Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: AA743965 is the fusion of parental proteins AP2M1 (from a repository: Tue Dec 6 12:02:33 2016)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)201
The number (and %) of the onco-proteins48 (23.88 %)
The number (and %) of the tumor suppressors20 (9.95 %)
Total number of binary PPIs (saturation %)1405 (6.99 %)
The number (and %) of affected PPIs200 (14.23 %)
The number of possible different fusions28
PPI diameter2
PPI radius1
The average degree of PPI13.502
Assortativity coefficient-0.3294
The network average Clustering coefficient0.499
The number (and %) of a zero Clustering coefficients32 (15.92 %)
The number (and %) of a zero Betweenness Centrality55 (27.36 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: AP2M1 All fusions
: AA743965;
Proteins found in more fusions STAU1 (see 2 fusions); EPS15 (see 1 fusions); EEF1A1 (see 1 fusions); DCAF1 (see 1 fusions); CUL3 (see 1 fusions); GRB2 (see 1 fusions); REPS1 (see 1 fusions); IKZF1 (see 1 fusions); CDH1 (see 3 fusions); ACTB (see 3 fusions); PRKDC (see 3 fusions); APC (see 1 fusions); PJA2 (see 1 fusions); PEX14 (see 1 fusions); UBC (see 1 fusions); ITSN2 (see 1 fusions); BCR/ABL1 (see 183 fusions); RNF11 (see 1 fusions); CRY2 (see 3 fusions); SFPQ (see 6 fusions); GFAP (see 3 fusions); MARK2 (see 2 fusions); FCHO2/CLTC (see 1 fusions); CLINT1 (see 2 fusions); EGFR (see 2 fusions); SHC1 (see 1 fusions); GAPDH (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AA743965chimera2010.05828132.648Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
2 AAK1interactor90.8610.679eIF-3_zeta (PF05091, IPR007783): Eukaryotic translation initiation factor 3 subunit 7 (eIF-3)
Pkinase (PF00069, IPR000719): Protein kinase domain
3 ABL1oncoprotein180.49326.927Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
4 ACACAinteractor40.8330.065ACC_central (PF08326, IPR013537): Acetyl-CoA carboxylase, central region
Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain
Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
DUF445 (PF04286, IPR007383): Protein of unknown function (DUF445)
5 ACTBoncoprotein250.44651.634Actin (PF00022, IPR004000, SM00268): Actin
6 ADRA1Binteractor1007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
7tm_4 (PF13853): Olfactory receptor
Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator
7 AKAP11interactor30.6670.667E_raikovi_mat (PF06360, IPR009064): Euplotes raikovi mating pheromone
RNA_lig_T4_1 (PF09511, IPR019039): RNA ligase
8 AMER1suppressor41.0000CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
WTX (PF09422, IPR019003): WTX protein
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
9 ANKRD28interactor50.5003.500Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
10 ANKRD52interactor31.0000Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
11 ANLNoncoprotein260.66226.590Anillin (PF08174, IPR012966): Cell division protein anillin
PH (PF00169, IPR001849, SM00233): PH domain
Anillin_N (PF16018, IPR031970): Anillin N-terminus
12 AP1B1interactor180.49032.818Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain
13 AP1G1interactor160.50830.666Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
14 AP1G2interactor60.6673.952Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
15 AP1S1interactor80.7862.146Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
16 AP1S2interactor80.7862.192Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
17 AP1S3interactor100Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
18 AP2A1interactor460.370268.704Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
HEAT_2 (PF13646): HEAT repeats
19 AP2A2interactor220.59722.032Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
HEAT_2 (PF13646): HEAT repeats
20 AP2B1interactor410.367217.883Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain
21 AP2S1interactor140.6269.240Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
22 APCsuppressor180.22868.175APC_15aa (PF05972, IPR009240): APC 15 residue motif
APC_basic (PF05956, IPR009234): APC basic domain
APC_r (PF05923): APC repeat
Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EB1_binding (PF05937, IPR009232): EB-1 Binding Domain
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
SAMP (PF05924, IPR009224): SAMP Motif
Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4
Arm_APC_u3 (PF16629): Armadillo-associated region on APC
APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs
APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions
APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP
APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
23 AQP4interactor100MIP (PF00230, IPR000425): Major intrinsic protein
24 ARRB2interactor360.252201.743Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
