1 |
AF362886 | chimera | 146 | 0.078 | 13517.509 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SlyX (PF04102, IPR007236): SlyX Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
2 |
ACTB | oncoprotein | 19 | 0.477 | 25.425 | Actin (PF00022, IPR004000, SM00268): Actin |
3 |
ACTN1 | protein found in more fusions | 26 | 0.460 | 71.446 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Dak2 (PF02734, IPR004007, SM01120): DAK2 domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair Uds1 (PF15456, IPR029191): Up-regulated During Septation |
4 |
ACTN2 | protein found in more fusions | 9 | 0.679 | 6.908 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Nsp1_C (PF05064, IPR007758): Nsp1-like C-terminal region Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
5 |
ACTN4 | interactor | 28 | 0.429 | 85.969 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair Uds1 (PF15456, IPR029191): Up-regulated During Septation |
6 |
ADD1 | interactor | 6 | 0.867 | 0.336 | Aldolase_II (PF00596, IPR001303, SM01007): Class II Aldolase and Adducin N-terminal domain CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal |
7 |
AHCYL1 | suppressor | 9 | 0.393 | 9.494 | AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF515 (PF04415, IPR007509): Protein of unknown function (DUF515) Big_3_5 (PF16640, IPR032109): Bacterial Ig-like domain (group 3) |
8 |
ANLN | oncoprotein | 16 | 0.700 | 13.626 | Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus |
9 |
ATP1A1 | protein found in more fusions | 11 | 0.382 | 15.171 | Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase Tetraspannin (PF00335, IPR018499): Tetraspanin family Cation_ATPase (PF13246): Cation transport ATPase (P-type) |
10 |
ATP5F1 | interactor | 11 | 0.418 | 13.660 | Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2105 (PF09878, IPR019212): Predicted membrane protein (DUF2105) |
11 |
BLOC1S6 | interactor | 5 | 0.500 | 3.000 | BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin |
12 |
BRCA1 | suppressor | 21 | 0.258 | 80.816 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
13 |
C1orf216 | interactor | 3 | 0.667 | 1.000 | DUF4653 (PF15546, IPR027812): Domain of unknown function (DUF4653) |
14 |
CAP1 | interactor | 11 | 0.733 | 3.311 | CAP_C (PF08603, IPR013912): Adenylate cyclase associated (CAP) C terminal CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator |
15 |
CAPZA2 | interactor | 26 | 0.489 | 58.218 | F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit |
16 |
CCDC102B | interactor | 6 | 0.700 | 2.000 | Filament (PF00038, IPR001664): Intermediate filament protein Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein Myosin_tail_1 (PF01576, IPR002928): Myosin tail PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
17 |
CCDC114 | interactor | 2 | 1.000 | 0 | FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) Histone_HNS (PF00816, IPR001801): H-NS histone family Hydantoinase_B (PF02538, IPR003692): Hydantoinase B/oxoprolinase DUF2353 (PF09789, IPR019179): Uncharacterized coiled-coil protein (DUF2353) PLAC9 (PF15205, IPR027941): Placenta-specific protein 9 |
18 |
CCDC146 | interactor | 4 | 0.500 | 3.000 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
19 |
CCHCR1 | interactor | 8 | 0.333 | 12.000 | HCR (PF07111, IPR009800): Alpha helical coiled-coil rod protein (HCR) |
20 |
CDC123 | interactor | 2 | 1.000 | 0 | D123 (PF07065, IPR009772): D123 |
21 |
CDK2 | suppressor | 37 | 0.295 | 192.781 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
22 |
CENPF | oncoprotein | 4 | 1.000 | 0 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like bZIP_1 (PF00170, IPR004827): bZIP transcription factor DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) ZapB (PF06005, IPR009252): Cell division protein ZapB DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Fez1 (PF06818): Fez1 Filament (PF00038, IPR001664): Intermediate filament protein HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7) IncA (PF04156, IPR007285): IncA protein Propep_M14 (PF02244, IPR003146): Carboxypeptidase activation peptide Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Usp (PF00582, IPR006016): Universal stress protein family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-F_N (PF10481, IPR018463): Cenp-F N-terminal domain CENP-F_C_Rb_bdg (PF10490, IPR018302): Rb-binding domain of kinetochore protein Cenp-F/LEK1 DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140) DUF4239 (PF14023, IPR025333): Protein of unknown function (DUF4239) TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor |
