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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: AW380044 is the fusion of parental proteins CHD3, NARS (from a repository: Wed Dec 7 20:40:23 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)198
The number (and %) of the onco-proteins63 (31.82 %)
The number (and %) of the tumor suppressors29 (14.65 %)
Total number of binary PPIs (saturation %)1498 (7.68 %)
The number (and %) of affected PPIs197 (13.15 %)
The number of possible different fusions37
PPI diameter2
PPI radius1
The average degree of PPI14.222
Assortativity coefficient-0.2591
The network average Clustering coefficient0.499
The number (and %) of a zero Clustering coefficients9 (4.55 %)
The number (and %) of a zero Betweenness Centrality30 (15.15 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions
PPI for parental proteins: NARS1,CHD3 All fusions
: AW380044;
Proteins found in more fusions CTBP1 (see 2 fusions); GSK3B (see 1 fusions); HSF1 (see 3 fusions); BCL6 (see 2 fusions); IVNS1ABP (see 2 fusions); UBA3 (see 1 fusions); IKZF1 (see 1 fusions); AIMP2 (see 1 fusions); IMMT (see 4 fusions); CTTN (see 1 fusions); HTT (see 1 fusions); TSC22D1 (see 5 fusions); UBC (see 1 fusions); DDX5 (see 1 fusions); PRPF40A (see 2 fusions); TP53 (see 3 fusions); SNW1 (see 1 fusions); SAT1 (see 5 fusions); LUC7L2 (see 2 fusions); PUF60 (see 2 fusions); TRIM28 (see 1 fusions); KPNB1 (see 2 fusions); PLOD2 (see 1 fusions); ATXN1 (see 3 fusions); CREB1 (see 2 fusions); SERBP1 (see 1 fusions); HNRNPL (see 2 fusions); SF1 (see 1 fusions); KMT2A (see 16 fusions); MCM2 (see 1 fusions); KDM1A (see 2 fusions); CSNK2A1 (see 1 fusions); MBD2 (see 1 fusions); UROD (see 1 fusions); TNNT1 (see 1 fusions); CHD4 (see 6 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient		 Betweenness
Centrality		 Domains (Pfam, InterPro, SMART): description
1 AW380044chimera1970.06325673.766CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N)
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
2 AARSinteractor110.41813.240DHHA1 (PF02272, IPR003156): DHHA1 domain
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
tRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
3 ABL1oncoprotein130.34824.344Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
4 ADH5interactor51.0000ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain
ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
5 AIMP2suppressor150.44023.523GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
AIMP2_LysRS_bd (PF16780, IPR031889): AIMP2 lysyl-tRNA synthetase binding domain
6 ATPIF1interactor21.0000DivIC (PF04977, IPR007060): Septum formation initiator
IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
7 ATXN1protein found in more fusions110.28919.800AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
8 BARD1suppressor220.24887.716BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
9 BCL6oncoprotein120.54513.201BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
DZR (PF12773, IPR025874): Double zinc ribbon
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
10 BHLHE40interactor90.6433.027Hairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
11 BMI1oncoprotein220.26783.077zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
12 C1QBPinteractor140.42925.538MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein
DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
13 C4orf17interactor21.0000SPATIAL (PF15256): SPATIAL
14 CASP6interactor40.6671.000Peptidase_C14 (PF00656, IPR011600): Caspase domain
15 CASP8suppressor80.3819.167DED (PF01335, IPR001875, SM00031): Death effector domain
Peptidase_C14 (PF00656, IPR011600): Caspase domain
16 CCDC8interactor280.219129.995Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
17 CD2BP2interactor70.6192.712GYF (PF02213, IPR003169, SM00444): GYF domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region
18 CDK2AP1suppressor150.9900.111CDK2AP (PF09806, IPR019187): Cyclin-dependent kinase 2-associated protein
19 CEP128interactor100.28925.280DUF1129 (PF06570, IPR009214): Protein of unknown function (DUF1129)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
SpoOE-like (PF09388, IPR018540): Spo0E like sporulation regulatory protein
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
TraF_2 (PF13729, IPR032811): F plasmid transfer operon, TraF, protein
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
HAUS6_N (PF14661, IPR028163): HAUS augmin-like complex subunit 6 N-terminus
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
20 CEP170interactor80.32111.168FHA (PF00498, IPR000253, SM00240): FHA domain
DUF4254 (PF14063, IPR025350): Protein of unknown function (DUF4254)
CEP170_C (PF15308, IPR029300): CEP170 C-terminus
21 CHD4oncoprotein400.352211.703CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
FAM176 (PF14851): FAM176 family
Coilin_N (PF15862, IPR031722): Coilin N-terminus
22 CHD6interactor21.0000CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
BORG_CEP (PF14957, IPR029273): Cdc42 effector
23 CIRBPoncoprotein120.33318.612RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
24 CPEinteractor21.0000Peptidase_M14 (PF00246, IPR000834, SM00631): Zinc carboxypeptidase
CarboxypepD_reg (PF13620): Carboxypeptidase regulatory-like domain
25 CPSF1interactor90.4728.589CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
HPS3_N (PF14761, IPR029437): Hermansky-Pudlak syndrome 3
26 CRCT1interactor40.6670.619NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
27 CREB1oncoprotein170.43329.142bZIP_1 (PF00170, IPR004827): bZIP transcription factor
pKID (PF02173, IPR003102): pKID domain
DUF4988 (PF16378, IPR032149): Domain of unknown function
28 CSNK2A1oncoprotein340.280183.087Pkinase (PF00069, IPR000719): Protein kinase domain
29 CSTF2interactor80.35711.467RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal
CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
30 CTBP1protein found in more fusions170.39227.1452-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
31 CTTNoncoprotein80.5715.750FadA (PF09403, IPR018543): Adhesion protein FadA
HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
32 CUL2suppressor210.31466.374Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
33 DDX19Binteractor70.33311.900DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
34 DDX5oncoprotein230.29472.720DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
35 DUSP19interactor100DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
36 EIF4Binteractor130.57615.321RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3774 (PF12609, IPR022251): Wound-induced protein
PROL5-SMR (PF15621, IPR026288): Proline-rich submaxillary gland androgen-regulated family
37 ENO1oncoprotein190.26972.788Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
38 EPRSinteractor150.46724.537GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain
ProRS-C_1 (PF09180, IPR016061, SM00946): Prolyl-tRNA synthetase, C-terminal
tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain
tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
39 FABP4interactor21.0000Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
40 FAM134Ainteractor100INSIG (PF07281, IPR025929): Insulin-induced protein (INSIG)
Reticulon (PF02453, IPR003388): Reticulon
41 FAM213Binteractor100AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
AhpC-TSA_2 (PF13911, IPR032801): AhpC/TSA antioxidant enzyme
42 FBP2interactor200FBPase (PF00316, IPR000146): Fructose-1-6-bisphosphatase, N-terminal domain
43 FN1oncoprotein330.222184.779fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
44 FUBP1oncoprotein100.5338.190DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897)
KH_1 (PF00013, IPR004088, SM00322): KH domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
45 GADD45Asuppressor60.7000.889Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
46 GANABsuppressor110.6008.212Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31
Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like
DUF5110 (PF17137): Domain of unknown function (DUF5110)
47 GARSinteractor160.28358.357HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
48 GATAD2Ainteractor180.8763.440DUF2299 (PF10061, IPR018747): Uncharacterized conserved protein (DUF2299)
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
P66_CC (PF16563, IPR032346): Coiled-coil and interaction region of P66A and P66B with MBD2
49 GATAD2Binteractor220.70114.110DUF1178 (PF06676, IPR009562): Protein of unknown function (DUF1178)
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
DUF3619 (PF12279, IPR022064): Protein of unknown function (DUF3619)
P66_CC (PF16563, IPR032346): Coiled-coil and interaction region of P66A and P66B with MBD2
50 GIT1interactor110.24424.352ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
GIT_SHD (PF08518, IPR013724, SM00555): Spa2 homology domain (SHD) of GIT
GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
FlxA (PF14282, IPR025577): FlxA-like protein
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
51 GPS2oncoprotein60.6671.290G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
52 GRB10oncoprotein21.0000BPS (PF08947, IPR015042): BPS (Between PH and SH2)
PH (PF00169, IPR001849, SM00233): PH domain