25 ATG16L1interactor60.5001.295ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2332 (PF10094, IPR011200): Uncharacterized protein conserved in bacteria (DUF2332)
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
26 ATXN1Linteractor50.5002.667AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
27 ATXN2Linteractor50.7000.554LsmAD (PF06741, IPR009604): LsmAD domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
28 BCRsuppressor80.8570.562Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
IQ_SEC7_PH (PF16453, IPR001849): PH domain
29 BMP2Kinteractor220.65416.625Pkinase (PF00069, IPR000719): Protein kinase domain
TCP (PF03634, IPR005333): TCP family transcription factor
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
EOS1 (PF12326, IPR021100): N-glycosylation protein
BMP2K_C (PF15282, IPR028182): BMP-2-inducible protein kinase C-terminus
PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator
FAM60A (PF15396, IPR026065): Protein Family FAM60A
30 C1orf226interactor100DUF4628 (PF15429, IPR027851): Domain of unknown function (DUF4628)
31 CACNA1Ainteractor21.0000Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain
GRP (PF07172, IPR010800): Glycine rich protein family
Ion_trans (PF00520, IPR005821): Ion transport protein
Roughex (PF06020, IPR009259): Drosophila roughex protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
32 CALCOCO1interactor21.0000CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
33 CAPZA2interactor280.63846.134F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
34 CD22interactor41.0000C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
35 CDH1suppressor120.40017.079Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
36 CDH3interactor51.0000Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
LSR (PF05624, IPR008664): Lipolysis stimulated receptor (LSR)
DUF2207 (PF09972, IPR018702): Predicted membrane protein (DUF2207)
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
37 CDK11Boncoprotein50.6670.952DDHD (PF02862, IPR004177, SM01127): DDHD domain
DivIC (PF04977, IPR007060): Septum formation initiator
Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748)
38 CHD8oncoprotein21.0000BUD22 (PF09073, IPR015158): BUD22
CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
BRK (PF07533, IPR006576, SM00592): BRK domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
FAM176 (PF14851): FAM176 family
Myb_DNA-bind_7 (PF15963): Myb DNA-binding like
39 CLEC4Minteractor200Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
DUF2730 (PF10805, IPR020269): Protein of unknown function (DUF2730)
40 CLINT1protein found in more fusions260.61042.090ENTH (PF01417, IPR001026, SM00273): ENTH domain
41 CLTBinteractor300.63734.836Clathrin_lg_ch (PF01086, IPR000996): Clathrin light chain
42 CLTConcoprotein480.347329.941Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
Clathrin_H_link (PF13838): Clathrin-H-link
43 COLEC12interactor100Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
Filament (PF00038, IPR001664): Intermediate filament protein
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
44 CORO1Concoprotein190.52628.853DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
WD40_4 (PF16300): Type of WD40 repeat
45 CORO7interactor40.8330.667DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_4 (PF16300): Type of WD40 repeat
46 CRKoncoprotein440.224343.206SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
47 CRY1interactor190.22944.805DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
48 CRY2protein found in more fusions160.30538.439DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
49 CSNK2Binteractor160.31444.565CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
50 CTLA4interactor200V-set (PF07686, IPR013106): Immunoglobulin V-set domain
51 CTNNB1oncoprotein210.281100.526Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
52 CTNND1suppressor80.6434.362Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
53 CUL3protein found in more fusions580.136863.604Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
54 DAB2suppressor290.51277.604PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz
55 DBN1oncoprotein320.61739.344Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
56 DCAF1protein found in more fusions50.6670.444DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
LisH (PF08513, IPR013720, SM00667): LisH
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
57 DDX3Xsuppressor110.4364.231DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
58 DDX47interactor41.0000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
59 DDX6oncoprotein100.31123.037DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
60 DGKIinteractor100Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
DAGK_acc (PF00609, IPR000756, SM00045): Diacylglycerol kinase accessory domain
DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
61 DIEXFinteractor21.0000UTP25 (PF06862, IPR010678): Utp25, U3 small nucleolar RNA-associated SSU processome protein 25
