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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: AI470274 is the fusion of parental proteins FARP2, HSPB1 (from a repository: Thu Dec 8 08:36:52 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)365
The number (and %) of the onco-proteins96 (26.30 %)
The number (and %) of the tumor suppressors30 (8.22 %)
Total number of binary PPIs (saturation %)2815 (4.24 %)
The number (and %) of affected PPIs364 (12.93 %)
The number of possible different fusions61
PPI diameter2
PPI radius1
The average degree of PPI14.734
Assortativity coefficient-0.2924
The network average Clustering coefficient0.463
The number (and %) of a zero Clustering coefficients48 (13.15 %)
The number (and %) of a zero Betweenness Centrality95 (26.03 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: HSPB1,FARP2 All fusions
: AI470274;
Proteins found in more fusions PRPF19 (see 2 fusions); NPM1 (see 1 fusions); HSF1 (see 3 fusions); YWHAH (see 2 fusions); WWP1 (see 1 fusions); OPTN (see 1 fusions); YWHAZ (see 1 fusions); IKBKB (see 2 fusions); PRDX6 (see 1 fusions); RPA1 (see 1 fusions); SF3A3/TOX4 (see 1 fusions); SNW1 (see 1 fusions); ARIH1 (see 4 fusions); PTBP1 (see 1 fusions); TNF (see 1 fusions); VCP (see 4 fusions); TKT (see 5 fusions); HSP90AA1 (see 2 fusions); HUWE1 (see 2 fusions); HSP90AB1 (see 1 fusions); COPS5/HNRNPH3 (see 3 fusions); CALR (see 6 fusions); EEF1D (see 3 fusions); NTRK1/TPM3 (see 3 fusions); HNRNPD (see 1 fusions); SNRNP200 (see 3 fusions); CLCN3 (see 3 fusions); BAG3 (see 4 fusions); STUB1 (see 1 fusions); EZH2 (see 1 fusions); KCMF1 (see 3 fusions); MME (see 1 fusions); EEF1A1 (see 1 fusions); RNF114 (see 1 fusions); HNRNPH3 (see 1 fusions); PRKCD (see 2 fusions); CUL3 (see 1 fusions); AHNAK (see 2 fusions); NAP1L1 (see 3 fusions); MYC (see 1 fusions); SMURF2 (see 1 fusions); ITPA (see 1 fusions); ACTN2 (see 1 fusions); COPS5 (see 1 fusions); UBC (see 1 fusions); PRPF40A (see 2 fusions); TP53 (see 3 fusions); SAT1 (see 5 fusions); ILK (see 1 fusions); AMD1 (see 1 fusions); ACTN1 (see 3 fusions); TPM3 (see 2 fusions); SQSTM1 (see 5 fusions); EIF4A2 (see 2 fusions); EGFR (see 2 fusions); CSRP1 (see 3 fusions); MCM2 (see 1 fusions); G6PD (see 3 fusions); MAP3K7 (see 7 fusions); CSNK1E (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AI470274chimera3640.03597869.703HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
2 AARSD1interactor80.4297.841tRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
3 ACAP2interactor100ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
PH (PF00169, IPR001849, SM00233): PH domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
BAR_3 (PF16746): BAR domain of APPL family
4 ACBD6interactor100ACBP (PF00887, IPR000582): Acyl CoA binding protein
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
5 ACTN1protein found in more fusions190.38643.816CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Dak2 (PF02734, IPR004007, SM01120): DAK2 domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
6 ACTN2protein found in more fusions90.5004.591CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Nsp1_C (PF05064, IPR007758): Nsp1-like C-terminal region
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
7 ACTN4interactor210.42435.441CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
8 ADCY9interactor100DUF1053 (PF06327, IPR009398): Domain of Unknown Function (DUF1053)
Phage_holin_3_6 (PF07332, IPR009937): Putative Actinobacterial Holin-X, holin superfamily III
DUF202 (PF02656, IPR003807): Domain of unknown function (DUF202)
Guanylate_cyc (PF00211, IPR001054, SM00044): Adenylate and Guanylate cyclase catalytic domain
zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type
AC_N (PF16214, IPR032628): Adenylyl cyclase N-terminal extracellular and transmembrane region
9 ADD3oncoprotein21.0000Aldolase_II (PF00596, IPR001303, SM01007): Class II Aldolase and Adducin N-terminal domain
10 ADPRHL2interactor100ADP_ribosyl_GH (PF03747, IPR005502): ADP-ribosylglycohydrolase
DUF4148 (PF13663, IPR025421): Domain of unknown function (DUF4148)
11 AGAP3interactor31.0000ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
PH (PF00169, IPR001849, SM00233): PH domain
Ras (PF00071, IPR001806, SM00173): Ras family
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
12 AGAP4interactor100ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
PH (PF00169, IPR001849, SM00233): PH domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
13 AGAP5interactor100ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
PH (PF00169, IPR001849, SM00233): PH domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
14 AHCYinteractor120.4918.842AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
15 AHNAKsuppressor310.308130.461DUF945 (PF06097, IPR010352): Bacterial protein of unknown function (DUF945)
ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
T2SSN (PF01203, IPR022792): Type II secretion system (T2SS), protein N
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
TT_ORF2a (PF08197, IPR013267): pORF2a truncated protein
DUF2993 (PF11209, IPR021373): Protein of unknown function (DUF2993)
DUF4097 (PF13349, IPR025164): Putative adhesin
Ntox37 (PF15535, IPR029108): Bacterial toxin 37
16 AKT1oncoprotein230.30394.675PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
17 ALPIinteractor21.0000Alk_phosphatase (PF00245, IPR001952, SM00098): Alkaline phosphatase
18 AMD1protein found in more fusions200SAM_decarbox (PF01536, IPR001985): Adenosylmethionine decarboxylase
19 ANAPC7interactor90.5003.929TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_21 (PF09976, IPR018704): Tetratricopeptide repeat-like domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
20 ANK1interactor31.0000Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
Death (PF00531, IPR000488, SM00005): Death domain
ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
21 ANXA1suppressor180.28734.783Annexin (PF00191, IPR018502, SM00335): Annexin
22 AP2B1interactor140.49510.459Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain
23 ARAFoncoprotein110.5274.780Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
24 ARHGDIAinteractor90.4646.435Rho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor
25 ARHGEF7interactor31.0000Borrelia_lipo_1 (PF05714, IPR008421): Borrelia burgdorferi virulent strain associated lipoprotein
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
RhoGEF67_u2 (PF16614): Unstructured region two on RhoGEF 6 and 7
RhoGEF67_u1 (PF16615): Unstructured region one on RhoGEF 6 and 7
26 ARIH1protein found in more fusions60.6001.221CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
Med14 (PF08638, IPR013947): Mediator complex subunit MED14
zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
27 ARMC6interactor40.6671.667Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Mis14 (PF08641, IPR013950): Kinetochore protein Mis14 like
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
28 ARMT1interactor50.4004.333DUF89 (PF01937, IPR002791): Protein of unknown function DUF89
29 ARRDC5interactor100Arc_trans_TRASH (PF08394, IPR013603): Archaeal TRASH domain
Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
30 ASB10interactor31.0000Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
