1 |
AL121228 | chimera | 173 | 0.021 | 26905.318 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
2 |
AATF | oncoprotein | 5 | 0.400 | 4.733 | DARPP-32 (PF05395, IPR008466): Protein phosphatase inhibitor 1/DARPP-32 RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TRAUB (PF08164, IPR012617): Apoptosis-antagonizing transcription factor, C-terminal Vif (PF00559, IPR000475): Retroviral Vif (Viral infectivity) protein AATF-Che1 (PF13339, IPR025160): Apoptosis antagonizing transcription factor |
3 |
ABL1 | oncoprotein | 13 | 0.621 | 12.225 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2 |
4 |
ABL2 | oncoprotein | 5 | 0.667 | 1.500 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding SH3_1 (PF00018, IPR001452, SM00326): SH3 domain NHS (PF15273, IPR024845): NHS-like |
5 |
ACVR1B | oncoprotein | 7 | 0.667 | 4.067 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
6 |
ACY3 | interactor | 2 | 0 | 0 | AstE_AspA (PF04952, IPR007036): Succinylglutamate desuccinylase / Aspartoacylase family |
7 |
ADAP2 | interactor | 2 | 1.000 | 0 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf PH (PF00169, IPR001849, SM00233): PH domain |
8 |
AICDA | interactor | 5 | 0.500 | 1.567 | APOBEC_N (PF08210, IPR013158): APOBEC-like N-terminal domain |
9 |
AKT3 | oncoprotein | 1 | 0 | 0 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
10 |
AMOT | oncoprotein | 6 | 0.700 | 2.667 | FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP) Gastrin (PF00918, IPR001651, SM00029): Gastrin/cholecystokinin family DUF2162 (PF09930, IPR017199): Predicted transporter (DUF2162) Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
11 |
AMOTL1 | interactor | 3 | 0.667 | 0.667 | NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein Presenilin (PF01080, IPR001108): Presenilin Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain |
12 |
APBB1 | interactor | 4 | 0.667 | 1.000 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) WW (PF00397, IPR001202, SM00456): WW domain RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID) |
13 |
APEX2 | interactor | 2 | 1.000 | 0 | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family zf-GRF (PF06839, IPR010666): GRF zinc finger |
14 |
ARHGDIA | interactor | 4 | 0.667 | 0.200 | Rho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor |
15 |
ARRDC1 | interactor | 3 | 0.667 | 1.000 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
16 |
ARRDC3 | interactor | 2 | 1.000 | 0 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
17 |
ARRDC4 | interactor | 1 | 0 | 0 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
18 |
ATP1B1 | interactor | 4 | 0.833 | 0.200 | Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain |
19 |
AURKC | interactor | 1 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
20 |
BBX | interactor | 2 | 1.000 | 0 | DUF2028 (PF09667, IPR019102): Domain of unknown function (DUF2028) HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box |
21 |
BMPR1A | suppressor | 4 | 1.000 | 0 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
22 |
BRAF | oncoprotein | 10 | 0.806 | 2.848 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
23 |
C7orf50 | interactor | 2 | 1.000 | 0 | DUF2373 (PF10180, IPR019327): Uncharacterised conserved protein (DUF2373) |
24 |
CACNB1 | interactor | 1 | 0 | 0 | Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase SH3_1 (PF00018, IPR001452, SM00326): SH3 domain VGCC_beta4Aa_N (PF12052, IPR000584): Voltage gated calcium channel subunit beta domain 4Aa N terminal |
25 |
CAMK1D | interactor | 2 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Tyrosinase (PF00264, IPR002227): Common central domain of tyrosinase |
26 |
CAV3 | interactor | 2 | 1.000 | 0 | Caveolin (PF01146, IPR001612): Caveolin |
27 |
CCDC8 | interactor | 12 | 0.455 | 16.529 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
28 |
CDC34 | oncoprotein | 4 | 0.667 | 0.400 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
29 |
CDK3 | interactor | 2 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
30 |