eIF-3c_N (PF05470, IPR008905): Eukaryotic translation initiation factor 3 subunit 8 N-terminus
SDA1 (PF05285, IPR007949): SDA1
62 DPPA2interactor40.6670.667SAP (PF02037, IPR003034, SM00513): SAP domain
DCR (PF14047, IPR025891): Dppa2/4 conserved region
Dppa2_A (PF14049, IPR025892): Dppa2/4 conserved region in higher vertebrates
63 DVL2interactor120.32726.419DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Dishevelled (PF02377, IPR003351): Dishevelled specific domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DIX (PF00778, IPR001158, SM00021): DIX domain
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
64 EEF1A1suppressor230.42947.622GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
65 EGFRoncoprotein470.246407.042Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
66 EHD2interactor31.0000Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EHD_N (PF16880, IPR031692): N-terminal EH-domain containing protein
67 EPHA2suppressor110.7783.015fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
68 EPN1interactor200.45348.975ENTH (PF01417, IPR001026, SM00273): ENTH domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
69 EPS15oncoprotein670.234928.737Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
70 EPS15L1oncoprotein80.3578.360CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
71 ESR1suppressor330.272159.624Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
72 FAM199Xinteractor100FAM199X (PF15814, IPR029672): Protein family FAM199X
73 FAM208Ainteractor100DUF3715 (PF12509, IPR022188): Protein of unknown function (DUF3715)
74 FASNinteractor110.2677.087Acyl_transf_1 (PF00698, IPR014043): Acyl transferase domain
ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
ketoacyl-synt (PF00109, IPR014030): Beta-ketoacyl synthase, N-terminal domain
Ketoacyl-synt_C (PF02801, IPR014031): Beta-ketoacyl synthase, C-terminal domain
KR (PF08659, IPR013968, SM00130): KR domain
L27 (PF02828, IPR014775, SM00569): L27 domain
Methyltransf_12 (PF08242, IPR013217): Methyltransferase domain
PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site
Thioesterase (PF00975, IPR001031): Thioesterase domain
YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
PS-DH (PF14765, IPR020807): Polyketide synthase dehydratase
KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
75 FCHO2protein found in more fusions140.8133.062DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
PIN_2 (PF10130, IPR002716): PIN domain
muHD (PF10291, IPR018808): Muniscin C-terminal mu homology domain
76 FLNAsuppressor350.49197.609CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
77 FN1oncoprotein540.213491.054fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
78 FURINinteractor100DUF357 (PF04010, IPR023140): Protein of unknown function (DUF357)
P_proprotein (PF01483, IPR002884): Proprotein convertase P-domain
Peptidase_S8 (PF00082, IPR000209): Subtilase family
VSP (PF03302, IPR005127): Giardia variant-specific surface protein
Furin-like_2 (PF15913, IPR006212): Furin-like repeat, cysteine-rich
S8_pro-domain (PF16470, IPR032815): Peptidase S8 pro-domain
79 FXR2interactor50.5002.333Agenet (PF05641, IPR008395, SM00743): Agenet domain
REV (PF00424, IPR000625): REV protein (anti-repression trans-activator protein)
KH_1 (PF00013, IPR004088, SM00322): KH domain
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
80 GAKoncoprotein180.7457.129DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
81 GAPDHoncoprotein180.6109.266Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
82 GFAPprotein found in more fusions50.6670.472Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
83 GLP1Rinteractor1007tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family)
HRM (PF02793, IPR001879, SM00008): Hormone receptor domain
84 GRB2oncoprotein540.257488.796SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
85 GTSE1interactor340.433150.049GTSE1_N (PF15259, IPR032768): G-2 and S-phase expressed 1
86 GULP1interactor100PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
87 HAT1interactor40.8330.200Hat1_N (PF10394, IPR019467): Histone acetyl transferase HAT1 N-terminus
Acetyltransf_7 (PF13508, IPR000182): Acetyltransferase (GNAT) domain
Acetyltransf_10 (PF13673, IPR000182): Acetyltransferase (GNAT) domain
88 HNRNPA2B1oncoprotein150.47614.636RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
89 HSPA1Ainteractor190.40944.102HSP70 (PF00012, IPR013126): Hsp70 protein
90 HSPA1Binteractor150.38110.913HSP70 (PF00012, IPR013126): Hsp70 protein
91 HSPA1Linteractor140.50510.069HSP70 (PF00012, IPR013126): Hsp70 protein
92 HSPA6interactor70.7620.844HSP70 (PF00012, IPR013126): Hsp70 protein
93 HSPA8oncoprotein300.384109.590HSP70 (PF00012, IPR013126): Hsp70 protein
94 HSPA9oncoprotein170.49328.143HSP70 (PF00012, IPR013126): Hsp70 protein
