Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: AI880081 is the fusion of parental proteins TNF (from a repository: Fri Nov 11 23:07:42 2016)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)89
The number (and %) of the onco-proteins22 (24.72 %)
The number (and %) of the tumor suppressors13 (14.61 %)
Total number of binary PPIs (saturation %)324 (8.27 %)
The number (and %) of affected PPIs88 (27.16 %)
The number of possible different fusions15
PPI diameter2
PPI radius1
The average degree of PPI6.449
Assortativity coefficient-0.4818
The network average Clustering coefficient0.436
The number (and %) of a zero Clustering coefficients33 (37.08 %)
The number (and %) of a zero Betweenness Centrality48 (53.93 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: TNF All fusions
: AI880081;
Proteins found in more fusions OPTN (see 1 fusions); HNRNPD (see 1 fusions); TAB2 (see 1 fusions); POU2F1 (see 1 fusions); RIPK1 (see 1 fusions); LYN (see 1 fusions); HSPB1 (see 3 fusions); MAP3K7 (see 7 fusions); IKBKB (see 2 fusions); FYN (see 1 fusions); CLU (see 5 fusions); B4GALT1 (see 2 fusions); LAMP2 (see 1 fusions); TNFRSF1A (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AI880081chimera880.0526452.267RseA_C (PF03873, IPR005573): Anti sigma-E protein RseA, C-terminal domain
TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
2 ABCB6interactor100ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
MTABC_N (PF16185, IPR032410): Mitochondrial ABC-transporter N-terminal five TM region
3 ACP2interactor100His_Phos_2 (PF00328, IPR000560): Histidine phosphatase superfamily (branch 2)
4 AGO2interactor40.8330.400ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Piwi (PF02171, IPR003165, SM00950): Piwi domain
ArgoN (PF16486, IPR032474): N-terminal domain of argonaute
ArgoMid (PF16487, IPR032473): Mid domain of argonaute
ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain
5 B4GALT1protein found in more fusions31.0000Glyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase
Glyco_transf_7N (PF13733, IPR027995): N-terminal region of glycosyl transferase group 7
6 B4GALT5oncoprotein21.0000Glyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase
Glyco_transf_7N (PF13733, IPR027995): N-terminal region of glycosyl transferase group 7
7 BDH1interactor100adh_short (PF00106, IPR002198): short chain dehydrogenase
DUF1776 (PF08643, IPR013952): Fungal family of unknown function (DUF1776)
8 BGNoncoprotein21.0000LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
9 BIRC2oncoprotein100.7782.986BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
10 BTRConcoprotein130.45521.686WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
11 CAPNS1interactor21.0000EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
12 CASP8suppressor130.6679.457DED (PF01335, IPR001875, SM00031): Death effector domain
Peptidase_C14 (PF00656, IPR011600): Caspase domain
13 CAV1suppressor80.6436.186Caveolin (PF01146, IPR001612): Caveolin
14 CDYLinteractor21.0000Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
ECH_2 (PF16113, IPR032259): Enoyl-CoA hydratase/isomerase
15 CELSR2interactor1007tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family)
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
GPS (PF01825, IPR000203, SM00303): GPCR proteolysis site, GPS, motif
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
Cadherin_3 (PF16184): Cadherin-like
GAIN (PF16489, IPR032471): GPCR-Autoproteolysis INducing (GAIN) domain
16 CHUKsuppressor210.42666.256Pkinase (PF00069, IPR000719): Protein kinase domain
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
17 CLUsuppressor51.0000Clusterin (PF01093, IPR000753): Clusterin
18 CPDinteractor21.0000Peptidase_M14 (PF00246, IPR000834, SM00631): Zinc carboxypeptidase
CarboxypepD_reg (PF13620): Carboxypeptidase regulatory-like domain
19 CYLDsuppressor100.6895.244CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-HIT (PF04438, IPR007529): HIT zinc finger
CYLD_phos_site (PF16607): Phosphorylation region of CYLD, unstructured
20 DAG1interactor40.6671.167DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1)
21 DCNsuppressor100LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
22 DDX19Binteractor21.0000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
23 ELAVL1oncoprotein190.203109.752RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
24 FADDsuppressor100.7335.090Death (PF00531, IPR000488, SM00005): Death domain
DED (PF01335, IPR001875, SM00031): Death effector domain
Hpt (PF01627, IPR008207, SM00073): Hpt domain
25 FASsuppressor110.51118.300Death (PF00531, IPR000488, SM00005): Death domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
Stn1_C (PF12659, IPR024263): Telomere capping C-terminal wHTH
26 FBXW11interactor70.7331.586WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
27 FLT4interactor21.0000I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
