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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: AI538939 is the fusion of parental proteins APPBP2, SMARCA5 (from a repository: Fri Feb 9 03:30:25 2018)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)161
The number (and %) of the onco-proteins49 (30.43 %)
The number (and %) of the tumor suppressors29 (18.01 %)
Total number of binary PPIs (saturation %)1317 (10.23 %)
The number (and %) of affected PPIs160 (12.15 %)
The number of possible different fusions24
PPI diameter2
PPI radius1
The average degree of PPI15.590
Assortativity coefficient-0.2637
The network average Clustering coefficient0.479
The number (and %) of a zero Clustering coefficients14 (8.70 %)
The number (and %) of a zero Betweenness Centrality36 (22.36 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: APPBP2,SMARCA5 All fusions
: AI538939;
Proteins found in more fusions NPM1 (see 1 fusions); CUL7 (see 2 fusions); RNF168 (see 2 fusions); MYC (see 1 fusions); UBE2R2 (see 1 fusions); PRKDC (see 3 fusions); SMARCC1 (see 2 fusions); UBC (see 1 fusions); MSH2 (see 1 fusions); SS18 (see 1 fusions); RPA1 (see 1 fusions); RASSF5 (see 2 fusions); TP53 (see 3 fusions); SUZ12 (see 2 fusions); SNW1 (see 1 fusions); APP (see 4 fusions); LMNA (see 3 fusions); LUC7L2 (see 2 fusions); VCP (see 4 fusions); SFPQ (see 6 fusions); CREB1 (see 2 fusions); USF1 (see 3 fusions); CHD3 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AI538939chimera1600.08615445.535HAND (PF09110, IPR015194): HAND
SLIDE (PF09111, IPR015195): SLIDE
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DBINO (PF13892, IPR020838): DNA-binding domain
2 ABCE1interactor100.5003.282ABC_tran (PF00005, IPR003439): ABC transporter
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
AAA_29 (PF13555): P-loop containing region of AAA domain
3 AIM2suppressor100HIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
DUF2950 (PF11453, IPR021556): Protein of unknown function (DUF2950)
4 ANKRD10interactor100Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
5 APPprotein found in more fusions350.128369.754APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
6 BAZ1Ainteractor150.26747.665CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DDT (PF02791, IPR004022, SM00571): DDT domain
GBP_C (PF02841, IPR003191): Guanylate-binding protein, C-terminal domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1
WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif
7 BAZ1Binteractor200.31156.677D5_N (PF08706, IPR014818, SM00885): D5 N terminal like
DDT (PF02791, IPR004022, SM00571): DDT domain
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
PHD (PF00628, IPR019787, SM00249): PHD-finger
YL1 (PF05764, IPR008895): YL1 nuclear protein
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3635 (PF12330, IPR024604): Domain of unknown function (DUF3635)
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
FAM176 (PF14851): FAM176 family
WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1
WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif
8 BAZ2Ainteractor80.5367.266AT_hook (PF02178, IPR017956, SM00384): AT hook motif
DDHD (PF02862, IPR004177, SM01127): DDHD domain
DDT (PF02791, IPR004022, SM00571): DDT domain
MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1
WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif
9 BEND3interactor70.6002.833BEN (PF10523, IPR018379, SM01025): BEN domain
Uteroglobin (PF01099, IPR016126, SM00096): Uteroglobin family
10 BMI1oncoprotein200.40934.283zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
11 BRCA1suppressor310.35294.991BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
12 C17orf49interactor90.4447.186Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
13 CALM3interactor100EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
14 CCDC8interactor340.312118.377Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
15 CCDC85Cinteractor21.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
CCDC85 (PF10226, IPR019359): CCDC85 family
16 CCNL1interactor21.0000Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
DUF936 (PF06075, IPR010341): Plant protein of unknown function (DUF936)
17 CDC5Linteractor370.386124.017OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
18 CDK16oncoprotein60.7331.153Pkinase (PF00069, IPR000719): Protein kinase domain
19 CDK2suppressor340.292154.695Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
20 CDT1oncoprotein50.6000.937CDT1 (PF08839, IPR014939, SM01075): DNA replication factor CDT1 like
CDT1_C (PF16679, IPR032054): DNA replication factor Cdt1 C-terminal domain
21 CEBPBoncoprotein80.7621.669RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
22 CECR2interactor21.0000DDT (PF02791, IPR004022, SM00571): DDT domain
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif
23 CENPAinteractor140.48715.903Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
24 CHD3oncoprotein240.38769.884CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
FAM176 (PF14851): FAM176 family
25 CHRAC1interactor60.6002.733FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone
26 COPS2suppressor110.47312.818YozE_SAM_like (PF06855, IPR023089): YozE SAM-like fold
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2087 (PF09860, IPR018656): Uncharacterized protein conserved in bacteria (DUF2087)
PCI (PF01399, IPR000717, SM00088): PCI domain
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
27 COPS3interactor110.54511.860RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
28 COPS6interactor160.46727.272DUF320 (PF03777, IPR005528): Small secreted domain (DUF320)
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
29 CORO2Boncoprotein100DivIC (PF04977, IPR007060): Septum formation initiator
DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_4 (PF16300): Type of WD40 repeat
30 CREB1oncoprotein190.39248.360bZIP_1 (PF00170, IPR004827): bZIP transcription factor
pKID (PF02173, IPR003102): pKID domain
DUF4988 (PF16378, IPR032149): Domain of unknown function
31 CREB3interactor200bZIP_1 (PF00170, IPR004827): bZIP transcription factor
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
32 CSNK1G2interactor21.0000Pkinase (PF00069, IPR000719): Protein kinase domain
CK1gamma_C (PF12605, IPR022247): Casein kinase 1 gamma C terminal
33 CTNNB1oncoprotein180.32742.335Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
34 CUL2suppressor240.34180.146Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
35 CUL5suppressor200.38455.727Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
36 CUL7protein found in more fusions380.336132.505ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
37 DAXXoncoprotein130.42412.968Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Nop14 (PF04147, IPR007276): Nop14-like family
RF-1 (PF00472, IPR000352): RF-1 domain
Vpu (PF00558, IPR008187): Vpu protein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
38 DHRS2interactor100adh_short (PF00106, IPR002198): short chain dehydrogenase
39 DNMT1suppressor160.54316.101BAH (PF01426, IPR001025, SM00439): BAH domain
DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain
DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
40 DNMT3Bsuppressor130.57713.801DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
PWWP (PF00855, IPR000313, SM00293): PWWP domain
41 EEDsuppressor400.283209.265WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
42 EIF4A3interactor220.41442.776DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
43 FOXB1interactor80.5364.541Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
44 FOXC1suppressor100.35613.277TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
PAF (PF15715, IPR031444): PCNA-associated factor
PRIMA1 (PF16101): Proline-rich membrane anchor 1
45 FOXC2oncoprotein60.8000.472Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
46 FOXE1oncoprotein60.4672.883Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
47 FOXG1oncoprotein70.4762.460SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
SPX (PF03105, IPR004331): SPX domain
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
48 FOXJ2interactor80.5004.937SARAF (PF06682, IPR009567): SOCE-associated regulatory factor of calcium homoeostasis
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
Spt20 (PF12090, IPR021950): Spt20 family
Pro-rich (PF15240, IPR026086): Proline-rich
49 FOXJ3interactor31.0000Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
50 FOXK2interactor120.48516.063FHA (PF00498, IPR000253, SM00240): FHA domain
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
51 FOXL1oncoprotein80.5363.729Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
52 FOXM1oncoprotein21.0000EspF (PF04806, IPR006891): EspF protein repeat
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
53 FOXQ1interactor50.4001.398Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
54 FOXR1interactor31.0000Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
55 FOXS1interactor70.5243.612Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
56 HDAC1suppressor440.257323.716FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
57 HDAC2suppressor490.248422.727Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
58 HDGFinteractor180.40521.450PWWP (PF00855, IPR000313, SM00293): PWWP domain
59 HIPK4interactor21.0000Pkinase (PF00069, IPR000719): Protein kinase domain
60 HIST1H2AKinteractor21.0000Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
61 HIST1H3Ainteractor180.42635.731Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
62 HIST1H4Ainteractor220.29477.468CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
