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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: AI018497 is the fusion of parental proteins TCF3, SCCPDH (from a repository: Tue Dec 6 06:31:40 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)48
The number (and %) of the onco-proteins14 (29.17 %)
The number (and %) of the tumor suppressors5 (10.42 %)
Total number of binary PPIs (saturation %)104 (9.22 %)
The number (and %) of affected PPIs47 (45.19 %)
The number of possible different fusions6
PPI diameter2
PPI radius1
The average degree of PPI3.750
Assortativity coefficient-0.2373
The network average Clustering coefficient0.606
The number (and %) of a zero Clustering coefficients11 (22.92 %)
The number (and %) of a zero Betweenness Centrality32 (66.67 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: TCF3,SCCPDH All fusions
: AI018497;
Proteins found in more fusions KDM1A (see 2 fusions); RCOR1 (see 2 fusions); TRIM33 (see 1 fusions); SQSTM1 (see 5 fusions); SLC9A3R1 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AI018497chimera470.0401921.833Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family
Sacchrp_dh_NADP (PF03435, IPR005097): Saccharopine dehydrogenase NADP binding domain
2 ASB2interactor31.0000Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
3 BZW1interactor21.0000W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
4 CALM1interactor21.0000EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
5 COQ9interactor40.6670.667COQ9 (PF08511, IPR013718): COQ9
6 DAXXoncoprotein31.0000Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Nop14 (PF04147, IPR007276): Nop14-like family
RF-1 (PF00472, IPR000352): RF-1 domain
Vpu (PF00558, IPR008187): Vpu protein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
7 DDB2suppressor200WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
8 DNAJB11interactor30.6670.500DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
9 DNAJC10interactor21.0000DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
10 EEF1A2oncoprotein100GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
11 ERAL1interactor30.6670.667GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
KH_1 (PF00013, IPR004088, SM00322): KH domain
12 FAM63Binteractor100DUF544 (PF04424, IPR007518): Protein of unknown function (DUF544)
Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor
CCDC50_N (PF15295, IPR029311): Coiled-coil domain-containing protein 50 N-terminus
13 GLRXinteractor21.0000Glutaredoxin (PF00462, IPR002109): Glutaredoxin
14 HAUS7interactor21.0000M3 (PF09213, IPR015296): M3
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
15 HECTD3interactor30.6671.000ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
16 KBTBD7interactor21.0000BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_2 (PF07646, IPR011498): Kelch motif
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_4 (PF13418): Galactose oxidase, central domain
Kelch_6 (PF13964): Kelch motif
17 KDM1Aprotein found in more fusions50.5003.000Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
18 LMX1Ainteractor200LIM (PF00412, IPR001781, SM00132): LIM domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
19 MDH1interactor50.6003.667Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
20 MIEN1interactor100Rdx (PF10262, IPR011893): Rdx family
21 NDUFA4interactor50.5002.667B12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
22 NDUFB4interactor21.0000NDUF_B4 (PF07225, IPR009866): NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
23 NTRK1oncoprotein170.17597.000I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
24 PAIP2suppressor21.0000PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
25 PAXIP1interactor50.4005.000BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase
SURF6 (PF04935, IPR007019): Surfeit locus protein 6
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
26 PDE4DIPoncoprotein21.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1220 (PF06758, IPR010630, SM01148): Repeat of unknown function (DUF1220)
DUF1515 (PF07439, IPR010889): Protein of unknown function (DUF1515)
IncA (PF04156, IPR007285): IncA protein
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
Nup54 (PF13874, IPR025712): Nucleoporin complex subunit 54
FAM76 (PF16046, IPR032017): FAM76 protein
MPS2 (PF17060, IPR031433): Monopolar spindle protein 2
27 PEX19interactor21.0000Pex19 (PF04614, IPR006708): Pex19 protein family
Rod-binding (PF10135, IPR019301): Rod binding protein
28 PGM1interactor40.6671.500PGM_PMM_I (PF02878, IPR005844): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
PGM_PMM_II (PF02879, IPR005845): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
PGM_PMM_III (PF02880, IPR005846): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
PGM_PMM_IV (PF00408, IPR005843): Phosphoglucomutase/phosphomannomutase, C-terminal domain
29 PSMD4interactor31.0000UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
30 RAB4Aoncoprotein100Ras (PF00071, IPR001806, SM00173): Ras family
31 RCOR1protein found in more fusions31.0000DivIC (PF04977, IPR007060): Septum formation initiator
ELM2 (PF01448, IPR000949): ELM2 domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
FAM76 (PF16046, IPR032017): FAM76 protein
32 RPN1oncoprotein31.0000Ribophorin_I (PF04597, IPR007676): Ribophorin I
CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