23 |
CKB | interactor | 13 | 0.487 | 13.495 | ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain |
24 |
CKMT1A | interactor | 3 | 0.667 | 0.500 | ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain |
25 |
CKMT1B | interactor | 4 | 0.667 | 0.682 | ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain |
26 |
CORO1C | oncoprotein | 20 | 0.526 | 25.179 | DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat WD40_4 (PF16300): Type of WD40 repeat |
27 |
COX4I1 | interactor | 7 | 0.571 | 7.000 | COX4 (PF02936, IPR004203): Cytochrome c oxidase subunit IV |
28 |
COX5A | interactor | 6 | 0.533 | 3.332 | COX5A (PF02284, IPR003204): Cytochrome c oxidase subunit Va |
29 |
CUL3 | protein found in more fusions | 32 | 0.183 | 230.893 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
30 |
CUL7 | protein found in more fusions | 28 | 0.234 | 122.763 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
31 |
CYC1 | interactor | 9 | 0.389 | 11.667 | Cytochrom_C1 (PF02167, IPR002326): Cytochrome C1 family |
32 |
DAPK1 | suppressor | 10 | 0.444 | 7.060 | ABC_tran (PF00005, IPR003439): ABC transporter Death (PF00531, IPR000488, SM00005): Death domain Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) AAA_23 (PF13476): AAA domain Ank_5 (PF13857): Ankyrin repeats (many copies) COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
33 |
DVL2 | interactor | 10 | 0.444 | 11.248 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled (PF02377, IPR003351): Dishevelled specific domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DIX (PF00778, IPR001158, SM00021): DIX domain Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal |
34 |
EGFR | oncoprotein | 30 | 0.308 | 150.776 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
35 |
EIF4A2 | oncoprotein | 6 | 0.500 | 2.956 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
36 |
ELAVL1 | oncoprotein | 33 | 0.220 | 247.147 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
37 |
EPHA1 | suppressor | 3 | 0.667 | 0.200 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain |
38 |
EPHB2 | suppressor | 4 | 1.000 | 0 | EGF_2 (PF07974, IPR013111): EGF-like domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain |
39 |
FAM9C | interactor | 1 | 0 | 0 | Cor1 (PF04803, IPR006888): Cor1/Xlr/Xmr conserved region DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) |
40 |
FASN | interactor | 16 | 0.476 | 19.853 | Acyl_transf_1 (PF00698, IPR014043): Acyl transferase domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ketoacyl-synt (PF00109, IPR014030): Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C (PF02801, IPR014031): Beta-ketoacyl synthase, C-terminal domain KR (PF08659, IPR013968, SM00130): KR domain L27 (PF02828, IPR014775, SM00569): L27 domain Methyltransf_12 (PF08242, IPR013217): Methyltransferase domain PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site Thioesterase (PF00975, IPR001031): Thioesterase domain YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase PS-DH (PF14765, IPR020807): Polyketide synthase dehydratase KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension |
41 |
FBXO5 | oncoprotein | 6 | 0.333 | 4.046 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain F-box (PF00646, IPR001810, SM00256): F-box domain |
42 |
FKBP4 | interactor | 11 | 0.655 | 5.596 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat |
43 |
FKBP5 | interactor | 11 | 0.491 | 15.991 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat NuDC (PF16273, IPR032572): Nuclear distribution C domain |
44 |
FLII | oncoprotein | 16 | 0.567 | 17.427 | Gelsolin (PF00626, IPR007123): Gelsolin repeat SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
45 |
FN1 | oncoprotein | 28 | 0.257 | 126.191 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
46 |
GAK | oncoprotein | 4 | 0.833 | 0.200 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein |
47 |
GRB2 | oncoprotein | 27 | 0.363 | 99.485 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
48 |
HDAC8 | interactor | 5 | 0.500 | 1.765 | DNase-RNase (PF02577, IPR003729): Bifunctional nuclease Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
49 |
HDDC3 | interactor | 1 | 0 | 0 | HD_4 (PF13328, IPR003607): HD domain |
50 |
HOOK2 | interactor | 4 | 0.667 | 0.182 | HOOK (PF05622, IPR008636): HOOK protein |
51 |
HSF2 | interactor | 2 | 1.000 | 0 | HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding HMMR_C (PF15908, IPR031794): Hyaluronan mediated motility receptor C-terminal |