95 IFNAR1oncoprotein100Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III
Tissue_fac (PF01108, IPR003961): Tissue factor
96 IKZF1suppressor40.6671.000Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
97 INTUinteractor100PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
98 IQGAP1interactor340.444146.428CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
IDEAL (PF08858, IPR014957, SM00914): IDEAL domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
WW (PF00397, IPR001202, SM00456): WW domain
99 ITGA4interactor410.269201.920FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
100 ITSN1interactor150.37428.487C2 (PF00168, IPR000008, SM00239): C2 domain
VIT1 (PF01988, IPR008217): VIT family
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon
GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748)
INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
101 ITSN2protein found in more fusions70.6002.638C2 (PF00168, IPR000008, SM00239): C2 domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26
VIR_N (PF15912, IPR031801): Virilizer, N-terminal
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
102 KBTBD6interactor31.0000BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_4 (PF13418): Galactose oxidase, central domain
Kelch_6 (PF13964): Kelch motif
103 KBTBD7interactor40.6671.200BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_2 (PF07646, IPR011498): Kelch motif
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_4 (PF13418): Galactose oxidase, central domain
Kelch_6 (PF13964): Kelch motif
104 KCNQ1interactor100Ion_trans (PF00520, IPR005821): Ion transport protein
KCNQ_channel (PF03520, IPR013821): KCNQ voltage-gated potassium channel
Sensor (PF13796, IPR025828): Putative sensor
105 KIAA0232interactor100DUF4603 (PF15376, IPR027871): Domain of unknown function (DUF4603)
106 KIF13Ainteractor31.0000FHA (PF00498, IPR000253, SM00240): FHA domain
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
KIF1B (PF12423, IPR022140): Kinesin protein 1B
DUF3694 (PF12473, IPR022164): Kinesin protein
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
FAM184 (PF15665): Family with sequence similarity 184, A and B
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
107 KRT1interactor170.55120.917Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
Keratin_2_head (PF16208, IPR032444): Keratin type II head
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
108 KRT10interactor160.57513.688Filament (PF00038, IPR001664): Intermediate filament protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
109 KRT14interactor90.6673.229Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
Keratin_2_head (PF16208, IPR032444): Keratin type II head
110 KRT16interactor100.7561.074Filament (PF00038, IPR001664): Intermediate filament protein
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
111 KRT17interactor70.7142.077DUF1798 (PF08807, IPR014913): Bacterial domain of unknown function (DUF1798)
Filament (PF00038, IPR001664): Intermediate filament protein
112 KRT2interactor130.6416.958Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
113 KRT3interactor60.9330.069Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
114 KRT5interactor140.64812.024Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
115 KRT6Ainteractor70.8100.759Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
116 KRT6Binteractor30.6670.071Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
117 KRT73oncoprotein41.0000Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
118 KRT77interactor61.0000Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
119 KRT79interactor31.0000Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
120 KRT9interactor110.6003.580Filament (PF00038, IPR001664): Intermediate filament protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
121 LIMA1suppressor300.63034.642LIM (PF00412, IPR001781, SM00132): LIM domain
ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
122 LY9interactor100ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
123 MAGEC2interactor100MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
APOC4 (PF15119, IPR028120): Apolipoprotein C4
124 MAGED4Binteractor100MAGE (PF01454, IPR002190): MAGE family
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
125 MAP4oncoprotein50.7001.082SdiA-regulated (PF06977, IPR009722): SdiA-regulated
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
126 MARK2protein found in more fusions50.5002.333DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702)
KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
127 MASP1interactor21.0000CUB (PF00431, IPR000859, SM00042): CUB domain
Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
Trypsin (PF00089, IPR001254, SM00020): Trypsin
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
128 MEA1interactor21.0000MEA1 (PF06910, IPR009685): Male enhanced antigen 1 (MEA1)
129 MED4interactor70.3816.085Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
130 MEGF10interactor100DSL (PF01414, IPR001774, SM00051): Delta serrate ligand
EGF_2 (PF07974, IPR013111): EGF-like domain
Syndecan (PF01034, IPR027789): Syndecan domain
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
131 MRPL58interactor50.5003.333RF-1 (PF00472, IPR000352): RF-1 domain
132 MYH9suppressor370.505123.274IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
133 MYO18Ainteractor240.67833.234Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
134 MYO19interactor260.69527.295IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
135 NAGPAinteractor31.0000EGF_2 (PF07974, IPR013111): EGF-like domain
NAGPA (PF09992, IPR018711): Phosphodiester glycosidase
136 NCOR2oncoprotein40.5003.000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK)
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family
PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Spt20 (PF12090, IPR021950): Spt20 family
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518)
GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
137 NDRG1suppressor80.3938.888Ndr (PF03096, IPR004142): Ndr family
138 NECAP1interactor60.8670.450DUF1681 (PF07933, IPR012466): Protein of unknown function (DUF1681)
139 NECAP2interactor130.50019.431DUF1681 (PF07933, IPR012466): Protein of unknown function (DUF1681)
140 NKAPinteractor31.0000SynMuv_product (PF06047, IPR009269): Ras-induced vulval development antagonist
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
NKAP (PF15692): NF-kappa-B-activating protein
141 NOS1APinteractor30.6671.000Phage_GPO (PF05929, IPR009228): Phage capsid scaffolding protein (GPO) serine peptidase
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
142 NUMBsuppressor130.6926.588NumbF (PF06311, IPR010449): NUMB domain
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
143 OTUD6Binteractor21.0000Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
HemY_N (PF07219, IPR010817): HemY protein N-terminus
OTU (PF02338, IPR003323): OTU-like cysteine protease
DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335)
144 PDLIM7interactor150.66713.489LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
145 PER1oncoprotein70.6195.167PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
SPX (PF03105, IPR004331): SPX domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Period_C (PF12114, IPR022728): Period protein 2/3C-terminal region
146 PEX14protein found in more fusions90.5007.355HemX (PF04375, IPR007470): HemX, putative uroporphyrinogen-III C-methyltransferase
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
147 PEX5interactor40.5001.178TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
SHNi-TPR (PF10516, IPR019544): SHNi-TPR
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_15 (PF13429): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
148 PICALMoncoprotein280.60138.609ANTH (PF07651, IPR011417): ANTH domain
149 PJA1interactor50.5000.633zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
150 PJA2protein found in more fusions40.6670.100zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
151 PLRG1interactor30.6670.100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
152 PPHLN1interactor100Lge1 (PF11488): Transcriptional regulatory protein LGE1
HERV-K_REC (PF15695): Rec (regulator of expression encoded by corf) of HERV-K-113
153 PPP6R2interactor60.4675.543SAMP (PF05924, IPR009224): SAMP Motif
SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
154 PRKACBinteractor50.6003.333Pkinase (PF00069, IPR000719): Protein kinase domain
155 PRKAR1Binteractor60.6001.520RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
156 PRKDCprotein found in more fusions170.32530.333FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
157 RAB7Asuppressor60.6002.173Ras (PF00071, IPR001806, SM00173): Ras family
158 RALBP1interactor70.7142.165DDHD (PF02862, IPR004177, SM01127): DDHD domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SlyX (PF04102, IPR007236): SlyX
Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505)
Nod1 (PF17114, IPR032634): Gef2-related medial cortical node protein Nod1
159 RALGAPA1interactor100Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
160 REPS1protein found in more fusions90.4297.458Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
MCLC (PF05934, IPR009231): Mid-1-related chloride channel (MCLC)
DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
161 REXO1interactor100TIL (PF01826, IPR002919): Trypsin Inhibitor like cysteine rich domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
EloA-BP1 (PF15870, IPR031736): ElonginA binding-protein 1
162 RNF11protein found in more fusions100.5284.988zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger
163 RPL38interactor60.5330.904Ribosomal_L38e (PF01781, IPR002675): Ribosomal L38e protein family