63 HIST2H2ABinteractor60.6001.050Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
64 HNRNPMinteractor250.42055.866RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
65 HNRNPRinteractor280.45554.358RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
66 HNRNPUinteractor400.326196.810CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
67 HSPA4interactor150.49513.205Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
68 IFI16suppressor160.28337.784HIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
69 IKinteractor190.49023.620Lsm_interact (PF05391, IPR008669): Lsm interaction motif
RED_C (PF07807, IPR012492): RED-like protein C-terminal region
RED_N (PF07808, IPR012916): RED-like protein N-terminal region
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
70 IKBKEinteractor51.0000IncA (PF04156, IPR007285): IncA protein
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon
71 INO80interactor50.7002.067Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
POTRA (PF07244, IPR010827): Surface antigen variable number repeat
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DBINO (PF13892, IPR020838): DNA-binding domain
FAM176 (PF14851): FAM176 family
MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
72 IPO9interactor90.5286.147IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
HEAT_EZ (PF13513): HEAT-like repeat
73 KBTBD7interactor21.0000BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_2 (PF07646, IPR011498): Kelch motif
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_4 (PF13418): Galactose oxidase, central domain
Kelch_6 (PF13964): Kelch motif
74 KLF11interactor31.0000zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
75 KLHL35interactor100BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
Kelch_6 (PF13964): Kelch motif
76 LMNAprotein found in more fusions240.45845.114Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
77 LONRF3interactor100LON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain
PGA2 (PF07543, IPR011431): Protein trafficking PGA2
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_16 (PF13432): Tetratricopeptide repeat
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
CX9C (PF16860, IPR031731): CHCH-CHCH-like Cx9C, IMS import disulfide relay-system
78 LUC7L2protein found in more fusions100.6392.965LUC7 (PF03194, IPR004882): LUC7 N_terminus
Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein
Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
79 LUZP4interactor60.6001.126Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
80 MAFoncoprotein41.0000bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
Maf_N (PF08383, IPR013592): Maf N-terminal region
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
Sporozoite_P67 (PF05642, IPR008845): Sporozoite P67 surface antigen
TraT (PF05818, IPR008874): Enterobacterial TraT complement resistance protein
Metal_resist (PF13801, IPR025961): Heavy-metal resistance
81 MAXsuppressor140.28228.228ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
SlyX (PF04102, IPR007236): SlyX
82 MBD3interactor130.53015.340DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain
83 MCM3interactor120.4557.333MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
84 MLLT3oncoprotein31.0000Peptidase_S64 (PF08192, IPR012985): Peptidase family S64
YEATS (PF03366, IPR005033): YEATS family
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
NKAP (PF15692): NF-kappa-B-activating protein
BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation
85 MSH2suppressor190.46419.077MutS_I (PF01624, IPR007695): MutS domain I
MutS_II (PF05188, IPR007860): MutS domain II
MutS_V (PF00488, IPR000432, SM00534): MutS domain V
MutS_III (PF05192, IPR007696, SM00533): MutS domain III
AAA_27 (PF13514): AAA domain
86 MYBBP1Asuppressor240.40960.175DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal
87 MYConcoprotein290.310134.270HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
88 MYO1Cinteractor140.35221.111IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
89 NCSTNinteractor140.48416.629Nicastrin (PF05450, IPR008710): Nicastrin
Ost4 (PF10215, IPR018943): Oligosaccaryltransferase
90 NFATC1oncoprotein100.46711.525RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
91 NLRP3oncoprotein21.0000NACHT (PF05729): NACHT domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
FISNA (PF14484, IPR029495): Fish-specific NACHT associated domain
92 NOTCH1suppressor160.34321.785Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
NOD (PF06816, IPR010660): NOTCH protein
NODP (PF07684, IPR011656): NOTCH protein
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Notch (PF00066, IPR000800, SM00004): LNR domain
DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
93 NPM1suppressor340.356130.055Nucleoplasmin (PF03066): Nucleoplasmin
