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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: AW405039 is the fusion of parental proteins B2M, IKZF1 (from a repository: Tue Dec 6 13:15:50 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)21
The number (and %) of the onco-proteins12 (57.14 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)59 (28.10 %)
The number (and %) of affected PPIs20 (33.90 %)
The number of possible different fusions7
PPI diameter2
PPI radius1
The average degree of PPI4.762
Assortativity coefficient-0.2745
The network average Clustering coefficient0.681
The number (and %) of a zero Clustering coefficients2 (9.52 %)
The number (and %) of a zero Betweenness Centrality8 (38.10 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: B2M,IKZF1 All fusions
: AW405039;
Proteins found in more fusions CALR (see 6 fusions); HLA-B (see 2 fusions); ERBB3 (see 2 fusions); A2M (see 2 fusions); GRB2 (see 1 fusions); HLA-B/HLA-C (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AW405039chimera200.158264.900C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
2 A2Mprotein found in more fusions40.6671.000A2M (PF00207, IPR001599): Alpha-2-macroglobulin family
A2M_comp (PF07678, IPR011626): A-macroglobulin complement component
A2M_N (PF01835, IPR002890): MG2 domain
A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region
A2M_recep (PF07677, IPR009048): A-macroglobulin receptor
MP (PF01107, IPR028919): Viral movement protein (MP)
SVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA)
Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region
3 BAG6interactor31.0000DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
4 CALRoncoprotein70.6005.000Calreticulin (PF00262, IPR001580): Calreticulin family
DDHD (PF02862, IPR004177, SM01127): DDHD domain
5 CD1Binteractor21.0000C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
MLANA (PF14991, IPR029242): Protein melan-A
MHC_I_3 (PF16497, IPR011161): MHC-I family domain
6 CD1Dinteractor21.0000Kelch_2 (PF07646, IPR011498): Kelch motif
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
MHC_I_3 (PF16497, IPR011161): MHC-I family domain
7 CRYABoncoprotein31.0000Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
8 CXCR4interactor21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
COX2_TM (PF02790, IPR011759): Cytochrome C oxidase subunit II, transmembrane domain
CXCR4_N (PF12109, IPR022726): CXCR4 Chemokine receptor N terminal
9 ERBB3oncoprotein50.6672.000Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
10 GRB2oncoprotein40.6671.000SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
11 HFEoncoprotein100DUF912 (PF06024, IPR009261): Nucleopolyhedrovirus protein of unknown function (DUF912)
MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
12 HLA-Aoncoprotein110.40028.900DUF202 (PF02656, IPR003807): Domain of unknown function (DUF202)
MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
13 HLA-Boncoprotein70.6005.333MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
14 HLA-Cprotein found in more fusions70.7332.500Marek_A (PF02124, IPR001038): Marek's disease glycoprotein A
MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
15 HLA-Einteractor70.6195.233MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
AA_permease_C (PF13906, IPR029485): C-terminus of AA_permease
16 HLA-Finteractor31.0000MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
Ig_3 (PF13927): Immunoglobulin domain
17 HSPB2interactor40.6671.000Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
18 MAPK15interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
19 TAP1oncoprotein50.9000.400ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
20 TAP2oncoprotein60.7332.333ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
21 TAPBPinteractor50.9000.400C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 AENinteractorRNase_T (PF00929, IPR013520): Exonuclease
2 ALKBH3interactor2OG-FeII_Oxy_2 (PF13532, IPR027450): 2OG-Fe(II) oxygenase superfamily
3 ANKRD11interactorDUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Pap_E4 (PF02711, IPR003861): E4 protein
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
AAA_11 (PF13086): AAA domain
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
4 AP1M1interactorAdap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
5 AP2M1interactorAdap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
6 ARMC7interactorAdaptin_N (PF01602, IPR002553): Adaptin N terminal region
Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
7 B2Mparental proteinC1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
8 BYSLinteractorBystin (PF05291, IPR007955): Bystin
MEA1 (PF06910, IPR009685): Male enhanced antigen 1 (MEA1)
9 C19orf66interactorUPF0515 (PF15135, IPR026795): Uncharacterised protein UPF0515