33 SKP2suppressor40.5003.000LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_2 (PF07723, IPR013101): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
34 SLC39A4suppressor100Zip (PF02535, IPR003689): ZIP Zinc transporter
Class_IIIsignal (PF04021, IPR007166): Class III signal peptide
35 SLC9A3R1suppressor50.6672.000EBP50_C (PF09007, IPR015098): EBP50, C-terminal
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
36 SONinteractor100Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
G-patch (PF01585, IPR000467, SM00443): G-patch domain
tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1
GREB1 (PF15782, IPR028422): Gene regulated by oestrogen in breast cancer
RSRP (PF17069): Arginine/Serine-Rich protein 1
37 SQSTM1oncoprotein60.6003.667PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
UBA_5 (PF16577, IPR015940): UBA domain
38 TADA2Ainteractor21.0000SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
39 TAF1oncoprotein100Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
LcrG (PF07216, IPR009863): LcrG protein
Opi1 (PF08618, IPR013927): Transcription factor Opi1
Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal
TBP-binding (PF09247, IPR009067): TATA box-binding protein binding
U3_snoRNA_assoc (PF08297, IPR013268): U3 snoRNA associated
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3591 (PF12157, IPR022591): Protein of unknown function (DUF3591)
zf-CCHC_6 (PF15288): Zinc knuckle
40 TLE1interactor200TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
41 TMEM160interactor21.0000Borrelia_P13 (PF05628, IPR008420): Borrelia membrane protein P13
DUF202 (PF02656, IPR003807): Domain of unknown function (DUF202)
42 TRIM33oncoprotein41.0000PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Siva (PF05458, IPR022773): Cd27 binding protein (Siva)
Spectrin (PF00435, IPR002017): Spectrin repeat
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
43 TWIST1oncoprotein100ACC_epsilon (PF13822, IPR032716): Acyl-CoA carboxylase epsilon subunit
PRR20 (PF15708, IPR031439): Proline-rich protein family 20
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
44 UQCRC2oncoprotein50.5004.667Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
45 USP13interactor21.0000UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
46 WAPLinteractor31.0000WAPL (PF07814, IPR022771): Wings apart-like protein regulation of heterochromatin
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
47 XPO1interactor90.27825.167CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
48 ZZEF1interactor21.0000ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
CUB (PF00431, IPR000859, SM00042): CUB domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 ACTR1BinteractorActin (PF00022, IPR004000, SM00268): Actin
2 ALDH18A1interactorAA_kinase (PF00696, IPR001048): Amino acid kinase family
Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family
3 ATOH8interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
4 ATP2A3interactorCation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
5 BCORoncoproteinAnk_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
BCOR (PF15808, IPR031628): BCL-6 co-repressor, non-ankyrin-repeat region
PUFD (PF16553, IPR032365): BCORL-PCGF1-binding domain
6 BHLHA15interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
7 BHLHE40interactorHairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
8 C14orf166interactorRLL (PF10036, IPR019265): Putative carnitine deficiency-associated protein
9 C1QBPinteractorMAM33 (PF02330, IPR003428): Mitochondrial glycoprotein
DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
10 CANXinteractorCalreticulin (PF00262, IPR001580): Calreticulin family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
11 CASP14interactorPeptidase_C14 (PF00656, IPR011600): Caspase domain
12 CBFA2T3suppressorNHR2 (PF08788, IPR014896): NHR2 domain like
TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF
zf-MYND (PF01753, IPR002893): MYND finger
Efg1 (PF10153, IPR019310): rRNA-processing protein Efg1
PRIMA1 (PF16101): Proline-rich membrane anchor 1
13 CCT2interactorCpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
14 CHCHD3interactorDUF737 (PF05300, IPR007964): Protein of unknown function (DUF737)
eIF3g (PF12353, IPR024675): Eukaryotic translation initiation factor 3 subunit G
15 COX7A2interactorCOX7a (PF02238, IPR003177): Cytochrome c oxidase subunit VII
16 CPDinteractorPeptidase_M14 (PF00246, IPR000834, SM00631): Zinc carboxypeptidase
CarboxypepD_reg (PF13620): Carboxypeptidase regulatory-like domain
17 CPT2interactorCarn_acyltransf (PF00755, IPR000542): Choline/Carnitine o-acyltransferase
18 CREBBPsuppressorCreb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
19 CSTAoncoproteinCystatin (PF00031, IPR000010, SM00043): Cystatin domain
20 DDX17interactorCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Ferritin (PF00210, IPR008331): Ferritin-like domain
GRP (PF07172, IPR010800): Glycine rich protein family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
21 DDX20interactorDEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
22 DNMT1suppressorBAH (PF01426, IPR001025, SM00439): BAH domain
DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain
DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
23 EIF5AinteractorEFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain
eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
24 ELAVL1oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
25 ELK3oncoproteinEts (PF00178, IPR000418, SM00413): Ets-domain
Translat_reg (PF01818, IPR002702): Bacteriophage translational regulator
26 EP300oncoproteinCreb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
27 ERLIN2interactorBand_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
28 FBLinteractorFibrillarin (PF01269, IPR000692): Fibrillarin
29 FLG2interactorS_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
AP3D1 (PF06375): AP-3 complex subunit delta-1
30 FOXH1interactorForkhead (PF00250, IPR001766, SM00339): Forkhead domain
31 GSE1oncoproteinCENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
Plasmodium_Vir (PF05795, IPR008780): Plasmodium vivax Vir protein
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
DUF3736 (PF12540, IPR022207): Protein of unknown function (DUF3736)
AAA_11 (PF13086): AAA domain
DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
32 HAND1interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
33 HAND2interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
34 HDAC2suppressorHist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
35 HNRNPRinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
36 ID1interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
37 ID2oncoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
38 ID3oncoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
39 ID4suppressorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Lipase_3 (PF01764, IPR002921): Lipase (class 3)
40 IMMTinteractorMitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
41 INO80EinteractorNBP1 (PF08537, IPR013743): Fungal Nap binding protein NBP1
42 KAT2AinteractorAcetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
43 KAT2BinteractorAcetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
44 KIF18AinteractorKinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
DUF4005 (PF13178, IPR025064): Protein of unknown function (DUF4005)
45 LANCL2interactorGlyco_hydro_127 (PF07944, IPR012878): Beta-L-arabinofuranosidase, GH127
LANC_like (PF05147, IPR007822): Lanthionine synthetase C-like protein
46 LBRinteractorERG4_ERG24 (PF01222, IPR001171): Ergosterol biosynthesis ERG4/ERG24 family
LBR_tudor (PF09465, IPR019023): Lamin-B receptor of TUDOR domain
47 LDB1oncoproteinLIM_bind (PF01803): LIM-domain binding protein
48 LGALS7suppressorGal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
49 LYL1oncoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
50 MAPKAPK2oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
51 MAPKAPK3interactorPkinase (PF00069, IPR000719): Protein kinase domain
52 MEN1suppressorMenin (PF05053, IPR007747): Menin
53 MESP2interactorDUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
54 MRPL23interactorRibosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
55 MRPL37interactorPDCD9 (PF07147, IPR010793): Mitochondrial 28S ribosomal protein S30 (PDCD9)
56 MRPL39interactorTGS (PF02824, IPR004095): TGS domain
DUF2469 (PF10611, IPR019592): Protein of unknown function (DUF2469)
57 MRPL44interactordsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain
58 MRPL49interactorImg2 (PF05046, IPR007740): Mitochondrial large subunit ribosomal protein (Img2)
59 MYF5interactorAuxin_repressed (PF05564, IPR008406): Dormancy/auxin associated protein
Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myf5 (PF12232, IPR022032): Myogenic determination factor 5
60 MYF6interactorBasic (PF01586, IPR002546, SM00520): Myogenic Basic domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myf5 (PF12232, IPR022032): Myogenic determination factor 5
61 MYL6BinteractorSapB_1 (PF05184, IPR007856): Saposin-like type B, region 1
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
62 MYO1BinteractorIQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
RNA_pol (PF00940, IPR002092): DNA-dependent RNA polymerase
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
AAA_23 (PF13476): AAA domain
63 MYOD1oncoproteinBasic (PF01586, IPR002546, SM00520): Myogenic Basic domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Mfp-3 (PF04202, IPR007328): Foot protein 3
Myf5 (PF12232, IPR022032): Myogenic determination factor 5
64 MYOGinteractorBasic (PF01586, IPR002546, SM00520): Myogenic Basic domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
65 NEDD9interactorSerine_rich (PF08824, IPR014928): Serine rich protein interaction domain
DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
66 NEUROD1interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
Neuro_bHLH (PF12533, IPR022575): Neuronal helix-loop-helix transcription factor
67 NHLH1interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
68 NHLH2interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
69 PARP1suppressorBRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain
PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain
WGR (PF05406, IPR008893, SM00773): WGR domain
zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
70 PCBP1oncoproteinBac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein
KH_2 (PF07650, IPR004044): KH domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
71 PIPinteractorSVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA)
72 PON2interactorArylesterase (PF01731, IPR002640): Arylesterase