52 |
HSP90AA1 | oncoprotein | 41 | 0.255 | 311.445 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
53 |
HSP90AB1 | oncoprotein | 35 | 0.312 | 165.888 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
54 |
HSPB1 | oncoprotein | 22 | 0.324 | 91.081 | HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
55 |
HSPD1 | suppressor | 20 | 0.358 | 49.037 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
56 |
IFIT3 | interactor | 3 | 1.000 | 0 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
57 |
IKBIP | interactor | 2 | 1.000 | 0 | Fez1 (PF06818): Fez1 Occludin_ELL (PF07303, IPR010844): Occludin homology domain GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) SesA (PF17107, IPR031352): N-terminal domain on NACHT_NTPase and P-loop NTPases |
58 |
IKBKG | interactor | 19 | 0.268 | 70.202 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
59 |
IQGAP1 | interactor | 36 | 0.368 | 157.945 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain |
60 |
IRS1 | interactor | 8 | 0.643 | 6.400 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain |
61 |
JAK2 | oncoprotein | 17 | 0.483 | 27.262 | FERM_M (PF00373, IPR019748): FERM central domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
62 |
JAK3 | oncoprotein | 7 | 0.429 | 8.300 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
63 |
KCNE1 | interactor | 1 | 0 | 0 | ISK_Channel (PF02060, IPR000369): Slow voltage-gated potassium channel |
64 |
KIFC3 | oncoprotein | 5 | 0.833 | 0.667 | Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein KxDL (PF10241, IPR019371): Uncharacterized conserved protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
65 |
KRT18 | interactor | 13 | 0.303 | 26.610 | Filament (PF00038, IPR001664): Intermediate filament protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein |
66 |
KXD1 | interactor | 2 | 1.000 | 0 | KxDL (PF10241, IPR019371): Uncharacterized conserved protein |
67 |
KYNU | interactor | 3 | 0.667 | 1.000 | Aminotran_5 (PF00266, IPR000192): Aminotransferase class-V CaKB (PF03185, IPR003930): Calcium-activated potassium channel, beta subunit |
68 |
LCA5L | interactor | 1 | 0 | 0 | DUF1515 (PF07439, IPR010889): Protein of unknown function (DUF1515) Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain |
69 |
LRRK2 | oncoprotein | 14 | 0.397 | 20.078 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043) T2SSE (PF00437, IPR001482): Type II/IV secretion system protein Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) PQQ_2 (PF13360, IPR002372): PQQ-like domain LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
70 |
LURAP1 | interactor | 2 | 1.000 | 0 | LURAP (PF14854): Leucine rich adaptor protein DUF4530 (PF15039, IPR029202): Domain of unknown function (DUF4530) |
71 |
MAD1L1 | suppressor | 5 | 0.500 | 1.487 | MAD (PF05557, IPR008672): Mitotic checkpoint protein Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 |
72 |
MAGEA11 | interactor | 6 | 0.400 | 5.333 | MAGE (PF01454, IPR002190): MAGE family MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
73 |
MAGED2 | interactor | 13 | 0.500 | 18.915 | CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 MAGE (PF01454, IPR002190): MAGE family SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) |
74 |
MAP2K7 | interactor | 7 | 0.429 | 5.166 | Pkinase (PF00069, IPR000719): Protein kinase domain |
75 |
MAP3K1 | oncoprotein | 14 | 0.359 | 26.039 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Pkinase (PF00069, IPR000719): Protein kinase domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal |
76 |
MAPK1 | oncoprotein | 18 | 0.301 | 45.251 | Pkinase (PF00069, IPR000719): Protein kinase domain |
77 |
MAPK8IP3 | interactor | 5 | 0.700 | 1.400 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449 JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
78 |
MCC | suppressor | 4 | 0.500 | 2.500 | ERM (PF00769, IPR011259): Ezrin/radixin/moesin family IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein MCC-bdg_PDZ (PF10506, IPR019536): PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding EF-hand_7 (PF13499, IPR011992): EF-hand domain pair FAM76 (PF16046, IPR032017): FAM76 protein |
79 |
MCM2 | oncoprotein | 31 | 0.361 | 111.911 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
80 |
MCM3 | interactor | 13 | 0.526 | 10.521 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
81 |
MDC1 | suppressor | 10 | 0.556 | 10.597 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
82 |
