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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: AW362574 is the fusion of parental proteins COL4A2, ENO1 (from a repository: Thu Dec 8 13:38:23 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)303
The number (and %) of the onco-proteins69 (22.77 %)
The number (and %) of the tumor suppressors40 (13.20 %)
Total number of binary PPIs (saturation %)2404 (5.25 %)
The number (and %) of affected PPIs302 (12.56 %)
The number of possible different fusions46
PPI diameter2
PPI radius1
The average degree of PPI15.162
Assortativity coefficient-0.2772
The network average Clustering coefficient0.455
The number (and %) of a zero Clustering coefficients43 (14.19 %)
The number (and %) of a zero Betweenness Centrality79 (26.07 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: ENO1,COL4A2 All fusions
: AW362574;
Proteins found in more fusions PRPF19 (see 2 fusions); NPM1 (see 1 fusions); CUL1 (see 3 fusions); COPB1 (see 2 fusions); GRB2 (see 1 fusions); FYN (see 1 fusions); VHL (see 1 fusions); MPHOSPH8 (see 5 fusions); YWHAZ (see 1 fusions); FANCA (see 1 fusions); PCNA (see 1 fusions); VPS35 (see 2 fusions); CUL4A (see 4 fusions); TKT (see 5 fusions); HUWE1 (see 2 fusions); COPS5/HNRNPH3 (see 3 fusions); HINT1 (see 3 fusions); COL4A1 (see 3 fusions); UBAP1 (see 2 fusions); CALR (see 6 fusions); HNRNPD (see 1 fusions); EZR (see 2 fusions); STUB1 (see 1 fusions); CHD3 (see 1 fusions); SOD1/TAGLN2 (see 1 fusions); GAPDH (see 2 fusions); PPFIBP1 (see 1 fusions); STAU1 (see 2 fusions); HNRNPH3 (see 1 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); IVNS1ABP (see 2 fusions); BCAP31 (see 3 fusions); ITPA (see 1 fusions); COPS5 (see 1 fusions); DHX8 (see 1 fusions); MYO6 (see 3 fusions); THRA (see 3 fusions); LMNA (see 3 fusions); NAP1L4 (see 3 fusions); PRDX4 (see 1 fusions); SH3KBP1 (see 1 fusions); MCM2 (see 1 fusions); CFL1/EED (see 1 fusions); DAZAP2 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AW362574chimera3020.04466432.120C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
2 AARSinteractor70.4291.180DHHA1 (PF02272, IPR003156): DHHA1 domain
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
tRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
3 ABATinteractor70.4762.758Aminotran_3 (PF00202, IPR005814): Aminotransferase class-III
4 ABI2suppressor41.0000Abi_HHR (PF07815, IPR012849): Abl-interactor HHR
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
SH3_9 (PF14604, IPR001452): Variant SH3 domain
TMEM171 (PF15471, IPR029173): Transmembrane protein family 171
ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension
5 ACAA2interactor200.41154.097Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
6 ACACAinteractor80.6431.694ACC_central (PF08326, IPR013537): Acetyl-CoA carboxylase, central region
Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain
Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
DUF445 (PF04286, IPR007383): Protein of unknown function (DUF445)
7 ACO1interactor31.0000Aconitase (PF00330, IPR001030): Aconitase family (aconitate hydratase)
Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
8 AGTPBP1interactor100Peptidase_M14 (PF00246, IPR000834, SM00631): Zinc carboxypeptidase
V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H
9 AHSA1interactor140.56013.025Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal
AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
10 AKR1B1suppressor230.42360.209Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
11 AKR1B15interactor80.8570.563Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
12 AKT1oncoprotein150.33025.233PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
13 ALDH4A1interactor80.7141.100Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family
14 ALDOAinteractor450.270326.263Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
15 AMBPinteractor41.0000Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
16 ANKRD40interactor31.0000Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
17 ANXA1suppressor210.41140.782Annexin (PF00191, IPR018502, SM00335): Annexin
18 ANXA7suppressor130.23131.571Annexin (PF00191, IPR018502, SM00335): Annexin
19 ARPC4interactor80.4298.939ARPC4 (PF05856, IPR008384): ARP2/3 complex 20 kDa subunit (ARPC4)
20 ASCC3interactor50.6001.469DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
PhoH (PF02562, IPR003714): PhoH-like protein
Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
21 ATF2oncoprotein180.39722.171bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
22 ATP5Jinteractor60.5332.525ATP-synt_F6 (PF05511, IPR008387): Mitochondrial ATP synthase coupling factor 6
23 ATP6AP2interactor50.5002.222Phosphodiest (PF01663, IPR002591): Type I phosphodiesterase / nucleotide pyrophosphatase
Renin_r (PF07850, IPR012493): Renin receptor-like protein
24 BCAP31protein found in more fusions60.6001.169Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
25 BHLHE40interactor50.6671.400Hairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