31 ASB17interactor21.0000HTH_Mga (PF08280, IPR013199): M protein trans-acting positive regulator (MGA) HTH domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
SOCS_box (PF07525, IPR001496): SOCS box
32 ASB4interactor40.6671.167Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
33 ASB6interactor40.6670.833Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
34 ATF2oncoprotein180.21340.608bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
35 ATIConcoprotein140.24241.678AICARFT_IMPCHas (PF01808, IPR002695, SM00798): AICARFT/IMPCHase bienzyme
MGS (PF02142, IPR011607, SM00851): MGS-like domain
36 ATXN10interactor70.5711.091RIH_assoc (PF08454, IPR013662): RyR and IP3R Homology associated
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
37 BAG3oncoprotein460.130535.149BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
38 BICDL1interactor100DMPK_coil (PF08826, IPR014930): DMPK coiled coil domain like
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase
CALM_bind (PF16025): Calcium-dependent calmodulin binding
39 BTRConcoprotein300.214189.015WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
40 BUB1Boncoprotein110.37810.520Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1
Mad3_BUB1_II (PF08171, IPR012572): Mad3/BUB1 homology region 2
Pkinase (PF00069, IPR000719): Protein kinase domain
XhlA (PF10779, IPR019715): Haemolysin XhlA
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
41 BVESinteractor100Popeye (PF04831, IPR006916): Popeye protein conserved region
42 C11orf98interactor100DUF2156 (PF09924, IPR024320): Uncharacterised conserved protein (DUF2156)
43 C12orf10interactor50.6001.792UPF0160 (PF03690, IPR003226): Uncharacterised protein family (UPF0160)
44 C15orf57interactor100CCDC32 (PF14989, IPR028039): Coiled-coil domain containing 32
45 C2orf73interactor100GDWWSH (PF15667, IPR031365): Protein of unknown function with motif GDWWSH
46 CALRoncoprotein210.33758.546Calreticulin (PF00262, IPR001580): Calreticulin family
DDHD (PF02862, IPR004177, SM01127): DDHD domain
47 CAMK1interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
Tyrosinase (PF00264, IPR002227): Common central domain of tyrosinase
48 CARHSP1interactor40.5000.944DUF4339 (PF14237, IPR025640): Domain of unknown function (DUF4339)
49 CASP3interactor130.21241.800Peptidase_C14 (PF00656, IPR011600): Caspase domain
50 CBX1interactor40.6670.667Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
51 CCDC53interactor50.6003.500DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
52 CCDC70interactor100APG6 (PF04111, IPR007243): Autophagy protein Apg6
DUF4618 (PF15397, IPR029236): Domain of unknown function (DUF4618)
53 CCHCR1interactor60.5003.500HCR (PF07111, IPR009800): Alpha helical coiled-coil rod protein (HCR)
54 CCNCsuppressor40.5001.754Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
55 CCNDBP1suppressor30.6670.182CheF-arch (PF04283, IPR007381): Chemotaxis signal transduction system protein F from archaea
GCIP (PF13324): Grap2 and cyclin-D-interacting
56 CCNOinteractor100Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
57 CDC123interactor30.6670.222D123 (PF07065, IPR009772): D123
58 CDC5Linteractor580.254516.017OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
59 CDK5RAP3interactor60.7331.800DUF773 (PF05600, IPR008491): Protein of unknown function (DUF773)
60 CENPKinteractor100CENP-K (PF11802, IPR020993): Centromere-associated protein K
61 CEP57interactor130.30821.359Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
TRIQK (PF15168, IPR024842): Triple QxxK/R motif-containing protein family
62 CEP78interactor31.0000Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil
DUF3122 (PF11320, IPR021469): Protein of unknown function (DUF3122)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
63 CETN3interactor21.0000EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
DUF3741 (PF12552, IPR022212): Protein of unknown function (DUF3741)
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
64 CFTRsuppressor140.55116.103ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
65 CHUKsuppressor200.46837.746Pkinase (PF00069, IPR000719): Protein kinase domain
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
66 CLCN3protein found in more fusions31.0000CBS (PF00571, IPR000644, SM00116): CBS domain
Voltage_CLC (PF00654, IPR001807): Voltage gated chloride channel
67 COPS5protein found in more fusions600.220609.807JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
68 CPSF3interactor60.6670.679Lactamase_B (PF00753, IPR001279, SM00849): Metallo-beta-lactamase superfamily
RMMBL (PF07521, IPR011108): Zn-dependent metallo-hydrolase RNA specificity domain
Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain
CPSF73-100_C (PF11718, IPR021718, SM01098): Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term
Lactamase_B_3 (PF13483): Beta-lactamase superfamily domain
69 CRKoncoprotein190.31062.249SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
70 CRNKL1interactor70.7621.948NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference
HAT (PF02184, IPR003107, SM00386): HAT (Half-A-TPR) repeat
Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1
Suf (PF05843, IPR008847): Suppressor of forked protein (Suf)
U3_assoc_6 (PF08640, IPR013949): U3 small nucleolar RNA-associated protein 6
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
71 CRYAAoncoprotein51.0000Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
72 CRYABoncoprotein140.25650.730Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
73 CRYBB2interactor51.0000Crystall (PF00030, IPR001064, SM00247): Beta/Gamma crystallin
74 CRYGCinteractor51.0000Crystall (PF00030, IPR001064, SM00247): Beta/Gamma crystallin
75 CSinteractor80.4297.738Citrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain
76 CSNK1Eprotein found in more fusions100.5009.393APH (PF01636, IPR002575): Phosphotransferase enzyme family
Pkinase (PF00069, IPR000719): Protein kinase domain
77 CSRP1protein found in more fusions60.6001.069LIM (PF00412, IPR001781, SM00132): LIM domain
zf-MYND (PF01753, IPR002893): MYND finger
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
78 CUL3protein found in more fusions890.1641617.036Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
79 CYCSinteractor21.0000Cytochrom_C (PF00034, IPR003088): Cytochrome c
80 DAXXoncoprotein120.36417.990Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Nop14 (PF04147, IPR007276): Nop14-like family
RF-1 (PF00472, IPR000352): RF-1 domain
Vpu (PF00558, IPR008187): Vpu protein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
81 DESinteractor30.6670.500Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3
82 DFFAsuppressor50.7001.900CIDE-N (PF02017, IPR003508): CIDE-N domain
DFF-C (PF09033, IPR015121): DNA Fragmentation factor 45kDa, C terminal domain
T2SSppdC (PF12528, IPR022204): Type II secretion prepilin peptidase dependent protein C
SAPIS-gp6 (PF16722, IPR031999): Pathogenicity island protein gp6 in Staphylococcus
83 DMAP1interactor50.4003.619DMAP1 (PF05499, IPR008468): DNA methyltransferase 1-associated protein 1 (DMAP1)
SANT_DAMP1_like (PF16282, IPR032563): SANT/Myb-like domain of DAMP1
84 DMWDinteractor40.8330.069WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
85 DNAJC21interactor30.6671.000Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DUF788 (PF05620, IPR008506): Protein of unknown function (DUF788)
Sec62 (PF03839, IPR004728): Translocation protein Sec62