MGEA5 | oncoprotein | 11 | 0.509 | 14.794 | NAGidase (PF07555, IPR011496): beta-N-acetylglucosaminidase |
83 |
MOV10 | interactor | 16 | 0.233 | 55.895 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
84 |
MTCH1 | interactor | 4 | 0.500 | 0.952 | YdjM (PF04307, IPR007404): LexA-binding, inner membrane-associated putative hydrolase Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
85 |
MYBPC2 | interactor | 1 | 0 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain |
86 |
MYH10 | interactor | 12 | 0.470 | 14.667 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
87 |
MYH7B | interactor | 7 | 0.714 | 2.650 | Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail YkuI_C (PF10388, IPR018842): EAL-domain associated signalling protein domain Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
88 |
MYH9 | suppressor | 31 | 0.501 | 62.397 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
89 |
MYO18A | interactor | 22 | 0.532 | 38.323 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_tail_1 (PF01576, IPR002928): Myosin tail PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
90 |
MYO19 | interactor | 19 | 0.649 | 13.714 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
91 |
MYO5C | interactor | 16 | 0.650 | 12.283 | DIL (PF01843, IPR018444, SM01132): DIL domain DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Pilus_CpaD (PF09476, IPR019027): Pilus biogenesis CpaD protein (pilus_cpaD) Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) YtxH (PF12732, IPR024623): YtxH-like protein Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
92 |
MYO6 | protein found in more fusions | 18 | 0.449 | 29.760 | BUD22 (PF09073, IPR015158): BUD22 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Rad9 (PF04139, IPR007268): Rad9 Sec62 (PF03839, IPR004728): Translocation protein Sec62 XhlA (PF10779, IPR019715): Haemolysin XhlA Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887) Myosin-VI_CBD (PF16521, IPR032412): Myosin VI cargo binding domain |
93 |
NDUFB10 | interactor | 5 | 0.700 | 1.083 | NDUFB10 (PF10249, IPR019377): NADH-ubiquinone oxidoreductase subunit 10 |
94 |
NEK2 | interactor | 7 | 0.467 | 6.786 | Pkinase (PF00069, IPR000719): Protein kinase domain |
95 |
NTRK1 | oncoprotein | 60 | 0.167 | 934.454 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
96 |
NXF1 | interactor | 19 | 0.268 | 61.826 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
97 |
OBSL1 | protein found in more fusions | 30 | 0.268 | 140.180 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
98 |
OIP5 | interactor | 3 | 0.667 | 0.500 | Yippee-Mis18 (PF03226, IPR004910): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly |
99 |
OSTF1 | interactor | 5 | 0.500 | 1.305 | SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
100 |
PAN2 | interactor | 22 | 0.377 | 53.439 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
101 |
PARK2 | suppressor | 20 | 0.263 | 56.028 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
102 |
PAXIP1 | interactor | 7 | 0.524 | 4.971 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase SURF6 (PF04935, IPR007019): Surfeit locus protein 6 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
103 |
PBX3 | interactor | 1 | 0 | 0 | Homeobox_KN (PF05920, IPR008422): Homeobox KN domain PBC (PF03792, IPR005542): PBC domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
104 |
PDLIM3 | interactor | 2 | 1.000 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
105 |
PDLIM7 | interactor | 15 | 0.581 | 17.756 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
106 |
PIK3R1 | oncoprotein | 13 | 0.576 | 10.218 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
107 |
PLCG1 | oncoprotein | 11 | 0.509 | 12.797 | C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain SH2 (PF00017, IPR000980, SM00252): SH2 domain PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain PH_12 (PF16457, IPR001849): Pleckstrin homology domain |
108 |
PPP1CB | interactor | 24 | 0.580 | 31.521 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
109 |
PPP1CC | oncoprotein | 20 | 0.384 | 61.531 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
110 |
PRDX1 | oncoprotein | 12 | 0.400 | 5.750 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
111 |
PRKCQ | interactor | 4 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
112 |
PSMA2 | interactor | 7 | 0.733 | 0.697 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
113 |
PSMA6 | interactor | 12 | 0.379 | 17.899 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
114 |
