1 |
AV702413 | chimera | 27 | 0.085 | 570.452 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF3516 (PF12029, IPR021904): Domain of unknown function (DUF3516) |
2 |
ALYREF | interactor | 6 | 0.800 | 0.786 | FYTT (PF07078, IPR009782): Forty-two-three protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
3 |
CBS | protein found in more fusions | 3 | 1.000 | 0 | CBS (PF00571, IPR000644, SM00116): CBS domain DUF1414 (PF07208, IPR009857): Protein of unknown function (DUF1414) PALP (PF00291, IPR001926): Pyridoxal-phosphate dependent enzyme |
4 |
CDK11A | oncoprotein | 1 | 0 | 0 | DDHD (PF02862, IPR004177, SM01127): DDHD domain eIF_4EBP (PF05456, IPR008606): Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Pkinase (PF00069, IPR000719): Protein kinase domain RIO1 (PF01163, IPR018934): RIO1 family DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355) DHHW (PF14286, IPR025945): DHHW protein DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) |
5 |
CDK9 | protein found in more fusions | 2 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
6 |
CDKL5 | interactor | 2 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
7 |
EGFR | oncoprotein | 5 | 0.833 | 0.500 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
8 |
EXOSC10 | interactor | 5 | 0.800 | 0.786 | DNA_pol_A_exo1 (PF01612, IPR002562, SM00474): 3'-5' exonuclease HRDC (PF00570, IPR002121, SM00341): HRDC domain PMC2NT (PF08066, IPR012588): PMC2NT (NUC016) domain Sec62 (PF03839, IPR004728): Translocation protein Sec62 |
9 |
FBXW4 | oncoprotein | 1 | 0 | 0 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat F-box-like (PF12937, IPR001810): F-box-like F-box_4 (PF15966, IPR001810): F-box |
10 |
FERMT1 | oncoprotein | 2 | 1.000 | 0 | FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain |
11 |
GALNT13 | interactor | 1 | 0 | 0 | Glyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2 Ricin_B_lectin (PF00652, IPR000772, SM00458): Ricin-type beta-trefoil lectin domain |
12 |
ITSN1 | interactor | 3 | 1.000 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain VIT1 (PF01988, IPR008217): VIT family DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
13 |
LGR4 | interactor | 3 | 1.000 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
14 |
NDOR1 | interactor | 2 | 0 | 0 | FAD_binding_1 (PF00667, IPR003097): FAD binding domain Flavodoxin_1 (PF00258, IPR008254): Flavodoxin NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain |
15 |
NPM1 | suppressor | 9 | 0.536 | 10.119 | Nucleoplasmin (PF03066): Nucleoplasmin SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
16 |
NTRK1 | oncoprotein | 13 | 0.318 | 39.167 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
17 |
PLCG1 | oncoprotein | 4 | 0.833 | 0.500 | C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain SH2 (PF00017, IPR000980, SM00252): SH2 domain PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain PH_12 (PF16457, IPR001849): Pleckstrin homology domain |
18 |
PMPCA | interactor | 1 | 0 | 0 | Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain |
19 |
RAB4B | oncoprotein | 1 | 0 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
20 |
RAN | oncoprotein | 2 | 1.000 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
21 |
RHOU | interactor | 1 | 0 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family SLBP_RNA_bind (PF15247, IPR029344): Histone RNA hairpin-binding protein RNA-binding domain |
22 |
RPL10 | suppressor | 6 | 0.800 | 1.286 | Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e |
23 |
SIRT7 | interactor | 7 | 0.619 | 4.167 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
24 |
SNRPB | interactor | 1 | 0 | 0 | LSM (PF01423, IPR001163): LSM domain |
25 |
TSSK2 | interactor | 2 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
26 |
TTC37 | interactor | 8 | 0.464 | 13.452 | DUF982 (PF06169, IPR010385): Protein of unknown function (DUF982) Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_3 (PF07720, IPR011716): Tetratricopeptide repeat Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1 Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_15 (PF13429): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat Retrotran_gag_2 (PF14223): gag-polypeptide of LTR copia-type TPR_19 (PF14559): Tetratricopeptide repeat |
27 |
WDR1 | interactor | 2 | 1.000 | 0 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
28 |
XRN1 | interactor | 5 | 0.800 | 0.786 | XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus |