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Fusion ID: Protein names:	AW901367
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Visualization interactions

Cytoscape Web for: AW901367 is the fusion of parental proteins TATDN2, CACNA1G (from a repository: Fri Mar 17 03:56:23 2017)

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Statistics and Network structure information

Statistic of PPI	Value(s)
The number of interactors (fusion and proteins)	4
The number (and %) of the onco-proteins	1 (25.00 %)
The number (and %) of the tumor suppressors	1 (25.00 %)
Total number of binary PPIs (saturation %)	6 (100.00 %)
The number (and %) of affected PPIs	3 (50.00 %)
The number of possible different fusions	2
PPI diameter	2
PPI radius	1
The average degree of PPI	1.500
Assortativity coefficient	0
The network average Clustering coefficient	0.000
The number (and %) of a zero Clustering coefficients	4 (100.00 %)
The number (and %) of a zero Betweenness Centrality	3 (75.00 %)

ACTIVE INTERACTORS

MISSING INTERACTORS

List of the fusions
PPI for parental proteins: CACNA1G,TATDN2	All fusions : AW901367;
Proteins found in more fusions	RANBP9 (see 2 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	AW901367	chimera	3	0	6.000	Ion_trans (PF00520, IPR005821): Ion transport protein MscL (PF01741, IPR001185): Large-conductance mechanosensitive channel, MscL SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region DUF3678 (PF12435, IPR022146): Protein of unknown function (DUF3678) SieB (PF14163, IPR025982): Super-infection exclusion protein B
2	FBXW11	interactor	2	0	0	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
3	RANBP9	suppressor	2	0	0	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator LisH (PF08513, IPR013720, SM00667): LisH SPRY (PF00622, IPR003877, SM00449): SPRY domain CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
4	UBQLN4	interactor	2	0	0	CRF (PF00473, IPR000187, SM00039): Corticotropin-releasing factor family DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Arm_2 (PF04826, IPR006911): Armadillo-like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B partial_CstF (PF15861, IPR031721): Partial cleavage stimulation factor domain

B a c k t o T o p ⇑

List of missing interactors

#	Name	Type	Domains (Pfam, InterPro, SMART): description	Fusion(s)
1	BRCA1	suppressor	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
2	CACNA1G	parental protein	Ion_trans (PF00520, IPR005821): Ion transport protein MscL (PF01741, IPR001185): Large-conductance mechanosensitive channel, MscL SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region DUF3678 (PF12435, IPR022146): Protein of unknown function (DUF3678) SieB (PF14163, IPR025982): Super-infection exclusion protein B
3	CCNJL	interactor	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
4	MOV10	interactor	AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain
5	MRPL4	interactor	Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
6	NXF1	interactor	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
7	PLAUR	oncoprotein	Toxin_1 (PF00087, IPR003571): Snake toxin UPAR_LY6 (PF00021, IPR001526): u-PAR/Ly-6 domain
8	SPACA1	interactor	DUF912 (PF06024, IPR009261): Nucleopolyhedrovirus protein of unknown function (DUF912) PRIMA1 (PF16101): Proline-rich membrane anchor 1
9	TATDN2	parental protein	TatD_DNase (PF01026, IPR001130): TatD related DNase

B a c k t o T o p ⇑