1 |
AF297748 | chimera | 124 | 0.085 | 9803.088 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 GATase (PF00117, IPR017926): Glutamine amidotransferase class-I GMP_synt_C (PF00958, IPR001674): GMP synthase C terminal domain NAD_synthase (PF02540, IPR022310): NAD synthase Plasmodium_Vir (PF05795, IPR008780): Plasmodium vivax Vir protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) |
2 |
AFDN | oncoprotein | 7 | 0.429 | 5.771 | DIL (PF01843, IPR018444, SM01132): DIL domain DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) FHA (PF00498, IPR000253, SM00240): FHA domain MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family MAS20 (PF02064, IPR002056): MAS20 protein import receptor Pap_E4 (PF02711, IPR003861): E4 protein PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain ARGLU (PF15346): Arginine and glutamate-rich 1 |
3 |
AFF1 | oncoprotein | 11 | 0.600 | 9.533 | AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein |
4 |
AFF4 | oncoprotein | 9 | 0.694 | 5.486 | AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein |
5 |
AGO2 | interactor | 6 | 0.667 | 1.673 | ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Piwi (PF02171, IPR003165, SM00950): Piwi domain ArgoN (PF16486, IPR032474): N-terminal domain of argonaute ArgoMid (PF16487, IPR032473): Mid domain of argonaute ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain |
6 |
AGPAT2 | interactor | 1 | 0 | 0 | Acyltransferase (PF01553, IPR002123, SM00563): Acyltransferase DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131) |
7 |
AHCY | interactor | 9 | 0.536 | 7.140 | AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain |
8 |
APRT | interactor | 5 | 0.600 | 2.500 | Pribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain |
9 |
ASB2 | interactor | 7 | 0.467 | 6.833 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box |
10 |
AVP | interactor | 2 | 0 | 0 | Protamine_P1 (PF00260, IPR000221): Protamine P1 |
11 |
BABAM1 | interactor | 3 | 0.667 | 0.250 | VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain |
12 |
BMI1 | oncoprotein | 23 | 0.342 | 84.795 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
13 |
CBX4 | oncoprotein | 11 | 0.444 | 13.521 | Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region CBX7_C (PF17218): CBX family C-terminal motif |
14 |
CBX8 | interactor | 11 | 0.600 | 9.186 | Atrophin-1 (PF03154, IPR002951): Atrophin-1 family Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain RBR (PF17208): RNA binding Region CBX7_C (PF17218): CBX family C-terminal motif |
15 |
CCNT1 | oncoprotein | 13 | 0.515 | 16.994 | Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit MDFI (PF15316, IPR026134): MyoD family inhibitor |
16 |
CDC5L | interactor | 21 | 0.321 | 66.113 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
17 |
CDC73 | suppressor | 15 | 0.438 | 34.081 | CDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal |
18 |
CDK9 | protein found in more fusions | 17 | 0.433 | 39.664 | Pkinase (PF00069, IPR000719): Protein kinase domain |
19 |
CHD3 | oncoprotein | 21 | 0.474 | 42.358 | CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956) FAM176 (PF14851): FAM176 family |
20 |
COASY | interactor | 5 | 0.700 | 1.667 | CoaE (PF01121, IPR001977): Dephospho-CoA kinase CTP_transf_like (PF01467, IPR004821): Cytidylyltransferase-like |
21 |
CREBBP | suppressor | 24 | 0.368 | 75.879 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
22 |
CRY1 | interactor | 4 | 0.667 | 0.400 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
23 |
CSNK2A2 | interactor | 12 | 0.409 | 15.323 | Pkinase (PF00069, IPR000719): Protein kinase domain |
24 |
CTBP1 | protein found in more fusions | 14 | 0.500 | 14.726 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D |
25 |
CTNNB1 | oncoprotein | 11 | 0.473 | 11.308 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
26 |
CTPS1 | interactor | 8 | 0.667 | 2.406 | CTP_synth_N (PF06418, IPR017456): CTP synthase N-terminus GATase (PF00117, IPR017926): Glutamine amidotransferase class-I |
27 |