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
Argos (PF11581, IPR021633): Antagonist of EGFR signalling, Argos
53 GSK3Bsuppressor100.44413.258Pkinase (PF00069, IPR000719): Protein kinase domain
54 HABP4interactor50.6001.643HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
55 HDAC1suppressor550.273501.747FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
56 HDAC2suppressor510.319324.894Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
57 HDAC3suppressor160.27632.268Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
58 HIC1suppressor90.5363.671BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
59 HIST1H2BBinteractor50.6001.750Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
60 HIST1H3Ainteractor250.35589.459Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
61 HNRNPLprotein found in more fusions130.51511.748RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
62 HSD17B10interactor60.6671.545adh_short (PF00106, IPR002198): short chain dehydrogenase
63 HSF1protein found in more fusions110.44410.739DUF247 (PF03140, IPR004158): Plant protein of unknown function
Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
64 HSPB2interactor60.5002.400Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
65 HSPH1oncoprotein90.7782.141HSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
66 HTTprotein found in more fusions100.4449.268HEAT (PF02985, IPR000357): HEAT repeat
SPX (PF03105, IPR004331): SPX domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF3652 (PF12372, IPR024613): Huntingtin protein region
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
67 IARSinteractor170.41245.410Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
68 IKinteractor100.6392.985Lsm_interact (PF05391, IPR008669): Lsm interaction motif
RED_C (PF07807, IPR012492): RED-like protein C-terminal region
RED_N (PF07808, IPR012916): RED-like protein N-terminal region
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
69 IKZF1suppressor120.6554.353Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
70 IMMTprotein found in more fusions150.22043.859Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
71 IVNS1ABPprotein found in more fusions80.3816.575BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
72 JUNoncoprotein190.32051.715bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
73 JUPsuppressor130.57713.756Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
74 KARSinteractor130.52619.167tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N)
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
75 KDM1Aprotein found in more fusions350.340214.543Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
76 KDM5Binteractor110.8731.602ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
JmjN (PF02375, IPR003349, SM00545): jmjN domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
PLU-1 (PF08429, IPR013637): PLU-1-like protein
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Rubredoxin (PF00301, IPR024935): Rubredoxin
zf-C5HC2 (PF02928, IPR004198): C5HC2 zinc finger
Lipoprotein_20 (PF13942, IPR025262): YfhG lipoprotein
77 KIAA1217interactor21.0000AIP3 (PF03915, IPR022782, SM00806): Actin interacting protein 3
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
MRI (PF15325, IPR028278): Modulator of retrovirus infection
78 KIF15interactor31.0000Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
SlyX (PF04102, IPR007236): SlyX
STE (PF02200, IPR003120, SM00424): STE like transcription factor
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
FlxA (PF14282, IPR025577): FlxA-like protein
HMMR_C (PF15908, IPR031794): Hyaluronan mediated motility receptor C-terminal
79 KLHL20interactor60.5003.333BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
80 KMT2Aoncoprotein200.52030.442AT_hook (PF02178, IPR017956, SM00384): AT hook motif
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SET (PF00856, IPR001214, SM00317): SET domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
81 KPNB1protein found in more fusions210.32661.376Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
CLASP_N (PF12348, IPR024395): CLASP N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
HEAT_EZ (PF13513): HEAT-like repeat
82 LARSinteractor120.60610.387Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
83 LGR4interactor110.28916.5957tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
84 LILRA3interactor100DUF11 (PF01345, IPR001434): Domain of unknown function DUF11
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PPAK (PF02818, IPR004168): PPAK motif
Titin_Z (PF09042, IPR015129): Titin Z