CDK5 | oncoprotein | 5 | 0.500 | 2.500 | Pkinase (PF00069, IPR000719): Protein kinase domain |
31 |
CLIC2 | interactor | 1 | 0 | 0 | MKT1_C (PF12246, IPR022039): Temperature dependent protein affecting M2 dsRNA replication GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain |
32 |
CUEDC1 | oncoprotein | 6 | 0.333 | 10.000 | CUE (PF02845, IPR003892, SM00546): CUE domain |
33 |
CYBRD1 | interactor | 1 | 0 | 0 | Cytochrom_B561 (PF03188, IPR004877): Eukaryotic cytochrome b561 Phage_holin_3_6 (PF07332, IPR009937): Putative Actinobacterial Holin-X, holin superfamily III |
34 |
CYP26B1 | interactor | 2 | 1.000 | 0 | p450 (PF00067, IPR001128): Cytochrome P450 |
35 |
DAPK3 | suppressor | 4 | 0.667 | 1.000 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pkinase (PF00069, IPR000719): Protein kinase domain PspA_IM30 (PF04012, IPR007157): PspA/IM30 family |
36 |
DAZAP2 | protein found in more fusions | 9 | 0.357 | 13.333 | DAZAP2 (PF11029, IPR022730): DAZ associated protein 2 (DAZAP2) |
37 |
DDX54 | interactor | 2 | 1.000 | 0 | DBP10CT (PF08147, IPR012541, SM01123): DBP10CT (NUC160) domain DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
38 |
DECR2 | interactor | 2 | 1.000 | 0 | adh_short_C2 (PF13561): Enoyl-(Acyl carrier protein) reductase |
39 |
DMTN | interactor | 5 | 0.600 | 1.952 | VHP (PF02209, IPR003128, SM00153): Villin headpiece domain AbLIM_anchor (PF16182, IPR032402): Putative adherens-junction anchoring region of AbLIM |
40 |
DYRK3 | interactor | 1 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
41 |
EFEMP2 | interactor | 2 | 1.000 | 0 | EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Adipogenin (PF15202, IPR027938): Adipogenin |
42 |
ELAVL1 | oncoprotein | 40 | 0.090 | 626.890 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
43 |
FAM189A2 | interactor | 6 | 0.533 | 7.000 | CD20 (PF04103, IPR007237): CD20-like family |
44 |
FAM189B | interactor | 2 | 1.000 | 0 | CD20 (PF04103, IPR007237): CD20-like family TMEM252 (PF15664, IPR031363): Transmembrane protein 252 family |
45 |
FBXL15 | interactor | 1 | 0 | 0 | LRV (PF01816, IPR004830): Leucine rich repeat variant F-box (PF00646, IPR001810, SM00256): F-box domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
46 |
FGF12 | oncoprotein | 1 | 0 | 0 | FGF (PF00167, IPR002209, SM00442): Fibroblast growth factor |
47 |
FKBP3 | interactor | 3 | 0.667 | 0.667 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase |
48 |
GORAB | suppressor | 1 | 0 | 0 | Transcrip_act (PF04949, IPR007033): Transcriptional activator Histone_HNS (PF00816, IPR001801): H-NS histone family MIT_C (PF16565, IPR032341): Phospholipase D-like domain at C-terminus of MIT |
49 |
H1F0 | interactor | 4 | 0.667 | 1.333 | OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain Hid1 (PF12722): High-temperature-induced dauer-formation protein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family |
50 |
HAX1 | interactor | 6 | 0.600 | 3.983 | Mlf1IP (PF10248, IPR019376): Myelodysplasia-myeloid leukemia factor 1-interacting protein |
51 |
HCN1 | protein found in more fusions | 2 | 0 | 0 | DUF1759 (PF03564, IPR005312): Protein of unknown function (DUF1759) Hamartin (PF04388, IPR007483): Hamartin protein Ion_trans (PF00520, IPR005821): Ion transport protein Ion_trans_N (PF08412, IPR013621): Ion transport protein N-terminal cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain |
52 |
HGS | interactor | 15 | 0.229 | 72.352 | FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate PIEZO (PF15917, IPR031805): Piezo |
53 |
IFRD2 | oncoprotein | 2 | 1.000 | 0 | IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD) IFRD_C (PF04836, IPR006921): Interferon-related protein conserved region |
54 |
IKBKB | protein found in more fusions | 2 | 0 | 0 | FliT (PF05400, IPR008622): Flagellar protein FliT Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain SlyX (PF04102, IPR007236): SlyX ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain |
55 |
KCNAB1 | interactor | 3 | 0.667 | 1.000 | Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family |
56 |