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
94 NPRL3interactor30.6671.000NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3
95 NTRK1oncoprotein600.210660.321I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
96 OBSL1interactor370.319136.794BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
97 PCSK5interactor100P_proprotein (PF01483, IPR002884): Proprotein convertase P-domain
Peptidase_S8 (PF00082, IPR000209): Subtilase family
VSP (PF03302, IPR005127): Giardia variant-specific surface protein
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
Furin-like_2 (PF15913, IPR006212): Furin-like repeat, cysteine-rich
S8_pro-domain (PF16470, IPR032815): Peptidase S8 pro-domain
98 PHGDHinteractor190.44423.0092-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
99 POLE3interactor60.6002.450BUD22 (PF09073, IPR015158): BUD22
CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone
100 POLR1Ainteractor120.42423.386RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
101 POLR1Cinteractor70.7142.717RNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain
102 POLR3Ainteractor100.51111.527RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
103 POLR3Binteractor90.5289.725RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
104 PPP1CAsuppressor230.36077.641Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
105 PPP1R8interactor70.6191.965FHA (PF00498, IPR000253, SM00240): FHA domain
106 PRKACBinteractor21.0000Pkinase (PF00069, IPR000719): Protein kinase domain
107 PRKDCprotein found in more fusions300.34787.764FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
108 PYROXD2interactor100Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
NAD_binding_8 (PF13450): NAD(P)-binding Rossmann-like domain
109 RAD21oncoprotein220.44636.714Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein
Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
110 RASSF5suppressor200RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
111 RBBP4oncoprotein340.324166.587eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
112 RBBP7suppressor250.35096.583WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
113 RBM14suppressor250.37064.313RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
114 RBPJinteractor110.40012.401BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain
LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding
TIG (PF01833, IPR002909): IPT/TIG domain
115 RNF168protein found in more fusions31.0000ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
116 RNF2interactor460.260317.060zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
117 RNF34interactor30.6670.182Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
SAP (PF02037, IPR003034, SM00513): SAP domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
118 RPA1suppressor340.46078.750Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
119 RPA2oncoprotein290.323112.420RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
120 RPA3interactor220.47624.395Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
121 RPL10suppressor160.50015.215Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
122 RRS1interactor120.50012.039GRP (PF07172, IPR010800): Glycine rich protein family
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
RRS1 (PF04939, IPR007023): Ribosome biogenesis regulatory protein (RRS1)
123 RSF1oncoprotein40.5001.567DDT (PF02791, IPR004022, SM00571): DDT domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
PHD (PF00628, IPR019787, SM00249): PHD-finger
UPF0239 (PF06783, IPR009621): Uncharacterised protein family (UPF0239)
TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1
124 RUVBL1oncoprotein270.37575.724TIP49 (PF06068, IPR010339): TIP49 C-terminus
125 RUVBL2oncoprotein320.363105.461TIP49 (PF06068, IPR010339): TIP49 C-terminus
126 S100A9oncoprotein110.6004.990S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
127 SAP18interactor210.35757.192SAP18 (PF06487, IPR010516): Sin3 associated polypeptide p18 (SAP18)
128 SATB1oncoprotein170.25761.258CUT (PF02376, IPR003350, SM01109): CUT domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371)
ULD (PF16534, IPR032392): Ubiquitin-like oligomerisation domain of SATB
CUTL (PF16557, IPR032355): CUT1-like DNA-binding domain of SATB
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
129 SEPT2oncoprotein90.5836.074FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Septin (PF00735, IPR000038): Septin
130 SEPT7interactor90.6673.409Fez1 (PF06818): Fez1
Septin (PF00735, IPR000038): Septin
131 SFPQoncoprotein220.54817.517GRP (PF07172, IPR010800): Glycine rich protein family
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
132 SIN3Aoncoprotein250.35093.764Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
133 SKAP1interactor70.5334.567PH (PF00169, IPR001849, SM00233): PH domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