DUF2756 (PF10956, IPR020158): Protein of unknown function (DUF2756)
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
DBINO (PF13892, IPR020838): DNA-binding domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
86 DUTinteractor170.31640.793dUTPase (PF00692, IPR008180): dUTPase
87 EEF1A1suppressor430.331183.152GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
88 EEF1B2interactor160.6484.145EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
GST_C_6 (PF17171): Glutathione S-transferase, C-terminal domain
89 EEF1Dprotein found in more fusions210.42643.023EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
90 EFTUD2interactor300.44167.448EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
91 EGFRoncoprotein620.166884.125Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
92 EHD1interactor60.8000.284Gp-FAR-1 (PF05823, IPR008632): Nematode fatty acid retinoid binding protein (Gp-FAR-1)
Gtr1_RagA (PF04670, IPR006762): Gtr1/RagA G protein conserved region
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EHD_N (PF16880, IPR031692): N-terminal EH-domain containing protein
93 EIF1AXoncoprotein40.6671.000eIF-1a (PF01176, IPR006196): Translation initiation factor 1A / IF-1
94 EIF2S1interactor140.48413.925EIF_2_alpha (PF07541, IPR011488): Eukaryotic translation initiation factor 2 alpha subunit
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
95 EIF3Minteractor60.6671.520Death (PF00531, IPR000488, SM00005): Death domain
PCI (PF01399, IPR000717, SM00088): PCI domain
96 EIF4A2oncoprotein130.31823.671DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
97 EIF4Binteractor120.50912.265RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3774 (PF12609, IPR022251): Wound-induced protein
PROL5-SMR (PF15621, IPR026288): Proline-rich submaxillary gland androgen-regulated family
98 EIF4G2interactor120.54510.459MA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
99 EIF4G3interactor60.5331.721MA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
100 EIF5interactor130.6549.854CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region
eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
101 ENPP2oncoprotein100Endonuclease_NS (PF01223, IPR001604, SM00892): DNA/RNA non-specific endonuclease
Phosphodiest (PF01663, IPR002591): Type I phosphodiesterase / nucleotide pyrophosphatase
Somatomedin_B (PF01033, IPR001212, SM00201): Somatomedin B domain
102 EPB41L1interactor30.6670.3334_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
103 EPB41L2interactor41.00004_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
DUF966 (PF06136, IPR010369): Domain of unknown function (DUF966)
FA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
SAB (PF04382, IPR007477): SAB domain
TCP (PF03634, IPR005333): TCP family transcription factor
104 EPB41L3suppressor120.54516.1344_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
FA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SAB (PF04382, IPR007477): SAB domain
105 ERCC5oncoprotein1005_3_exonuc (PF01367, IPR020045, SM00475): 5'-3' exonuclease, C-terminal SAM fold
XPG_I (PF00867, IPR006086, SM00484): XPG I-region
XPG_N (PF00752, IPR006085, SM00485): XPG N-terminal domain
IZUMO (PF15005, IPR029389): Izumo sperm-egg fusion, Ig domain-associated
Codanin-1_C (PF15296, IPR028171): Codanin-1 C-terminus
EF-G-binding_N (PF07299): Elongation factor G-binding protein, N-terminal
106 ERICH6interactor100PDCD2_C (PF04194, IPR007320): Programmed cell death protein 2, C-terminal putative domain
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
AAA_23 (PF13476): AAA domain
FAM194 (PF14977, IPR029281): FAM194 protein
107 ERP29interactor40.6670.365ERp29 (PF07749, IPR011679): Endoplasmic reticulum protein ERp29, C-terminal domain
ERp29_N (PF07912, IPR012883): ERp29, N-terminal domain
108 ESR1suppressor530.187562.475Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
109 EZH2suppressor200.25168.217CDC45 (PF02724, IPR003874): CDC45-like protein
TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain
SET (PF00856, IPR001214, SM00317): SET domain
EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
110 FKBP4interactor160.50022.258FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
111 FLNBoncoprotein180.35944.818CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
PapC_N (PF13954, IPR025885): PapC N-terminal domain
112 FN1oncoprotein760.179937.049fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
113 FTH1interactor80.4297.739Coat_F (PF07875, IPR012851): Coat F domain
Ferritin (PF00210, IPR008331): Ferritin-like domain
114 FXR1interactor80.5244.089Agenet (PF05641, IPR008395, SM00743): Agenet domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
FXR_C3 (PF16097, IPR032177): Fragile X-related 1 protein C-terminal region 3
115 G6PDprotein found in more fusions160.58122.844G6PD_C (PF02781, IPR022675): Glucose-6-phosphate dehydrogenase, C-terminal domain
G6PD_N (PF00479, IPR022674): Glucose-6-phosphate dehydrogenase, NAD binding domain
116 GAPVD1interactor50.8000.605RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
VPS9 (PF02204, IPR003123, SM00167): Vacuolar sorting protein 9 (VPS9) domain
117 GARSinteractor80.4298.683HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
118 GATA1oncoprotein60.4674.867GATA (PF00320, IPR000679, SM00401): GATA zinc finger
Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain
119 GDI2interactor100.4675.639GDI (PF00996, IPR018203): GDP dissociation inhibitor
120 GLMNoncoprotein50.5002.089Kinetochor_Ybp2 (PF08568, IPR013877): Uncharacterised protein family, YAP/Alf4/glomulin
121 GLO1interactor110.34520.483Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
122 GLOD4interactor50.6002.233Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
123 GMPSoncoprotein110.4007.653GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
GMP_synt_C (PF00958, IPR001674): GMP synthase C terminal domain
NAD_synthase (PF02540, IPR022310): NAD synthase
124 GNPATinteractor31.0000Acyltransferase (PF01553, IPR002123, SM00563): Acyltransferase
125 GOLGA8Ainteractor100Phage_GP20 (PF06810, IPR009636): Phage minor structural protein GP20
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5
126 GRIPAP1interactor21.0000DivIC (PF04977, IPR007060): Septum formation initiator
HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7)
Rab5-bind (PF09311, IPR015390): Rabaptin-like protein
TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC)
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
JAKMIP_CC3 (PF16034, IPR031994): JAKMIP CC3 domain
ABC_tran_CTD (PF16326, IPR032524): ABC transporter C-terminal domain
127 GRK3interactor31.0000PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
128 GRPEL1interactor130.39420.511GrpE (PF01025, IPR000740): GrpE
129 GSTO1interactor70.3816.453GST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
130 GTSF1interactor100zf-U11-48K (PF05253, IPR022776): U11-48K-like CHHC zinc finger
131 GUCA1Ainteractor100Dockerin_1 (PF00404, IPR018242): Dockerin type I repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
132 HAUS1interactor140.23144.567THP2 (PF09432, IPR018557): Tho complex subunit THP2
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
133 HAUS8interactor21.0000DUF566 (PF04484, IPR007573): Family of unknown function (DUF566)
NdhN (PF11909, IPR020874): NADH-quinone oxidoreductase cyanobacterial subunit N