KCNAB2 | protein found in more fusions | 4 | 0.667 | 1.000 | Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family |
57 |
KCNAB3 | interactor | 2 | 1.000 | 0 | Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family |
58 |
KCNB1 | interactor | 2 | 0 | 0 | Ion_trans (PF00520, IPR005821): Ion transport protein BTB_2 (PF02214, IPR003131): BTB/POZ domain Kv2channel (PF03521, IPR003973): Kv2 voltage-gated K+ channel DUF4790 (PF16037, IPR032004): Domain of unknown function (DUF4790) |
59 |
KCNH2 | interactor | 3 | 0.667 | 1.000 | Ion_trans (PF00520, IPR005821): Ion transport protein cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain PAS_9 (PF13426, IPR000014): PAS domain |
60 |
KCNQ1 | interactor | 1 | 0 | 0 | Ion_trans (PF00520, IPR005821): Ion transport protein KCNQ_channel (PF03520, IPR013821): KCNQ voltage-gated potassium channel Sensor (PF13796, IPR025828): Putative sensor |
61 |
KIF3B | interactor | 3 | 1.000 | 0 | DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box Kinesin_assoc (PF16183, IPR032405): Kinesin-associated HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
62 |
KIFC3 | oncoprotein | 4 | 0.667 | 1.000 | Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein KxDL (PF10241, IPR019371): Uncharacterized conserved protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
63 |
LAPTM5 | oncoprotein | 2 | 1.000 | 0 | Mtp (PF03821, IPR004687): Golgi 4-transmembrane spanning transporter |
64 |
LDLRAD4 | interactor | 4 | 0.667 | 2.000 | Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A DUF2615 (PF11027, IPR020309): Protein of unknown function (DUF2615) |
65 |
LITAF | suppressor | 3 | 0.667 | 0.333 | zf-LITAF-like (PF10601, IPR006629, SM00714): LITAF-like zinc ribbon domain DUF3824 (PF12868, IPR024436): Domain of unknwon function (DUF3824) |
66 |
MAGEB1 | interactor | 1 | 0 | 0 | MAGE (PF01454, IPR002190): MAGE family MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
67 |
MAP2 | oncoprotein | 4 | 1.000 | 0 | MAP2_projctn (PF08377, IPR013588): MAP2/Tau projection domain Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat RII_binding_1 (PF10522, IPR018459): RII binding domain CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated |
68 |
MAP3K2 | protein found in more fusions | 8 | 0.762 | 2.082 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain |
69 |
MAP3K3 | oncoprotein | 7 | 0.533 | 5.071 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain |
70 |
MAP3K5 | oncoprotein | 5 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071) |
71 |
MAPKAPK3 | interactor | 1 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
72 |
MARK2 | protein found in more fusions | 11 | 0.711 | 5.053 | DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702) KA1 (PF02149, IPR001772): Kinase associated domain 1 Pkinase (PF00069, IPR000719): Protein kinase domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain |
73 |
MED28 | interactor | 5 | 0.500 | 2.000 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain Med28 (PF11594, IPR021640): Mediator complex subunit 28 |
74 |
MERTK | oncoprotein | 3 | 1.000 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_3 (PF13927): Immunoglobulin domain |
75 |
MINK1 | interactor | 1 | 0 | 0 | CNH (PF00780, IPR001180, SM00036): CNH domain Pkinase (PF00069, IPR000719): Protein kinase domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal SOBP (PF15279, IPR026092): Sine oculis-binding protein |
76 |
MOB3A | interactor | 2 | 1.000 | 0 | Mob1_phocein (PF03637, IPR005301): Mob1/phocein family |
77 |
MOV10 | interactor | 13 | 0.256 | 48.906 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
78 |
MRPL19 | interactor | 2 | 1.000 | 0 | Ribosomal_L19 (PF01245, IPR001857): Ribosomal protein L19 EABR (PF12180, IPR022008): TSG101 and ALIX binding domain of CEP55 |
79 |
MT2A | suppressor | 1 | 0 | 0 | Metallothio (PF00131, IPR003019): Metallothionein |
80 |
NDFIP1 | interactor | 5 | 0.400 | 5.500 | DUF2370 (PF10176, IPR019325): Protein of unknown function (DUF2370) WBP-1 (PF11669, IPR021684): WW domain-binding protein 1 Comm (PF15957, IPR031878): Commissureless |
