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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: AW901367 is the fusion of parental proteins TATDN2, CACNA1G (from a repository: Fri Mar 17 03:56:23 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)4
The number (and %) of the onco-proteins1 (25.00 %)
The number (and %) of the tumor suppressors1 (25.00 %)
Total number of binary PPIs (saturation %)6 (100.00 %)
The number (and %) of affected PPIs3 (50.00 %)
The number of possible different fusions2
PPI diameter2
PPI radius1
The average degree of PPI1.500
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients4 (100.00 %)
The number (and %) of a zero Betweenness Centrality3 (75.00 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: CACNA1G,TATDN2 All fusions
: AW901367;
Proteins found in more fusions RANBP9 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AW901367chimera306.000Ion_trans (PF00520, IPR005821): Ion transport protein
MscL (PF01741, IPR001185): Large-conductance mechanosensitive channel, MscL
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
DUF3678 (PF12435, IPR022146): Protein of unknown function (DUF3678)
SieB (PF14163, IPR025982): Super-infection exclusion protein B
2 FBXW11interactor200WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
3 RANBP9suppressor200Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
LisH (PF08513, IPR013720, SM00667): LisH
SPRY (PF00622, IPR003877, SM00449): SPRY domain
CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
4 UBQLN4interactor200CRF (PF00473, IPR000187, SM00039): Corticotropin-releasing factor family
DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
Arm_2 (PF04826, IPR006911): Armadillo-like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
partial_CstF (PF15861, IPR031721): Partial cleavage stimulation factor domain

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 BRCA1suppressorBRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
2 CACNA1Gparental proteinIon_trans (PF00520, IPR005821): Ion transport protein
MscL (PF01741, IPR001185): Large-conductance mechanosensitive channel, MscL
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
DUF3678 (PF12435, IPR022146): Protein of unknown function (DUF3678)
SieB (PF14163, IPR025982): Super-infection exclusion protein B
3 CCNJLinteractorCyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
4 MOV10interactorAAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
5 MRPL4interactorRibosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
6 NXF1interactorNTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
7 PLAURoncoproteinToxin_1 (PF00087, IPR003571): Snake toxin
UPAR_LY6 (PF00021, IPR001526): u-PAR/Ly-6 domain
8 SPACA1interactorDUF912 (PF06024, IPR009261): Nucleopolyhedrovirus protein of unknown function (DUF912)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
9 TATDN2parental proteinTatD_DNase (PF01026, IPR001130): TatD related DNase

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