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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: AW888966 is the fusion of parental proteins SLC1A3, IFITM1 (from a repository: Mon May 27 13:13:57 2019)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)4
The number (and %) of the onco-proteins2 (50.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)4 (66.67 %)
The number (and %) of affected PPIs3 (75.00 %)
The number of possible different fusions1
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.3333
The network average Clustering coefficient0.583
The number (and %) of a zero Clustering coefficients1 (25.00 %)
The number (and %) of a zero Betweenness Centrality3 (75.00 %)


List of the fusions

PPI for parental proteins: SLC1A3,IFITM1 All fusions
: AW888966;
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 AW888966chimera30.3334.000CD225 (PF04505, IPR007593): Interferon-induced transmembrane protein
2 ABHD16Ainteractor100Abhydrolase_1 (PF00561, IPR000073): alpha/beta hydrolase fold
Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family
3 CD19interactor21.0000V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
4 CR2oncoprotein21.0000C_tripleX (PF02363, IPR003341): Cysteine rich repeat
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
TIL (PF01826, IPR002919): Trypsin Inhibitor like cysteine rich domain
Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 CD81interactorTetraspannin (PF00335, IPR018499): Tetraspanin family
2 CUL3interactorCullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
3 IFITM1parental proteinCD225 (PF04505, IPR007593): Interferon-induced transmembrane protein
4 LGALS3oncoproteinGal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
5 SLC1A3parental proteinSDF (PF00375, IPR001991): Sodium:dicarboxylate symporter family
6 TCTN3interactorDUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
7 TMEM17interactorTransmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
8 ZDHHC17interactorzf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)

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