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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: AW369496 is the fusion of parental proteins PLSCR1, ITGB4 (from a repository: Wed Feb 7 09:04:02 2018)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)78
The number (and %) of the onco-proteins28 (35.90 %)
The number (and %) of the tumor suppressors8 (10.26 %)
Total number of binary PPIs (saturation %)224 (7.46 %)
The number (and %) of affected PPIs77 (34.38 %)
The number of possible different fusions16
PPI diameter2
PPI radius1
The average degree of PPI5.000
Assortativity coefficient-0.3551
The network average Clustering coefficient0.614
The number (and %) of a zero Clustering coefficients10 (12.82 %)
The number (and %) of a zero Betweenness Centrality36 (46.15 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: PLSCR1,ITGB4 All fusions
: AW369496;
Proteins found in more fusions HNRNPD (see 1 fusions); SHC1 (see 1 fusions); ILK (see 1 fusions); EWSR1 (see 2 fusions); APP (see 4 fusions); FRS3 (see 1 fusions); ATXN1 (see 3 fusions); ZBTB16 (see 3 fusions); VCP (see 4 fusions); ERBIN (see 4 fusions); EGFR (see 2 fusions); FBLN1 (see 3 fusions); SKI (see 1 fusions); SMAD3 (see 3 fusions); SREBF2 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AW369496chimera780.0405151.667Calx-beta (PF03160, IPR003644, SM00237): Calx-beta domain
EGF_2 (PF07974, IPR013111): EGF-like domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
SEA (PF01390, IPR000082, SM00200): SEA domain
STOP (PF05217, IPR024963): STOP protein
Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain
PSI_integrin (PF17205): Integrin plexin domain
2 ADAMTSL4interactor160.24280.833ADAM_spacer1 (PF05986, IPR010294): ADAM-TS Spacer 1
PLAC (PF08686, IPR010909, SM00022): PLAC (protease and lacunin) domain
TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain
Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type
3 ALOX12oncoprotein200Lipoxygenase (PF00305, IPR013819): Lipoxygenase
PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain
4 ANXA11interactor21.0000Annexin (PF00191, IPR018502, SM00335): Annexin
5 APPprotein found in more fusions160.19082.000APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
6 ARNT2interactor50.7001.667HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily
7 ARRDC3interactor21.0000Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
8 ATF2oncoprotein41.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
9 ATXN1protein found in more fusions70.4009.000AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
10 BAG6interactor80.38112.500DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
11 C10orf54interactor21.0000V-set (PF07686, IPR013106): Immunoglobulin V-set domain
12 CCDC33interactor70.4769.833C2 (PF00168, IPR000008, SM00239): C2 domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
SlyX (PF04102, IPR007236): SlyX
13 CDC42EP1oncoprotein30.6671.000DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
BORG_CEP (PF14957, IPR029273): Cdc42 effector
14 COL17A1interactor30.6671.000Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF2868 (PF11067, IPR021296): Protein of unknown function (DUF2868)
Edc3_linker (PF16598): Linker region of enhancer of mRNA-decapping protein 3
15 CPSF6interactor21.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
16 CRKoncoprotein60.5336.333SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
17 CRKLoncoprotein31.0000SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
18 DEF6interactor30.6671.000ArgK (PF03308, IPR005129): ArgK protein
HSP70 (PF00012, IPR013126): Hsp70 protein
PH (PF00169, IPR001849, SM00233): PH domain
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
EF-hand_6 (PF13405, IPR002048): EF-hand domain
19 DLK2interactor30.6670.500EGF (PF00008, IPR000742, SM00181): EGF-like domain
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
20 DSToncoprotein40.5003.000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ZYG-11_interact (PF05884, IPR008574): Interactor of ZYG-11
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain
Laminin_II (PF06009, IPR010307): Laminin Domain II
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
Phasin (PF05597, IPR008769): Poly(hydroxyalcanoate) granule associated protein (phasin)
Spectrin (PF00435, IPR002017): Spectrin repeat
Nbl1_Borealin_N (PF10444, IPR018851): Nbl1 / Borealin N terminal
XhlA (PF10779, IPR019715): Haemolysin XhlA
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
FTA4 (PF13093, IPR025207): Kinetochore complex Fta4 of Sim4 subunit, or CENP-50
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
NYD-SP28 (PF14772): Sperm tail
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
21 EGFRoncoprotein120.27338.000Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
22 EIF6interactor40.6671.667eIF-6 (PF01912, IPR002769, SM00654): eIF-6 family
23 ENPP2oncoprotein21.0000Endonuclease_NS (PF01223, IPR001604, SM00892): DNA/RNA non-specific endonuclease
Phosphodiest (PF01663, IPR002591): Type I phosphodiesterase / nucleotide pyrophosphatase
Somatomedin_B (PF01033, IPR001212, SM00201): Somatomedin B domain
24 ERBINoncoprotein60.5005.000LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
25 EWSR1oncoprotein90.28619.000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
26 FBLN1suppressor50.6671.500ANATO (PF01821, IPR000020, SM00104): Anaphylotoxin-like domain
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
27 FBXL18interactor21.0000LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
28 FRS3suppressor31.0000IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
29 GEMIN7interactor21.0000Gemin7 (PF11095, IPR020338): Gem-associated protein 7 (Gemin7)
SUZ-C (PF12901, IPR024642): SUZ-C motif
30 GLRX3interactor90.46413.000Glutaredoxin (PF00462, IPR002109): Glutaredoxin
Thioredoxin (PF00085, IPR013766): Thioredoxin
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
31 HEY2interactor30.6671.000Hairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
32 HNRNPDoncoprotein70.5336.167CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
33 HNRNPUinteractor40.6671.333CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
34 HRGsuppressor100Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
35 ILKsuppressor50.5002.333Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
36 ITGA3interactor100FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
FG-GAP_2 (PF14312, IPR013517): FG-GAP repeat
MLANA (PF14991, IPR029242): Protein melan-A
37 JUPsuppressor30.6671.000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
38 KIAA1683interactor100IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
39 KLC3interactor40.6671.000TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
TPR_12 (PF13424): Tetratricopeptide repeat
40 KRTAP10-11interactor31.0000Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
41 KRTAP10-3interactor130.31841.000Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
42 KRTAP4-11interactor41.0000Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
43 LASP1oncoprotein40.6671.667LIM (PF00412, IPR001781, SM00132): LIM domain
Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat
SH3_9 (PF14604, IPR001452): Variant SH3 domain
44 LGALS9Cinteractor100Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
45 LONRF1interactor41.0000LON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
DZR (PF12773, IPR025874): Double zinc ribbon
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
TPR_19 (PF14559): Tetratricopeptide repeat
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
46 LPAR1oncoprotein21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
47 MAPK6oncoprotein70.4008.000Pkinase (PF00069, IPR000719): Protein kinase domain
48 MVPoncoprotein50.6672.000Vault (PF01505, IPR002499): Major Vault Protein repeat
DUF2543 (PF10820, IPR020251): Protein of unknown function (DUF2543)
MVP_shoulder (PF11978, IPR021870): Shoulder domain
49 MYH13interactor100IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
50 MYO19interactor30.6671.000IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
51 NR0B2suppressor100Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
52 NTN4interactor21.0000EGF_2 (PF07974, IPR013111): EGF-like domain
NTR (PF01759, IPR018933, SM00206): UNC-6/NTR/C345C module
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI)
53 P2RY6interactor21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
54 PHLDA1oncoprotein31.0000Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
PH (PF00169, IPR001849, SM00233): PH domain
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
TonB_N (PF16031): TonB N-terminal region