26 BIN1suppressor31.0000BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
27 BRCA1suppressor300.241167.280BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
28 BTRConcoprotein190.19681.232WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
29 C14orf1interactor50.4002.700Erg28 (PF03694, IPR005352): Erg28 like protein
30 C1QBinteractor50.6001.661C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
31 C1QTNF2interactor30.6670.500C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
32 C1QTNF9oncoprotein100C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
33 C8orf33interactor60.5333.952DUF4615 (PF15393, IPR029274): Domain of unknown function (DUF4615)
34 CALRoncoprotein220.42934.620Calreticulin (PF00262, IPR001580): Calreticulin family
DDHD (PF02862, IPR004177, SM01127): DDHD domain
35 CAND1interactor500.319316.312Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
36 CATsuppressor110.6443.602Catalase (PF00199, IPR011614, SM01060): Catalase
Catalase-rel (PF06628, IPR010582): Catalase-related immune-responsive
37 CCDC8interactor370.257222.465Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
38 CCT7interactor250.27782.365Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
39 CD4suppressor90.4644.193ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family
C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
CD4-extracel (PF09191, IPR015274): CD4, extracellular
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region
40 CDC42SE1interactor100PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
41 CDK2suppressor640.222707.304Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
42 CELA2Binteractor100Trypsin (PF00089, IPR001254, SM00020): Trypsin
43 CEP192interactor100Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
TMEM131_like (PF12371, IPR022113): Transmembrane protein 131-like
MYCBPAP (PF14646, IPR032707): MYCBP-associated protein family
ASH (PF15780, IPR031549): Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
44 CEP250interactor140.34121.433ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
EHN (PF06441, IPR010497): Epoxide hydrolase N terminus
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
45 CFL1protein found in more fusions390.350191.729Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
46 CHD3oncoprotein130.30330.909CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
FAM176 (PF14851): FAM176 family
47 CHEK2suppressor80.4764.042FHA (PF00498, IPR000253, SM00240): FHA domain
Pkinase (PF00069, IPR000719): Protein kinase domain
48 CLK1interactor120.29122.487PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
Pkinase (PF00069, IPR000719): Protein kinase domain
49 CLPSL1interactor100Toxin_3 (PF00537, IPR002061): Scorpion toxin-like domain
50 CLTCL1oncoprotein70.7142.202Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat
Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
Clathrin_H_link (PF13838): Clathrin-H-link
51 COL4A1protein found in more fusions31.0000C4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
52 COL8A2interactor21.0000C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
53 COL9A1interactor21.0000Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF826 (PF05696, IPR008544): Protein of unknown function (DUF826)
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
54 COPB1protein found in more fusions120.6184.127Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Coatamer_beta_C (PF07718, IPR011710): Coatomer beta C-terminal region
Coatomer_b_Cpla (PF14806, IPR029446): Coatomer beta subunit appendage platform
55 COPS5protein found in more fusions440.354176.760JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
56 CPSF7interactor140.38523.094CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
57 CPT1Ainteractor40.8330.067Carn_acyltransf (PF00755, IPR000542): Choline/Carnitine o-acyltransferase
CPT_N (PF16484, IPR032476): Carnitine O-palmitoyltransferase N-terminus
58 CRLF1interactor100EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Lep_receptor_Ig (PF06328, IPR010457): Ig-like C2-type domain
59 CSNK2Binteractor170.33332.250CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
60 CUL1suppressor460.307269.887Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
61 CUL2suppressor330.38692.251Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
62 CUL3protein found in more fusions720.1881028.980Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
63 CUL4Aprotein found in more fusions200.57325.129Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
64 CUL4Boncoprotein340.424103.209Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
65 CUL5suppressor310.43983.591Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
66 CUL7protein found in more fusions590.170514.715ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
67 CYB5Binteractor30.6670.667Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain
MIP (PF00230, IPR000425): Major intrinsic protein
68 CYB5R3interactor30.6670.667FAD_binding_6 (PF00970, IPR008333): Oxidoreductase FAD-binding domain
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
