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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: AK130503 is the fusion of parental proteins CGNL1, HTN3 (from a repository: Wed Feb 7 22:53:43 2018)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)5
The number (and %) of the onco-proteins4 (80.00 %)
The number (and %) of the tumor suppressors1 (20.00 %)
Total number of binary PPIs (saturation %)10 (100.00 %)
The number (and %) of affected PPIs4 (40.00 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI2.800
Assortativity coefficient-0.3536
The network average Clustering coefficient0.700
The number (and %) of a zero Clustering coefficients1 (20.00 %)
The number (and %) of a zero Betweenness Centrality4 (80.00 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: HTN3,CGNL1 All fusions
: AK130503;
Proteins found in more fusions APC (see 1 fusions); YWHAG (see 1 fusions); YWHAZ (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AK130503chimera40.5006.000Abhydrolase_4 (PF08386, IPR013595): TAP-like protein
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
2 APCsuppressor200APC_15aa (PF05972, IPR009240): APC 15 residue motif
APC_basic (PF05956, IPR009234): APC basic domain
APC_r (PF05923): APC repeat
Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EB1_binding (PF05937, IPR009232): EB-1 Binding Domain
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
SAMP (PF05924, IPR009224): SAMP Motif
Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4
Arm_APC_u3 (PF16629): Armadillo-associated region on APC
APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs
APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions
APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP
APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
3 YWHAEoncoprotein31.000014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
4 YWHAGprotein found in more fusions41.000014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
5 YWHAZprotein found in more fusions41.000014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 CGNL1parental proteinAbhydrolase_4 (PF08386, IPR013595): TAP-like protein
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
2 HSPA8oncoproteinHSP70 (PF00012, IPR013126): Hsp70 protein
3 HTN3parental proteinAJAP1_PANP_C (PF15298, IPR029198): AJAP1/PANP C-terminus

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