81 |
NDFIP2 | interactor | 2 | 1.000 | 0 | DUF2370 (PF10176, IPR019325): Protein of unknown function (DUF2370) |
82 |
NHP2 | interactor | 2 | 1.000 | 0 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
83 |
NOTCH1 | suppressor | 7 | 0.467 | 7.500 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
84 |
NPC2 | interactor | 1 | 0 | 0 | E1_DerP2_DerF2 (PF02221, IPR003172, SM00737): ML domain |
85 |
NR3C1 | protein found in more fusions | 11 | 0.333 | 23.889 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
86 |
NSRP1 | interactor | 1 | 0 | 0 | Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR DUF2040 (PF09745, IPR018612): Coiled-coil domain-containing protein 55 (DUF2040) Macoilin (PF09726, IPR019130): Transmembrane protein PepSY_2 (PF13670, IPR025711): Peptidase propeptide and YPEB domain |
87 |
NTRK1 | oncoprotein | 30 | 0.197 | 279.816 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
88 |
NUDT16L1 | interactor | 1 | 0 | 0 | HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat |
89 |
OCLN | interactor | 3 | 0.667 | 1.000 | MARVEL (PF01284, IPR008253): Membrane-associating domain Occludin_ELL (PF07303, IPR010844): Occludin homology domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
90 |
PBX1 | oncoprotein | 3 | 1.000 | 0 | PBC (PF03792, IPR005542): PBC domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
91 |
PRKX | interactor | 2 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
92 |
PRR16 | interactor | 1 | 0 | 0 | EzrA (PF06160, IPR010379): Septation ring formation regulator, EzrA DUF4589 (PF15252, IPR027997): Domain of unknown function (DUF4589) |
93 |
PRRG1 | interactor | 2 | 1.000 | 0 | Gla (PF00594, IPR000294, SM00069): Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain RCR (PF12273, IPR020999): Chitin synthesis regulation, resistance to Congo red TMEM252 (PF15664, IPR031363): Transmembrane protein 252 family |
94 |
PRRG3 | interactor | 2 | 1.000 | 0 | Gla (PF00594, IPR000294, SM00069): Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain SKG6 (PF08693, IPR014805): Transmembrane alpha-helix domain RCR (PF12273, IPR020999): Chitin synthesis regulation, resistance to Congo red |
95 |
PSMD4 | interactor | 6 | 0.600 | 4.567 | UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain |
96 |
PTCH1 | suppressor | 1 | 0 | 0 | Patched (PF02460, IPR003392): Patched family |
97 |
PYM1 | interactor | 3 | 0.667 | 0.400 | CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD) Mago-bind (PF09282, IPR015362): Mago binding AAA_23 (PF13476): AAA domain |
98 |
RAF1 | oncoprotein | 18 | 0.353 | 58.380 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
99 |
RANBP10 | interactor | 2 | 1.000 | 0 | LisH (PF08513, IPR013720, SM00667): LisH SPRY (PF00622, IPR003877, SM00449): SPRY domain CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain |
100 |
RASL10B | suppressor | 2 | 1.000 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
101 |
RASL11B | oncoprotein | 1 | 0 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family Transferase (PF02458, IPR003480): Transferase family |
102 |
RHOB | suppressor | 2 | 1.000 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
103 |
RNF11 | protein found in more fusions | 11 | 0.378 | 18.367 | zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger |
104 |
RNF7 | oncoprotein | 6 | 0.500 | 3.000 | zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 |
105 |
ROBO3 | interactor | 1 | 0 | 0 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain |
106 |
RPL30 | interactor | 1 | 0 | 0 | NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3 |
107 |
RPS6KB2 | interactor | 5 | 0.700 | 1.300 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
108 |
SCD | interactor | 2 | 1.000 | 0 | MerC (PF03203, IPR004891): MerC mercury resistance protein |
109 |
SCNN1A | interactor | 3 | 1.000 | 0 | ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel |
110 |
SCNN1B | oncoprotein | 7 | 0.476 | 9.833 | ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel |
111 |
SCNN1G | interactor | 2 | 1.000 | 0 | ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel |
112 |
SENP2 | interactor | 2 | 1.000 | 0 | Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain |
113 |
SERPINF1 | oncoprotein | 1 | 0 | 0 | Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor) |
114 |
SFN | suppressor | 15 | 0.462 | 25.684 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
115 |
SGK1 | oncoprotein | 11 | 0.467 | 14.127 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain PX (PF00787, IPR001683, SM00312): PX domain |
116 |
SGK2 | interactor | 1 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
117 |
SGK3 | interactor | 1 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain PX (PF00787, IPR001683, SM00312): PX domain |
118 |
SIVA1 | interactor | 2 | 1.000 | 0 | Siva (PF05458, IPR022773): Cd27 binding protein (Siva) |
119 |
SLC22A11 | interactor | 1 | 0 | 0 | Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter |
120 |
SLC22A8 | interactor | 1 | 0 | 0 | Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter |
121 |
SLC7A7 | interactor | 1 | 0 | 0 | AA_permease_2 (PF13520, IPR002293): Amino acid permease |
122 |
SLC9A3 | interactor | 1 | 0 | 0 | Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin |
123 |
SMAD2 | suppressor | 10 | 0.528 | 10.733 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
124 |
SMAD3 | oncoprotein | 12 | 0.364 | 28.000 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
125 |
SMAD6 | interactor | 6 | 0.733 | 2.667 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
126 |
SMAD7 | interactor | 9 | 0.417 | 15.667 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
127 |
SNCA | interactor | 9 | 0.286 | 15.933 | Synuclein (PF01387, IPR001058): Synuclein |
128 |
SPAG8 | interactor | 1 | 0 | 0 | Zip (PF02535, IPR003689): ZIP Zinc transporter |
129 |
SRMS | interactor | 1 | 0 | 0 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
130 |
STAC | interactor | 2 | 1.000 | 0 | SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2 |
131 |
STK40 | interactor | 1 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Kinase-like (PF14531, IPR027916): Kinase-like |
132 |
SUSD6 | interactor | 2 | 1.000 | 0 | Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) |
133 |
TAF1B | interactor | 1 | 0 | 0 | Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 |
134 |
TARBP2 | interactor | 2 | 0 | 0 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
135 |
TBC1D7 | interactor | 1 | 0 | 0 | RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain |
136 |
TCEAL2 | interactor | 1 | 0 | 0 | BEX (PF04538, IPR021156): Brain expressed X-linked like family |
137 |
TGFB1I1 | interactor | 5 | 0.600 | 2.233 | LIM (PF00412, IPR001781, SM00132): LIM domain Paxillin (PF03535): Paxillin family |
138 |
TMA16 | interactor | 2 | 1.000 | 0 | Tma16 (PF11176, IPR021346): Translation machinery-associated protein 16 |
139 |
TMEM171 | interactor | 2 | 1.000 | 0 | TMEM171 (PF15471, IPR029173): Transmembrane protein family 171 |
140 |
TMEM51 | interactor | 3 | 0.667 | 1.000 | WBP-1 (PF11669, IPR021684): WW domain-binding protein 1 TMEM51 (PF15345, IPR029265): Transmembrane protein 51 |
141 |
TMEM52B | interactor | 2 | 1.000 | 0 | LSR (PF05624, IPR008664): Lipolysis stimulated receptor (LSR) TMEM52 (PF14979): Transmembrane 52 |
142 |
TMEM55A | interactor | 1 | 0 | 0 | Tmemb_55A (PF09788, IPR019178): Transmembrane protein 55A |
143 |
TMEM92 | interactor | 3 | 0.667 | 1.000 | WBP-1 (PF11669, IPR021684): WW domain-binding protein 1 |
144 |
TNK2 | interactor | 4 | 0.667 | 1.000 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal GTPase_binding (PF09027, IPR015116): GTPase binding Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6 UBA_4 (PF14555): UBA-like domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
145 |
TOLLIP | interactor | 7 | 0.533 | 3.483 | C2 (PF00168, IPR000008, SM00239): C2 domain CUE (PF02845, IPR003892, SM00546): CUE domain |
146 |