69 DAZAP2protein found in more fusions40.6671.000DAZAP2 (PF11029, IPR022730): DAZ associated protein 2 (DAZAP2)
70 DCLK2interactor100DCX (PF03607, IPR003533, SM00537): Doublecortin
Metallothio_Pro (PF02069, IPR000518): Prokaryotic metallothionein
Pkinase (PF00069, IPR000719): Protein kinase domain
71 DCPSinteractor70.5714.362DcpS (PF05652, IPR008594): Scavenger mRNA decapping enzyme (DcpS) N-terminal
DcpS_C (PF11969): Scavenger mRNA decapping enzyme C-term binding
72 DEDDinteractor200DED (PF01335, IPR001875, SM00031): Death effector domain
73 DHX15interactor370.372140.811DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AAA_29 (PF13555): P-loop containing region of AAA domain
74 DHX30interactor200.43732.024Bombolitin (PF08096, IPR012534): Bombolitin family
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
75 DHX8protein found in more fusions80.8100.389DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
76 DIAPH3interactor21.0000Drf_DAD (PF06345, IPR010465): DRF Autoregulatory Domain
Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain
Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
POX (PF07526, IPR006563, SM00574): Associated with HOX
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
77 DPH5interactor100TP_methylase (PF00590, IPR000878): Tetrapyrrole (Corrin/Porphyrin) Methylases
78 DUTinteractor180.51625.673dUTPase (PF00692, IPR008180): dUTPase
79 E2F4suppressor40.8330.222E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
SPX (PF03105, IPR004331): SPX domain
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
80 EBPinteractor100Phage_holin_3_6 (PF07332, IPR009937): Putative Actinobacterial Holin-X, holin superfamily III
EBP (PF05241, IPR007905): Emopamil binding protein
81 EEDsuppressor350.209176.234WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
82 EEF1B2interactor210.35831.486EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
GST_C_6 (PF17171): Glutathione S-transferase, C-terminal domain
83 EEF2interactor340.390107.003EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
84 EFEMP1interactor100EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
85 EMC1interactor60.5331.570DUF1620 (PF07774, IPR011678): Protein of unknown function (DUF1620)
PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
PQQ_2 (PF13360, IPR002372): PQQ-like domain
86 ENDOD1interactor100DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
Endonuclease_NS (PF01223, IPR001604, SM00892): DNA/RNA non-specific endonuclease
87 ENO2interactor450.301311.219Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
88 ENO3interactor330.341162.048Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
89 ERAP1interactor100Peptidase_M1 (PF01433, IPR014782): Peptidase family M1
ERAP1_C (PF11838, IPR024571): ERAP1-like C-terminal domain
90 EZRprotein found in more fusions280.38567.879DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
91 FABP5interactor210.50036.752Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
92 FAF2interactor140.33331.133DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
UBX (PF00789, IPR001012, SM00166): UBX domain
Thioredoxin_7 (PF13899): Thioredoxin-like
UBA_4 (PF14555): UBA-like domain
93 FAM46Ainteractor21.0000NTP_transf_7 (PF07984, IPR012937, SM01153): Nucleotidyltransferase
94 FANCAoncoprotein70.7330.738Fanconi_A (PF03511, IPR003516): Fanconi anaemia group A protein
Fanconi_A_N (PF15865, IPR031729): Fanconi anaemia group A protein N terminus
95 FARS2interactor40.6670.354FDX-ACB (PF03147, IPR005121, SM00896): Ferredoxin-fold anticodon binding domain
tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N)
tRNA-synt_2d (PF01409, IPR002319): tRNA synthetases class II core domain (F)
96 FAT4suppressor100EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
FOLN (PF09289, IPR015369, SM00274): Follistatin/Osteonectin-like EGF domain
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Cadherin_3 (PF16184): Cadherin-like
97 FBLinteractor220.39043.479Fibrillarin (PF01269, IPR000692): Fibrillarin
98 FBXO25suppressor100.4229.801Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
99 FBXO5oncoprotein40.5002.067IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
F-box (PF00646, IPR001810, SM00256): F-box domain
100 FBXO6interactor360.198237.215FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
101 FBXW7suppressor80.3339.555Mem_trans (PF03547, IPR004776): Membrane transport protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
F-box-like (PF12937, IPR001810): F-box-like
102 FGL1interactor21.0000Fibrinogen_C (PF00147, IPR002181, SM00186): Fibrinogen beta and gamma chains, C-terminal globular domain
103 FHsuppressor150.41022.321Lyase_1 (PF00206, IPR022761): Lyase
FumaraseC_C (PF10415, IPR018951): Fumarase C C-terminus
104 FKBP1Ainteractor180.6997.994FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
Hemopexin (PF00045, IPR018487, SM00120): Hemopexin
105 FKBP1Binteractor130.7057.428FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
106 FKBP2interactor200.43748.880FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