134 SLC25A23interactor100Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
135 SMARCA1interactor230.194124.552ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
HAND (PF09110, IPR015194): HAND
SLIDE (PF09111, IPR015195): SLIDE
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DBINO (PF13892, IPR020838): DNA-binding domain
136 SMARCAD1interactor220.38548.379CUE (PF02845, IPR003892, SM00546): CUE domain
Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
137 SMARCC1suppressor200.40933.888SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
138 SMARCC2interactor280.33687.699GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
139 SMC1Aoncoprotein270.32389.801SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
140 SMC3oncoprotein320.315131.579SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
141 SNW1protein found in more fusions430.311227.459SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
142 SOX2oncoprotein210.36844.461HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
143 SS18oncoprotein90.7861.433SSXT (PF05030, IPR007726): SSXT protein (N-terminal region)
Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor
144 SSX2oncoprotein61.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
145 SUZ12suppressor270.33592.201DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
146 TBL3interactor70.5711.307SdiA-regulated (PF06977, IPR009722): SdiA-regulated
Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
147 TCEB2interactor60.7331.786ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
148 TEAD2interactor80.3937.802TEA (PF01285, IPR000818, SM00426): TEA/ATTS domain family
149 TP53suppressor490.227480.190DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
150 UBCprotein found in more fusions320.363143.128ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
151 UBE2R2protein found in more fusions31.0000NOA36 (PF06524, IPR010531): NOA36 protein
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
152 UBTFinteractor130.44912.971Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein
HMG_box_2 (PF09011, IPR009071): HMG-box domain
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
DUF4473 (PF14747, IPR027913): Domain of unknown function (DUF4473)
HMG_box_5 (PF14887, IPR029215): HMG (high mobility group) box 5
153 USF1oncoprotein90.4295.016HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
154 VCPprotein found in more fusions230.42944.972AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
155 WASoncoprotein100CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
WH2 (PF02205, IPR003124, SM00246): WH2 motif
PRIMA1 (PF16101): Proline-rich membrane anchor 1
156 WDR24interactor21.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type
157 XRCC4interactor50.6670.583XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4
158 XRCC5suppressor320.243159.432Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
159 ZC3H10suppressor200bZIP_1 (PF00170, IPR004827): bZIP transcription factor
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
160 ZCCHC12interactor21.0000PNMA (PF14893, IPR026523): PNMA
zf-C2H2_10 (PF16588, IPR001878): C2H2 zinc-finger
161 ZNF747interactor21.0000Zn-ribbon_8 (PF09723, IPR013429, SM00834): Zinc ribbon domain
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 AHCYinteractorAdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
2 AK3interactorADK (PF00406, IPR000850): Adenylate kinase
3 AP4S1interactorClat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
4 APPBP2parental proteinTPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
5 ARMCX5interactorArm_2 (PF04826, IPR006911): Armadillo-like
6 C1QTNF2interactorC1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
7 C1orf50interactorDUF2452 (PF10504, IPR019534): Protein of unknown function (DUF2452)
8 C6orf226interactorDUF4267 (PF14087, IPR025363): Domain of unknown function (DUF4267)
9 CHMP5interactorSnf7 (PF03357, IPR005024): Snf7
10 CLCN1interactorCBS (PF00571, IPR000644, SM00116): CBS domain
Voltage_CLC (PF00654, IPR001807): Voltage gated chloride channel
11 CNTFRinteractorfn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ig_3 (PF13927): Immunoglobulin domain
CBP_CCPA (PF17040, IPR031480): Cellulose-complementing protein A
12 COL24A1interactorCOLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
13 CTC1interactorCTC1 (PF15489, IPR029156): CST, telomere maintenance, complex subunit CTC1
14 DCDinteractorDermcidin (PF15291, IPR028130): Dermcidin, antibiotic peptide
15 DPEP1interactorPeptidase_M19 (PF01244, IPR008257): Membrane dipeptidase (Peptidase family M19)
16 EID3interactorNse4_C (PF08743, IPR014854): Nse4 C-terminal
Nse4-Nse3_bdg (PF15412, IPR029225): Binding domain of Nse4/EID3 to Nse3-MAGE
17 ERO1AinteractorERO1 (PF04137, IPR007266): Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
