB (PF02388, IPR003447): FemAB family zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
142	TRIM27	oncoprotein	18	0.243	86.488	IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
143	TRIM29	protein found in more fusions	5	0.667	1.667	MIS13 (PF08202, IPR013218): Mis12-Mtw1 protein family TP2 (PF01254, IPR000678): Nuclear transition protein 2 zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
144	TRIM37	oncoprotein	6	0.400	4.119	MATH (PF00917, IPR002083, SM00061): MATH domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) MRFAP1 (PF15155, IPR029254): MORF4 family-associated protein1 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain DUF5071 (PF16804, IPR031837): Domain of unknown function (DUF5071)
145	TRIM68	interactor	2	1.000	0	GAGA (PF09237, IPR015318): GAGA factor SPRY (PF00622, IPR003877, SM00449): SPRY domain DUF2259 (PF10016, IPR018725): Predicted secreted protein (DUF2259) zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
146	TRRAP	interactor	16	0.375	45.356	BALF1 (PF06861, IPR010677): BALF1 protein BP28CT (PF08146, IPR012954, SM01036): BP28CT (NUC211) domain DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) CLASP_N (PF12348, IPR024395): CLASP N terminal Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_EZ (PF13513): HEAT-like repeat TRC8_N (PF13705, IPR025754): TRC8 N-terminal domain ACDC (PF14733, IPR028078): AP2-coincident C-terminal
147	TUFT1	interactor	3	0.667	0.500	USP8_interact (PF08941, IPR015036): USP8 interacting Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate 2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
148	UBTF	interactor	3	1.000	0	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HMG_box_2 (PF09011, IPR009071): HMG-box domain HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box DUF4473 (PF14747, IPR027913): Domain of unknown function (DUF4473) HMG_box_5 (PF14887, IPR029215): HMG (high mobility group) box 5
149	UCKL1	interactor	1	0	0	PRK (PF00485, IPR006083): Phosphoribulokinase / Uridine kinase family UPRTase (PF14681, IPR029057): Uracil phosphoribosyltransferase
150	UHRF1	interactor	8	0.667	2.821	PHD (PF00628, IPR019787, SM00249): PHD-finger SAD_SRA (PF02182, IPR003105, SM00466): SAD/SRA domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family TTD (PF12148, IPR021991): Tandem tudor domain within UHRF1 zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
151	USP7	oncoprotein	20	0.304	67.522	MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
152	VHL	suppressor	17	0.375	43.621	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain
153	YWHAG	protein found in more fusions	11	0.400	18.967	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
154	ZBTB14	interactor	4	0.667	1.000	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
155	ZBTB33	oncoprotein	5	0.800	0.571	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain HD-ZIP_N (PF04618, IPR006712): HD-ZIP protein N terminus zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
156	ZBTB49	interactor	4	0.667	0.772	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type TORC_C (PF12886, IPR024785): Transducer of regulated CREB activity, C terminus zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
157	ZBTB7B	interactor	4	1.000	0	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal GAGA (PF09237, IPR015318): GAGA factor SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
158	ZBTB8A	interactor	5	0.833	0.500	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
159	ZEB1	interactor	6	0.467	1.724	CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding GET2 (PF08690, IPR028143): GET complex subunit GET2 Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
160	ZNF24	interactor	6	0.600	4.700	SCAN (PF02023, IPR003309, SM00431): SCAN domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
161	ZNF513	protein found in more fusions	2	0	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain DUF4379 (PF14311, IPR025487): Probable Zinc-ribbon domain Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain

B a c k t o T o p ⇑

List of missing interactors

#	Name	Type	Domains (Pfam, InterPro, SMART): description	Fusion(s)
1	ACTA1	interactor	Actin (PF00022, IPR004000, SM00268): Actin
2	ACTB	oncoprotein	Actin (PF00022, IPR004000, SM00268): Actin
3	ACTG1	interactor	Actin (PF00022, IPR004000, SM00268): Actin
4	ACTG2	interactor	Actin (PF00022, IPR004000, SM00268): Actin
5	ACTL6A	interactor	Actin (PF00022, IPR004000, SM00268): Actin
6	BRCA1	suppressor	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
7	BRD8	interactor	Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
8	CCT7	interactor	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
9	CDC42	oncoprotein	Ras (PF00071, IPR001806, SM00173): Ras family
10	CDK1	oncoprotein	Pkinase (PF00069, IPR000719): Protein kinase domain
11	EDNRA	interactor	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
12	EPC1	interactor	E_Pc_C (PF06752, IPR009607): Enhancer of Polycomb C-terminus EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
13	EPC2	interactor	E_Pc_C (PF06752, IPR009607): Enhancer of Polycomb C-terminus EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
14	ETV6	suppressor	Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
15	FOXP3	suppressor	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
16	FOXR1	interactor	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
17	FOXR2	interactor	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
18	GMCL1P1	interactor	NA
19	HDAC1	suppressor	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
20	HDAC3	suppressor	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
21	HDGF	interactor	PWWP (PF00855, IPR000313, SM00293): PWWP domain
22	HINT1	suppressor	HIT (PF01230, IPR001310): HIT domain
23	HIST1H2BA	interactor	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
24	HIST1H3A	interactor	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
25	HIST2H3C	interactor	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
26	HIST3H3	interactor	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
27	IL9R	interactor	NA
28	KAT5	parental protein	MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
29	LZTS2	suppressor	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127) Fez1 (PF06818): Fez1 ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
30	MDFI	interactor	MDFI (PF15316, IPR026134): MyoD family inhibitor
31	MEOX2	interactor	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
32	MORF4L2	interactor	MRG (PF05712, IPR026541): MRG
33	MRGBP	interactor	Eaf7 (PF07904, IPR012423): Chromatin modification-related protein EAF7
34	NDUFA4L2	interactor	B12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
35	OGFOD2	interactor	NA
36	PLAC1	interactor	Paired_CXXCH_1 (PF09699, IPR010177): Doubled CXXCH motif (Paired_CXXCH_1)
37	RB1	suppressor	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
38	RRM2	interactor	Ribonuc_red_sm (PF00268, IPR000358): Ribonucleotide reductase, small chain
39	RUVBL1	oncoprotein	TIP49 (PF06068, IPR010339): TIP49 C-terminus
40	RUVBL2	oncoprotein	TIP49 (PF06068, IPR010339): TIP49 C-terminus
41	SAT1	interactor	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
42	SENP6	interactor	Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
43	SNRPD2	interactor	LSM (PF01423, IPR001163): LSM domain
44	SRF	interactor	SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain)
45	TBX5	suppressor	T-box (PF00907, IPR001699, SM00425): T-box
46	TNNT1	interactor	Troponin (PF00992, IPR001978): Troponin DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050)
47	TRIB3	interactor	Pkinase (PF00069, IPR000719): Protein kinase domain
48	UBE2I	interactor	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
49	VPS72	interactor	YL1 (PF05764, IPR008895): YL1 nuclear protein YL1_C (PF08265, IPR013272, SM00993): YL1 nuclear protein C-terminal domain
50	YEATS4	interactor	YEATS (PF03366, IPR005033): YEATS family SOGA (PF11365, IPR027881): Protein SOGA

B a c k t o T o p ⇑

Fusion ID: Protein names:	BE731511
Level of PPIs:	or Upload text file:	Update repository

Visible interactions:	all	affected	independent (normal)	missing	nothing (blank)
Chimeric state:	ordinary fusion	big fusion

Examples	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
Layout Tree Circle Radial Force Directed Preset
Export graph PDF file SVG file SIF file XML file GraphML file

Find Fusion Network

Visualization interactions

Statistics and Network structure information

List of the fusions

List of active interactors

List of missing interactors