134 HDAC6oncoprotein260.39352.768Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP)
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
135 HDLBPoncoprotein120.42414.171BMC (PF00936, IPR000249, SM00877): BMC domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
KH_4 (PF13083): KH domain
KH_5 (PF13184, IPR025249): NusA-like KH domain
SLS (PF14611, IPR032741): Mitochondrial inner-membrane-bound regulator
DUF4530 (PF15039, IPR029202): Domain of unknown function (DUF4530)
136 HECTD1interactor70.5332.671Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
MIB_HERC2 (PF06701, IPR010606): Mib_herc2
NOA36 (PF06524, IPR010531): NOA36 protein
Sad1_UNC (PF07738, IPR012919): Sad1 / UNC-like C-terminal
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
137 HMGN5interactor100DUF2229 (PF09989, IPR018709): CoA enzyme activase uncharacterised domain (DUF2229)
HMG14_17 (PF01101, IPR000079, SM00527): HMG14 and HMG17
138 HN1interactor21.0000JUPITER (PF17054): Microtubule-Associated protein Jupiter
139 HN1Linteractor30.6670.667JUPITER (PF17054): Microtubule-Associated protein Jupiter
140 HNRNPA1interactor580.335394.138RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
141 HNRNPA2B1oncoprotein400.419118.009RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
142 HNRNPDoncoprotein350.399134.657CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
143 HNRNPFinteractor340.42868.456RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
144 HNRNPH1oncoprotein370.47986.272RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
145 HNRNPH2interactor200.57921.592RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
146 HNRNPH3protein found in more fusions240.54526.775Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
147 HNRNPUinteractor440.383196.833CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
148 HSF1protein found in more fusions140.41020.335DUF247 (PF03140, IPR004158): Plant protein of unknown function
Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
149 HSP90AA1oncoprotein710.210982.766HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
150 HSP90AB1oncoprotein500.326255.368HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
151 HSPA4interactor430.252349.969Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
152 HSPB6interactor31.0000Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
153 HSPB8interactor70.4675.944Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
154 HUWE1oncoprotein650.219682.426BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
155 IARS2interactor80.6071.641Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
156 IGBP1interactor100.26726.400TAP42 (PF04177, IPR007304): TAP42-like family
157 IGSF21interactor21.0000C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
158 IKBKBprotein found in more fusions170.45030.076FliT (PF05400, IPR008622): Flagellar protein FliT
Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
159 ILKsuppressor180.36832.261Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
160 INPP5Koncoprotein21.0000CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
161 INSinteractor21.0000Insulin (PF00049, IPR016179, SM00078): Insulin/IGF/Relaxin family
162 IPO7interactor130.41017.006Cse1 (PF08506, IPR013713): Cse1
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
DUF3730 (PF12530, IPR022542): Protein of unknown function (DUF3730)
163 IQCB1interactor210.26256.205DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765)
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit
164 IRAK1interactor210.40535.049Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
165 IRS4interactor190.45633.308CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
PH_11 (PF15413): Pleckstrin homology domain
166 ISG15suppressor260.23771.720ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
167 ISG20L2interactor100RNase_T (PF00929, IPR013520): Exonuclease
Glucosamine_iso (PF01182, IPR006148): Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
168 ITGA4interactor550.242366.114FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
169 ITPAprotein found in more fusions110.40013.245Ham1p_like (PF01725, IPR002637): Ham1 family
170 KCMF1oncoprotein120.40018.598zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
zf-LITAF-like (PF10601, IPR006629, SM00714): LITAF-like zinc ribbon domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Di19_C (PF14571, IPR027935): Stress-induced protein Di19, C-terminal
Ntox28 (PF15605, IPR028948): Bacterial toxin 28
171 KCTD3interactor50.5001.741BTB_2 (PF02214, IPR003131): BTB/POZ domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
172 KIAA0368interactor140.54912.221HEAT (PF02985, IPR000357): HEAT repeat
IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD)
CLASP_N (PF12348, IPR024395): CLASP N terminal
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal
Ecm29 (PF13001, IPR024372): Proteasome stabiliser
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
173 KLC1interactor60.7331.319Gly_radical (PF01228, IPR001150): Glycine radical
SOGA (PF11365, IPR027881): Protein SOGA
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
174 KNSTRNinteractor21.0000FlpD (PF02662, IPR003813): Methyl-viologen-reducing hydrogenase, delta subunit
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Matrilin_ccoil (PF10393, IPR019466): Trimeric coiled-coil oligomerisation domain of matrilin
175 KPNA3interactor70.4767.667Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
176 KRT18interactor180.28740.109Filament (PF00038, IPR001664): Intermediate filament protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
177 KRT72interactor21.0000Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
178 LASP1oncoprotein80.3578.141LIM (PF00412, IPR001781, SM00132): LIM domain
Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat
SH3_9 (PF14604, IPR001452): Variant SH3 domain
179 LBPinteractor30.6670.667LBP_BPI_CETP (PF01273, IPR017942, SM00328): LBP / BPI / CETP family, N-terminal domain
LBP_BPI_CETP_C (PF02886, IPR001124, SM00329): LBP / BPI / CETP family, C-terminal domain
180 LCE3Ainteractor100LCE (PF14672, IPR028205): Late cornified envelope
181 LIG1interactor21.0000DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region
DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain
DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Presenilin (PF01080, IPR001108): Presenilin
182 LIMK2interactor40.8330.111LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase (PF00069, IPR000719): Protein kinase domain
PP1_inhibitor (PF05361, IPR008025): PKC-activated protein phosphatase-1 inhibitor
183 LONRF1interactor200LON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
DZR (PF12773, IPR025874): Double zinc ribbon
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
TPR_19 (PF14559): Tetratricopeptide repeat
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
184 LRIF1interactor140.15447.855LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1
185 LUZP1interactor21.0000Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD
Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region
MerR-DNA-bind (PF09278, IPR015358): MerR, DNA binding
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
TMA7 (PF09072, IPR015157): Translation machinery associated TMA7
HD_assoc (PF13286, IPR026875): Phosphohydrolase-associated domain
DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
186 MAP3K7oncoprotein140.44914.159Mnd1 (PF03962, IPR005647): Mnd1 family
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
187 MCM2oncoprotein820.1971196.485AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
188 MCM6interactor160.45712.758MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
YmgB (PF10798, IPR024753): Biofilm development protein YmgB/AriR
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
189 MED31interactor50.4003.621Med31 (PF05669, IPR008831): SOH1
190 MFAP1interactor70.5244.868MFAP1 (PF06991, IPR009730): Microfibril-associated/Pre-mRNA processing
DUF3464 (PF11947, IPR021855): Protein of unknown function (DUF3464)
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
191 MMEsuppressor70.5332.471Peptidase_M13 (PF01431, IPR018497): Peptidase family M13
Peptidase_M13_N (PF05649, IPR008753): Peptidase family M13
192 MPHOSPH6interactor40.5000.952MPP6 (PF10175, IPR019324): M-phase phosphoprotein 6
193 MRGBPinteractor50.4004.125Eaf7 (PF07904, IPR012423): Chromatin modification-related protein EAF7
194 MRPL28interactor60.6673.062Ribosomal_L28 (PF00830, IPR001383): Ribosomal L28 family
195 MRPL40interactor50.4003.233MRP-L28 (PF09812, IPR019192): Mitochondrial ribosomal protein L28
196 MRPS23interactor120.48510.330MRP-S23 (PF10484, IPR023611): Mitochondrial ribosomal protein S23
197 MSL1interactor50.5003.286Herpes_UL6 (PF01763, IPR002660): Herpesvirus UL6 like
KLRAQ (PF10205, IPR019343): Predicted coiled-coil domain-containing protein
PEHE (PF15275, IPR029332): PEHE domain
MSL1_dimer (PF16801, IPR031840): Dimerisation domain of Male-specific-Lethal 1
198 MSNoncoprotein160.41022.256DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
199 MTIF2interactor100GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
IF-2 (PF11987, IPR023115): Translation-initiation factor 2
200 MYConcoprotein440.215367.609HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
201 MYL12Ainteractor80.42911.952EF-hand_11 (PF08976, IPR015070): EF-hand domain
DUF2267 (PF10025, IPR018727): Uncharacterized conserved protein (DUF2267)
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
202 MYL12Binteractor50.6001.119EF-hand_11 (PF08976, IPR015070): EF-hand domain
EF-hand_6 (PF13405, IPR002048): EF-hand domain
DDE_Tnp_IS66_C (PF13817): IS66 C-terminal element
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
203 MYL9interactor40.6670.583UPF0154 (PF03672, IPR005359): Uncharacterised protein family (UPF0154)
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
204 MYLKinteractor31.0000Amelogenin (PF02948, IPR004116, SM00818): Amelogenin
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase (PF00069, IPR000719): Protein kinase domain
23ISL (PF16620): Unstructured linker between I-set domains 2 and 3 on MYLCK
205 NAMPTinteractor41.0000NAPRTase (PF04095, IPR007229): Nicotinate phosphoribosyltransferase (NAPRTase) family
206 NAP1L1protein found in more fusions160.43820.235NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
207 NBASinteractor21.0000PMEI (PF04043, IPR006501, SM00856): Plant invertase/pectin methylesterase inhibitor
Sec39 (PF08314, IPR013244): Secretory pathway protein Sec39
SLX9 (PF15341): Ribosome biogenesis protein SLX9
Nbas_N (PF15492, IPR029145): Neuroblastoma-amplified sequence, N terminal
208 NCKIPSDoncoprotein50.5002.755DUF2013 (PF09431, IPR018556): Protein of unknown function (DUF2013)
Rcd1 (PF04078, IPR007216): Cell differentiation family, Rcd1-like
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
209 NEK10interactor100Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATP-cone (PF03477, IPR005144): ATP cone domain
Pkinase (PF00069, IPR000719): Protein kinase domain
210 NEXNinteractor100Cas_Csy4 (PF09618, IPR013396): CRISPR-associated protein (Cas_Csy4)
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
VIT (PF08487, IPR013694, SM00609): Vault protein inter-alpha-trypsin domain
DUF2951 (PF11166, IPR021337): Protein of unknown function (DUF2951)
Med2 (PF11214, IPR021017): Mediator complex subunit 2
DUF2897 (PF11446, IPR021550): Protein of unknown function (DUF2897)
DUF3824 (PF12868, IPR024436): Domain of unknwon function (DUF3824)
DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355)
Casc1_N (PF15927, IPR031826): Cancer susceptibility candidate 1 N-terminus
Connexin40_C (PF16791, IPR031862): Connexin 40 C-terminal domain
211 NFU1interactor100Nfu_N (PF08712, IPR014824, SM00932): Scaffold protein Nfu/NifU N terminal
NifU (PF01106, IPR001075): NifU-like domain
212 NOS2interactor250.38442.135FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
213 NPM1suppressor570.290453.975Nucleoplasmin (PF03066): Nucleoplasmin
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
214 NRDCinteractor50.6670.810Cnd2 (PF05786, IPR022816): Condensin complex subunit 2
Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
Tom22 (PF04281, IPR005683): Mitochondrial import receptor subunit Tom22
Peptidase_M16_M (PF16187, IPR032632): Middle or third domain of peptidase_M16
215 NSMCE4Ainteractor100Nse4_C (PF08743, IPR014854): Nse4 C-terminal
Nse4-Nse3_bdg (PF15412, IPR029225): Binding domain of Nse4/EID3 to Nse3-MAGE
216 NTRK1oncoprotein1340.1065156.403I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
217 NVLinteractor41.0000AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
SRPRB (PF09439, IPR019009): Signal recognition particle receptor beta subunit
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
AAA_16 (PF13191): AAA ATPase domain
AAA_17 (PF13207): AAA domain
Nucleolin_bd (PF16725, IPR031996): Nucleolin binding domain
218 OBSL1interactor520.249330.510BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
219 OLA1interactor100.4894.324Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
YchF-GTPase_C (PF06071, IPR013029): Protein of unknown function (DUF933)
220 OPTNprotein found in more fusions100.55610.061ARD (PF03079, IPR004313): ARD/ARD' family
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
221 OSBPL9interactor30.6670.400Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein
PH (PF00169, IPR001849, SM00233): PH domain
Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
222 OXCT1interactor90.35711.181CoA_trans (PF01144, IPR004165, SM00882): Coenzyme A transferase
223 PAF1oncoprotein90.5288.323Paf1 (PF03985, IPR007133): Paf1
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
224 PAICSinteractor160.36232.423AIRC (PF00731, IPR000031, SM01001): AIR carboxylase
SAICAR_synt (PF01259, IPR028923): SAICAR synthetase
225 PALM3interactor100Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
226 PCSK9interactor30.6670.667Peptidase_S8 (PF00082, IPR000209): Subtilase family
Inhibitor_I9 (PF05922, IPR010259): Peptidase inhibitor I9
227 PDLIM1interactor100.36115.093LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
228 PELOinteractor80.5362.449eRF1_1 (PF03463, IPR005140): eRF1 domain 1
eRF1_2 (PF03464, IPR005141): eRF1 domain 2
eRF1_3 (PF03465, IPR005142): eRF1 domain 3
229 PEX19interactor40.6670.170Pex19 (PF04614, IPR006708): Pex19 protein family
Rod-binding (PF10135, IPR019301): Rod binding protein
230 PFDN2interactor90.27814.891Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
231 PGM2interactor40.6670.480PGM_PMM_I (PF02878, IPR005844): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