RAB35 | oncoprotein | 2 | 1.000 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
115 |
RACK1 | suppressor | 17 | 0.333 | 37.549 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
116 |
RAD21 | oncoprotein | 11 | 0.527 | 9.637 | Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
117 |
RNF2 | interactor | 14 | 0.269 | 29.511 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
118 |
SEC23IP | interactor | 3 | 0.667 | 1.000 | DDHD (PF02862, IPR004177, SM01127): DDHD domain SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) WWE (PF02825, IPR004170, SM00678): WWE domain |
119 |
SEPT9 | oncoprotein | 7 | 0.429 | 4.255 | Septin (PF00735, IPR000038): Septin DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) |
120 |
SF3A2 | interactor | 8 | 0.679 | 2.645 | Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like Totivirus_coat (PF05518, IPR008871): Totivirus coat protein zf-met (PF12874): Zinc-finger of C2H2 type ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) |
121 |
SHC1 | oncoprotein | 22 | 0.376 | 46.491 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
122 |
SHC3 | interactor | 3 | 1.000 | 0 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
123 |
SHMT2 | interactor | 10 | 0.311 | 13.660 | SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase |
124 |
SMC6 | interactor | 3 | 1.000 | 0 | SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain |
125 |
SOCS1 | suppressor | 7 | 0.810 | 1.293 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box |
126 |
SP1 | protein found in more fusions | 17 | 0.425 | 33.517 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
127 |
SRC | oncoprotein | 19 | 0.333 | 63.491 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
128 |
STAT3 | suppressor | 16 | 0.352 | 34.235 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
129 |
STMN1 | interactor | 7 | 0.429 | 4.624 | Stathmin (PF00836, IPR000956): Stathmin family |
130 |
SYCE1 | interactor | 5 | 0.500 | 3.952 | CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit SYCE1 (PF15233, IPR026676): Synaptonemal complex central element protein 1 |
131 |
TBCD | interactor | 5 | 0.700 | 0.908 | HEAT (PF02985, IPR000357): HEAT repeat HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal HEAT_EZ (PF13513): HEAT-like repeat |
132 |
TFPT | oncoprotein | 3 | 1.000 | 0 | GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor |
133 |
THAP1 | interactor | 4 | 1.000 | 0 | THAP (PF05485, IPR006612, SM00980): THAP domain Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2 Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57 |
134 |
THOC1 | protein found in more fusions | 5 | 0.500 | 0.801 | Death (PF00531, IPR000488, SM00005): Death domain efThoc1 (PF11957, IPR021861): THO complex subunit 1 transcription elongation factor |
135 |
TLK1 | protein found in more fusions | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Vir_act_alpha_C (PF10400, IPR018309): Virulence activator alpha C-term |
136 |
TNNT1 | protein found in more fusions | 4 | 0.667 | 0.154 | Troponin (PF00992, IPR001978): Troponin DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050) |
137 |
TP53 | suppressor | 36 | 0.255 | 236.343 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
138 |
TP73 | suppressor | 6 | 0.900 | 0.200 | P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
139 |
TPM1 | protein found in more fusions | 41 | 0.221 | 412.050 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
140 |
TPM2 | protein found in more fusions | 28 | 0.362 | 134.157 | DASH_Spc19 (PF08287, IPR013251): Spc19 Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
141 |
TPM4 | oncoprotein | 39 | 0.273 | 304.125 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
142 |
TRAP1 | oncoprotein | 12 | 0.424 | 13.790 | HSP90 (PF00183, IPR001404): Hsp90 protein HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
143 |
TRIM27 | oncoprotein | 9 | 0.357 | 15.876 | IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
144 |
TRIP6 | interactor | 8 | 0.357 | 11.438 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region LIM (PF00412, IPR001781, SM00132): LIM domain |
145 |
TUBB4B | interactor | 19 | 0.427 | 24.773 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
146 |
UQCRC2 | oncoprotein | 8 | 0.571 | 6.003 | Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain |
147 |
VPS52 | interactor | 4 | 0.667 | 1.000 | Vps52 (PF04129, IPR007258): Vps52 / Sac2 family COG5 (PF10392, IPR019465): Golgi transport complex subunit 5 Sec3_C (PF09763, IPR019160): Exocyst complex component Sec3 |