55 PKD2interactor31.0000Ion_trans (PF00520, IPR005821): Ion transport protein
PKD_channel (PF08016, IPR013122): Polycystin cation channel
Tetraspannin (PF00335, IPR018499): Tetraspanin family
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
56 PLEConcoprotein50.4006.000CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
S10_plectin (PF03501, IPR005326): Plectin/S10 domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
DUF2229 (PF09989, IPR018709): CoA enzyme activase uncharacterised domain (DUF2229)
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
YlqD (PF11068, IPR021297): YlqD protein
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
57 PPP2R3Cinteractor21.0000DUF61 (PF01886, IPR002746): Protein of unknown function DUF61
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
58 RASD1interactor100Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
Ras (PF00071, IPR001806, SM00173): Ras family
59 RGS3oncoprotein21.0000C2 (PF00168, IPR000008, SM00239): C2 domain
CDC45 (PF02724, IPR003874): CDC45-like protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
Astro_capsid_p (PF12226, IPR022027): Turkey astrovirus capsid protein
60 SEL1Loncoprotein30.6671.000fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
61 SGTBinteractor21.0000TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
XPC-binding (PF09280, IPR015360): XPC-binding domain
TPR_11 (PF13414, IPR011990): TPR repeat
SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA
62 SHC1oncoprotein100.30622.667PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
63 SKIoncoprotein70.4677.667c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain
Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family
SlyX (PF04102, IPR007236): SlyX
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
64 SLC25A6interactor41.0000Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
65 SMAD2suppressor60.7002.333MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
66 SMAD3oncoprotein120.27338.667MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
67 SRConcoprotein41.0000Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
68 SREBF2protein found in more fusions40.6671.000HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
69 STK16interactor60.8001.167Pkinase (PF00069, IPR000719): Protein kinase domain
70 TNRC6Ainteractor100CreD (PF06123, IPR010364): Inner membrane protein CreD
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Ago_hook (PF10427, IPR019486): Argonaute hook
M_domain (PF12938, IPR026805): M domain of GW182
TNRC6-PABC_bdg (PF16608, IPR032226): TNRC6-PABC binding domain
71 TRIM42interactor110.42220.500CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
72 VCPprotein found in more fusions60.4006.000AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
73 VPS37Cinteractor21.0000Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
74 ZBTB16suppressor31.0000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
75 ZNF417interactor50.7003.000A2L_zn_ribbon (PF08792, IPR014900): A2L zinc ribbon domain
C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
76 ZNF581interactor30.6671.000zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
77 ZNF587interactor41.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
78 ZNF638interactor100RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
zf-met (PF12874): Zinc-finger of C2H2 type
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ADCY7interactorDUF1053 (PF06327, IPR009398): Domain of Unknown Function (DUF1053)
Guanylate_cyc (PF00211, IPR001054, SM00044): Adenylate and Guanylate cyclase catalytic domain
AC_N (PF16214, IPR032628): Adenylyl cyclase N-terminal extracellular and transmembrane region
DUF4956 (PF16316, IPR032531): Domain of unknown function (DUF4956)
2 ATG12interactorAPG12 (PF04110, IPR007242): Ubiquitin-like autophagy protein Apg12
3 ATN1interactorAtrophin-1 (PF03154, IPR002951): Atrophin-1 family
4 BCL6BsuppressorBTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
Lar_restr_allev (PF14354): Restriction alleviation protein Lar
5 C10orf10interactorDEPP (PF15343, IPR020133): Decidual protein induced by progesterone family
6 C10orf62interactorNA
7 CATSPER1interactorIon_trans (PF00520, IPR005821): Ion transport protein
MMM1 (PF10296, IPR019411): Maintenance of mitochondrial morphology protein 1