CTR9 | interactor | 16 | 0.383 | 49.938 | DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702) Pap_E4 (PF02711, IPR003861): E4 protein SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68) TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175) TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
28 |
CUL3 | protein found in more fusions | 30 | 0.197 | 216.632 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
29 |
CXXC1 | interactor | 8 | 0.571 | 5.323 | ATP-synt_E (PF05680, IPR008386): ATP synthase E chain PHD (PF00628, IPR019787, SM00249): PHD-finger PLATZ (PF04640, IPR006734): PLATZ transcription factor zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain DUF2116 (PF09889, IPR019216): Uncharacterized protein containing a Zn-ribbon (DUF2116) Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 DUF3347 (PF11827, IPR021782): Protein of unknown function (DUF3347) zf-CpG_bind_C (PF12269, IPR022056): CpG binding protein zinc finger C terminal domain |
30 |
DDA1 | interactor | 2 | 1.000 | 0 | DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase |
31 |
DDX5 | oncoprotein | 23 | 0.325 | 72.771 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
32 |
DOT1L | oncoprotein | 7 | 0.524 | 5.300 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif DivIC (PF04977, IPR007060): Septum formation initiator DOT1 (PF08123, IPR013110): Histone methylation protein DOT1 ZapB (PF06005, IPR009252): Cell division protein ZapB HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper TraV (PF09676, IPR014118): Type IV conjugative transfer system lipoprotein (TraV) |
33 |
DYNLT1 | interactor | 4 | 0.667 | 1.667 | Tctex-1 (PF03645, IPR005334): Tctex-1 family |
34 |
E2F2 | suppressor | 1 | 0 | 0 | E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
35 |
E2F4 | suppressor | 4 | 1.000 | 0 | E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain Pheromone (PF08015, IPR012597): Fungal mating-type pheromone SPX (PF03105, IPR004331): SPX domain DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584) E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
36 |
E2F6 | oncoprotein | 6 | 0.800 | 1.033 | BRCA-2_OB3 (PF09104, IPR015188): BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
37 |
EFHD2 | interactor | 6 | 0.600 | 5.000 | SPARC_Ca_bdg (PF10591, IPR019577): Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
38 |
ELL | oncoprotein | 8 | 0.571 | 5.457 | Occludin_ELL (PF07303, IPR010844): Occludin homology domain ELL (PF10390, IPR019464): RNA polymerase II elongation factor ELL |
39 |
ENO2 | interactor | 8 | 0.429 | 13.500 | Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain |
40 |
EWSR1 | oncoprotein | 22 | 0.314 | 77.304 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
41 |
FBXO6 | interactor | 10 | 0.244 | 21.486 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
42 |
FN1 | oncoprotein | 20 | 0.253 | 77.230 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
43 |
GLO1 | interactor | 4 | 0.500 | 0.933 | Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily |
44 |
H3F3A | oncoprotein | 13 | 0.359 | 29.976 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
45 |
HCFC1 | protein found in more fusions | 17 | 0.375 | 43.733 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding |
46 |
HCFC2 | interactor | 4 | 1.000 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif |
47 |
HDAC1 | suppressor | 32 | 0.340 | 161.409 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
48 |
HDAC2 | suppressor | 26 | 0.490 | 45.937 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
49 |
HECW2 | interactor | 12 | 0.327 | 27.633 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57 RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 |
50 |
HIST1H2BG | oncoprotein | 7 | 0.381 | 6.037 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
51 |
HIST1H3A | interactor | 25 | 0.286 | 115.023 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
52 |
HIST1H4A | interactor | 18 | 0.359 | 44.536 | CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold |
53 |
HIST2H3C | interactor | 11 | 0.309 | 26.767 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
54 |
HIST3H3 | interactor | 28 | 0.270 | 151.595 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
55 |
HSPB1 | oncoprotein | 16 | 0.314 | 37.028 | HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
56 |
IMPDH1 | interactor | 5 | 0.800 | 0.619 | IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain |
57 |
IMPDH2 | protein found in more fusions | 12 | 0.364 | 22.934 | IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain |
58 |
ING4 | suppressor | 6 | 0.400 | 1.411 | PHD (PF00628, IPR019787, SM00249): PHD-finger SOGA (PF11365, IPR027881): Protein SOGA ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H (PF13771): PHD-like zinc-binding domain |
59 |
ITGA4 | interactor | 20 | 0.327 | 53.847 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
60 |
KAT6A | oncoprotein | 11 | 0.364 | 19.399 | BUD22 (PF09073, IPR015158): BUD22 MOZ_SAS (PF01853, IPR002717): MOZ/SAS family PHD (PF00628, IPR019787, SM00249): PHD-finger Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) zf-met (PF12874): Zinc-finger of C2H2 type |
61 |
KAT8 | protein found in more fusions | 12 | 0.400 | 17.756 | MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
62 |
KIF11 | protein found in more fusions | 8 | 0.429 | 4.637 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 Gag_p17 (PF00540, IPR000071): gag gene protein p17 (matrix protein) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein KxDL (PF10241, IPR019371): Uncharacterized conserved protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510) Microtub_bind (PF13931, IPR025901): Kinesin-associated microtubule-binding |
63 |
KIF7 | suppressor | 1 | 0 | 0 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) MMR_HSR1_C (PF08438, IPR013646): GTPase of unknown function C-terminal Nbs1_C (PF08599, IPR013908): DNA damage repair protein Nbs1 XhlA (PF10779, IPR019715): Haemolysin XhlA Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain YlqD (PF11068, IPR021297): YlqD protein DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) |
64 |
KRAS | oncoprotein | 7 | 0.400 | 6.122 | Ras (PF00071, IPR001806, SM00173): Ras family |
65 |
LEO1 | interactor | 10 | 0.689 | 5.792 | Leo1 (PF04004, IPR007149): Leo1-like protein PPP4R2 (PF09184, IPR015267): PPP4R2 EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region |
66 |
LGR4 | interactor | 5 | 0.500 | 1.900 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
67 |
MAP3K5 | oncoprotein | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071) |
68 |
MBD3 | interactor | 13 | 0.742 | 3.851 | DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain |
69 |
MCM2 | oncoprotein | 29 | 0.217 | 191.043 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
70 |
MLLT1 | oncoprotein | 15 | 0.448 | 33.721 | DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) Peptidase_S64 (PF08192, IPR012985): Peptidase family S64 YEATS (PF03366, IPR005033): YEATS family DDRGK (PF09756, IPR019153, SM01128): DDRGK domain |
71 |
MLLT3 | oncoprotein | 11 | 0.527 | 14.736 | Peptidase_S64 (PF08192, IPR012985): Peptidase family S64 YEATS (PF03366, IPR005033): YEATS family DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) Sox_N (PF12444, IPR022151): Sox developmental protein N terminal PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal NKAP (PF15692): NF-kappa-B-activating protein BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation |
72 |
MTAP | suppressor | 4 | 0.833 | 0.667 | PNP_UDP_1 (PF01048, IPR000845): Phosphorylase superfamily |
73 |
MTM1 | interactor | 1 | 0 | 0 | GRAM (PF02893, IPR004182, SM00568): GRAM domain Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain 3-PAP (PF12578, IPR022587): Myotubularin-associated protein |
74 |
MYB | oncoprotein | 8 | 0.464 | 4.833 | Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
75 |
NCL | protein found in more fusions | 21 | 0.337 | 66.348 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1 |
76 |
NTRK1 | oncoprotein | 43 | 0.174 | 472.797 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
77 |
OXT | interactor | 1 | 0 | 0 | Hormone_4 (PF00220, IPR022423): Neurohypophysial hormones, N-terminal Domain Hormone_5 (PF00184, IPR000981, SM00003): Neurohypophysial hormones, C-terminal Domain |
78 |