10 C1orf109interactorCK2S (PF15011, IPR029159): Casein Kinase 2 substrate
11 C1orf174interactorUPF0688 (PF15772, IPR031530): UPF0688 family
12 C8orf33interactorDUF4615 (PF15393, IPR029274): Domain of unknown function (DUF4615)
13 CBX8interactorAtrophin-1 (PF03154, IPR002951): Atrophin-1 family
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
RBR (PF17208): RNA binding Region
CBX7_C (PF17218): CBX family C-terminal motif
14 CDK2AP2interactorCDK2AP (PF09806, IPR019187): Cyclin-dependent kinase 2-associated protein
15 CEP57L1interactorCep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
XhlA (PF10779, IPR019715): Haemolysin XhlA
YqzE (PF14038, IPR025622): YqzE-like protein
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
16 CHD3oncoproteinCHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
FAM176 (PF14851): FAM176 family
17 CHD4oncoproteinCDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
FAM176 (PF14851): FAM176 family
Coilin_N (PF15862, IPR031722): Coilin N-terminus
18 CKS1BoncoproteinCKS (PF01111, IPR000789, SM01084): Cyclin-dependent kinase regulatory subunit
19 CRBNinteractorLON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain
Yippee-Mis18 (PF03226, IPR004910): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly
20 CSNK1G1interactorPkinase (PF00069, IPR000719): Protein kinase domain
CK1gamma_C (PF12605, IPR022247): Casein kinase 1 gamma C terminal
21 CTBP1interactor2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
22 CTBP2interactor2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
23 DCXinteractorDCX (PF03607, IPR003533, SM00537): Doublecortin
MGC-24 (PF05283, IPR007947): Multi-glycosylated core protein 24 (MGC-24), sialomucin
24 DDX6oncoproteinDEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
25 DYRK2interactorPkinase (PF00069, IPR000719): Protein kinase domain
26 FAM161AinteractorYajC (PF02699, IPR003849): Preprotein translocase subunit
UPF0564 (PF10595, IPR019579): Uncharacterised protein family UPF0564
27 FAM214BinteractorChromosome_seg (PF13889): Chromosome segregation during meiosis
DUF4210 (PF13915, IPR025261): Domain of unknown function (DUF4210)
28 FAM50BinteractorAtrophin-1 (PF03154, IPR002951): Atrophin-1 family
XAP5 (PF04921, IPR007005): XAP5, circadian clock regulator
29 FAM74A4interactorNA
30 FGF12oncoproteinFGF (PF00167, IPR002209, SM00442): Fibroblast growth factor
31 FRMD6interactorFERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
HTH_24 (PF13412, IPR011991): Winged helix-turn-helix DNA-binding
32 GATA1oncoproteinGATA (PF00320, IPR000679, SM00401): GATA zinc finger
Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain
33 GLRX3interactorGlutaredoxin (PF00462, IPR002109): Glutaredoxin
Thioredoxin (PF00085, IPR013766): Thioredoxin
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
34 GMCL1P1interactorNA
35 GTF2BinteractorCyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
36 HDAC1suppressorFSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
37 HDAC11interactorHist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
38 HDAC2suppressorHist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
39 HDAC3suppressorHist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
40 HDAC4oncoproteinBorrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
41 HDAC5interactorHist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
42 HDAC7interactorHist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO
43 IKZF1parental proteinDesulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
44 IKZF2suppressorADK_lid (PF05191, IPR007862): Adenylate kinase, active site lid
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
45 IKZF3suppressorC1_2 (PF03107, IPR004146): C1 domain
Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2H2_7 (PF15269): Zinc-finger
46 IKZF4interactorADK_lid (PF05191, IPR007862): Adenylate kinase, active site lid
PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
FancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nuclease
47 IKZF5interactorzf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
zf-C2H2_7 (PF15269): Zinc-finger
48 ISCUinteractorNifU_N (PF01592, IPR002871): NifU-like N terminal domain
49 KIF9interactorLaminin_II (PF06009, IPR010307): Laminin Domain II
Mvb12 (PF09452, IPR019014): ESCRT-I subunit Mvb12
Prismane (PF03063, IPR004137): Prismane/CO dehydrogenase family
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
50 LMO3oncoproteinLIM (PF00412, IPR001781, SM00132): LIM domain
51 LSM4interactorLSM (PF01423, IPR001163): LSM domain
52 MAD2L2interactorHORMA (PF02301, IPR003511): HORMA domain
53 MAP1SinteractorLactamase_B_6 (PF16661, IPR001279): Metallo-beta-lactamase superfamily domain
54 MCRS1interactorFHA (PF00498, IPR000253, SM00240): FHA domain