28 FREM2interactor100Calx-beta (PF03160, IPR003644, SM00237): Calx-beta domain
Cadherin_3 (PF16184): Cadherin-like
29 FYNoncoprotein70.6673.067Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
30 GKinteractor100FGGY_C (PF02782, IPR018485): FGGY family of carbohydrate kinases, C-terminal domain
FGGY_N (PF00370, IPR018484): FGGY family of carbohydrate kinases, N-terminal domain
31 GLSinteractor100Glutaminase (PF04960, IPR015868): Glutaminase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
32 GUF1interactor100EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
LepA_C (PF06421, IPR013842): GTP-binding protein LepA C-terminus
SRPRB (PF09439, IPR019009): Signal recognition particle receptor beta subunit
RF3_C (PF16658, IPR032090): Class II release factor RF3, C-terminal domain
33 HNRNPA1interactor100.50011.267RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
34 HNRNPDoncoprotein90.39313.286CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
35 HS6ST2interactor100Sulfotransfer_2 (PF03567, IPR005331): Sulfotransferase family
Clr2 (PF10383, IPR018839): Transcription-silencing protein Clr2
36 HSPA12Ainteractor100HSP70 (PF00012, IPR013126): Hsp70 protein
37 HSPA13interactor100HSP70 (PF00012, IPR013126): Hsp70 protein
38 HSPB1oncoprotein100.50010.319HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
39 HSPB2interactor50.5002.667Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
40 ICOSinteractor200V-set_2 (PF15910, IPR013106): ICOS V-set domain
41 IKBKBprotein found in more fusions160.58118.151FliT (PF05400, IPR008622): Flagellar protein FliT
Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
42 IKBKGinteractor260.337136.191CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
43 INTS5interactor100INTS5_N (PF14837, IPR029445): Integrator complex subunit 5 N-terminus
INTS5_C (PF14838, IPR029444): Integrator complex subunit 5 C-terminus
44 ITIH2interactor100ITI_HC_C (PF06668, IPR010600): Inter-alpha-trypsin inhibitor heavy chain C-terminus
VIT (PF08487, IPR013694, SM00609): Vault protein inter-alpha-trypsin domain
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
DUF4561 (PF15120, IPR027818): Domain of unknown function (DUF4561)
45 LAMP2protein found in more fusions41.0000Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
46 LNPEPoncoprotein100Peptidase_M1 (PF01433, IPR014782): Peptidase family M1
ERAP1_C (PF11838, IPR024571): ERAP1-like C-terminal domain
Dynactin (PF12455, IPR022157): Dynein associated protein
47 LYNoncoprotein50.6671.286Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
48 MAP2K2interactor200Pkinase (PF00069, IPR000719): Protein kinase domain
CAMSAP_CC1 (PF17095, IPR031372): Spectrin-binding region of Ca2+-Calmodulin
49 MAP3K7oncoprotein140.61512.505Mnd1 (PF03962, IPR005647): Mnd1 family
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
50 MTX3interactor100Tom37 (PF10568, IPR019564): Outer mitochondrial membrane transport complex protein
GST_C_6 (PF17171): Glutathione S-transferase, C-terminal domain
51 NCLNinteractor100Peptidase_M28 (PF04389, IPR007484): Peptidase family M28
52 NCR3LG1interactor100Gag_MA (PF01140, IPR000840): Matrix protein (MA), p15
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
53 NEK7interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
54 NEO1interactor21.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Neogenin_C (PF06583, IPR010560): Neogenin C-terminus
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
55 NFKBIAoncoprotein110.49116.319Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
56 NRP1interactor21.0000CUB (PF00431, IPR000859, SM00042): CUB domain
MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
DUF3481 (PF11980, IPR022579): C-terminal domain of neuropilin glycoprotein
57 OPTNprotein found in more fusions100.44412.633ARD (PF03079, IPR004313): ARD/ARD' family
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
58 OTULINinteractor50.7001.467Peptidase_C101 (PF16218, IPR023235): Peptidase family C101
59 PCDH7interactor100Cadherin_2 (PF08266, IPR013164): Cadherin-like
Protocadherin (PF08374, IPR013585): Protocadherin
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
Cadherin_3 (PF16184): Cadherin-like
60 PLXNA2interactor100IncA (PF04156, IPR007285): IncA protein
Plexin_cytopl (PF08337, IPR013548): Plexin cytoplasmic RasGAP domain
PSI (PF01437, IPR002165, SM00423): Plexin repeat
Sema (PF01403, IPR001627, SM00630): Sema domain
TIG (PF01833, IPR002909): IPT/TIG domain
61 POU2F1protein found in more fusions200Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597)
62 PSMD9interactor41.0000Remorin_C (PF03763, IPR005516): Remorin, C-terminal region
DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046)
PDZ_2 (PF13180, IPR001478): PDZ domain
63 PTPRSinteractor100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
Ig_3 (PF13927): Immunoglobulin domain
