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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: AW390893 is the fusion of parental proteins GSTP1, WHSC1 (from a repository: Wed Dec 7 14:00:29 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)64
The number (and %) of the onco-proteins23 (35.94 %)
The number (and %) of the tumor suppressors9 (14.06 %)
Total number of binary PPIs (saturation %)329 (16.32 %)
The number (and %) of affected PPIs63 (19.15 %)
The number of possible different fusions13
PPI diameter2
PPI radius1
The average degree of PPI9.375
Assortativity coefficient-0.2785
The network average Clustering coefficient0.535
The number (and %) of a zero Clustering coefficients4 (6.25 %)
The number (and %) of a zero Betweenness Centrality14 (21.88 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: WHSC1,GSTP1 All fusions
: AW390893;
Proteins found in more fusions RBMX (see 3 fusions); UBE2O (see 1 fusions); APP (see 4 fusions); KIF11 (see 1 fusions); MAPK1 (see 1 fusions); MCM2 (see 1 fusions); TRIM28 (see 1 fusions); KDM1A (see 2 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); PCNA (see 1 fusions); MAP3K1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AW390893chimera630.1212393.064SET (PF00856, IPR001214, SM00317): SET domain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
2 ACTA2interactor50.7000.908Actin (PF00022, IPR004000, SM00268): Actin
3 APPprotein found in more fusions160.29556.853APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
4 APPBP2interactor30.6670.500TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
5 ARoncoprotein80.4765.952Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
6 ATF2oncoprotein80.5714.205bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
7 BRD4oncoprotein30.6670.400Caldesmon (PF02029, IPR006018): Caldesmon
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Stm1_N (PF09598, IPR019084): Stm1
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain
BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation
BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
8 CCDC88Cinteractor31.0000DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
Fez1 (PF06818): Fez1
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
HOOK (PF05622, IPR008636): HOOK protein
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
9 CDK2suppressor130.5618.660Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
10 CTNNB1oncoprotein170.41946.166Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
11 CUL2suppressor110.47318.277Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
12 CUL3protein found in more fusions230.290107.840Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
13 CUL7protein found in more fusions180.27249.075ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
14 DDX20interactor70.6001.719DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
15 DTLinteractor21.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
16 ESR1suppressor180.33845.726Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
17 FBXL12interactor100F-box-like (PF12937, IPR001810): F-box-like
18 FOXD4interactor100Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
19 FUSsuppressor160.55016.863Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
20 GEMIN5interactor80.5365.889WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
21 GOLGA3interactor40.6670.500ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
G-gamma (PF00631, IPR015898, SM00224): GGL domain
SOGA (PF11365, IPR027881): Protein SOGA
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
22 HDAC1suppressor140.44926.121FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
23 HDAC2suppressor130.51514.334Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
24 HIST1H3Ainteractor110.40017.940Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
25 HIST2H3Cinteractor80.3939.967Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
26 HIST3H3interactor100.55610.558Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
27 HNRNPA1interactor200.39861.458RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
28 IQGAP1interactor130.51315.382CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
IDEAL (PF08858, IPR014957, SM00914): IDEAL domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
WW (PF00397, IPR001202, SM00456): WW domain
29 ISG15suppressor50.6001.952ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
30 ITGA4interactor140.48716.002FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
31 KDM1Aprotein found in more fusions120.50912.784Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
32 KIF11protein found in more fusions40.6670.333Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
Gag_p17 (PF00540, IPR000071): gag gene protein p17 (matrix protein)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510)
Microtub_bind (PF13931, IPR025901): Kinesin-associated microtubule-binding
33 KRT31interactor21.0000Filament (PF00038, IPR001664): Intermediate filament protein
34 KRTAP10-7interactor40.6671.000Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
PMG (PF05287, IPR007951): PMG protein
DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106)
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
35 LIG4interactor21.0000APG17 (PF04108, IPR007240): Autophagy protein Apg17
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region
DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain
DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus
DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
36 LSM1interactor100LSM (PF01423, IPR001163): LSM domain
37 MAP3K1oncoprotein70.6004.167zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Pkinase (PF00069, IPR000719): Protein kinase domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
38 MAPK1oncoprotein100.38911.782Pkinase (PF00069, IPR000719): Protein kinase domain
39 MAPK8oncoprotein100.41716.500DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
40 MCM2oncoprotein190.38652.431AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
41 MYBBP1Asuppressor110.45515.788DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal
42 MYCBP2interactor21.0000ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
PHR (PF08005, IPR012983): PHR domain
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
SH3_3 (PF08239, IPR003646): Bacterial SH3 domain
XPA_N (PF01286, IPR022652): XPA protein N-terminal
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
43 NOTCH2NLinteractor21.0000EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
44 NTRK1oncoprotein270.237163.963I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
45 PCNAoncoprotein130.37925.287PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
46 PLEConcoprotein110.43611.052CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
S10_plectin (PF03501, IPR005326): Plectin/S10 domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
DUF2229 (PF09989, IPR018709): CoA enzyme activase uncharacterised domain (DUF2229)
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
YlqD (PF11068, IPR021297): YlqD protein
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
47 PNO1interactor21.0000KH_1 (PF00013, IPR004088, SM00322): KH domain
48 PRR11interactor21.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
PRIMA1 (PF16101): Proline-rich membrane anchor 1
49 RBM10interactor40.6670.182G-patch (PF01585, IPR000467, SM00443): G-patch domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
GSIII_N (PF12437, IPR022147): Glutamine synthetase type III N terminal
G-patch_2 (PF12656, IPR026822): DExH-box splicing factor binding site
zf-C2H2_4 (PF13894): C2H2-type zinc finger
DUF4337 (PF14235, IPR025570): Domain of unknown function (DUF4337)
FAM176 (PF14851): FAM176 family
50 RBM4Binteractor31.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCHC (PF00098, IPR001878): Zinc knuckle
51 RBMXsuppressor130.6066.779RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
52 RPL14interactor140.40729.151KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
53 SCAF1oncoprotein21.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
Med8 (PF10232, IPR019364): Mediator of RNA polymerase II transcription complex subunit 8
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FAM220 (PF15487, IPR029155): FAM220 family
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
DUF4778 (PF16008, IPR031958): Domain of unknown function (DUF4778)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
54 SIN3Aoncoprotein120.53016.567Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
55 SIN3Binteractor80.7502.889Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
56 SIRT7interactor170.25064.607DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
57 SKIV2L2interactor40.6670.389DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DSHCT (PF08148, IPR012961, SM01142): DSHCT (NUC185) domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
rRNA_proc-arch (PF13234, IPR025696): rRNA-processing arch domain
58 SMN1interactor130.36423.186SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
59 THRAP3oncoprotein50.4001.332API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
60 TIAM1oncoprotein100PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
PH (PF00169, IPR001849, SM00233): PH domain
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
AAA_22 (PF13401, IPR003593): AAA domain
61 TRAF2interactor60.5004.000MATH (PF00917, IPR002083, SM00061): MATH domain
Sina (PF03145, IPR018121): Seven in absentia protein family
SlyX (PF04102, IPR007236): SlyX
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
62 TRIM28protein found in more fusions140.35922.652ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
63 UBE2Oprotein found in more fusions50.5001.667BUD22 (PF09073, IPR015158): BUD22
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
64 VCAM1interactor110.5647.202C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ACY1suppressorPeptidase_M20 (PF01546, IPR002933): Peptidase family M20/M25/M40
2 COPS5interactorJAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
3 FANCConcoproteinFanconi_C (PF02106, IPR000686): Fanconi anaemia group C protein
4 FN1oncoproteinfn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
5 GABPB1oncoproteinAnk_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
AAA_23 (PF13476): AAA domain
Ank_4 (PF13637): Ankyrin repeats (many copies)
DUF4265 (PF14085, IPR025361): Domain of unknown function (DUF4265)
6 GEMIN4interactorNA
7 GSTP1parental proteinGST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
8 GSTT2interactorGST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
9 GSTT2BinteractorGST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
10 HIST1H4AinteractorCENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
11 IFI16suppressorHIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
12 KRTAP10-3interactorKeratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
13 KRTAP10-9interactorKeratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
14 MAP1BinteractorDUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
MAP1B_neuraxin (PF00414, IPR000102): Neuraxin and MAP1B repeat
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
Striatin (PF08232, IPR013258): Striatin family
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
15 MDC1suppressorFHA (PF00498, IPR000253, SM00240): FHA domain
DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274)
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
16 MLH1suppressorDNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Mlh1_C (PF16413, IPR032189): DNA mismatch repair protein Mlh1 C-terminus
17 PRPSAP2interactorPribosyltran_N (PF13793, IPR029099): N-terminal domain of ribose phosphate pyrophosphokinase
Pribosyl_synth (PF14572, IPR005946): Phosphoribosyl synthetase-associated domain
18 PTNoncoproteinPTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain
PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
19 PTPN13suppressorFERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
KIND (PF16474, IPR011019, SM00750): Kinase non-catalytic C-lobe domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
PTN13_u3 (PF16599): Unstructured linker region on PTN13 protein between PDZ
20 RPL6interactorRibosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
21 RPL8interactorRibosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain
Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain
22 RPLP0interactorRibosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
23 TGM2interactorTransglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain
Transglut_N (PF00868, IPR001102): Transglutaminase family
Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
24 TXNL4AinteractorDIM1 (PF02966, IPR004123): Mitosis protein DIM1
25 WDR77oncoproteinLT-IIB (PF06453, IPR010503): Type II heat-labile enterotoxin , B subunit (LT-IIB)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
26 WHSC1parental proteinPHD (PF00628, IPR019787, SM00249): PHD-finger
PWWP (PF00855, IPR000313, SM00293): PWWP domain
REV (PF00424, IPR000625): REV protein (anti-repression trans-activator protein)
SET (PF00856, IPR001214, SM00317): SET domain
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
27 ZC3H3interactorzf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
CCDC24 (PF15669, IPR031367): Coiled-coil domain-containing protein 24 family
28 ZNF518AinteractorCBP4 (PF07960, IPR012420): CBP4
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Fer4_9 (PF13187, IPR017896): 4Fe-4S dicluster domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain

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