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Visible interactions: all affected independent (normal) missing nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)120
The number (and %) of the onco-proteins29 (24.17 %)
The number (and %) of the tumor suppressors13 (10.83 %)
Total number of binary PPIs (saturation %)1243 (17.41 %)
The number (and %) of affected PPIs119 (9.57 %)
The number of possible different fusions20
PPI diameter2
PPI radius1
The average degree of PPI19.833
Assortativity coefficient-0.2175
The network average Clustering coefficient0.538
The number (and %) of a zero Clustering coefficients7 (5.83 %)
The number (and %) of a zero Betweenness Centrality16 (13.33 %)

ACTIVE INTERACTORS
MISSING INTERACTORS


List of the fusions

PPI for parental proteins: RBMX All fusions
: AA461092;
Proteins found in more fusions STAU1 (see 2 fusions); EEF1A1 (see 1 fusions); U2AF2 (see 2 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); IVNS1ABP (see 2 fusions); HDAC5 (see 1 fusions); DDX5 (see 1 fusions); SNW1 (see 1 fusions); ITSN2 (see 1 fusions); SREK1 (see 4 fusions); HNRNPUL1 (see 1 fusions); JAK2 (see 3 fusions); SRPK2 (see 1 fusions); HNRNPD (see 1 fusions); KHDRBS1 (see 1 fusions); MCM2 (see 1 fusions); QKI (see 3 fusions); HNRNPC (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 AA461092chimera1190.1536559.368RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family
2 AHSA1interactor90.7781.186Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal
AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
3 C10orf2interactor100T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
AAA_25 (PF13481): AAA domain
4 CAND1interactor540.368303.131Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
5 CCDC33interactor50.6001.752C2 (PF00168, IPR000008, SM00239): C2 domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
SlyX (PF04102, IPR007236): SlyX
6 CCDC8interactor240.55331.701Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
7 CDC5Linteractor390.54974.715OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
8 CLK1interactor150.53810.231PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
Pkinase (PF00069, IPR000719): Protein kinase domain
9 CLK3interactor90.5368.286Pkinase (PF00069, IPR000719): Protein kinase domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
10 CNBPoncoprotein90.5833.252zf-CCHC (PF00098, IPR001878): Zinc knuckle
zf-ribbon_3 (PF13248): zinc-ribbon domain
11 CTNNB1oncoprotein150.60013.011Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
12 CUL3protein found in more fusions560.337347.758Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
13 CUL7protein found in more fusions410.47889.016ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
14 DDX5oncoprotein450.495112.921DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
15 DHX15interactor400.50484.052DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AAA_29 (PF13555): P-loop containing region of AAA domain
16 DHX36interactor70.6191.425DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
17 EEDsuppressor370.444105.250WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
18 EEF1A1suppressor300.45645.172GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
19 EIF4A3interactor450.519108.217DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
20 ESR1suppressor320.47368.604Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
21 FAM103A1interactor40.6671.333RAM (PF15320, IPR028271): mRNA cap methylation, RNMT-activating mini protein
22 FAM120Ainteractor120.6363.703TPR_15 (PF13429): Tetratricopeptide repeat
23 FASTKD2interactor31.0000FAST_1 (PF06743, IPR010622): FAST kinase-like protein, subdomain 1
FAST_2 (PF08368, IPR013579): FAST kinase-like protein, subdomain 2
RAP (PF08373, IPR013584, SM00952): RAP domain
24 FBXO6interactor200.53222.307FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
25 FBXW11interactor250.33070.220WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
26 FBXW7suppressor70.5331.562Mem_trans (PF03547, IPR004776): Membrane transport protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
F-box-like (PF12937, IPR001810): F-box-like
27 FN1oncoprotein320.49071.669fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
28 FOXL2suppressor21.0000K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
29 FOXM1oncoprotein100EspF (PF04806, IPR006891): EspF protein repeat
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
30 FUSsuppressor320.49259.760Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
31 FXR2interactor100.41712.199Agenet (PF05641, IPR008395, SM00743): Agenet domain
REV (PF00424, IPR000625): REV protein (anti-repression trans-activator protein)
KH_1 (PF00013, IPR004088, SM00322): KH domain
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
32 GID8interactor200LisH (PF08513, IPR013720, SM00667): LisH
CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
33 GSTP1suppressor110.6671.717GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
34 HDAC5protein found in more fusions220.62410.882Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
35 HDGFinteractor70.8100.417PWWP (PF00855, IPR000313, SM00293): PWWP domain
36 HNRNPA0interactor340.58340.890SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus
37 HNRNPA1interactor710.302786.674RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
38 HNRNPCprotein found in more fusions440.388162.312APG6 (PF04111, IPR007243): Autophagy protein Apg6
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2)
39 HNRNPDoncoprotein390.440117.850CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
40 HNRNPFinteractor380.56064.744RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
41 HNRNPH1oncoprotein390.52968.574RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
42 HNRNPH2interactor300.57436.404RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
43 HNRNPKoncoprotein560.382396.417ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
44 HNRNPMinteractor420.50491.383RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
45 HNRNPRinteractor480.473155.771RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
46 HNRNPUL1protein found in more fusions260.43350.712Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Rox3 (PF08633, IPR013942): Rox3 mediator complex subunit
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
47 HPDinteractor100Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
Glyoxalase_3 (PF13468, IPR025870): Glyoxalase-like domain
48 IFIT3interactor50.6670.223TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
49 ITGA4interactor280.58728.970FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
50 ITSN2protein found in more fusions50.6670.800C2 (PF00168, IPR000008, SM00239): C2 domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26
VIR_N (PF15912, IPR031801): Virilizer, N-terminal
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
51 IVNS1ABPprotein found in more fusions140.6416.989BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
52 JAK2oncoprotein50.5002.667FERM_M (PF00373, IPR019748): FERM central domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
53 KHDRBS1protein found in more fusions290.50557.971KH_1 (PF00013, IPR004088, SM00322): KH domain
Qua1 (PF16274, IPR032571): Qua1 domain
Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
54 KHDRBS2interactor160.58112.588KH_1 (PF00013, IPR004088, SM00322): KH domain
Qua1 (PF16274, IPR032571): Qua1 domain
Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
55 KHDRBS3interactor140.43626.059KH_1 (PF00013, IPR004088, SM00322): KH domain
Qua1 (PF16274, IPR032571): Qua1 domain
Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
56 LNX1interactor60.4004.583PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
57 LUZP4interactor100.4724.090Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
58 MAGOHinteractor260.51431.157Mago_nashi (PF02792, IPR004023): Mago nashi protein
59 MAGOHBinteractor30.6670.100Mago_nashi (PF02792, IPR004023): Mago nashi protein
60 MALSU1interactor21.0000RsfS (PF02410, IPR025656): Ribosomal silencing factor during starvation
61 MATR3interactor390.49188.600DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FAM60A (PF15396, IPR026065): Protein Family FAM60A
62 MCM2oncoprotein390.430134.062AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
63 MCM5oncoprotein220.58913.687MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
64 MEPCEinteractor150.7812.636Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3)
Methyltransf_23 (PF13489): Methyltransferase domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7
65 MTERF3interactor50.7001.278mTERF (PF02536, IPR003690, SM00733): mTERF
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
66 NGRNinteractor21.0000Neugrin (PF06413, IPR010487): Neugrin
67 NIF3L1interactor31.0000NIF3 (PF01784, IPR002678): NIF3 (NGG1p interacting factor 3)
68 NUCKS1interactor100FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated
69 NXF1interactor300.44176.778NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
70 OBSL1interactor420.48472.770BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
71 P3H2interactor100TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
YfiO (PF13525): Outer membrane lipoprotein
2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
72 PAIP1interactor41.0000MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
73 PAN2interactor130.50011.887RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
74 PPP1CBinteractor150.34327.869Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
75 PPP1CConcoprotein100.31117.378Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
76 PPP2R1Aoncoprotein170.5447.987TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
77 PRR3interactor70.6194.500zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
78 PSMF1interactor40.6670.500PI31_Prot_C (PF08577, IPR013886): PI31 proteasome regulator
PI31_Prot_N (PF11566, IPR021625): PI31 proteasome regulator N-terminal
79 PTCD1interactor50.7000.526PPR_2 (PF13041, IPR002885): PPR repeat family
PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain
PPR_long (PF17177): Pentacotripeptide-repeat region of PROPR
80 QKIprotein found in more fusions90.5366.135KH_1 (PF00013, IPR004088, SM00322): KH domain