MCRS_N (PF13325, IPR025999): N-terminal region of micro-spherule protein
55 MORF4L1interactorMRG (PF05712, IPR026541): MRG
Fmp27_WPPW (PF10359, IPR019449): RNA pol II promoter Fmp27 protein domain
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
56 MORF4L2interactorMRG (PF05712, IPR026541): MRG
57 MPPED2interactorMetallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
58 MTA1oncoproteinBAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
59 NCOR2oncoproteinCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK)
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family
PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Spt20 (PF12090, IPR021950): Spt20 family
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518)
GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
60 NEK6interactorPkinase (PF00069, IPR000719): Protein kinase domain
61 NOC4LinteractorCBF (PF03914, IPR005612, SM00521): CBF/Mak21 family
62 NOTCH1suppressorAnk (PF00023, IPR002110, SM00248): Ankyrin repeat
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
NOD (PF06816, IPR010660): NOTCH protein
NODP (PF07684, IPR011656): NOTCH protein
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Notch (PF00066, IPR000800, SM00004): LNR domain
DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
63 NUDT21interactorNUDIX_2 (PF13869, IPR016706): Nucleotide hydrolase
64 PIN1suppressorRotamase (PF00639, IPR000297): PPIC-type PPIASE domain
WW (PF00397, IPR001202, SM00456): WW domain
65 PNKPinteractorPNK3P (PF08645, IPR013954): Polynucleotide kinase 3 phosphatase
AAA_33 (PF13671): AAA domain
66 PRKAB2interactorAMPKBI (PF04739, IPR006828, SM01010): 5'-AMP-activated protein kinase beta subunit, interaction domain
AMPK1_CBM (PF16561, IPR032640): Glycogen recognition site of AMP-activated protein kinase
67 PRSS23interactorTrypsin (PF00089, IPR001254, SM00020): Trypsin
68 PSMA1interactorProteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
69 PSMA4interactorProteasome (PF00227, IPR001353): Proteasome subunit
U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
70 PTTG1oncoproteinSecurin (PF04856, IPR006940): Securin sister-chromatid separation inhibitor
71 RAD51DoncoproteinRad51 (PF08423, IPR013632): Rad51
72 RBBP4oncoproteineIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
73 RBBP8suppressorZapB (PF06005, IPR009252): Cell division protein ZapB
Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus
CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
DUF4446 (PF14584, IPR027981): Protein of unknown function (DUF4446)
74 RWDD2BinteractorDUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115)
RWD (PF05773, IPR006575, SM00591): RWD domain
75 SCNM1interactorzf-SCNM1 (PF15803, IPR031622): Zinc-finger of sodium channel modifier 1
SCNM1_acidic (PF15805, IPR031625): Acidic C-terminal region of sodium channel modifier 1 SCNM1
76 SDCBPinteractorPDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
77 SH2D4AinteractorCytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
SH2 (PF00017, IPR000980, SM00252): SH2 domain
DUF2039 (PF10217, IPR019351): Uncharacterized conserved protein (DUF2039)
78 SH3BP2oncoproteinPH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
79 SIN3AoncoproteinSin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
80 SIN3BinteractorSin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
81 SMARCA4suppressorDUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
BRK (PF07533, IPR006576, SM00592): BRK domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065)
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
82 SMARCE1interactorDUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1)
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
83 SNRPFinteractorLSM (PF01423, IPR001163): LSM domain
84 SNW1interactorSKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
85 SPATC1LinteractorSperiolin_N (PF15058, IPR029385): Speriolin N terminus
Speriolin_C (PF15059, IPR029384): Speriolin C-terminus
86 SYT17interactorC2 (PF00168, IPR000008, SM00239): C2 domain
87 TBPinteractorTBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
88 TDGinteractorPox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily
89 UBE2IinteractorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
90 WTAPoncoproteinDUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
SOSSC (PF15925, IPR031821): SOSS complex subunit C
Wtap (PF17098, IPR029732): Pre-mRNA-splicing regulator WTAP
91 ZMAT2interactorCgr1 (PF03879, IPR005579): Cgr1 family
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
92 ZNF417interactorA2L_zn_ribbon (PF08792, IPR014900): A2L zinc ribbon domain
C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
93 ZNF581interactorzf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger

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