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ig_3 (PF13927): Immunoglobulin domain
85 LRIF1interactor160.21066.555LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1
86 LRRC42interactor50.4001.459LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
87 LSM1interactor21.0000LSM (PF01423, IPR001163): LSM domain
88 LUC7L2protein found in more fusions200.24685.367LUC7 (PF03194, IPR004882): LUC7 N_terminus
Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein
Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
89 MAFGoncoprotein31.0000bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
ThrE_2 (PF12821, IPR024528): Threonine/Serine exporter, ThrE
90 MAN2A2interactor40.5000.983Alpha-mann_mid (PF09261, IPR015341, SM00872): Alpha mannosidase middle domain
Glyco_hydro_38 (PF01074, IPR000602): Glycosyl hydrolases family 38 N-terminal domain
Glyco_hydro_38C (PF07748, IPR011682): Glycosyl hydrolases family 38 C-terminal domain
91 MBD2oncoprotein200.8255.425API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain
MBD_C (PF14048, IPR025884): C-terminal domain of methyl-CpG binding protein 2 and 3
MBDa (PF16564, IPR032343): p55-binding region of Methyl-CpG-binding domain proteins MBD
92 MBD3interactor300.51067.538DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain
93 MBD3L1interactor160.9500.938MBD_C (PF14048, IPR025884): C-terminal domain of methyl-CpG binding protein 2 and 3
MBDa (PF16564, IPR032343): p55-binding region of Methyl-CpG-binding domain proteins MBD
94 MCM2oncoprotein330.244191.801AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
95 METAP2oncoprotein30.6671.000Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
SRP72 (PF08492, IPR013699): SRP72 RNA-binding domain
TSGP1 (PF07771, IPR011694): Tick salivary peptide group 1
96 MOV10interactor240.246108.860AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
97 MTA1oncoprotein310.48293.068BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
98 MTA2interactor330.47099.608BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
Resolvase (PF00239, IPR006119, SM00857): Resolvase, N terminal domain
DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
99 MTA3oncoprotein220.68024.578BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
100 MX1interactor41.0000Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
101 MYBoncoprotein80.5364.886Cmyb_C (PF09316, IPR015395): C-myb, C-terminal
LMSTEN (PF07988, IPR012642): LMSTEN motif
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
102 NAB2oncoprotein31.0000NCD1 (PF04904, IPR006988): NAB conserved region 1 (NCD1)
NCD2 (PF04905, IPR006989): NAB conserved region 2 (NCD2)
103 NEFLinteractor60.4672.076Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
NOA36 (PF06524, IPR010531): NOA36 protein
BORG_CEP (PF14957, IPR029273): Cdc42 effector
104 NPHP1interactor70.4675.567SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FAM176 (PF14851): FAM176 family
Speriolin_N (PF15058, IPR029385): Speriolin N terminus
DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746)
105 NR1H2oncoprotein50.6000.829zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
106 NR4A1suppressor60.6002.305zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
107 NTRK1oncoprotein780.1211770.070I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
108 NUP50interactor60.5334.333NUP50 (PF08911, IPR015007): NUP50 (Nucleoporin 50 kDa)
Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
109 NXF1interactor290.198167.104NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
110 OSBPinteractor120.57611.238Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein
PH (PF00169, IPR001849, SM00233): PH domain
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
HlyD_D23 (PF16576, IPR032317): Barrel-sandwich domain of CusB or HlyD membrane-fusion
111 OTUD6Binteractor21.0000Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
HemY_N (PF07219, IPR010817): HemY protein N-terminus
OTU (PF02338, IPR003323): OTU-like cysteine protease
DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335)
112 PAICSinteractor60.7000.274AIRC (PF00731, IPR000031, SM01001): AIR carboxylase
SAICAR_synt (PF01259, IPR028923): SAICAR synthetase
113 PAPOLAinteractor100.28916.691PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain
PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain
Macoilin (PF09726, IPR019130): Transmembrane protein
114 PCMT1interactor100.53310.177PCMT (PF01135, IPR000682): Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
115 PCNTinteractor80.6436.914Caldesmon (PF02029, IPR006018): Caldesmon