18 FAM19A4interactorTAFA (PF12020, IPR020350): TAFA family
19 FAM92A1interactorFAM92 (PF06730, IPR009602): FAM92 protein
20 FSTL1interactorFOLN (PF09289, IPR015369, SM00274): Follistatin/Osteonectin-like EGF domain
Pacifastin_I (PF05375, IPR008037): Pacifastin inhibitor (LCMII)
Kazal_2 (PF07648, IPR002350, SM00280): Kazal-type serine protease inhibitor domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
21 FXYD7interactorATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family
22 GALNT3interactorGlyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase
Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
SecY (PF00344, IPR002208): SecY translocase
Ricin_B_lectin (PF00652, IPR000772, SM00458): Ricin-type beta-trefoil lectin domain
23 GCSAMinteractorDUF4513 (PF14983, IPR027965): Domain of unknown function (DUF4513)
HGAL (PF15666, IPR031364): Germinal center-associated lymphoma
24 GP9interactorInvolucrin2 (PF06994, IPR009733): Involucrin
25 GSTP1suppressorGST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
26 KIF6interactorDUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
PolyA_pol (PF01743, IPR002646): Poly A polymerase head domain
UAF_Rrn10 (PF05234, IPR022793): UAF complex subunit Rrn10
DUF2203 (PF09969, IPR018699): Uncharacterized conserved protein (DUF2203)
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Microtub_bd (PF16796, IPR031852): Microtubule binding
27 LANCL2interactorGlyco_hydro_127 (PF07944, IPR012878): Beta-L-arabinofuranosidase, GH127
LANC_like (PF05147, IPR007822): Lanthionine synthetase C-like protein
28 MFSD3interactorMFS_1 (PF07690, IPR011701): Major Facilitator Superfamily
29 MGC34796interactorNA
30 MUL1interactorDUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
DUF3040 (PF11239, IPR021401): Protein of unknown function (DUF3040)
GIDE (PF12483, IPR022170): E3 Ubiquitin ligase
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
31 NFYAinteractorCBFB_NFYA (PF02045, IPR001289): CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B
MSP1_C (PF07462, IPR010901): Merozoite surface protein 1 (MSP1) C-terminus
FixG_C (PF11614, IPR032879): IG-like fold at C-terminal of FixG, putative oxidoreductase
DUF4237 (PF14021, IPR025331): Protein of unknown function (DUF4237)
32 PI4KAP2interactorNA
33 PRKAA2suppressorPkinase (PF00069, IPR000719): Protein kinase domain
AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
34 RASSF8suppressorETC_C1_NDUFA5 (PF04716, IPR006806): ETC complex I subunit conserved region
FliD_C (PF07195, IPR010809): Flagellar hook-associated protein 2 C-terminus
PEARLI-4 (PF05278, IPR007942): Arabidopsis phospholipase-like protein (PEARLI 4)
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
35 RNF128interactorCcmD (PF04995, IPR007078): Heme exporter protein D (CcmD)
PA (PF02225, IPR003137): PA domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
36 SCARNA22interactorNA
37 SCFD1interactorSec1 (PF00995, IPR001619): Sec1 family
38 SELENOIinteractorCDP-OH_P_transf (PF01066, IPR000462): CDP-alcohol phosphatidyltransferase
DUF1700 (PF08006, IPR012963): Protein of unknown function (DUF1700)
39 SELENOVinteractorDUF963 (PF06131, IPR009306): Schizosaccharomyces pombe repeat of unknown function (DUF963)
Rdx (PF10262, IPR011893): Rdx family
40 SLAIN2interactorbZIP_1 (PF00170, IPR004827): bZIP transcription factor
SLAIN (PF15301, IPR026179): SLAIN motif-containing family
41 SLC22A6interactorSugar_tr (PF00083, IPR005828): Sugar (and other) transporter
42 SMARCA5parental proteinHAND (PF09110, IPR015194): HAND
SLIDE (PF09111, IPR015195): SLIDE
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DBINO (PF13892, IPR020838): DNA-binding domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
43 SNX5oncoproteinPX (PF00787, IPR001683, SM00312): PX domain
Vps5 (PF09325, IPR015404): Vps5 C terminal like
44 ST8SIA5interactorGlyco_transf_29 (PF00777, IPR001675): Glycosyltransferase family 29 (sialyltransferase)
45 SYNRGinteractorEF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
46 SYT11interactorC2 (PF00168, IPR000008, SM00239): C2 domain
CoatB (PF10389, IPR008020): Bacteriophage coat protein B
47 TAF11interactorCENP-X (PF09415, IPR018552): CENP-S associating Centromere protein X
TAFII28 (PF04719, IPR006809): hTAFII28-like protein conserved region
48 TCEB1oncoproteinSkp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
49 TCF25interactorTcf25 (PF04910, IPR006994): Transcriptional repressor TCF25
DUF4604 (PF15377, IPR027911): Domain of unknown function (DUF4604)
50 UGGT2interactorGlyco_transf_8 (PF01501, IPR002495): Glycosyl transferase family 8
UDP-g_GGTase (PF06427, IPR009448): UDP-glucose:Glycoprotein Glucosyltransferase
51 WNT5Binteractorwnt (PF00110, IPR005817, SM00097): wnt family

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