107 FKBP7interactor80.6433.067FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
108 FLNCinteractor100.5114.954CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
PapC_N (PF13954, IPR025885): PapC N-terminal domain
109 FN1oncoprotein640.174788.679fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
110 FUSsuppressor450.415177.783Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
111 FYNoncoprotein80.38111.067Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
112 GAPDHoncoprotein570.270462.762Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
113 GATAD1interactor31.0000GATA (PF00320, IPR000679, SM00401): GATA zinc finger
114 GIPC3interactor100PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
115 GPIinteractor200.33252.110PGI (PF00342, IPR001672): Phosphoglucose isomerase
116 GPX4interactor160.6588.921GSHPx (PF00255, IPR000889): Glutathione peroxidase
117 GRB2oncoprotein280.316128.667SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
118 GSTM3interactor200GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
119 H2AFXsuppressor320.268133.575Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
120 HDAC1suppressor230.251100.324FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
121 HDAC2suppressor210.28458.880Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
122 HDGFinteractor180.24842.035PWWP (PF00855, IPR000313, SM00293): PWWP domain
123 HEMGNinteractor31.0000BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
124 HINT1suppressor260.41780.967HIT (PF01230, IPR001310): HIT domain
125 HIST1H2BGoncoprotein120.28826.248Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
126 HIST1H4Ioncoprotein140.3637.160CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
127 HIST2H2ABinteractor50.5002.222Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
128 HNRNPA1interactor670.286630.829RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
129 HNRNPDoncoprotein370.386113.121CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
130 HNRNPH3protein found in more fusions250.39143.056Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
131 HNRNPMinteractor270.39067.520RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
132 HSD17B10interactor440.292288.345adh_short (PF00106, IPR002198): short chain dehydrogenase
133 HSPA9oncoprotein420.343190.727HSP70 (PF00012, IPR013126): Hsp70 protein
134 HSPB2interactor100.3069.540Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
135 HUWE1oncoprotein360.294146.961BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
136 IFRD2oncoprotein21.0000IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD)
IFRD_C (PF04836, IPR006921): Interferon-related protein conserved region
137 INSIG2interactor21.0000INSIG (PF07281, IPR025929): Insulin-induced protein (INSIG)
138 IPO4interactor60.6002.772HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis
UME (PF08064, IPR012993, SM00802): UME (NUC010) domain
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
139 ISG15suppressor200.28954.658ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
140 ISOC2interactor40.6670.167Isochorismatase (PF00857, IPR000868): Isochorismatase family
141 ITGA4interactor500.236316.510FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
142 ITLN2interactor100Fibrinogen_C (PF00147, IPR002181, SM00186): Fibrinogen beta and gamma chains, C-terminal globular domain
143 ITPAprotein found in more fusions90.3576.588Ham1p_like (PF01725, IPR002637): Ham1 family
144 IVNS1ABPprotein found in more fusions120.41815.659BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
145 IWS1interactor40.5001.071DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
146 KANK1suppressor100DegQ (PF08181, IPR012554): DegQ (SacQ) family
ZapB (PF06005, IPR009252): Cell division protein ZapB
Com_YlbF (PF06133, IPR010368): Control of competence regulator ComK, YlbF/YmcA
Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
KN_motif (PF12075, IPR021939): KN motif
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
147 KIF23interactor70.4295.758DUF730 (PF05325, IPR007989): Protein of unknown function (DUF730)
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
MKLP1_Arf_bdg (PF16540, IPR032384): Arf6-interacting domain of mitotic kinesin-like protein 1
148 KLHDC3interactor31.0000Kelch_2 (PF07646, IPR011498): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_4 (PF13418): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
Kelch_6 (PF13964): Kelch motif
149 KNSTRNinteractor21.0000FlpD (PF02662, IPR003813): Methyl-viologen-reducing hydrogenase, delta subunit
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Matrilin_ccoil (PF10393, IPR019466): Trimeric coiled-coil oligomerisation domain of matrilin
150 LDHAinteractor490.309293.202Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
151 LDHBinteractor410.344180.162Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
152 LETMD1interactor100LETM1 (PF07766, IPR011685): LETM1-like protein
153 LIG4interactor110.4736.869APG17 (PF04108, IPR007240): Autophagy protein Apg17
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region
DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain
DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus
DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
154 LMNAprotein found in more fusions290.38474.529Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
155 LRRC42interactor21.0000LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
156 LUC7L3interactor140.43612.354LUC7 (PF03194, IPR004882): LUC7 N_terminus
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
157 M6PRinteractor21.0000Man-6-P_recep (PF02157, IPR028927): Mannose-6-phosphate receptor
158 MAP2K5oncoprotein41.0000PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
159 MBNL2interactor100zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
Torus (PF16131, IPR032297): Torus domain
160 MCM2oncoprotein750.229921.621AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
161 MCM5oncoprotein240.41773.563MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
162 MDC1suppressor180.35943.320FHA (PF00498, IPR000253, SM00240): FHA domain
DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274)
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
163 MED29interactor31.0000Med29 (PF11568, IPR021018): Mediator complex subunit 29
164 MIFoncoprotein190.43829.953MIF (PF01187, IPR001398): Macrophage migration inhibitory factor (MIF)
165 MORC4interactor21.0000zf-CW (PF07496, IPR011124): CW-type Zinc Finger
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
166 MPDZinteractor30.6670.500L27_2 (PF09045, IPR015132): L27_2
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
MPDZ_u10 (PF16667, IPR032078): Unstructured region 10 on multiple PDZ protein
167 MPHOSPH8protein found in more fusions40.6670.500Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_5 (PF13857): Ankyrin repeats (many copies)
YqzE (PF14038, IPR025622): YqzE-like protein
168 MRPL37interactor110.45515.159PDCD9 (PF07147, IPR010793): Mitochondrial 28S ribosomal protein S30 (PDCD9)
169 MSNoncoprotein310.356107.200DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
170 MTFR1interactor100Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
171 MVKinteractor200GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal
GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
GalKase_gal_bdg (PF10509, IPR019539): Galactokinase galactose-binding signature
172 MYO18Ainteractor110.30925.801Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
173 MYO1Einteractor50.6002.233IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
174 MYO6protein found in more fusions70.4672.897BUD22 (PF09073, IPR015158): BUD22
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Rad9 (PF04139, IPR007268): Rad9
Sec62 (PF03839, IPR004728): Translocation protein Sec62
XhlA (PF10779, IPR019715): Haemolysin XhlA
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887)
Myosin-VI_CBD (PF16521, IPR032412): Myosin VI cargo binding domain
175 MYOCinteractor70.8001.833IncA (PF04156, IPR007285): IncA protein
OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain
176 NAB1interactor100Nab1 (PF04902, IPR006986): Conserved region in Nab1
NCD1 (PF04904, IPR006988): NAB conserved region 1 (NCD1)
NCD2 (PF04905, IPR006989): NAB conserved region 2 (NCD2)
177 NAP1L4protein found in more fusions90.7861.540NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
178 NAXDinteractor40.6672.000Carb_kinase (PF01256, IPR000631): Carbohydrate kinase
GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
179 NCAPD3interactor31.0000DUF3013 (PF11217, IPR021380): Protein of unknown function (DUF3013)
CLASP_N (PF12348, IPR024395): CLASP N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Cnd3 (PF12719, IPR025977): Nuclear condensing complex subunits, C-term domain
180 NFATC3oncoprotein100DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
181 NIPSNAP1interactor70.5712.412NIPSNAP (PF07978, IPR012577): NIPSNAP
182 NIT2suppressor60.8670.733CN_hydrolase (PF00795, IPR003010): Carbon-nitrogen hydrolase
183 NME1-NME2interactor210.54330.552NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
184 NME2interactor190.62114.402NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
185 NOP56interactor190.50323.785Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
186 NPLOC4interactor80.5006.464NPL4 (PF05021, IPR007717): NPL4 family
zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region
UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
187 NPM1suppressor560.253520.093Nucleoplasmin (PF03066): Nucleoplasmin
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
188 NTN4interactor100EGF_2 (PF07974, IPR013111): EGF-like domain
NTR (PF01759, IPR018933, SM00206): UNC-6/NTR/C345C module
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI)
189 NTRK1oncoprotein1150.1223621.180I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
190 NUDCinteractor110.34515.474CS (PF04969, IPR007052): CS domain
D5_N (PF08706, IPR014818, SM00885): D5 N terminal like
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Nudc_N (PF14050, IPR025934): N-terminal conserved domain of Nudc.