PGM_PMM_II (PF02879, IPR005845): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
PGM_PMM_III (PF02880, IPR005846): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
PGM_PMM_IV (PF00408, IPR005843): Phosphoglucomutase/phosphomannomutase, C-terminal domain
232 PHLDA1oncoprotein31.0000Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
PH (PF00169, IPR001849, SM00233): PH domain
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
TonB_N (PF16031): TonB N-terminal region
233 PITPNAoncoprotein100IP_trans (PF02121, IPR001666): Phosphatidylinositol transfer protein
234 PITPNBinteractor31.0000IP_trans (PF02121, IPR001666): Phosphatidylinositol transfer protein
235 PKMoncoprotein320.37998.673PK (PF00224, IPR015793): Pyruvate kinase, barrel domain
PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
236 PLGinteractor21.0000Kringle (PF00051, IPR000001): Kringle domain
PAN_1 (PF00024, IPR003014): PAN domain
Trypsin (PF00089, IPR001254, SM00020): Trypsin
237 PNISRinteractor40.5001.111DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Pap_E4 (PF02711, IPR003861): E4 protein
Membralin (PF09746, IPR019144): Tumour-associated protein
YqfQ (PF14181, IPR025571): YqfQ-like protein
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
238 PNPT1interactor40.6671.400PNPase (PF03726, IPR015848): Polyribonucleotide nucleotidyltransferase, RNA binding domain
RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
239 PPA1interactor90.4725.950Pyrophosphatase (PF00719, IPR008162): Inorganic pyrophosphatase
240 PPM1Asuppressor40.5001.025PP2C (PF00481, IPR001932): Protein phosphatase 2C
PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
241 PPP2R3Cinteractor21.0000DUF61 (PF01886, IPR002746): Protein of unknown function DUF61
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
242 PRDX6protein found in more fusions140.41019.788AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
243 PRKCDsuppressor160.43825.575Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
244 PRKD1oncoprotein70.7330.371PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
245 PRPF19protein found in more fusions320.46286.859Prp19 (PF08606, IPR013915): Prp19/Pso4-like
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
246 PRPF40Aprotein found in more fusions180.6477.736FF (PF01846, IPR002713, SM00441): FF domain
MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain
Transformer (PF06495, IPR010519): Fruit fly transformer protein
WW (PF00397, IPR001202, SM00456): WW domain
YqzE (PF14038, IPR025622): YqzE-like protein
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus
SOBP (PF15279, IPR026092): Sine oculis-binding protein
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
247 PSMA3interactor480.263361.835Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
248 PSMA6interactor280.40572.691Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
249 PSMB2interactor160.51720.659Proteasome (PF00227, IPR001353): Proteasome subunit
250 PSMC1interactor220.50632.639AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
DivIC (PF04977, IPR007060): Septum formation initiator
DUF815 (PF05673, IPR008533): Protein of unknown function (DUF815)
Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
251 PSMD1interactor260.46847.344PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin)
PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
HEAT_2 (PF13646): HEAT repeats
252 PTBP1oncoprotein270.53242.655RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
253 PTGES3interactor210.42644.990CS (PF04969, IPR007052): CS domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
254 PTPN3interactor40.6670.508FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
255 PTPRAinteractor21.0000DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
256 PUM1interactor90.5286.009K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PUF (PF00806, IPR001313, SM00025): Pumilio-family RNA binding repeat
YppG (PF14179, IPR025555): YppG-like protein
257 RAB41oncoprotein100Ras (PF00071, IPR001806, SM00173): Ras family
258 RAD23Aoncoprotein190.51025.925UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
259 RALAoncoprotein30.6670.250ArgK (PF03308, IPR005129): ArgK protein
Ras (PF00071, IPR001806, SM00173): Ras family
ThiF (PF00899, IPR000594): ThiF family
260 RASSF9interactor31.0000RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
Spore_III_AB (PF09548, IPR014198): Stage III sporulation protein AB (spore_III_AB)
DUF3087 (PF11286, IPR021438): Protein of unknown function (DUF3087)
261 RBM25interactor120.6214.398Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
PWI (PF01480, IPR002483, SM00311): PWI domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
DUF3441 (PF11923, IPR021846): Domain of unknown function (DUF3441)
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4778 (PF16008, IPR031958): Domain of unknown function (DUF4778)
262 RBM39oncoprotein270.49664.833RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
263 RBM48interactor70.2867.993DUF2284 (PF10050, IPR019271): Predicted metal-binding protein (DUF2284)
264 RBPJinteractor60.5331.343BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain
LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding
TIG (PF01833, IPR002909): IPT/TIG domain
265 RBX1oncoprotein160.30546.172zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
266 RNF114protein found in more fusions50.6670.224zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
267 RPA1suppressor430.372150.720Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
268 RPA2oncoprotein420.345231.795RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
269 RPA3interactor370.386104.245Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
270 RPAP3interactor90.5565.639TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
RPAP3_C (PF13877, IPR025986): Potential Monad-binding region of RPAP3
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
271 RPSAinteractor250.50046.271Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
272 RSPH3interactor100Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3
273 RYBPinteractor31.0000DUF11 (PF01345, IPR001434): Domain of unknown function DUF11
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PPAK (PF02818, IPR004168): PPAK motif
Titin_Z (PF09042, IPR015129): Titin Z
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ig_3 (PF13927): Immunoglobulin domain
274 S100A4interactor40.6671.500S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
275 SARSinteractor110.47311.361NOD (PF06816, IPR010660): NOTCH protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
276 SAT1protein found in more fusions80.28610.952Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
277 SBF1interactor21.0000dDENN (PF03455, IPR005112, SM00801): dDENN domain
DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain
GRAM (PF02893, IPR004182, SM00568): GRAM domain
Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
PH (PF00169, IPR001849, SM00233): PH domain
uDENN (PF03456, IPR005113, SM00800): uDENN domain
T2SSJ (PF11612, IPR010055): Type II secretion system (T2SS), protein J
SBF2 (PF12335, IPR022096): Myotubularin protein
278 SDHAsuppressor140.34135.586FAD_binding_2 (PF00890, IPR003953): FAD binding domain
Succ_DH_flav_C (PF02910, IPR015939): Fumarate reductase flavoprotein C-term
