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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: AI110770 is the fusion of parental proteins MED20, AKR1A1 (from a repository: Mon Oct 14 16:21:44 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)27
The number (and %) of the onco-proteins6 (22.22 %)
The number (and %) of the tumor suppressors1 (3.70 %)
Total number of binary PPIs (saturation %)95 (27.07 %)
The number (and %) of affected PPIs26 (27.37 %)
The number of possible different fusions4
PPI diameter2
PPI radius1
The average degree of PPI6.519
Assortativity coefficient-0.2861
The network average Clustering coefficient0.644
The number (and %) of a zero Clustering coefficients2 (7.41 %)
The number (and %) of a zero Betweenness Centrality8 (29.63 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: MED20,AKR1A1 All fusions
: AI110770;
Proteins found in more fusions TKT (see 5 fusions); TERF2IP (see 1 fusions); GAPDH (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AI110770chimera270.191361.486Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
2 AKR1B1suppressor90.41719.167Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
3 ARFIP1interactor100Arfaptin (PF06456, IPR010504, SM01015): Arfaptin-like domain
4 C11orf54interactor40.8330.667DUF1907 (PF08925, IPR015021, SM01168): Domain of Unknown Function (DUF1907)
5 CFL1interactor110.54516.619Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
6 DAZAP1interactor100.48915.633RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
7 EXOSC4interactor200RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2
8 GAPDHoncoprotein80.7622.333Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
9 GNPDA2interactor40.6671.500Glucosamine_iso (PF01182, IPR006148): Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
10 GPIinteractor21.0000PGI (PF00342, IPR001672): Phosphoglucose isomerase
11 GRHPRinteractor30.6670.5002-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
12 MEMO1interactor31.0000DUF11 (PF01345, IPR001434): Domain of unknown function DUF11
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PPAK (PF02818, IPR004168): PPAK motif
Titin_Z (PF09042, IPR015129): Titin Z
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ig_3 (PF13927): Immunoglobulin domain
13 NANSinteractor41.0000NeuB (PF03102, IPR013132): NeuB family
SAF (PF08666, IPR013974, SM00858): SAF domain
14 NME1-NME2interactor90.50012.300NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
15 NME2interactor70.9330.400NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
16 PCBP1oncoprotein80.6436.800Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
17 PGK1interactor50.8001.167PGK (PF00162, IPR001576): Phosphoglycerate kinase
18 PGK2interactor21.0000PGK (PF00162, IPR001576): Phosphoglycerate kinase
19 PKMoncoprotein90.6396.933PK (PF00224, IPR015793): Pyruvate kinase, barrel domain
PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
20 PTGR1interactor21.0000ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
ADH_N_2 (PF16884): N-terminal domain of oxidoreductase
21 SNX12interactor40.5001.619PX (PF00787, IPR001683, SM00312): PX domain
22 SNX3interactor30.6670.286PX (PF00787, IPR001683, SM00312): PX domain
23 SOD1interactor120.50917.219Sod_Cu (PF00080, IPR001424): Copper/zinc superoxide dismutase (SODC)
24 TALDO1interactor70.5715.652TAL_FSA (PF00923, IPR001585): Transaldolase/Fructose-6-phosphate aldolase
25 TERF1interactor80.6675.067TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
26 TERF2IPprotein found in more fusions41.0000BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
Histone_HNS (PF00816, IPR001801): H-NS histone family
Myb_DNA-bind_2 (PF08914, IPR015010): Rap1 Myb domain
Rap1_C (PF11626, IPR021661): TRF2-interacting telomeric protein/Rap1 - C terminal domain
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
27 TKTprotein found in more fusions170.40050.652Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
Transketolase_N (PF00456, IPR005474): Transketolase, thiamine diphosphate binding domain

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ACAT2interactorThiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
2 AFG3L2interactorAAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
FtsH_ext (PF06480, IPR011546): FtsH Extracellular
Peptidase_M41 (PF01434, IPR000642): Peptidase family M41
TniB (PF05621, IPR008868): Bacterial TniB protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
3 AKR1A1parental proteinAldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
4 ALBinteractorSerum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
5 ARF4interactorArf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