73 PRMT5interactorPRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
74 PRPF8oncoproteinPRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain
PROCN (PF08083, IPR012592): PROCN (NUC071) domain
PROCT (PF08084, IPR012984): PROCT (NUC072) domain
RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8
U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8
U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core
75 PTF1AinteractorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
76 RB1suppressorRB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
77 RBM39oncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
78 RNF14interactorIBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
RWD (PF05773, IPR006575, SM00591): RWD domain
T5orf172 (PF10544, IPR018306, SM00974): T5orf172 domain
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
zf-RING_11 (PF17123, IPR001841): RING-like zinc finger
79 RPL13interactorRibosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
80 RPL14interactorKOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
81 RPL23AinteractorRibosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain
82 RPL24interactorMAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
83 RPL31interactorRibosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e
84 RPL36AinteractorNOB1_Zn_bind (PF08772, IPR014881): Nin one binding (NOB1) Zn-ribbon like
Ribosomal_L44 (PF00935, IPR000552): Ribosomal protein L44
85 RPL37interactorRibosomal_L37e (PF01907, IPR001569): Ribosomal protein L37e
86 RPN2interactorRibophorin_II (PF05817, IPR008814): Oligosaccharyltransferase subunit Ribophorin II
87 RPS13interactorRibosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain
Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
88 RUNX1suppressorRunt (PF00853, IPR013524): Runt domain
RunxI (PF08504, IPR013711): Runx inhibition domain
DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
89 RUNX1T1oncoproteinNHR2 (PF08788, IPR014896): NHR2 domain like
TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF
zf-MYND (PF01753, IPR002893): MYND finger
DUF3731 (PF12531, IPR021030): DNA-K related protein
90 SAAL1interactorNA
91 SAFBsuppressorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAP (PF02037, IPR003034, SM00513): SAP domain
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
92 SCCPDHparental proteinSacchrp_dh_NADP (PF03435, IPR005097): Saccharopine dehydrogenase NADP binding domain
93 SCXinteractorCAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
94 SERPINH1interactorSerpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
95 SETSIPinteractorNAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
96 SF3A3interactorDUF3449 (PF11931, IPR024598): Domain of unknown function (DUF3449)
SF3a60_bindingd (PF12108, IPR021966): Splicing factor SF3a60 binding domain
Telomere_Sde2_2 (PF13297): Telomere stability C-terminal
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
SF3A3 (PF16837, IPR031774): Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9
97 SLC25A10interactorMito_carr (PF00153, IPR018108): Mitochondrial carrier protein
98 SLC25A4interactorMito_carr (PF00153, IPR018108): Mitochondrial carrier protein
99 SOX2oncoproteinHMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
100 SPIN1interactorSpin-Ssty (PF02513, IPR003671): Spin/Ssty Family
101 SSBP1interactorSSB (PF00436, IPR000424): Single-strand binding protein family
102 STK38interactorMEKHLA (PF08670, IPR013978): MEKHLA domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
103 SUPT3HinteractorTFIID-18kDa (PF02269, IPR003195): Transcription initiation factor IID, 18kD subunit
DUF4093 (PF13331, IPR025156): Domain of unknown function (DUF4093)
104 TAL1oncoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
105 TCAF1interactorPeptidase_M60 (PF13402, IPR031161): Peptidase M60, enhancin and enhancin-like
106 TCF12oncoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
107 TCF21interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
108 TCF24interactorHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
109 TCF3parental proteinCDC45 (PF02724, IPR003874): CDC45-like protein
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
110 TCF4suppressorCDC45 (PF02724, IPR003874): CDC45-like protein
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
111 TET2suppressorTet_JBP (PF12851, IPR024779): Oxygenase domain of the 2OGFeDO superfamily
112 TFF3oncoproteinTrefoil (PF00088, IPR000519, SM00018): Trefoil (P-type) domain
113 TIMM50interactorNIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
114 TRRAPinteractorBALF1 (PF06861, IPR010677): BALF1 protein
BP28CT (PF08146, IPR012954, SM01036): BP28CT (NUC211) domain
DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
CLASP_N (PF12348, IPR024395): CLASP N terminal
Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal
HEAT_EZ (PF13513): HEAT-like repeat
TRC8_N (PF13705, IPR025754): TRC8 N-terminal domain
ACDC (PF14733, IPR028078): AP2-coincident C-terminal
115 UBE2IinteractorUQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
116 USF1oncoproteinHLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
117 VDRsuppressorzf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
118 YY1interactorzf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail

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