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Visible interactions: all affected independent (normal) missing nothing (blank)
Chimeric state: ordinary fusion big fusion

Visualization interactions

Powered by Cytoscape Web for: AI859563 is the fusion of parental proteins RNF11 (from a repository: Tue Dec 6 21:59:50 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)26
The number (and %) of the onco-proteins12 (46.15 %)
The number (and %) of the tumor suppressors1 (3.85 %)
Total number of binary PPIs (saturation %)60 (18.46 %)
The number (and %) of affected PPIs25 (41.67 %)
The number of possible different fusions11
PPI diameter2
PPI radius1
The average degree of PPI3.308
Assortativity coefficient-0.3559
The network average Clustering coefficient0.537
The number (and %) of a zero Clustering coefficients7 (26.92 %)
The number (and %) of a zero Betweenness Centrality15 (57.69 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: RNF11 All fusions
: AI859563;
Proteins found in more fusions APP (see 4 fusions); RIPK1 (see 1 fusions); CSNK2A1 (see 1 fusions); SMAD4 (see 2 fusions); UBE2E1 (see 2 fusions); UBE2O (see 1 fusions); UBE2D2 (see 2 fusions); UBE2E2 (see 1 fusions); UBE2N (see 1 fusions); CBLB (see 4 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AI859563chimera250.060538.000zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
2 AKT1oncoprotein50.6672.000PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
3 APPprotein found in more fusions70.4009.000APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
4 CBLBoncoprotein31.0000Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
PRIMA1 (PF16101): Proline-rich membrane anchor 1
5 CSNK2A1oncoprotein50.6672.000Pkinase (PF00069, IPR000719): Protein kinase domain
6 PSMD10interactor21.0000Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
7 RIPK1protein found in more fusions40.6671.000Death (PF00531, IPR000488, SM00005): Death domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RHIM (PF12721, IPR025735): RIP homotypic interaction motif
8 SMAD4suppressor31.0000MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
9 TNIP1interactor200ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
Filament (PF00038, IPR001664): Intermediate filament protein
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201)
FlxA (PF14282, IPR025577): FlxA-like protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
10 UBE2D1interactor31.0000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
11 UBE2D2oncoprotein40.6671.000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
12 UBE2D3interactor40.6671.000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
13 UBE2D4interactor200UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
14 UBE2E1protein found in more fusions31.0000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
15 UBE2E2protein found in more fusions31.0000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
16 UBE2E3interactor200UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
17 UBE2Nprotein found in more fusions50.5003.000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
18 UBE2Oprotein found in more fusions200BUD22 (PF09073, IPR015158): BUD22
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
19 UBE2Uinteractor100UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
efb-c (PF12199, IPR021033): Extracellular fibrinogen binding protein C terminal
TMEM154 (PF15102, IPR028064): TMEM154 protein family
20 UBE2V2interactor21.0000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
21 USP14interactor40.5003.000UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
22 USP2interactor30.6671.000UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
23 USP5interactor21.0000UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
24 USP7oncoprotein50.5003.000MATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
25 YWHAQinteractor10014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
26 ZNF350interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ANKRD13AinteractorUIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
GPCR_chapero_1 (PF11904, IPR021832): GPCR-chaperone
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)
2 AP2A1interactorAdaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
HEAT_2 (PF13646): HEAT repeats
3 AP2B1interactorAdaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain
4 AP2M1interactorAdap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
5 AP2S1interactorClat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
6 ASCC2interactorCUE (PF02845, IPR003892, SM00546): CUE domain
BLOC1S3 (PF15753, IPR017245): Biogenesis of lysosome-related organelles complex 1 subunit 3
7 AUP1interactorCUE (PF02845, IPR003892, SM00546): CUE domain
8 CALCOCO2interactorbZIP_1 (PF00170, IPR004827): bZIP transcription factor
CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
zf-C2H2_4 (PF13894): C2H2-type zinc finger
9 CCDC127interactorExonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
Metal_resist (PF13801, IPR025961): Heavy-metal resistance
10 CSNK2BinteractorCK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
11 DCUN1D1interactorCullin_binding (PF03556, IPR005176): Cullin binding
UBA_4 (PF14555): UBA-like domain
12 EPN1interactorENTH (PF01417, IPR001026, SM00273): ENTH domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
13 EPN3interactorENTH (PF01417, IPR001026, SM00273): ENTH domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
14 EPS15oncoproteinReo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
15 ERCC6oncoproteinSeryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
16 GGA1oncoproteinAlpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
GAT (PF03127, IPR004152): GAT domain
Hormone_3 (PF00159, IPR001955): Pancreatic hormone peptide
VHS (PF00790, IPR002014, SM00288): VHS domain
AP3B1_C (PF14796, IPR029390): Clathrin-adaptor complex-3 beta-1 subunit C-terminal
17 GGA2interactorAlpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
GAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain
18 GGA3interactorAlpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
GAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain
19 GTF2H1oncoproteinBSD (PF03909, IPR005607, SM00751): BSD domain
PH_TFIIH (PF08567, IPR013876): TFIIH p62 subunit, N-terminal domain
20 GTF2H4interactorTfb2 (PF03849, IPR004598): Transcription factor Tfb2
21 HGSinteractorFYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
PIEZO (PF15917, IPR031805): Piezo
22 IKBKEinteractorIncA (PF04156, IPR007285): IncA protein
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon
23 IKBKGinteractorCENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
24 ITCHinteractorC2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
25 MYO6interactorBUD22 (PF09073, IPR015158): BUD22
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Rad9 (PF04139, IPR007268): Rad9
Sec62 (PF03839, IPR004728): Translocation protein Sec62
XhlA (PF10779, IPR019715): Haemolysin XhlA
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887)
Myosin-VI_CBD (PF16521, IPR032412): Myosin VI cargo binding domain
26 NEDD4suppressorRota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
27 NEDD4LsuppressorWW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
28 OPTNinteractorARD (PF03079, IPR004313): ARD/ARD' family
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
29 PDCD6IPinteractorBRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
30 POLIinteractorIMS (PF00817, IPR001126): impB/mucB/samB family
Cdd1 (PF11731, IPR021725): Pathogenicity locus
IMS_HHH (PF11798, IPR024728): IMS family HHH motif
IMS_C (PF11799, IPR017961): impB/mucB/samB family C-terminal domain
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
31 PSMD1interactorPA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin)
PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
HEAT_2 (PF13646): HEAT repeats
32 PSMD11interactorDUF247 (PF03140, IPR004158): Plant protein of unknown function
PCI (PF01399, IPR000717, SM00088): PCI domain
AAA_16 (PF13191): AAA ATPase domain
TPR_12 (PF13424): Tetratricopeptide repeat
33 PSMD12interactorTubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
PCI (PF01399, IPR000717, SM00088): PCI domain
34 PSMD13interactorMitovir_RNA_pol (PF05919, IPR008686): Mitovirus RNA-dependent RNA polymerase
PCI (PF01399, IPR000717, SM00088): PCI domain
35 PSMD14interactorJAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
36 PSMD2oncoproteinPC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
THAP (PF05485, IPR006612, SM00980): THAP domain
HEAT_2 (PF13646): HEAT repeats
37 PSMD3interactorRpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
38 PSMD4interactorUIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
39 PSMD5interactorProteasom_PSMB (PF10508, IPR019538): Proteasome non-ATPase 26S subunit
40 PSMD6interactorRPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7
PCI (PF01399, IPR000717, SM00088): PCI domain
41 PSMD7interactorJAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
Auts2 (PF15336): Autism susceptibility gene 2 protein
Coilin_N (PF15862, IPR031722): Coilin N-terminus
42 PSMD8interactorCSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
43 PTPRCsuppressorfn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
PTP_N (PF12453, IPR024739): Protein tyrosine phosphatase N terminal
CD45 (PF12567, IPR016335): Leukocyte receptor CD45
SCIMP (PF15050, IPR028181): SCIMP protein
44 QARSinteractortRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain
tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain
tRNA_synt_1c_R1 (PF04558, IPR007639): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1
tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
45 RABGEF1interactorRho_Binding (PF08912, IPR015008): Rho Binding
VPS9 (PF02204, IPR003123, SM00167): Vacuolar sorting protein 9 (VPS9) domain
zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger
GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term
SSTK-IP (PF15836, IPR031679): SSTK-interacting protein, TSSK6-activating co-chaperone protein
46 RNF11parental proteinzf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger
47 RNF168interactorATP-synt_E (PF05680, IPR008386): ATP synthase E chain
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
48 RNF216oncoproteinDUF226 (PF02890, IPR004180): Borrelia family of unknown function DUF226
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
DUF4645 (PF15488, IPR027891): Domain of unknown function (DUF4645)
49 RPS27AinteractorDUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
50 SMURF1interactorC2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
51 SMURF2interactorC2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
52 SNRNP70interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
53 STAM2interactorGAT (PF03127, IPR004152): GAT domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
54 STAMBPinteractorUSP8_dimer (PF08969, IPR015063): USP8 dimerisation domain
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
DUF3526 (PF12040, IPR021913): Domain of unknown function (DUF3526)
55 STAT1suppressorSH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain
56 TAX1BP1interactorCALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
PolyA_pol (PF01743, IPR002646): Poly A polymerase head domain
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
zf-C2H2_4 (PF13894): C2H2-type zinc finger
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
57 TBK1interactorDUF713 (PF05218, IPR007883): Protein of unknown function (DUF713)
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Pkinase (PF00069, IPR000719): Protein kinase domain
58 TNFAIP3suppressorOTU (PF02338, IPR003323): OTU-like cysteine protease
zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger
Thioredoxin_3 (PF13192, IPR012336): Thioredoxin domain
59 TOM1L2suppressorGAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain
60 UBA52interactorRibosomal_L40e (PF01020, IPR001975): Ribosomal L40e family
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
61 UBCinteractorubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
62 UBQLN2interactorClathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
SUZ (PF12752, IPR024771): SUZ domain
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
63 UBQLN4interactorCRF (PF00473, IPR000187, SM00039): Corticotropin-releasing factor family
DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
Arm_2 (PF04826, IPR006911): Armadillo-like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
partial_CstF (PF15861, IPR031721): Partial cleavage stimulation factor domain
64 WWP1oncoproteinC2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
65 WWP2interactorWW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
66 ZFYVE16interactorFYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
DUF3480 (PF11979, IPR022557): Domain of unknown function (DUF3480)
67 ZFYVE9interactorFYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
SARA (PF11409, IPR024608): Smad anchor for receptor activation (SARA)
DUF3480 (PF11979, IPR022557): Domain of unknown function (DUF3480)

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