6 ARF5interactorArf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
7 ATP5C1interactorATP-synt (PF00231, IPR000131): ATP synthase
ACT_4 (PF13291, IPR002912): ACT domain
8 ATP5F1interactorMt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
DUF2105 (PF09878, IPR019212): Predicted membrane protein (DUF2105)
9 ATP6V1E1interactorvATP-synt_E (PF01991, IPR002842): ATP synthase (E/31 kDa) subunit
10 ATP6V1HinteractorV-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
11 ATPIF1interactorDivIC (PF04977, IPR007060): Septum formation initiator
IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
12 BAG6interactorDUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
13 C21orf33interactorDJ-1_PfpI (PF01965, IPR002818): DJ-1/PfpI family
14 C3interactorA2M (PF00207, IPR001599): Alpha-2-macroglobulin family
A2M_comp (PF07678, IPR011626): A-macroglobulin complement component
A2M_N (PF01835, IPR002890): MG2 domain
A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region
A2M_recep (PF07677, IPR009048): A-macroglobulin receptor
ANATO (PF01821, IPR000020, SM00104): Anaphylotoxin-like domain
NTR (PF01759, IPR018933, SM00206): UNC-6/NTR/C345C module
Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region
15 CCNCsuppressorCyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
16 CD300CinteractorV-set (PF07686, IPR013106): Immunoglobulin V-set domain
17 CDK19interactorPex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Pkinase (PF00069, IPR000719): Protein kinase domain
18 CDK8interactorPkinase (PF00069, IPR000719): Protein kinase domain
19 CKAP2interactorLy49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
MGC-24 (PF05283, IPR007947): Multi-glycosylated core protein 24 (MGC-24), sialomucin
CKAP2_C (PF15297, IPR029197): Cytoskeleton-associated protein 2 C-terminus
20 CNPinteractorCNPase (PF05881, IPR008431): 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
NB-ARC (PF00931, IPR002182): NB-ARC domain
AAA_33 (PF13671): AAA domain
21 CORO1ConcoproteinDUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
WD40_4 (PF16300): Type of WD40 repeat
22 CPinteractorCu-oxidase (PF00394, IPR001117): Multicopper oxidase
Cu-oxidase_2 (PF07731, IPR011706): Multicopper oxidase
Cu-oxidase_3 (PF07732, IPR011707): Multicopper oxidase
23 CPSF7interactorCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
24 CSNK2A2interactorPkinase (PF00069, IPR000719): Protein kinase domain
25 CYCSinteractorCytochrom_C (PF00034, IPR003088): Cytochrome c
26 DNAJB1suppressorDnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
27 ECH1interactorECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
28 ECHS1interactorECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
29 ELAVL1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
30 EPAS1suppressorCorona_I (PF03187, IPR004876): Corona nucleocapsid I protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
PAS_11 (PF14598): PAS domain
31 ESR1suppressorOest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
32 ESR2suppressorzf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ERbeta_N (PF12497, IPR021064): Estrogen receptor beta
33 EXOSC8interactorRNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2
34 FAM50AinteractorXAP5 (PF04921, IPR007005): XAP5, circadian clock regulator
DUF3824 (PF12868, IPR024436): Domain of unknwon function (DUF3824)
CSRNP_N (PF16019, IPR031972): Cysteine/serine-rich nuclear protein N-terminus
35 FBXW7suppressorMem_trans (PF03547, IPR004776): Membrane transport protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
F-box-like (PF12937, IPR001810): F-box-like
36 FKBP1AinteractorFKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
Hemopexin (PF00045, IPR018487, SM00120): Hemopexin
37 FLIIoncoproteinGelsolin (PF00626, IPR007123): Gelsolin repeat
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
38 GNG12interactorG-gamma (PF00631, IPR015898, SM00224): GGL domain
39 GNPDA1interactorGlucosamine_iso (PF01182, IPR006148): Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
40 GSTO1interactorGST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
41 GTF2F1interactorTFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
42 GTPBP4suppressorDUF258 (PF03193, IPR004881): Protein of unknown function, DUF258
MRC1 (PF09444, IPR018564): MRC1-like domain
NOG1 (PF06858, IPR010674): Nucleolar GTP-binding protein 1 (NOG1)
NOGCT (PF08155, IPR012973): NOGCT (NUC087) domain
Lip_prot_lig_C (PF10437, IPR019491): Bacterial lipoate protein ligase C-terminus
AAA_16 (PF13191): AAA ATPase domain
43 HUWE1oncoproteinBUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
44 IGF2BP3interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