NuDC (PF16273, IPR032572): Nuclear distribution C domain
191 NUMA1oncoprotein150.47622.369Colicin (PF01024, IPR000293): Colicin pore forming domain
Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848)
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
192 NUP205interactor120.4243.471Nup192 (PF11894, IPR021827): Nuclear pore complex scaffold, nucleoporins 186/192/205
193 OBSL1interactor500.211285.686BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
194 OGDHinteractor50.6001.569E1_dh (PF00676, IPR001017): Dehydrogenase E1 component
Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
2-oxogl_dehyd_N (PF16078, IPR032106): 2-oxoglutarate dehydrogenase N-terminus
OxoGdeHyase_C (PF16870, IPR031717): 2-oxoglutarate dehydrogenase C-terminal
195 OSBPL3oncoprotein100Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein
PH_8 (PF15409): Pleckstrin homology domain
196 P4HBinteractor280.40759.634Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
197 PARK7suppressor180.28756.312DJ-1_PfpI (PF01965, IPR002818): DJ-1/PfpI family
198 PCMT1interactor280.31098.536PCMT (PF01135, IPR000682): Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
199 PCNAoncoprotein340.369107.067PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
200 PDCD6IPinteractor190.32750.032BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
201 PDPRinteractor50.9000.500DAO (PF01266, IPR006076): FAD dependent oxidoreductase
GCV_T (PF01571, IPR006222): Aminomethyltransferase folate-binding domain
GCV_T_C (PF08669, IPR013977): Glycine cleavage T-protein C-terminal barrel domain
Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
FAO_M (PF16350, IPR032503): FAD dependent oxidoreductase central domain
202 PEF1interactor70.3819.827EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
203 PGAM1interactor140.58210.747His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
204 PGK1interactor320.45268.843PGK (PF00162, IPR001576): Phosphoglycerate kinase
205 PGK2interactor50.7000.576PGK (PF00162, IPR001576): Phosphoglycerate kinase
206 PGM1interactor140.46220.271PGM_PMM_I (PF02878, IPR005844): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
PGM_PMM_II (PF02879, IPR005845): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
PGM_PMM_III (PF02880, IPR005846): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
PGM_PMM_IV (PF00408, IPR005843): Phosphoglucomutase/phosphomannomutase, C-terminal domain
207 PITPNBinteractor50.8000.361IP_trans (PF02121, IPR001666): Phosphatidylinositol transfer protein
208 PLGinteractor30.6670.667Kringle (PF00051, IPR000001): Kringle domain
PAN_1 (PF00024, IPR003014): PAN domain
Trypsin (PF00089, IPR001254, SM00020): Trypsin
209 PMP2interactor60.8670.235Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
210 PMPCBinteractor100Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
211 PNPinteractor70.7330.595PNP_UDP_1 (PF01048, IPR000845): Phosphorylase superfamily
212 POFUT1interactor50.6000.968O-FucT (PF10250, IPR019378): GDP-fucose protein O-fucosyltransferase
213 POGZinteractor50.6003.200DDE_1 (PF03184, IPR004875): DDE superfamily endonuclease
Rubredoxin (PF00301, IPR024935): Rubredoxin
HTH_Tnp_Tc5 (PF03221, IPR006600, SM00674): Tc5 transposase DNA-binding domain
zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
HTH_28 (PF13518): Helix-turn-helix domain
zinc_ribbon_4 (PF13717): zinc-ribbon domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
214 POLA1interactor50.9000.095DNA_pol_B (PF00136, IPR006134): DNA polymerase family B
DNA_pol_B_exo1 (PF03104, IPR006133): DNA polymerase family B, exonuclease domain
zf-DNA_Pol (PF08996, IPR015088): DNA Polymerase alpha zinc finger
DNA_pol_alpha_N (PF12254, IPR024647): DNA polymerase alpha subunit p180 N terminal
215 POLE3interactor100BUD22 (PF09073, IPR015158): BUD22
CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone
216 POLR1Ainteractor21.0000RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
217 PPFIBP1oncoprotein70.6002.371DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
XkdW (PF09636, IPR019094): XkdW protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF3837 (PF12939, IPR024212): Domain of unknown function (DUF3837)
218 PPIAinteractor290.38966.211Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
219 PPIBinteractor230.34472.158Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
220 PPP5Cinteractor90.5835.199Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
PPP5 (PF08321, IPR013235): PPP5 TPR repeat region
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
221 PRDX4protein found in more fusions100.5008.194AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
222 PRPF19protein found in more fusions230.40759.487Prp19 (PF08606, IPR013915): Prp19/Pso4-like
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
223 PSMA3interactor290.331107.091Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
224 PTPN9interactor30.6670.222CRAL_TRIO_N (PF03765, IPR011074, SM01100): CRAL/TRIO, N-terminal domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
CRAL_TRIO (PF00650, IPR001251, SM00516): CRAL/TRIO domain
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
225 PTPRKsuppressor40.6671.167fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu
Protocadherin (PF08374, IPR013585): Protocadherin
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
226 PUS7interactor70.6673.892R3H (PF01424, IPR001374, SM00393): R3H domain