TRIM41 | interactor | 4 | 0.667 | 1.000 | BUD22 (PF09073, IPR015158): BUD22 Fer2 (PF00111, IPR001041): 2Fe-2S iron-sulfur cluster binding domain Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family RecR (PF02132, IPR023628): RecR protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain DUF3631 (PF12307, IPR022081): Protein of unknown function (DUF3631) zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
147 |
TSC22D3 | protein found in more fusions | 7 | 0.667 | 1.806 | TSC22 (PF01166, IPR000580): TSC-22/dip/bun family |
148 |
UBAC1 | interactor | 3 | 0.667 | 0.667 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain HEAT_2 (PF13646): HEAT repeats Rad60-SLD_2 (PF13881): Ubiquitin-2 like Rad60 SUMO-like |
149 |
UBC | protein found in more fusions | 30 | 0.160 | 285.295 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
150 |
UBE2D1 | interactor | 7 | 0.600 | 4.900 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
151 |
UBE2D2 | oncoprotein | 10 | 0.389 | 17.650 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
152 |
UBE2D3 | interactor | 7 | 0.400 | 6.733 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
153 |
UBE2E3 | interactor | 4 | 1.000 | 0 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
154 |
UBE2J2 | interactor | 3 | 1.000 | 0 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
155 |
UBE2K | interactor | 4 | 0.833 | 0.500 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
156 |
UBE2L3 | interactor | 10 | 0.306 | 20.000 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
157 |
UBE2N | protein found in more fusions | 6 | 0.600 | 2.333 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
158 |
VDAC2 | interactor | 5 | 0.600 | 2.400 | Porin_3 (PF01459, IPR027246): Eukaryotic porin |
159 |
WBP1 | interactor | 1 | 0 | 0 | WBP-1 (PF11669, IPR021684): WW domain-binding protein 1 |
160 |
WBP2 | interactor | 1 | 0 | 0 | GRAM (PF02893, IPR004182, SM00568): GRAM domain Vps36_ESCRT-II (PF11605, IPR021648): Vacuolar protein sorting protein 36 Vps36 |
161 |
WNK1 | interactor | 8 | 0.762 | 1.394 | SynMuv_product (PF06047, IPR009269): Ras-induced vulval development antagonist Pkinase (PF00069, IPR000719): Protein kinase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal |
162 |
WNK3 | interactor | 1 | 0 | 0 | DP (PF08781, IPR014889, SM01138): Transcription factor DP Pkinase (PF00069, IPR000719): Protein kinase domain OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal PHtD_u1 (PF16645): Unstructured region on Pneumococcal histidine triad protein |
163 |
WNK4 | interactor | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal |
164 |
XPO1 | interactor | 23 | 0.190 | 177.116 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
165 |
YWHAB | interactor | 17 | 0.463 | 33.997 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein Virulence_fact (PF13769, IPR025989): Virulence factor |
166 |
YWHAG | protein found in more fusions | 22 | 0.429 | 69.394 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
167 |
YWHAH | protein found in more fusions | 16 | 0.581 | 19.502 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
168 |
YWHAQ | interactor | 21 | 0.357 | 89.561 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
169 |
YWHAZ | protein found in more fusions | 23 | 0.390 | 82.522 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
170 |
YY1 | protein found in more fusions | 8 | 0.429 | 9.456 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail |
171 |
ZADH2 | interactor | 2 | 1.000 | 0 | ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase |
172 |
ZAK | protein found in more fusions | 7 | 0.667 | 1.318 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) DUF3552 (PF12072, IPR022711): Domain of unknown function (DUF3552) |
173 |
ZC3HAV1L | interactor | 2 | 1.000 | 0 | FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
174 |
ZDHHC3 | oncoprotein | 2 | 1.000 | 0 | DUF898 (PF05987, IPR010295): Bacterial protein of unknown function (DUF898) EI24 (PF07264): Etoposide-induced protein 2.4 (EI24) zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase IGFBP (PF00219, IPR000867, SM00121): Insulin-like growth factor binding protein DUF3615 (PF12274, IPR022059): Protein of unknown function (DUF3615) |