164 RPS27Ainteractor100.42210.407DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
165 RRP12interactor31.0000NUC173 (PF08161, IPR012978): NUC173 domain
PGA2 (PF07543, IPR011431): Protein trafficking PGA2
PPP4R2 (PF09184, IPR015267): PPP4R2
Ribosomal_L37 (PF08561, IPR013870): Mitochondrial ribosomal protein L37
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
166 RSPH14interactor100Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
167 RUNDC3Ainteractor21.0000Phage_GP20 (PF06810, IPR009636): Phage minor structural protein GP20
RUN (PF02759, IPR004012, SM00593): RUN domain
168 RUVBL2oncoprotein180.37535.459TIP49 (PF06068, IPR010339): TIP49 C-terminus
169 SERPINB12interactor100Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
170 SFPQoncoprotein120.5094.839GRP (PF07172, IPR010800): Glycine rich protein family
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
171 SHC1oncoprotein500.197429.413PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
172 SLC25A4interactor40.6671.286Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
173 SLC25A41interactor130.39717.598Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
174 SLC25A5interactor120.42418.811Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
175 SLC25A6interactor70.5334.500Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
176 SNX29oncoprotein100bZIP_1 (PF00170, IPR004827): bZIP transcription factor
PX (PF00787, IPR001683, SM00312): PX domain
RUN (PF02759, IPR004012, SM00593): RUN domain
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
UPF0054 (PF02130, IPR002036): Uncharacterized protein family UPF0054
NYD-SP28 (PF14772): Sperm tail
177 SPECC1Linteractor130.57710.995CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
DUF4763 (PF15960, IPR031883): Domain of unknown function (DUF4763)
178 SPTBN1suppressor200.50531.056CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Spectrin (PF00435, IPR002017): Spectrin repeat
PH_9 (PF15410): Pleckstrin homology domain
179 STAU1protein found in more fusions260.30757.643dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
180 STK11suppressor50.5003.917Pkinase (PF00069, IPR000719): Protein kinase domain
181 STON2interactor230.55734.647Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Stonin2_N (PF12016, IPR022699): Stonin 2
182 STX8interactor100CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
SNARE (PF05739, IPR000727, SM00397): SNARE domain
HD_assoc (PF13286, IPR026875): Phosphohydrolase-associated domain
183 SV2Ainteractor100MFS_1 (PF07690, IPR011701): Major Facilitator Superfamily
Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter
Pentapeptide_4 (PF13599, IPR001646): Pentapeptide repeats (9 copies)
184 SYNJ1interactor60.7330.940DUF1866 (PF08952, IPR015047, SM01165): Domain of unknown function (DUF1866)
Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
Syja_N (PF02383, IPR002013): SacI homology domain
YppG (PF14179, IPR025555): YppG-like protein
185 SYNPOinteractor250.68322.352Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin)
186 TBC1D5interactor21.0000RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
187 TGOLN2interactor100MSA_2 (PF00985, IPR001136): Merozoite Surface Antigen 2 (MSA-2) family
UCR_TM (PF02921, IPR004192): Ubiquinol cytochrome reductase transmembrane region
SbcCD_C (PF13558): Putative exonuclease SbcCD, C subunit
TUTF7_u4 (PF16631): Unstructured region 4 on terminal uridylyltransferase 7
188 TNKS2interactor200Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
189 TSSC4suppressor100TSSC4 (PF15264, IPR029338): Tumour suppressing sub-chromosomal transferable candidate 4
190 TUBA1Aoncoprotein190.49735.330Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
191 TUBA1Binteractor120.56111.078Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
192 TUBA1Cinteractor170.53717.107Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
193 TUBA4Binteractor90.8890.461Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
194 TUBBinteractor240.49642.005Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
195 TUBB2Ainteractor120.6365.571Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
196 TUBB3interactor120.5616.697Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
197 TUBB4Binteractor190.50331.817Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
198 UBCprotein found in more fusions270.292121.573ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
199 VCAM1interactor420.231228.467C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
200 XPO1interactor620.1441143.730CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
201 ZBTB8Ainteractor50.5002.000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger

B a c k    t o    T o p ⇑


List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 AP2M1parental proteinAdap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain

B a c k    t o    T o p ⇑