PAF1 | oncoprotein | 14 | 0.440 | 28.445 | Paf1 (PF03985, IPR007133): Paf1 MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 |
79 |
PAX6 | suppressor | 5 | 0.667 | 0.800 | PAX (PF00292, IPR001523, SM00351): 'Paired box' domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
80 |
PKN1 | interactor | 6 | 0.700 | 1.267 | C2 (PF00168, IPR000008, SM00239): C2 domain HR1 (PF02185, IPR011072, SM00742): Hr1 repeat Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
81 |
PNP | interactor | 13 | 0.273 | 38.430 | PNP_UDP_1 (PF01048, IPR000845): Phosphorylase superfamily |
82 |
POLR2A | protein found in more fusions | 19 | 0.359 | 56.891 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
83 |
PPIE | interactor | 4 | 0.833 | 0.333 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
84 |
PPME1 | protein found in more fusions | 8 | 0.429 | 10.167 | Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family |
85 |
PPP1R15A | interactor | 2 | 1.000 | 0 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region PP1c_bdg (PF10488, IPR019523): Phosphatase-1 catalytic subunit binding region SCHIP-1 (PF10148, IPR015649): Schwannomin-interacting protein 1 CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A |
86 |
PRKAG2 | interactor | 1 | 0 | 0 | CBS (PF00571, IPR000644, SM00116): CBS domain |
87 |
PSIP1 | oncoprotein | 2 | 1.000 | 0 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif BEX (PF04538, IPR021156): Brain expressed X-linked like family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) PGA2 (PF07543, IPR011431): Protein trafficking PGA2 PWWP (PF00855, IPR000313, SM00293): PWWP domain LEDGF (PF11467, IPR021567): Lens epithelium-derived growth factor (LEDGF) TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2 |
88 |
PSMD5 | interactor | 4 | 0.667 | 1.067 | Proteasom_PSMB (PF10508, IPR019538): Proteasome non-ATPase 26S subunit |
89 |
RAB1A | oncoprotein | 4 | 0.833 | 0.667 | Ras (PF00071, IPR001806, SM00173): Ras family |
90 |
RAN | oncoprotein | 12 | 0.288 | 30.849 | Ras (PF00071, IPR001806, SM00173): Ras family |
91 |
RBBP4 | oncoprotein | 23 | 0.458 | 49.137 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
92 |
RBBP5 | oncoprotein | 18 | 0.301 | 54.038 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
93 |
RBBP7 | suppressor | 20 | 0.532 | 37.385 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
94 |
RCN1 | interactor | 8 | 0.536 | 10.487 | EF-hand_1 (PF00036, IPR002048, SM00054): EF hand EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
95 |
RNF2 | interactor | 31 | 0.283 | 164.605 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
96 |
RPIA | interactor | 2 | 0 | 0 | Rib_5-P_isom_A (PF06026, IPR004788): Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind (PF04198, IPR007324): Putative sugar-binding domain |
97 |
RUNX1 | suppressor | 9 | 0.643 | 3.277 | Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037) |
98 |
SAP30 | interactor | 8 | 1.000 | 0 | Titin_Z (PF09042, IPR015129): Titin Z zf-SAP30 (PF13866, IPR025717): SAP30 zinc-finger SAP30_Sin3_bdg (PF13867, IPR025718): Sin3 binding region of histone deacetylase complex subunit SAP30 |
99 |
SBF1 | interactor | 4 | 0.667 | 0.451 | dDENN (PF03455, IPR005112, SM00801): dDENN domain DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain GRAM (PF02893, IPR004182, SM00568): GRAM domain Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain PH (PF00169, IPR001849, SM00233): PH domain uDENN (PF03456, IPR005113, SM00800): uDENN domain T2SSJ (PF11612, IPR010055): Type II secretion system (T2SS), protein J SBF2 (PF12335, IPR022096): Myotubularin protein |
100 |
SET | oncoprotein | 8 | 0.476 | 1.975 | NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) Nop14 (PF04147, IPR007276): Nop14-like family DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
101 |
SIN3A | oncoprotein | 25 | 0.407 | 78.669 | Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein |
102 |
SIRT7 | interactor | 24 | 0.275 | 98.021 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
103 |
SKP2 | suppressor | 6 | 0.400 | 7.667 | LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_2 (PF07723, IPR013101): Leucine Rich Repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) F-box-like (PF12937, IPR001810): F-box-like LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat |
104 |
SMARCA2 | suppressor | 24 | 0.395 | 69.376 | DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
105 |
SMARCC1 | suppressor | 16 | 0.495 | 16.979 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
106 |
SMARCC2 | interactor | 14 | 0.604 | 8.624 | GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain SWIRM (PF04433, IPR007526): SWIRM domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
107 |
SNW1 | protein found in more fusions | 27 | 0.298 | 127.460 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
108 |
SVIL | interactor | 4 | 0.500 | 2.333 | Gelsolin (PF00626, IPR007123): Gelsolin repeat VHP (PF02209, IPR003128, SM00153): Villin headpiece domain DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695) |
109 |
SYMPK | interactor | 8 | 0.571 | 5.427 | HEAT (PF02985, IPR000357): HEAT repeat DUF3453 (PF11935, IPR021850): Domain of unknown function (DUF3453) Symplekin_C (PF12295, IPR022075): Symplekin tight junction protein C terminal Cohesin_HEAT (PF12765, IPR026003): HEAT repeat associated with sister chromatid cohesion |
110 |
TAF1 | oncoprotein | 13 | 0.423 | 26.526 | Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit LcrG (PF07216, IPR009863): LcrG protein Opi1 (PF08618, IPR013927): Transcription factor Opi1 Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal TBP-binding (PF09247, IPR009067): TATA box-binding protein binding U3_snoRNA_assoc (PF08297, IPR013268): U3 snoRNA associated Bromodomain (PF00439, IPR001487, SM00297): Bromodomain DUF3591 (PF12157, IPR022591): Protein of unknown function (DUF3591) zf-CCHC_6 (PF15288): Zinc knuckle |
111 |
TAF6 | interactor | 19 | 0.573 | 23.155 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain Spo0A_C (PF08769, IPR014879): Sporulation initiation factor Spo0A C terminal TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF) |
112 |
TAF9 | interactor | 8 | 0.893 | 0.374 | TFIID-31kDa (PF02291, IPR003162): Transcription initiation factor IID, 31kD subunit DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
113 |
TBP | interactor | 17 | 0.475 | 30.909 | TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal |
114 |
TCEAL1 | interactor | 4 | 0.667 | 1.667 | BEX (PF04538, IPR021156): Brain expressed X-linked like family |
115 |
TCEB1 | oncoprotein | 7 | 0.476 | 8.500 | Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain |
116 |
TCEB2 | interactor | 7 | 0.476 | 6.273 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
117 |
TNRC6B | interactor | 5 | 0.700 | 1.500 | DUF1421 (PF07223, IPR010820): Protein of unknown function (DUF1421) Totivirus_coat (PF05518, IPR008871): Totivirus coat protein Ago_hook (PF10427, IPR019486): Argonaute hook DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TNRC6-PABC_bdg (PF16608, IPR032226): TNRC6-PABC binding domain RRM_occluded (PF16842, IPR031766): Occluded RNA-recognition motif |
118 |
TOP1 | oncoprotein | 14 | 0.495 | 16.887 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor Sox_N (PF12444, IPR022151): Sox developmental protein N terminal Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TonB_N (PF16031): TonB N-terminal region |
119 |
TP53 | suppressor | 39 | 0.220 | 325.320 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
120 |
TRIM21 | interactor | 6 | 0.400 | 3.383 | DUF313 (PF03754, IPR005508): Domain of unknown function (DUF313) SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
121 |
TSTA3 | interactor | 6 | 0.533 | 6.167 | Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family NICE-3 (PF07406, IPR010876): NICE-3 protein Polysacc_synt_2 (PF02719, IPR003869): Polysaccharide biosynthesis protein |
122 |
USP7 | oncoprotein | 15 | 0.385 | 39.643 | MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal |
123 |
VCAM1 | interactor | 13 | 0.385 | 18.054 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
124 |
WDR5 | interactor | 23 | 0.312 | 96.838 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
125 |
WDR61 | interactor | 7 | 0.810 | 1.619 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |