Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: BC053662 is the fusion of parental proteins FAM178B, PRRG1 (from a repository: Mon May 14 12:30:07 2018)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)6
The number (and %) of the onco-proteins2 (33.33 %)
The number (and %) of the tumor suppressors3 (50.00 %)
Total number of binary PPIs (saturation %)10 (66.67 %)
The number (and %) of affected PPIs5 (50.00 %)
The number of possible different fusions3
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.4472
The network average Clustering coefficient0.350
The number (and %) of a zero Clustering coefficients3 (50.00 %)
The number (and %) of a zero Betweenness Centrality5 (83.33 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: PRRG1,FAM178B All fusions
: BC053662;
Proteins found in more fusions NEDD4L (see 3 fusions); NEDD4 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 BC053662chimera50.10018.000Ferritin (PF00210, IPR008331): Ferritin-like domain
Gla (PF00594, IPR000294, SM00069): Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
RCR (PF12273, IPR020999): Chitin synthesis regulation, resistance to Congo red
CCSMST1 (PF15013, IPR029160): CCSMST1 family
TMEM252 (PF15664, IPR031363): Transmembrane protein 252 family
2 ELAVL1oncoprotein31.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
3 FBXO25suppressor100Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
4 LRSAM1interactor200Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
5 NEDD4suppressor200Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
6 NEDD4Lsuppressor31.0000WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 FAM178Bparental proteinFAM178 (PF14816, IPR026161): Family of unknown function, FAM178
2 PRRG1parental proteinGla (PF00594, IPR000294, SM00069): Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
RCR (PF12273, IPR020999): Chitin synthesis regulation, resistance to Congo red
TMEM252 (PF15664, IPR031363): Transmembrane protein 252 family

B a c k    t o    T o p ⇑