1 |
AB795239 | chimera | 117 | 0.084 | 8688.478 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
2 |
ACTN1 | protein found in more fusions | 25 | 0.489 | 60.965 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Dak2 (PF02734, IPR004007, SM01120): DAK2 domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair Uds1 (PF15456, IPR029191): Up-regulated During Septation |
3 |
ACTN2 | protein found in more fusions | 8 | 0.857 | 0.908 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Nsp1_C (PF05064, IPR007758): Nsp1-like C-terminal region Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
4 |
ACTN4 | interactor | 27 | 0.447 | 79.033 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair Uds1 (PF15456, IPR029191): Up-regulated During Septation |
5 |
ADD1 | interactor | 6 | 0.867 | 0.382 | Aldolase_II (PF00596, IPR001303, SM01007): Class II Aldolase and Adducin N-terminal domain CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal |
6 |
AHCYL1 | suppressor | 9 | 0.393 | 9.819 | AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF515 (PF04415, IPR007509): Protein of unknown function (DUF515) Big_3_5 (PF16640, IPR032109): Bacterial Ig-like domain (group 3) |
7 |
ANLN | oncoprotein | 13 | 0.808 | 8.410 | Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus |
8 |
ATP1A1 | interactor | 10 | 0.400 | 11.892 | Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase Tetraspannin (PF00335, IPR018499): Tetraspanin family Cation_ATPase (PF13246): Cation transport ATPase (P-type) |
9 |
ATP5F1 | interactor | 10 | 0.422 | 11.522 | Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2105 (PF09878, IPR019212): Predicted membrane protein (DUF2105) |
10 |
BLOC1S6 | interactor | 5 | 0.500 | 3.000 | BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin |
11 |
BRCA1 | suppressor | 14 | 0.372 | 32.492 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
12 |
C1orf216 | interactor | 3 | 0.667 | 1.000 | DUF4653 (PF15546, IPR027812): Domain of unknown function (DUF4653) |
13 |
CAP1 | interactor | 11 | 0.733 | 3.351 | CAP_C (PF08603, IPR013912): Adenylate cyclase associated (CAP) C terminal CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator |
14 |
CAPZA2 | interactor | 22 | 0.537 | 41.897 | F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit |
15 |
CCDC102B | interactor | 6 | 0.700 | 2.000 | Filament (PF00038, IPR001664): Intermediate filament protein Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein Myosin_tail_1 (PF01576, IPR002928): Myosin tail PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
16 |
CCDC114 | interactor | 2 | 1.000 | 0 | FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) Histone_HNS (PF00816, IPR001801): H-NS histone family Hydantoinase_B (PF02538, IPR003692): Hydantoinase B/oxoprolinase DUF2353 (PF09789, IPR019179): Uncharacterized coiled-coil protein (DUF2353) PLAC9 (PF15205, IPR027941): Placenta-specific protein 9 |
17 |
CCDC146 | interactor | 3 | 0.667 | 1.000 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
18 |
CCHCR1 | interactor | 8 | 0.333 | 12.067 | HCR (PF07111, IPR009800): Alpha helical coiled-coil rod protein (HCR) |
19 |
CDC123 | interactor | 2 | 1.000 | 0 | D123 (PF07065, IPR009772): D123 |
20 |
CDK2 | suppressor | 29 | 0.349 | 117.038 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
21 |
CKB | interactor | 13 | 0.487 | 14.631 | ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain |
22 |
CKMT1A | interactor | 3 | 0.667 | 0.500 | ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain |
23 |
CKMT1B | interactor | 4 | 0.667 | 0.682 | ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain |
24 |
COX4I1 | interactor | 6 | 0.733 | 2.333 | COX4 (PF02936, IPR004203): Cytochrome c oxidase subunit IV |
25 |
COX5A | interactor | 6 | 0.533 | 3.347 | COX5A (PF02284, IPR003204): Cytochrome c oxidase subunit Va |
26 |
CUL3 | protein found in more fusions | 27 | 0.191 | 175.282 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
27 |
CUL7 | protein found in more fusions | 21 | 0.289 | 62.266 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
28 |
CYC1 | interactor | 9 | 0.389 | 11.733 | Cytochrom_C1 (PF02167, IPR002326): Cytochrome C1 family |
29 |
DAPK1 | suppressor | 8 | 0.524 | 3.587 | ABC_tran (PF00005, IPR003439): ABC transporter Death (PF00531, IPR000488, SM00005): Death domain Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) AAA_23 (PF13476): AAA domain Ank_5 (PF13857): Ankyrin repeats (many copies) COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
30 |