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF1640 (PF07798, IPR024461): Protein of unknown function (DUF1640)
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
SlyX (PF04102, IPR007236): SlyX
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
PACT_coil_coil (PF10495, IPR019528): Pericentrin-AKAP-450 domain of centrosomal targeting protein
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
Colicin-DNase (PF12639, IPR024622): DNase/tRNase domain of colicin-like bacteriocin
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
DUF4239 (PF14023, IPR025333): Protein of unknown function (DUF4239)
WD40_alt (PF14077, IPR026987): Alternative WD40 repeat motif
FlxA (PF14282, IPR025577): FlxA-like protein
FAM184 (PF15665): Family with sequence similarity 184, A and B
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
116 PHF20L1interactor130.8333.688MBT (PF02820, IPR004092, SM00561): mbt repeat
PHD (PF00628, IPR019787, SM00249): PHD-finger
U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34
DUF3776 (PF12618, IPR022255): Protein of unknown function (DUF3776)
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537)
PEHE (PF15275, IPR029332): PEHE domain
EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
PHD20L1_u1 (PF16660): PHD finger protein 20-like protein 1
117 PHF6suppressor90.5286.535zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
YqfQ (PF14181, IPR025571): YqfQ-like protein
118 PIAS4interactor220.29991.614CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SAP (PF02037, IPR003034, SM00513): SAP domain
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
119 PLK4interactor50.6672.000ABC1 (PF03109, IPR004147): ABC1 family
Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
DUF4520 (PF15016, IPR027865): Domain of unknown function (DUF4520)
120 PLOD2protein found in more fusions120.5648.2972OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily
Anp1 (PF03452, IPR005109): Anp1
Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
121 PRG2interactor100Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
DUF4628 (PF15429, IPR027851): Domain of unknown function (DUF4628)
122 PRMT3interactor110.6557.101PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA)
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
123 PRPF40Aprotein found in more fusions160.43821.373FF (PF01846, IPR002713, SM00441): FF domain
MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain
Transformer (PF06495, IPR010519): Fruit fly transformer protein
WW (PF00397, IPR001202, SM00456): WW domain
YqzE (PF14038, IPR025622): YqzE-like protein
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus
SOBP (PF15279, IPR026092): Sine oculis-binding protein
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
124 PRPS1oncoprotein31.0000Pribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain
Pribosyltran_N (PF13793, IPR029099): N-terminal domain of ribose phosphate pyrophosphokinase
Pribosyl_synth (PF14572, IPR005946): Phosphoribosyl synthetase-associated domain
125 PSMD14interactor50.5003.067JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
126 PSME1interactor90.32113.258PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit
PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit
RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component)
127 PTNoncoprotein150.20953.033PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain
PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
128 PTPRSinteractor30.6670.500fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
Ig_3 (PF13927): Immunoglobulin domain
129 PUF60protein found in more fusions160.37125.474RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Titin_Z (PF09042, IPR015129): Titin Z
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
130 PUS1interactor100PseudoU_synth_1 (PF01416, IPR020097): tRNA pseudouridine synthase
131 RABIFinteractor100Mss4 (PF04421, IPR007515): Mss4 protein
DNA_RNApol_7kD (PF03604, IPR006591, SM00659): DNA directed RNA polymerase, 7 kDa subunit
132 RAD21oncoprotein170.36844.151Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein
Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
133 RAD51interactor90.5004.624Rad51 (PF08423, IPR013632): Rad51
HHH_5 (PF14520): Helix-hairpin-helix domain
134 RARSinteractor120.6218.202Arg_tRNA_synt_N (PF03485, IPR005148, SM01016): Arginyl tRNA synthetase N terminal domain
DALR_1 (PF05746, IPR008909, SM00836): DALR anticodon binding domain
DivIC (PF04977, IPR007060): Septum formation initiator
tRNA-synt_1d (PF00750, IPR015945): tRNA synthetases class I (R)
Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region