8 CCER1interactorVfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Neugrin (PF06413, IPR010487): Neugrin
CCER1 (PF15482, IPR027889): Coiled-coil domain-containing glutamate-rich protein family 1
9 CHRDinteractorCHRD (PF07452, IPR010895, SM00754): CHRD domain
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
10 CNTFRinteractorfn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ig_3 (PF13927): Immunoglobulin domain
CBP_CCPA (PF17040, IPR031480): Cellulose-complementing protein A
11 CPSF3LinteractorRMMBL (PF07521, IPR011108): Zn-dependent metallo-hydrolase RNA specificity domain
Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain
Lactamase_B_3 (PF13483): Beta-lactamase superfamily domain
Lactamase_B_6 (PF16661, IPR001279): Metallo-beta-lactamase superfamily domain
12 CRY1interactorDNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
13 CTBP1-AS2interactorNA
14 CTSZinteractorPeptidase_C1 (PF00112, IPR000668, SM00645): Papain family cysteine protease
15 DAZAP2interactorDAZAP2 (PF11029, IPR022730): DAZ associated protein 2 (DAZAP2)
16 DHRS1interactoradh_short (PF00106, IPR002198): short chain dehydrogenase
17 DMRT3interactorDM (PF00751, IPR001275, SM00301): DM DNA binding domain
DMA (PF03474, IPR005173): DMRTA motif
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
18 DOCK2oncoproteinDHR-2 (PF06920, IPR010703): Dock homology region 2
DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539)
DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins
SH3_9 (PF14604, IPR001452): Variant SH3 domain
DOCK_N (PF16172, IPR032376): DOCK N-terminus
19 DTX2oncoproteinWWE (PF02825, IPR004170, SM00678): WWE domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-UDP (PF14569, IPR027934): Zinc-binding RING-finger
20 EFEMP2interactorEGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Adipogenin (PF15202, IPR027938): Adipogenin
21 ENKD1interactorEnkurin (PF13864, IPR027012): Calmodulin-binding
22 EP300oncoproteinCreb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
23 ESR2suppressorzf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ERbeta_N (PF12497, IPR021064): Estrogen receptor beta
24 EXD3interactorDNA_pol_A_exo1 (PF01612, IPR002562, SM00474): 3'-5' exonuclease
Mut7-C (PF01927, IPR002782): Mut7-C RNAse domain
25 FAM103A1interactorRAM (PF15320, IPR028271): mRNA cap methylation, RNMT-activating mini protein
26 FAM134CinteractorReticulon (PF02453, IPR003388): Reticulon
27 FRAT1oncoproteinGSK-3_bind (PF05350, IPR008014): Glycogen synthase kinase-3 binding
28 GDE1interactorGDPD (PF03009, IPR004129): Glycerophosphoryl diester phosphodiesterase family
29 GDPD5interactorDUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
GDPD (PF03009, IPR004129): Glycerophosphoryl diester phosphodiesterase family
MgtE (PF01769, IPR006667): Divalent cation transporter
GDPD_2 (PF13653): Glycerophosphoryl diester phosphodiesterase family
30 GNAI2oncoproteinG-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
31 GPRIN2interactorGRIN_C (PF15235, IPR032745): G protein-regulated inducer of neurite outgrowth C-terminus
32 HOXA1interactorHomeobox (PF00046, IPR001356, SM00389): Homeobox domain
33 HOXA9oncoproteinHox9_act (PF04617, IPR006711): Hox9 activation region
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
34 HOXB6interactorHomeobox (PF00046, IPR001356, SM00389): Homeobox domain
35 ILF3oncoproteindsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
36 IP6K2interactorIPK (PF03770, IPR005522): Inositol polyphosphate kinase
37 ITGB4parental proteinCalx-beta (PF03160, IPR003644, SM00237): Calx-beta domain
EGF_2 (PF07974, IPR013111): EGF-like domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
SEA (PF01390, IPR000082, SM00200): SEA domain
STOP (PF05217, IPR024963): STOP protein
Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain
PSI_integrin (PF17205): Integrin plexin domain
38 KIF1AinteractorFHA (PF00498, IPR000253, SM00240): FHA domain
IncA (PF04156, IPR007285): IncA protein
PH (PF00169, IPR001849, SM00233): PH domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
KIF1B (PF12423, IPR022140): Kinesin protein 1B
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
DUF3694 (PF12473, IPR022164): Kinesin protein
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
39 KRTAP10-9interactorKeratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
40 KRTAP4-12interactorKeratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
41 KRTAP4-2interactorKeratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
42 KRTAP5-6interactorNA
43 KRTAP9-2interactorKeratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
44 LCE2DinteractorLCE (PF14672, IPR028205): Late cornified envelope
45 LCE3CinteractorLCE (PF14672, IPR028205): Late cornified envelope
46 LCE4AinteractorLCE (PF14672, IPR028205): Late cornified envelope
47 LINC00663interactorNA
48 LINC01547interactorNA
49 MED15interactorMed15 (PF09606, IPR019087): ARC105 or Med15 subunit of Mediator complex non-fungal
50 MGAT5BinteractorGlyco_transf_18 (PF15024): Glycosyltransferase family 18
51 NECAP2interactorDUF1681 (PF07933, IPR012466): Protein of unknown function (DUF1681)
52 NEU4interactorBNR_2 (PF13088, IPR011040): BNR repeat-like domain
53 NOC4LinteractorCBF (PF03914, IPR005612, SM00521): CBF/Mak21 family
54 NPDC1interactorNPDC1 (PF06809, IPR009635): Neural proliferation differentiation control-1 protein (NPDC1)
55 OGDHinteractorE1_dh (PF00676, IPR001017): Dehydrogenase E1 component
Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
2-oxogl_dehyd_N (PF16078, IPR032106): 2-oxoglutarate dehydrogenase N-terminus
OxoGdeHyase_C (PF16870, IPR031717): 2-oxoglutarate dehydrogenase C-terminal
56 PCED1AinteractorPC-Esterase (PF13839, IPR026057): GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p
57 PGLSinteractorGlucosamine_iso (PF01182, IPR006148): Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
58 PITX1oncoproteinForkhead_N (PF08430, IPR013638): Forkhead N-terminal region
OAR (PF03826, IPR003654): OAR domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
59 PLSCR1parental proteinScramblase (PF03803, IPR005552): Scramblase
60 PLSCR3interactorScramblase (PF03803, IPR005552): Scramblase
61 PLSCR4interactorScramblase (PF03803, IPR005552): Scramblase
62 PMLsuppressorzf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
63 PRR13interactorDUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
64 RBL1suppressorRB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
65 REREoncoproteinAtrophin-1 (PF03154, IPR002951): Atrophin-1 family
BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
POPLD (PF08170, IPR012590): POPLD (NUC188) domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
66 SCNM1interactorzf-SCNM1 (PF15803, IPR031622): Zinc-finger of sodium channel modifier 1
SCNM1_acidic (PF15805, IPR031625): Acidic C-terminal region of sodium channel modifier 1 SCNM1
67 SF1interactorUPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181)
zf-CCHC (PF00098, IPR001878): Zinc knuckle
KH_1 (PF00013, IPR004088, SM00322): KH domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain
68 SLC35A2interactorNuc_sug_transp (PF04142, IPR007271): Nucleotide-sugar transporter
69 SLPIinteractorBES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal
WAP (PF00095, IPR008197, SM00217): WAP-type (Whey Acidic Protein) 'four-disulfide core'
70 SMARCC1suppressorSWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
71 SMCPinteractorDUF2650 (PF10853, IPR022559): Protein of unknown function (DUF2650)
72 SPATA8interactorNA
73 SPG7oncoproteinAAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
FtsH_ext (PF06480, IPR011546): FtsH Extracellular
Peptidase_M41 (PF01434, IPR000642): Peptidase family M41
AAA_22 (PF13401, IPR003593): AAA domain
74 SPRY2suppressorKAR9 (PF08580, IPR013889): Yeast cortical protein KAR9
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
75 TFGoncoproteinARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
MucBP (PF06458, IPR009459): MucBP domain
PB1 (PF00564, IPR000270, SM00666): PB1 domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
76 VASPinteractorASD2 (PF08687, IPR014799): Apx/Shroom domain ASD2
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
77 YIPF3interactorYip1 (PF04893, IPR006977): Yip1 domain
DUF4133 (PF13571, IPR025407): Domain of unknown function (DUF4133)
78 ZNF764interactorKRAB (PF01352, IPR001909, SM00349): KRAB box
PHD (PF00628, IPR019787, SM00249): PHD-finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF2256 (PF10013, IPR017136): Uncharacterized protein conserved in bacteria (DUF2256)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger

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