DVL2 | interactor | 8 | 0.571 | 4.706 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled (PF02377, IPR003351): Dishevelled specific domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DIX (PF00778, IPR001158, SM00021): DIX domain Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal |
31 |
EGFR | oncoprotein | 23 | 0.316 | 91.106 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
32 |
EIF4A2 | oncoprotein | 6 | 0.500 | 3.800 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
33 |
ELAVL1 | oncoprotein | 29 | 0.212 | 203.425 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
34 |
FAM9C | interactor | 1 | 0 | 0 | Cor1 (PF04803, IPR006888): Cor1/Xlr/Xmr conserved region DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) |
35 |
FASN | interactor | 16 | 0.457 | 24.776 | Acyl_transf_1 (PF00698, IPR014043): Acyl transferase domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ketoacyl-synt (PF00109, IPR014030): Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C (PF02801, IPR014031): Beta-ketoacyl synthase, C-terminal domain KR (PF08659, IPR013968, SM00130): KR domain L27 (PF02828, IPR014775, SM00569): L27 domain Methyltransf_12 (PF08242, IPR013217): Methyltransferase domain PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site Thioesterase (PF00975, IPR001031): Thioesterase domain YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase PS-DH (PF14765, IPR020807): Polyketide synthase dehydratase KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension |
36 |
FBXO5 | oncoprotein | 5 | 0.400 | 3.233 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain F-box (PF00646, IPR001810, SM00256): F-box domain |
37 |
FKBP4 | interactor | 11 | 0.655 | 5.875 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat |
38 |
FKBP5 | interactor | 10 | 0.556 | 11.741 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat NuDC (PF16273, IPR032572): Nuclear distribution C domain |
39 |
FN1 | oncoprotein | 20 | 0.342 | 51.487 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
40 |
GRB2 | oncoprotein | 18 | 0.404 | 47.057 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
41 |
HDAC8 | interactor | 5 | 0.500 | 1.829 | DNase-RNase (PF02577, IPR003729): Bifunctional nuclease Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
42 |
HDDC3 | interactor | 1 | 0 | 0 | HD_4 (PF13328, IPR003607): HD domain |
43 |
HOOK2 | interactor | 4 | 0.667 | 0.222 | HOOK (PF05622, IPR008636): HOOK protein |
44 |
HSF2 | interactor | 2 | 1.000 | 0 | HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding HMMR_C (PF15908, IPR031794): Hyaluronan mediated motility receptor C-terminal |
45 |
HSP90AA1 | oncoprotein | 32 | 0.312 | 155.960 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
46 |
HSP90AB1 | oncoprotein | 32 | 0.316 | 147.143 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
47 |
HSPB1 | oncoprotein | 21 | 0.337 | 82.619 | HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
48 |
IFIT3 | interactor | 3 | 1.000 | 0 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
49 |
IKBIP | interactor | 2 | 1.000 | 0 | Fez1 (PF06818): Fez1 Occludin_ELL (PF07303, IPR010844): Occludin homology domain GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) SesA (PF17107, IPR031352): N-terminal domain on NACHT_NTPase and P-loop NTPases |
50 |
IKBKG | interactor | 14 | 0.346 | 29.990 | CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
51 |
IQGAP1 | interactor | 29 | 0.419 | 98.434 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain |
52 |
KCNE1 | interactor | 1 | 0 | 0 | ISK_Channel (PF02060, IPR000369): Slow voltage-gated potassium channel |
53 |
KIFC3 | oncoprotein | 5 | 0.833 | 0.667 | Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein KxDL (PF10241, IPR019371): Uncharacterized conserved protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
54 |
KXD1 | interactor | 2 | 1.000 | 0 | KxDL (PF10241, IPR019371): Uncharacterized conserved protein |
55 |
KYNU | interactor | 3 | 0.667 | 1.000 | Aminotran_5 (PF00266, IPR000192): Aminotransferase class-V CaKB (PF03185, IPR003930): Calcium-activated potassium channel, beta subunit |
56 |
LCA5L | interactor | 1 | 0 | 0 | DUF1515 (PF07439, IPR010889): Protein of unknown function (DUF1515) Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain |
57 |
LRRK2 | oncoprotein | 11 | 0.511 | 8.996 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043) T2SSE (PF00437, IPR001482): Type II/IV secretion system protein Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) PQQ_2 (PF13360, IPR002372): PQQ-like domain LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
58 |
LURAP1 | interactor | 2 | 1.000 | 0 | LURAP (PF14854): Leucine rich adaptor protein DUF4530 (PF15039, IPR029202): Domain of unknown function (DUF4530) |
59 |
MAD1L1 | suppressor | 5 | 0.500 | 1.487 | MAD (PF05557, IPR008672): Mitotic checkpoint protein Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 |
60 |
MAGEA11 | interactor | 6 | 0.400 | 5.400 | MAGE (PF01454, IPR002190): MAGE family MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
61 |
MAGED2 | interactor | 11 | 0.564 | 9.098 | CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 MAGE (PF01454, IPR002190): MAGE family SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) |
62 |
MCC | suppressor | 2 | 1.000 | 0 | ERM (PF00769, IPR011259): Ezrin/radixin/moesin family IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein MCC-bdg_PDZ (PF10506, IPR019536): PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding EF-hand_7 (PF13499, IPR011992): EF-hand domain pair FAM76 (PF16046, IPR032017): FAM76 protein |
63 |
MCM2 | oncoprotein | 25 | 0.438 | 64.444 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
64 |
MCM3 | interactor | 13 | 0.526 | 11.143 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
65 |
MDC1 | suppressor | 9 | 0.528 | 10.164 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
66 |
MGEA5 | oncoprotein | 11 | 0.509 | 14.935 | NAGidase (PF07555, IPR011496): beta-N-acetylglucosaminidase |
67 |
MOV10 | interactor | 12 | 0.258 | 33.456 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
68 |
MTCH1 | interactor | 4 | 0.500 | 0.952 | YdjM (PF04307, IPR007404): LexA-binding, inner membrane-associated putative hydrolase Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
69 |
MYH7B | interactor | 7 | 0.714 | 2.650 | Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail YkuI_C (PF10388, IPR018842): EAL-domain associated signalling protein domain Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
70 |
MYH9 | suppressor | 25 | 0.550 | 39.858 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
71 |
MYO18A | interactor | 18 | 0.549 | 30.994 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_tail_1 (PF01576, IPR002928): Myosin tail PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
72 |
MYO19 | interactor | 15 | 0.781 | 5.501 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
73 |
MYO5C | interactor | 14 | 0.670 | 9.499 | DIL (PF01843, IPR018444, SM01132): DIL domain DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Pilus_CpaD (PF09476, IPR019027): Pilus biogenesis CpaD protein (pilus_cpaD) Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) YtxH (PF12732, IPR024623): YtxH-like protein Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
74 |
NDUFB10 | interactor | 5 | 0.700 | 1.083 | NDUFB10 (PF10249, IPR019377): NADH-ubiquinone oxidoreductase subunit 10 |
75 |
NEK2 | interactor | 6 | 0.400 | 5.400 | Pkinase (PF00069, IPR000719): Protein kinase domain |
76 |
NTRK1 | oncoprotein | 44 | 0.213 | 455.695 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
77 |
NXF1 | interactor | 14 | 0.321 | 33.012 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
78 |
OBSL1 | protein found in more fusions | 24 | 0.316 | 85.480 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
79 |
OIP5 | interactor | 3 | 0.667 | 0.500 | Yippee-Mis18 (PF03226, IPR004910): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly |
80 |
OSTF1 | interactor | 3 | 0.667 | 0.182 | SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
81 |
PAN2 | interactor | 14 | 0.505 | 18.397 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
82 |
PARK2 | suppressor | 14 | 0.385 | 24.865 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
83 |
PAXIP1 | interactor | 6 | 0.533 | 3.686 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase SURF6 (PF04935, IPR007019): Surfeit locus protein 6 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
84 |
PBX3 | interactor | 1 | 0 | 0 | Homeobox_KN (PF05920, IPR008422): Homeobox KN domain PBC (PF03792, IPR005542): PBC domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
85 |
PDLIM7 | interactor | 15 | 0.581 | 18.532 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
86 |
PPP1CB | interactor | 20 | 0.605 | 25.031 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
87 |
PPP1CC | oncoprotein | 15 | 0.400 | 35.254 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
88 |
PRDX1 | oncoprotein | 11 | 0.422 | 6.182 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
89 |
PSMA2 | interactor | 7 | 0.733 | 0.863 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
90 |
PSMA6 | interactor | 12 | 0.379 | 20.212 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
91 |
PTPN11 | suppressor | 7 | 0.733 | 1.044 | SH2 (PF00017, IPR000980, SM00252): SH2 domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase |
92 |
PTPN6 | suppressor | 4 | 0.667 | 1.667 | SH2 (PF00017, IPR000980, SM00252): SH2 domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase PolyA_pol_arg_C (PF12626, IPR025866): Polymerase A arginine-rich C-terminus |
93 |
RAD21 | oncoprotein | 10 | 0.533 | 9.375 | Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
94 |
RNF2 | interactor | 12 | 0.273 | 23.345 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
95 |
SEC23IP | interactor | 3 | 0.667 | 1.000 | DDHD (PF02862, IPR004177, SM01127): DDHD domain SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) WWE (PF02825, IPR004170, SM00678): WWE domain |
96 |
SEPT9 | oncoprotein | 6 | 0.333 | 3.443 | Septin (PF00735, IPR000038): Septin DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) |
97 |
SF3A2 | interactor | 7 | 0.667 | 2.652 | Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like Totivirus_coat (PF05518, IPR008871): Totivirus coat protein zf-met (PF12874): Zinc-finger of C2H2 type ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) |
98 |
SHMT2 | interactor | 9 | 0.333 | 11.138 | SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase |
99 |
SP1 | protein found in more fusions | 12 | 0.618 | 8.642 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
100 |
STMN1 | interactor | 7 | 0.429 | 5.004 | Stathmin (PF00836, IPR000956): Stathmin family |
101 |
SYCE1 | interactor | 5 | 0.500 | 3.952 | CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit SYCE1 (PF15233, IPR026676): Synaptonemal complex central element protein 1 |
102 |
TBCD | interactor | 4 | 0.833 | 0.286 | HEAT (PF02985, IPR000357): HEAT repeat HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal HEAT_EZ (PF13513): HEAT-like repeat |
103 |
TFPT | oncoprotein | 3 | 1.000 | 0 | GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor |
104 |
THAP1 | interactor | 4 | 1.000 | 0 | THAP (PF05485, IPR006612, SM00980): THAP domain Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2 Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57 |
105 |
THOC1 | protein found in more fusions | 5 | 0.500 | 0.915 | Death (PF00531, IPR000488, SM00005): Death domain efThoc1 (PF11957, IPR021861): THO complex subunit 1 transcription elongation factor |
106 |
TLK1 | protein found in more fusions | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Vir_act_alpha_C (PF10400, IPR018309): Virulence activator alpha C-term |
107 |
TNNT1 | protein found in more fusions | 4 | 0.667 | 0.154 | Troponin (PF00992, IPR001978): Troponin DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050) |
108 |
TP53 | suppressor | 28 | 0.288 | 145.193 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
109 |
TP73 | suppressor | 5 | 1.000 | 0 | P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
110 |
TPM1 | protein found in more fusions | 41 | 0.221 | 418.833 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
111 |
TPM2 | protein found in more fusions | 28 | 0.362 | 135.421 | DASH_Spc19 (PF08287, IPR013251): Spc19 Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
112 |
TPM4 | oncoprotein | 38 | 0.270 | 300.287 | Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like |
113 |
TRAP1 | oncoprotein | 12 | 0.424 | 15.323 | HSP90 (PF00183, IPR001404): Hsp90 protein HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase |
114 |
TRIM27 | oncoprotein | 9 | 0.357 | 16.056 | IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
115 |
TRIP6 | interactor | 8 | 0.357 | 13.633 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region LIM (PF00412, IPR001781, SM00132): LIM domain |
116 |
UQCRC2 | oncoprotein | 8 | 0.571 | 6.003 | Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain |
117 |
VAV3 | oncoprotein | 3 | 1.000 | 0 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain DUF2326 (PF10088, IPR018760): Uncharacterised protein conserved in bacteria (DUF2326) C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain PH_10 (PF15411): Pleckstrin homology domain |
118 |
VPS52 | interactor | 4 | 0.667 | 1.000 | Vps52 (PF04129, IPR007258): Vps52 / Sac2 family COG5 (PF10392, IPR019465): Golgi transport complex subunit 5 Sec3_C (PF09763, IPR019160): Exocyst complex component Sec3 |