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for: AB795243 is the fusion of parental proteins SLC34A2, ROS1 (from a repository: Tue Feb 14 21:23:20 2017)
Statistics and Network structure information
List of active interactors
# |
Name |
Type |
Number of PPI (degree) |
Clustering Coefficient |
Betweenness Centrality |
Domains (Pfam, InterPro, SMART): description |
1 |
AB795243 | chimera | 5 | 0.300 | 11.000 | DUF805 (PF05656, IPR008523): Protein of unknown function (DUF805) Na_Pi_cotrans (PF02690, IPR003841): Na+/Pi-cotransporter Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase DUF2207 (PF09972, IPR018702): Predicted membrane protein (DUF2207) |
2 |
GRB2 | oncoprotein | 5 | 0.500 | 3.000 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
3 |
IKBKG | interactor | 2 | 0 | 0 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
4 |
PTPN11 | suppressor | 3 | 1.000 | 0 | SH2 (PF00017, IPR000980, SM00252): SH2 domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase |
5 |
PTPN6 | suppressor | 2 | 1.000 | 0 | SH2 (PF00017, IPR000980, SM00252): SH2 domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase PolyA_pol_arg_C (PF12626, IPR025866): Polymerase A arginine-rich C-terminus |
6 |
VAV3 | oncoprotein | 2 | 1.000 | 0 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain DUF2326 (PF10088, IPR018760): Uncharacterised protein conserved in bacteria (DUF2326) C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain PH_10 (PF15411): Pleckstrin homology domain |
B a c k t o T o p ⇑
List of missing interactors
# |
Name |
Type |
Domains (Pfam, InterPro, SMART): description |
Fusion(s) |
1 |
NUDCD1 | interactor | CS (PF04969, IPR007052): CS domain | |
2 |
ROS1 | parental protein | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) | |
3 |
SLC34A2 | parental protein | TMEM43 (PF07787, IPR012430): Transmembrane protein 43 Na_Pi_cotrans (PF02690, IPR003841): Na+/Pi-cotransporter SKG6 (PF08693, IPR014805): Transmembrane alpha-helix domain DUF2207 (PF09972, IPR018702): Predicted membrane protein (DUF2207) | |
B a c k t o T o p ⇑