TruD (PF01142, IPR001656): tRNA pseudouridine synthase D (TruD)
227 QRICH1interactor31.0000CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
DUF3504 (PF12012, IPR021893): Domain of unknown function (DUF3504)
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
228 RAB34oncoprotein100Ras (PF00071, IPR001806, SM00173): Ras family
229 RAD52oncoprotein70.5330.670Rad52_Rad22 (PF04098, IPR007232): Rad52/22 family double-strand break repair protein
DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335)
230 RAPGEF6interactor21.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
231 RBM25interactor80.5362.284Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
PWI (PF01480, IPR002483, SM00311): PWI domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
DUF3441 (PF11923, IPR021846): Domain of unknown function (DUF3441)
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4778 (PF16008, IPR031958): Domain of unknown function (DUF4778)
232 RBMS2interactor21.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PHM7_cyt (PF14703, IPR027815): Cytosolic domain of 10TM putative phosphate transporter
233 RCC1interactor100.4676.742RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
234 RCN1interactor120.54513.636EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
235 RDXinteractor160.51721.528ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
236 RHOFoncoprotein100Ras (PF00071, IPR001806, SM00173): Ras family
237 RNF10interactor21.0000GCS2 (PF04107, IPR006336): Glutamate-cysteine ligase family 2(GCS2)
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
238 SCAF8interactor30.6670.125DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
DUF3525 (PF12039, IPR021912): Protein of unknown function (DUF3525)
YebO (PF13974, IPR025594): YebO-like protein
CNDH2_M (PF16869): PF16858
239 SCARA3interactor50.4005.667Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
Filament (PF00038, IPR001664): Intermediate filament protein
Flagellin_C (PF00700, IPR001029): Bacterial flagellin C-terminal helical region
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
zf-C2H2_10 (PF16588, IPR001878): C2H2 zinc-finger
240 SEMG1interactor21.0000Semenogelin (PF05474, IPR008836): Semenogelin
241 SERPINA6interactor21.0000Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
242 SERPING1interactor100PT (PF04886, IPR006970): PT repeat
Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
243 SF3A1interactor170.46317.679TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Surp (PF01805, IPR000061, SM00648): Surp module
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
244 SH3KBP1protein found in more fusions130.24232.391Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein
SH3_9 (PF14604, IPR001452): Variant SH3 domain
245 SKILsuppressor80.3339.117c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain
DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family
DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115)
246 SLC25A39interactor100Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
247 SMARCE1interactor60.4672.642DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1)
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
248 SMN1interactor150.35223.680SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
249 SNRNP25interactor21.0000ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
250 SOD1protein found in more fusions330.282175.159Sod_Cu (PF00080, IPR001424): Copper/zinc superoxide dismutase (SODC)
251 SRConcoprotein130.31827.735Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
252 SRIoncoprotein90.5712.975EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
253 SRSF7interactor210.45738.170RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
zf-CCHC (PF00098, IPR001878): Zinc knuckle
254 STAU1protein found in more fusions290.43762.285dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
255 STBD1interactor100CBM_20 (PF00686, IPR002044): Starch binding domain
256 STK10suppressor100DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
Pkinase (PF00069, IPR000719): Protein kinase domain
Pro_CA (PF00484, IPR001765, SM00947): Carbonic anhydrase
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
PKK (PF12474, IPR022165): Polo kinase kinase
257 STRIP1interactor31.0000ELM2 (PF01448, IPR000949): ELM2 domain
N1221 (PF07923, IPR012486): N1221-like protein
DUF3402 (PF11882, IPR021819): Domain of unknown function (DUF3402)
258 STUB1suppressor170.19269.306U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
259 STX2interactor100Syntaxin (PF00804, IPR006011, SM00503): Syntaxin
SNARE (PF05739, IPR000727, SM00397): SNARE domain
260 STX6interactor21.0000Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
SNARE (PF05739, IPR000727, SM00397): SNARE domain
261 SUMO2interactor160.29533.275Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
262 SUMO3interactor100.37820.615Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
263 SUPT5Hinteractor120.43916.830KOW (PF00467, IPR005824, SM00739): KOW motif
Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
264 SYT12interactor100C2 (PF00168, IPR000008, SM00239): C2 domain
gp12-short_mid (PF09089, IPR015173): Phage short tail fibre protein gp12, middle domain
265 SZRD1interactor100SUZ (PF12752, IPR024771): SUZ domain
SUZ-C (PF12901, IPR024642): SUZ-C motif
T3SSipB (PF16535, IPR032391): Type III cell invasion protein SipB
266 TAGLNsuppressor190.51525.506Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
267 TAGLN2protein found in more fusions450.281342.552Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
268 TAGLN3interactor160.59216.891Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
269 TALDO1interactor130.57710.857TAL_FSA (PF00923, IPR001585): Transaldolase/Fructose-6-phosphate aldolase
270 TERToncoprotein80.4296.355RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase)
Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain
271 THOC7interactor21.0000EcoEI_R_C (PF08463, IPR013670): EcoEI R protein C-terminal
THOC7 (PF05615, IPR008501): Tho complex subunit 7
UPF0193 (PF05250, IPR007914): Uncharacterised protein family (UPF0193)
272 THRAsuppressor60.6000.492C1_2 (PF03107, IPR004146): C1 domain
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
273 TK1oncoprotein90.32112.819TK (PF00265, IPR001267, SM00203): Thymidine kinase
274 TKTprotein found in more fusions550.282454.554Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
Transketolase_N (PF00456, IPR005474): Transketolase, thiamine diphosphate binding domain
275 TMEM25interactor100C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
DUF4674 (PF15719, IPR029779): Domain of unknown function (DUF4674)
276 TNPO3interactor40.6671.667HEAT (PF02985, IPR000357): HEAT repeat
IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD)
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
277 TNS3interactor100PTB (PF08416, IPR013625): Phosphotyrosine-binding domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
278 TOMM40Linteractor100Porin_3 (PF01459, IPR027246): Eukaryotic porin
279 TP53BP1suppressor160.34240.56053-BP1_Tudor (PF09038, IPR015125): Tumour suppressor p53-binding protein-1 Tudor
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
DUF4772 (PF15997, IPR031940): Domain of unknown function (DUF4772)
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
280 TPI1interactor280.42265.993TIM (PF00121, IPR000652): Triosephosphate isomerase
281 TRAPPC2interactor200Sedlin_N (PF04628, IPR006722): Sedlin, N-terminal conserved region
282 TXLNGinteractor30.6670.286FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
Taxilin (PF09728, IPR026183): Myosin-like coiled-coil protein
283 TXNoncoprotein220.45941.096Thioredoxin (PF00085, IPR013766): Thioredoxin
284 TXNDC11interactor40.5003.000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
285 TXNDC16interactor40.8330.143Thioredoxin (PF00085, IPR013766): Thioredoxin
DUF4147 (PF13660, IPR025286): Domain of unknown function (DUF4147)
Thioredoxin_6 (PF13848): Thioredoxin-like domain
286 UBAP1protein found in more fusions200MerR-DNA-bind (PF09278, IPR015358): MerR, DNA binding
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
UPF0054 (PF02130, IPR002036): Uncharacterized protein family UPF0054
287 UCHL3interactor180.44934.489Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
288 UPF2interactor100.41711.509DDHD (PF02862, IPR004177, SM01127): DDHD domain
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Upf2 (PF04050, IPR007193): Up-frameshift suppressor 2
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
SUFU_C (PF12470, IPR024314): Suppressor of Fused Gli/Ci N terminal binding domain
289 VCAM1interactor440.242190.753C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
290 VHLsuppressor280.228172.871Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein
VHL_C (PF17211): VHL box domain
291 VPS26Binteractor50.6003.500Vps26 (PF03643, IPR005377): Vacuolar protein sorting-associated protein 26
292 VPS35protein found in more fusions100.3619.934FerA (PF08165, IPR012560): FerA (NUC095) domain
Vps35 (PF03635, IPR005378): Vacuolar protein sorting-associated protein 35
293 WDR1interactor240.34482.322eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
294 WDR81interactor31.0000Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain
BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
295 WWOXsuppressor220.16595.588adh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain
296 XPO7interactor50.5003.021IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
297 XRCC6oncoprotein400.246266.642Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain
298 XRN2interactor170.40427.507XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus
299 YAP1suppressor90.27821.233Bindin (PF02084, IPR000775): Bindin
WW (PF00397, IPR001202, SM00456): WW domain
GspL_C (PF12693, IPR025691): GspL periplasmic domain
FAM181 (PF15238, IPR029359): FAM181
300 YARSinteractor70.6670.397tRNA-synt_1b (PF00579, IPR002305): tRNA synthetases class I (W and Y)
tRNA_bind (PF01588, IPR002547): Putative tRNA binding domain
301 YWHAQinteractor380.340202.70314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
302 YWHAZprotein found in more fusions400.294237.15714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
303 ZNFX1interactor21.0000zf-NF-X1 (PF01422, IPR000967, SM00438): NF-X1 type zinc finger
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 COL4A2parental proteinC4 (PF01413, IPR001442, SM00111): C-terminal tandem repeated domain in type 4 procollagen
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
2 ENO1parental proteinEnolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
3 SNORA6interactorNA

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