135 RBBP4oncoprotein390.409151.829eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
136 RBBP7suppressor350.455100.341WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
137 RGS2oncoprotein40.5001.210RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
138 RNF2interactor350.282166.785zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
139 RPL10suppressor160.42526.111Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
140 RPL24interactor120.43913.141MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
141 RPL29interactor60.6001.732BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
Ribosomal_L29e (PF01779, IPR002673): Ribosomal L29e protein family
142 SAFBsuppressor60.5332.621RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAP (PF02037, IPR003034, SM00513): SAP domain
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
143 SAMHD1interactor210.43748.942HD (PF01966, IPR006674): HD domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
144 SAT1protein found in more fusions80.4295.127Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
145 SATB1oncoprotein140.44024.788CUT (PF02376, IPR003350, SM01109): CUT domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371)
ULD (PF16534, IPR032392): Ubiquitin-like oligomerisation domain of SATB
CUTL (PF16557, IPR032355): CUT1-like DNA-binding domain of SATB
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
146 SCLT1oncoprotein60.4677.167DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
SlyX (PF04102, IPR007236): SlyX
XhlA (PF10779, IPR019715): Haemolysin XhlA
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Imm7 (PF15585, IPR028965): Immunity protein 7
CCCAP (PF15964, IPR031887): Centrosomal colon cancer autoantigen protein family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
147 SDCCAG3interactor50.5004.000GA (PF01468, IPR002988, SM00844): GA module
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
148 SEC23Ainteractor140.48419.194Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
149 SERBP1protein found in more fusions110.5337.896HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
150 SERF2interactor1004F5 (PF04419, IPR007513): 4F5 protein family
151 SERPINB5suppressor40.5002.400Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
152 SF1protein found in more fusions190.34653.505UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181)
zf-CCHC (PF00098, IPR001878): Zinc knuckle
KH_1 (PF00013, IPR004088, SM00322): KH domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain
153 SGSM2interactor21.0000Cullin_binding (PF03556, IPR005176): Cullin binding
RUN (PF02759, IPR004012, SM00593): RUN domain
RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
DUF3548 (PF12068, IPR021935): Domain of unknown function (DUF3548)
154 SHMT2interactor110.30924.788SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
155 SIN3Aoncoprotein340.364154.314Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
156 SIRT1suppressor190.33349.364DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592)
SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
157 SIRT6suppressor130.5138.973SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
158 SIRT7interactor370.222263.074DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
159 SKILsuppressor80.5712.018c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain
DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family
DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115)
160 SLC27A6interactor21.0000AMP-binding (PF00501, IPR000873): AMP-binding enzyme
AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain
161 SMARCA2suppressor160.60016.457DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
BRK (PF07533, IPR006576, SM00592): BRK domain
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
162 SMARCA5interactor230.44242.569HAND (PF09110, IPR015194): HAND
SLIDE (PF09111, IPR015195): SLIDE
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DBINO (PF13892, IPR020838): DNA-binding domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
163 SMARCC2interactor220.34672.001GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
164 SNRNP40interactor50.7000.684WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
165 SNW1protein found in more fusions330.270194.892SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
166 SOX2oncoprotein290.360135.586HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
167 SRRTinteractor100.44411.723ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
Macoilin (PF09726, IPR019130): Transmembrane protein
DUF3546 (PF12066, IPR021933): Domain of unknown function (DUF3546)