279 SEC13interactor120.34514.928WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
280 SEPHS1interactor100.36116.741AIRS (PF00586, IPR000728): AIR synthase related protein, N-terminal domain
AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain
281 SERTAD1interactor21.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
SERTA (PF06031, IPR009263): SERTA motif
282 SF3A3protein found in more fusions200.43239.914DUF3449 (PF11931, IPR024598): Domain of unknown function (DUF3449)
SF3a60_bindingd (PF12108, IPR021966): Splicing factor SF3a60 binding domain
Telomere_Sde2_2 (PF13297): Telomere stability C-terminal
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
SF3A3 (PF16837, IPR031774): Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9
283 SF3B3interactor200.63712.144CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
284 SLC7A9interactor100AA_permease_2 (PF13520, IPR002293): Amino acid permease
UPF0542 (PF15086, IPR027877): Uncharacterised protein family UPF0542
285 SMARCA2suppressor90.44412.294DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
BRK (PF07533, IPR006576, SM00592): BRK domain
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
286 SMARCA4suppressor180.34648.802DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
BRK (PF07533, IPR006576, SM00592): BRK domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065)
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
287 SMARCD1interactor130.35929.653ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit
DivIC (PF04977, IPR007060): Septum formation initiator
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
288 SMN1interactor240.28999.107SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
289 SMURF2protein found in more fusions80.3816.408C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
290 SNRNP200protein found in more fusions320.48456.598DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603
Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
291 SNW1protein found in more fusions520.249442.282SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
292 SOX2oncoprotein230.173122.177HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
293 SPACA7interactor100PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
SPACA7 (PF15307, IPR029301): Sperm acrosome-associated protein 7
294 SPATA7interactor100HSD3 (PF15244, IPR029357): Spermatogenesis-associated protein 7, or HSD3
295 SPIN1interactor70.5712.397Spin-Ssty (PF02513, IPR003671): Spin/Ssty Family
296 SPTBN1suppressor150.45717.178CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Spectrin (PF00435, IPR002017): Spectrin repeat
PH_9 (PF15410): Pleckstrin homology domain
297 SQSTM1oncoprotein300.305118.270PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
UBA_5 (PF16577, IPR015940): UBA domain
298 SRMSinteractor100Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
299 SRP72interactor120.59110.437BTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain
SRP72 (PF08492, IPR013699): SRP72 RNA-binding domain
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat
300 SRRM2interactor390.339147.672cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Pap_E4 (PF02711, IPR003861): E4 protein
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
301 STAT2oncoprotein50.7000.737SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
STAT2_C (PF12188, IPR022756): Signal transducer and activator of transcription 2 C terminal
302 STIP1interactor310.318143.380TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
Wtap (PF17098, IPR029732): Pre-mRNA-splicing regulator WTAP
303 STMN1interactor180.28863.400Stathmin (PF00836, IPR000956): Stathmin family
304 STRNoncoprotein40.6670.439CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like
Striatin (PF08232, IPR013258): Striatin family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
305 STUB1suppressor330.292168.152U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
306 SUPT5Hinteractor100.4448.107KOW (PF00467, IPR005824, SM00739): KOW motif
Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
307 SYCE1interactor40.6671.167CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
SYCE1 (PF15233, IPR026676): Synaptonemal complex central element protein 1
308 TARBP2interactor41.0000dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
309 TARDBPinteractor380.429106.458RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
310 TARSinteractor160.37526.689HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain
TGS (PF02824, IPR004095): TGS domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
311 TBC1D1interactor31.0000DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
IncA (PF04156, IPR007285): IncA protein
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
DUF3350 (PF11830, IPR021785): Domain of unknown function (DUF3350)
FANCI_S1-cap (PF14674, IPR029305): FANCI solenoid 1 cap
312 TESsuppressor40.5002.400LIM (PF00412, IPR001781, SM00132): LIM domain
PET (PF06297, IPR010442): PET Domain
PSCyt3 (PF07627, IPR013039): Protein of unknown function (DUF1588)
Ig_Tie2_1 (PF10430, IPR018941): Tie-2 Ig-like domain 1
313 TGFB1I1interactor21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
314 THOC5oncoprotein30.6670.333FimP (PF09766, IPR019163): Fms-interacting protein
315 TJP2oncoprotein90.5008.737PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
316 TKTprotein found in more fusions250.301114.224Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
Transketolase_N (PF00456, IPR005474): Transketolase, thiamine diphosphate binding domain
317 TMCO3interactor21.0000DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
IL3 (PF02059, IPR002183): Interleukin-3
Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
318 TNFoncoprotein110.4679.968TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
319 TOMM70interactor70.6192.322PBP_GOBP (PF01395, IPR006170, SM00708): PBP/GOBP family
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
NRBF2_MIT (PF17169): MIT domain of nuclear receptor-binding factor 2
320 TOX4protein found in more fusions70.6001.223Extensin_2 (PF04554, IPR006706): Extensin-like region
FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
YABBY (PF04690, IPR006780): YABBY protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
321 TP53suppressor640.181933.447DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
322 TPM3oncoprotein210.33770.722Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
323 TPT1interactor50.4001.747TCTP (PF00838, IPR018105): Translationally controlled tumour protein
324 TRIM24suppressor50.6670.123PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Siva (PF05458, IPR022773): Cd27 binding protein (Siva)
zf-MYND (PF01753, IPR002893): MYND finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
Imm68 (PF15583, IPR028276): Immunity protein 68
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
325 TRIM54interactor60.5003.333DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349)
zf-HIT (PF04438, IPR007529): HIT zinc finger
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
326 TSNAXIP1interactor100MRP-L47 (PF06984, IPR010729): Mitochondrial 39-S ribosomal protein L47 (MRP-L47)
XH (PF03469, IPR005379): XH domain
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
DUF4600 (PF15372, IPR028022): Domain of unknown function (DUF4600)
TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus
327 TTC3interactor30.6670.250DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
NuiA (PF07924, IPR012489): Nuclease A inhibitor-like protein
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
ALMT (PF11744, IPR020966): Aluminium activated malate transporter
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
DUF3987 (PF13148, IPR025048): Protein of unknown function (DUF3987)
FlxA (PF14282, IPR025577): FlxA-like protein
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
DUF4446 (PF14584, IPR027981): Protein of unknown function (DUF4446)
328 TTC39Cinteractor100TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
Deme6 (PF10300, IPR019412): Protein of unknown function (DUF3808)
329 TUBA1Cinteractor260.41551.846Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
330 TUBA4Ainteractor270.33383.818Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
331 TXNL1interactor150.55218.186PITH (PF06201, IPR010400): PITH domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
332 UAP1interactor31.0000UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase
333 UBA2interactor100.4898.093ThiF (PF00899, IPR000594): ThiF family
UAE_UbL (PF14732, IPR028077): Ubiquitin/SUMO-activating enzyme ubiquitin-like domain
UBA2_C (PF16195, IPR032426): SUMO-activating enzyme subunit 2 C-terminus
334 UBCprotein found in more fusions630.226774.427ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
335 UBE2G2interactor90.3935.617UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
336 UBL4Ainteractor260.35171.434ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
337 UCHL5oncoprotein290.315139.035Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
338 UFD1Linteractor110.49112.258UFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1
339 UGDHinteractor60.6001.8133HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
UDPG_MGDP_dh (PF00984, IPR014026): UDP-glucose/GDP-mannose dehydrogenase family, central domain
UDPG_MGDP_dh_C (PF03720, IPR014027, SM00984): UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain
UDPG_MGDP_dh_N (PF03721, IPR001732): UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain
340 UNGinteractor41.0000UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily
341 UQCC2interactor100Complex1_LYR (PF05347, IPR008011): Complex 1 protein (LYR family)
342 UQCRBinteractor30.6670.667UCR_14kD (PF02271, IPR003197): Ubiquinol-cytochrome C reductase complex 14kD subunit
343 USP14interactor120.7423.560UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
344 VCAM1interactor480.259216.638C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
345 VCPprotein found in more fusions660.255656.649AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
346 VIMsuppressor320.247173.451Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
347 WDR66interactor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
348 WDR83interactor70.3817.238WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
349 WWOXsuppressor230.27375.539adh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain
350 WWP1oncoprotein70.3331.877C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
351 XPO1interactor780.1151844.465CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
352 XRCC5suppressor330.268147.029Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
353 YWHABinteractor350.274232.39414-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
354 YWHAEoncoprotein440.303277.55614-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
355 YWHAHprotein found in more fusions220.53831.21714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
356 YWHAQinteractor500.228496.75114-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
357 YWHAZprotein found in more fusions480.277347.69514-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
358 ZBTB1interactor60.4672.417BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
359 ZBTB17interactor70.8000.269BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
360 ZBTB37interactor100BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
361 ZFATinteractor100ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
AT_hook (PF02178, IPR017956, SM00384): AT hook motif
zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
362 ZNF131interactor40.5001.889BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
PVL_ORF50 (PF07768, IPR011688): PVL ORF-50-like family
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
363 ZNF197interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
364 ZNRF3interactor100PA (PF02225, IPR003137): PA domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Cadherin_C_2 (PF16492, IPR032455): Cadherin cytoplasmic C-terminal
zf-C3H2C3 (PF17122, IPR001841): Zinc-finger
365 ZYXsuppressor110.40019.169DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
LIM (PF00412, IPR001781, SM00132): LIM domain
DUF2757 (PF10955, IPR020115): Protein of unknown function (DUF2757)

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 AATKinteractorPkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
2 AGAP10PinteractorNA
3 AGAP7PinteractorNA
4 ANKRD7interactorAnk_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
5 ARHGAP28interactorRhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
6 CDK1oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
7 FAM71DinteractorDUF3699 (PF12480, IPR022168): Protein of unknown function (DUF3699)
8 FARP2parental proteinFA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
9 HSPA5oncoproteinHSP70 (PF00012, IPR013126): Hsp70 protein
10 HSPA8oncoproteinHSP70 (PF00012, IPR013126): Hsp70 protein
11 HSPA9oncoproteinHSP70 (PF00012, IPR013126): Hsp70 protein
12 HSPB1parental proteinHSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
13 KANSL1interactorPEHE (PF15275, IPR029332): PEHE domain
14 LSM3interactorLSM (PF01423, IPR001163): LSM domain
15 MAGED1interactorMAGE (PF01454, IPR002190): MAGE family
16 MAPKAPK2oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
17 MAPKAPK3interactorPkinase (PF00069, IPR000719): Protein kinase domain
18 MAPKAPK5interactorPkinase (PF00069, IPR000719): Protein kinase domain
19 NAPAoncoproteinSNAP (PF14938): Soluble NSF attachment protein, SNAP
20 PALLDinteractorI-set (PF07679, IPR013098): Immunoglobulin I-set domain
21 PDZK1interactorPDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DUF4265 (PF14085, IPR025361): Domain of unknown function (DUF4265)
22 PHYHIPLinteractorfn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
23 PSAT1interactorAminotran_5 (PF00266, IPR000192): Aminotransferase class-V
24 PTGER3interactor7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
FtsX (PF02687, IPR003838): FtsX-like permease family
25 SIK2interactorPkinase (PF00069, IPR000719): Protein kinase domain
26 SNCAinteractorSynuclein (PF01387, IPR001058): Synuclein
27 SNRPFinteractorLSM (PF01423, IPR001163): LSM domain
28 TBC1D3BinteractorRabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
29 TCPTinteractorNA
30 TYK2interactorPkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
31 UBE2IinteractorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
32 UBE2NinteractorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
33 USP1interactorUCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
34 USP38oncoproteinUCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase

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