KH_1 (PF00013, IPR004088, SM00322): KH domain
KH_4 (PF13083): KH domain
45 IGHG2oncoproteinC1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
46 KCMF1oncoproteinzf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
zf-LITAF-like (PF10601, IPR006629, SM00714): LITAF-like zinc ribbon domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Di19_C (PF14571, IPR027935): Stress-induced protein Di19, C-terminal
Ntox28 (PF15605, IPR028948): Bacterial toxin 28
47 LRRC47interactorB3_4 (PF03483, IPR005146, SM00873): B3/4 domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
48 MANFoncoproteinArmet (PF10208, IPR019345): Degradation arginine-rich protein for mis-folding
49 MDH1interactorLdh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
50 MED1interactorVfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Med1 (PF10744, IPR019680): Mediator of RNA polymerase II transcription subunit 1
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
51 MED10interactorMed10 (PF09748, IPR019145): Transcription factor subunit Med10 of Mediator complex
52 MED11interactorMed11 (PF10280, IPR019404): Mediator complex protein
53 MED12oncoproteinMed12 (PF09497, IPR019035): Transcription mediator complex subunit Med12
Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877)
Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain
Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
54 MED14interactorMed14 (PF08638, IPR013947): Mediator complex subunit MED14
55 MED15interactorMed15 (PF09606, IPR019087): ARC105 or Med15 subunit of Mediator complex non-fungal
56 MED16interactorWD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Med16 (PF11635, IPR021665): Mediator complex subunit 16
57 MED17oncoproteinMed17 (PF10156, IPR019313): Subunit 17 of Mediator complex
58 MED18interactorMed18 (PF09637, IPR019095): Med18 protein
59 MED19interactorMed19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
60 MED20parental proteinMed20 (PF08612, IPR013921): TATA-binding related factor (TRF) of subunit 20 of Mediator complex
61 MED21interactorMed21 (PF11221, IPR021384): Subunit 21 of Mediator complex
62 MED22interactorMed22 (PF06179, IPR009332): Surfeit locus protein 5 subunit 22 of Mediator complex
63 MED23interactorMed23 (PF11573, IPR021629): Mediator complex subunit 23
64 MED24interactorMed24_N (PF11277, IPR021429): Mediator complex subunit 24 N-terminal
65 MED26interactorMed26 (PF08711, IPR017923): TFIIS helical bundle-like domain
Med26_C (PF15693, IPR031416): Mediator complex subunit 26 C-terminal
Med26_M (PF15694, IPR031417): Mediator complex subunit 26 middle domain
66 MED27interactorMed27 (PF11571, IPR021627): Mediator complex subunit 27
67 MED28interactorcwf21 (PF08312, IPR013170, SM01115): cwf21 domain
Med28 (PF11594, IPR021640): Mediator complex subunit 28
68 MED29interactorMed29 (PF11568, IPR021018): Mediator complex subunit 29
69 MED30interactorMed30 (PF11315, IPR021019): Mediator complex subunit 30
70 MED4interactorMed4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
71 MED6interactorMed6 (PF04934, IPR007018): MED6 mediator sub complex component
Peptidase_M15 (PF01427, IPR000755): D-ala-D-ala dipeptidase
72 MED7interactorMed7 (PF05983, IPR009244): MED7 protein
DotU (PF09850, IPR017732): Type VI secretion system protein DotU
73 MED8interactorMed8 (PF10232, IPR019364): Mediator of RNA polymerase II transcription complex subunit 8
74 MED9interactorMed9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
75 MYH14interactorIQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
76 NCAPGinteractorP16-Arc (PF04699, IPR006789): ARP2/3 complex 16 kDa subunit (p16-Arc)
Terminase_2 (PF03592, IPR005335): Terminase small subunit
UVR (PF02151, IPR001943): UvrB/uvrC motif
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Cnd3 (PF12719, IPR025977): Nuclear condensing complex subunits, C-term domain
HEAT_2 (PF13646): HEAT repeats
77 NCBP1interactorMIF4G (PF02854, IPR003890, SM00543): MIF4G domain
MIF4G_like (PF09088, IPR015172): MIF4G like
MIF4G_like_2 (PF09090, IPR015174): MIF4G like
SlyX (PF04102, IPR007236): SlyX
78 NPEPPSinteractorPeptidase_M1 (PF01433, IPR014782): Peptidase family M1
ERAP1_C (PF11838, IPR024571): ERAP1-like C-terminal domain
79 PDCD6oncoproteinEF-hand_7 (PF13499, IPR011992): EF-hand domain pair
80 PDIA6interactorFAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
81 PHBsuppressorBand_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290)
82 PHB2interactorDUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605)
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
83 PI4KAinteractorPI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain)
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