DUF4187 (PF13821, IPR025239): Domain of unknown function (DUF4187)
168 SUMO1interactor160.38134.209Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
169 SUMO2interactor220.40546.031Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
170 SUV39H2interactor21.0000Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Pre-SET (PF05033, IPR007728): Pre-SET motif
SET (PF00856, IPR001214, SM00317): SET domain
Tox-GHH (PF15636, IPR028916): GHH signature containing HNH/Endo VII superfamily nuclease toxin
171 TAF6interactor120.8182.034CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
Spo0A_C (PF08769, IPR014879): Sporulation initiation factor Spo0A C terminal
TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF)
172 TAL1oncoprotein110.6005.677HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
173 TCERG1interactor90.5285.597FF (PF01846, IPR002713, SM00441): FF domain
WW (PF00397, IPR001202, SM00456): WW domain
Folliculin (PF11704, IPR021713): Vesicle coat protein involved in Golgi to plasma membrane transport
DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807)
DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886)
Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO
FAM150 (PF15129, IPR029364): FAM150 family
174 THOC7interactor60.3332.867EcoEI_R_C (PF08463, IPR013670): EcoEI R protein C-terminal
THOC7 (PF05615, IPR008501): Tho complex subunit 7
UPF0193 (PF05250, IPR007914): Uncharacterised protein family (UPF0193)
175 TNFRSF14oncoprotein30.6670.286Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Hum_adeno_E3A (PF05393, IPR008652): Human adenovirus early E3A glycoprotein
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
176 TNNT1protein found in more fusions60.6001.433Troponin (PF00992, IPR001978): Troponin
DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050)
177 TP53suppressor580.177811.208DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
178 TP73suppressor120.54510.218P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
179 TRIM28protein found in more fusions240.33267.336ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
180 TRMT1interactor100.51110.119TRM (PF02005, IPR002905): N2,N2-dimethylguanosine tRNA methyltransferase
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
181 TSC22D1suppressor80.3817.360SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
182 TSPAN6interactor21.0000Tetraspannin (PF00335, IPR018499): Tetraspanin family
183 TTRinteractor31.0000Transthyretin (PF00576, IPR023416, SM00095): HIUase/Transthyretin family
184 TWIST1oncoprotein90.6673.043ACC_epsilon (PF13822, IPR032716): Acyl-CoA carboxylase epsilon subunit
PRR20 (PF15708, IPR031439): Proline-rich protein family 20
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
185 TXNDC9interactor50.4003.633Thioredoxin (PF00085, IPR013766): Thioredoxin
DUF3619 (PF12279, IPR022064): Protein of unknown function (DUF3619)
186 UBA3protein found in more fusions31.0000E2_bind (PF08825, IPR014929): E2 binding domain
ThiF (PF00899, IPR000594): ThiF family
187 UBCprotein found in more fusions330.246217.624ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
188 UBE2Iinteractor390.198338.857UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
189 UBE2Sinteractor40.6670.286ALF (PF03752, IPR005506): Short repeats of unknown function
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
190 URODprotein found in more fusions50.5000.803URO-D (PF01208, IPR000257): Uroporphyrinogen decarboxylase (URO-D)
191 VIMsuppressor470.109753.180Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
192 XPO7interactor190.35162.448IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
193 XRCC4interactor70.5331.397XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4
194 XRCC5suppressor300.264148.721Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
195 XRCC6oncoprotein330.238202.531Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain
196 YAE1D1interactor30.6670.400Yae1_N (PF09811, IPR019191): Essential protein Yae1, N terminal
197 ZHX1interactor190.34650.512Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
Homez (PF11569, IPR024578): Homeodomain leucine-zipper encoding, Homez
zf-C2H2_4 (PF13894): C2H2-type zinc finger
TerB_C (PF15615, IPR028932): TerB-C domain
198 ZNF219interactor160.8923.729Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 CHD3parental proteinCHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
FAM176 (PF14851): FAM176 family
2 NARSparental proteintRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N)
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain

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