64 RALBP1interactor50.7001.267DDHD (PF02862, IPR004177, SM01127): DDHD domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SlyX (PF04102, IPR007236): SlyX
Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505)
Nod1 (PF17114, IPR032634): Gef2-related medial cortical node protein Nod1
65 RBCK1interactor100.6675.696GAGA (PF09237, IPR015318): GAGA factor
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
66 RC3H1interactor100PaaA_PaaC (PF05138, IPR007814): Phenylacetic acid catabolic protein
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
67 RIPK1protein found in more fusions200.52035.867Death (PF00531, IPR000488, SM00005): Death domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RHIM (PF12721, IPR025735): RIP homotypic interaction motif
68 RNF31interactor120.7097.160Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
PUB (PF09409, IPR018997): PUB domain
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
HOIP-UBA (PF16678, IPR032065): UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase
69 RNF8suppressor31.0000FHA (PF00498, IPR000253, SM00240): FHA domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665)
70 SEC61A1interactor100DUF1430 (PF07242, IPR006541): Protein of unknown function (DUF1430)
SecY (PF00344, IPR002208): SecY translocase
Plug_translocon (PF10559, IPR019561): Plug domain of Sec61p
71 SEMA4Cinteractor100DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
PSI (PF01437, IPR002165, SM00423): Plexin repeat
Sema (PF01403, IPR001627, SM00630): Sema domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
72 SFXN5interactor21.0000Mtc (PF03820, IPR004686): Tricarboxylate carrier
73 SHARPINinteractor110.6676.317DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518)
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Sharpin_PH (PF16764, IPR031912): Sharpin PH domain
74 TAB1interactor70.8570.983PP2C (PF00481, IPR001932): Protein phosphatase 2C
75 TAB2oncoprotein100.8331.976CUE (PF02845, IPR003892, SM00546): CUE domain
DivIC (PF04977, IPR007060): Septum formation initiator
Mnd1 (PF03962, IPR005647): Mnd1 family
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
76 TAMM41interactor200Mmp37 (PF09139, IPR015222): Mitochondrial matrix Mmp37
77 TBK1interactor110.48913.269DUF713 (PF05218, IPR007883): Protein of unknown function (DUF713)
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Pkinase (PF00069, IPR000719): Protein kinase domain
78 TM2D3interactor100TM2 (PF05154, IPR007829): TM2 domain
79 TMEM259interactor100Membralin (PF09746, IPR019144): Tumour-associated protein
80 TNFAIP3suppressor180.49335.858OTU (PF02338, IPR003323): OTU-like cysteine protease
zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger
Thioredoxin_3 (PF13192, IPR012336): Thioredoxin domain
81 TNFRSF1Aoncoprotein240.39192.096Death (PF00531, IPR000488, SM00005): Death domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
82 TNFRSF1Boncoprotein80.9050.733TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
83 TNFSF9suppressor100Albumin_I (PF08027, IPR012512): Albumin I chain b
TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
84 TNIP1interactor70.6672.567ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
Filament (PF00038, IPR001664): Intermediate filament protein
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201)
FlxA (PF14282, IPR025577): FlxA-like protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
85 TRADDinteractor120.6917.002Death (PF00531, IPR000488, SM00005): Death domain
TRADD_N (PF09034, IPR009095): TRADD, N-terminal domain
TPR_14 (PF13428): Tetratricopeptide repeat
86 TRAF2interactor240.38396.343MATH (PF00917, IPR002083, SM00061): MATH domain
Sina (PF03145, IPR018121): Seven in absentia protein family
SlyX (PF04102, IPR007236): SlyX
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
87 UFL1suppressor100CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone
Helicase_RecD (PF05127, IPR007807): Helicase
DUF2042 (PF09743, IPR018611): Uncharacterized conserved protein (DUF2042)
UBN_AB (PF14075, IPR026947): Ubinuclein conserved middle domain
IL31 (PF15209, IPR027987): Interleukin 31
88 YWHAQinteractor70.38110.66714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
89 ZFP36suppressor30.6670.667zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 CDC42oncoproteinRas (PF00071, IPR001806, SM00173): Ras family
2 HSP90B3PinteractorNA
3 RAB18oncoproteinRas (PF00071, IPR001806, SM00173): Ras family
4 RAB5AoncoproteinRas (PF00071, IPR001806, SM00173): Ras family
5 RAC1oncoproteinRas (PF00071, IPR001806, SM00173): Ras family
6 RHEBoncoproteinRas (PF00071, IPR001806, SM00173): Ras family
7 TNFparental proteinTNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
8 UBCinteractorubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
9 UBE2NinteractorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme

B a c k    t o    T o p ⇑