Ipi1_N (PF12333, IPR024679): Rix1 complex component involved in 60S ribosome maturation
Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
84 POLR1BinteractorRNA_pol_Rpa2_4 (PF06883, IPR009674): RNA polymerase I, Rpa2 specific domain
RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
85 POLR2AinteractorRNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
86 PPA1interactorPyrophosphatase (PF00719, IPR008162): Inorganic pyrophosphatase
87 PPARGC1AinteractorPap_E4 (PF02711, IPR003861): E4 protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RSRP (PF17069): Arginine/Serine-Rich protein 1
88 PSMD10interactorAnk_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
89 QPCTinteractorPeptidase_M28 (PF04389, IPR007484): Peptidase family M28
90 RAB10oncoproteinRas (PF00071, IPR001806, SM00173): Ras family
91 RAD23AoncoproteinUBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
92 RAD23BsuppressorK_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
93 RECQLoncoproteinDEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Lipoprotein_3 (PF00938, IPR001595): Lipoprotein
RQC (PF09382, IPR018982, SM00956): RQC domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
94 RHOAsuppressorRas (PF00071, IPR001806, SM00173): Ras family
95 RIOK1interactorRIO1 (PF01163, IPR018934): RIO1 family
96 RPS10interactorS10_plectin (PF03501, IPR005326): Plectin/S10 domain
97 RRP1interactorNop52 (PF05997, IPR010301): Nucleolar protein,Nop52
Tn7_Tnp_TnsA_C (PF08721, IPR014832): TnsA endonuclease C terminal
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
98 RSRC2interactorPap_E4 (PF02711, IPR003861): E4 protein
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
SMAP (PF15477, IPR028124): Small acidic protein family
99 SCP2interactorSCP2 (PF02036, IPR003033): SCP-2 sterol transfer family
Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
100 SERPINH1interactorSerpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
101 SLTMinteractorDUF1980 (PF09323, IPR015402): Domain of unknown function (DUF1980)
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Podoplanin (PF05808, IPR008783): Podoplanin
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAP (PF02037, IPR003034, SM00513): SAP domain
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
102 SNRPGinteractorLSM (PF01423, IPR001163): LSM domain
103 SPG20interactorMIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
Senescence (PF06911, IPR009686): Senescence-associated protein
104 SPTAN1oncoproteinEFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Tetrabrachion (PF11401, IPR021535): Tetrabrachion
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
105 SRSF5interactorDUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
106 SUGT1interactorCheC (PF04509, IPR007597): CheC-like family
CS (PF04969, IPR007052): CS domain
SGS (PF05002, IPR007699): SGS domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
107 SUMO4interactorSRP9-21 (PF05486): Signal recognition particle 9 kDa protein (SRP9)
Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
108 TADA2AinteractorSWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
109 TCEA1oncoproteinMed26 (PF08711, IPR017923): TFIIS helical bundle-like domain
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
110 TCL1BoncoproteinTCL1_MTCP1 (PF01840, IPR004832): TCL1/MTCP1 family
111 THOC2interactorSec62 (PF03839, IPR004728): Translocation protein Sec62
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
Thoc2 (PF11732, IPR021726): Transcription- and export-related complex subunit
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
THOC2_N (PF16134, IPR032302): THO complex subunit 2 N-terminus
112 TMED2interactorEMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD
113 TPD52L2interactorTPD52 (PF04201, IPR007327): Tumour protein D52 family
114 TPI1interactorTIM (PF00121, IPR000652): Triosephosphate isomerase
115 TRA2BinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
116 TRAPPC5interactorTRAPP (PF04051, IPR007194): Transport protein particle (TRAPP) component
117 TRIM25interactorFes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
118 UBBinteractorubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
119 VDAC1interactorPorin_3 (PF01459, IPR027246): Eukaryotic porin
120 WASF1interactorMito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
WH2 (PF02205, IPR003124, SM00246): WH2 motif
121 ZC3H13interactorFGF-BP1 (PF06473, IPR010510): FGF binding protein 1 (FGF-BP1)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
PET117 (PF15786, IPR031568): PET assembly of cytochrome c oxidase, mitochondrial

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