STAR_dimer (PF16544, IPR032377): Homodimerisation region of STAR domain protein
Quaking_NLS (PF16551, IPR032367): Putative nuclear localisation signal of quaking
81 RALYinteractor250.59052.235RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
82 RB1CC1suppressor50.6001.190Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II
DHC (PF09626, IPR018588): Dihaem cytochrome c
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
ATG11 (PF10377, IPR019460): Autophagy-related protein 11
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
Jag_N (PF14804, IPR032782): Jag N-terminus
NPBW (PF15180, IPR013297): Neuropeptides B and W
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
Goodbye (PF17109, IPR031350): fungal STAND N-terminal Goodbye domain
83 RBM14suppressor250.51329.963RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
84 RBM45interactor61.0000RNA_bind (PF08675, IPR014789): RNA binding domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
85 RBMY1A1interactor60.5003.500RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Sulfakinin (PF08257, IPR013259): Sulfakinin family
BMP2K_C (PF15282, IPR028182): BMP-2-inducible protein kinase C-terminus
86 RBMY1Finteractor70.4675.500RBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Sulfakinin (PF08257, IPR013259): Sulfakinin family
87 RNF2interactor270.46843.099zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
88 ROBO3interactor21.0000Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
89 RPL31interactor160.53313.933Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e
90 RPS28interactor120.6522.742Ribosomal_S28e (PF01200, IPR000289): Ribosomal protein S28e
91 RPSAinteractor250.46040.228Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
92 SAFBsuppressor220.41653.079RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAP (PF02037, IPR003034, SM00513): SAP domain
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
93 SAFB2suppressor160.50024.534LicD (PF04991, IPR007074): LicD family
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAP (PF02037, IPR003034, SM00513): SAP domain
DUF4228 (PF14009, IPR025322): Domain of unknown function (DUF4228)
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
94 SF3A1interactor290.65320.064TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Surp (PF01805, IPR000061, SM00648): Surp module
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
95 SF3A2interactor240.59134.801Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32
PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
zf-met (PF12874): Zinc-finger of C2H2 type
ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix
SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
96 SF3B1oncoprotein350.51352.567Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
97 SF3B2interactor240.55820.995DUF382 (PF04037, IPR007180): Domain of unknown function (DUF382)
PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region
PSP (PF04046, IPR006568, SM00581): PSP
SAP (PF02037, IPR003034, SM00513): SAP domain
Usp (PF00582, IPR006016): Universal stress protein family
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
Vma12 (PF11712, IPR021013): Endoplasmic reticulum-based factor for assembly of V-ATPase
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
98 SF3B3interactor310.56649.921CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
99 SIRT7interactor270.30587.242DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
100 SNW1protein found in more fusions370.58173.230SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
101 SOCS3suppressor21.0000SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
102 SORBS3interactor50.6670.287Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
103 SPICE1interactor40.5001.917SPICE (PF15678, IPR031387): Centriole duplication and mitotic chromosome congression
ANXA2R (PF15721, IPR031449): Annexin-2 receptor
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
104 SREK1protein found in more fusions130.5006.671Ureide_permease (PF07168, IPR009834): Ureide permease
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
105 SRPK2oncoprotein300.47383.623DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
106 SRPK3interactor90.6672.200Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
Pkinase (PF00069, IPR000719): Protein kinase domain
107 SRRM1interactor260.56327.782DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP)
Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen
MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family)
PWI (PF01480, IPR002483, SM00311): PWI domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
108 SRRM2interactor350.53681.609cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Pap_E4 (PF02711, IPR003861): E4 protein
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
109 STAT5Asuppressor60.4004.439SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
110 STAU1protein found in more fusions330.51463.353dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
111 TRA2Binteractor190.46234.348RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
112 TRUB2interactor50.8330.500TruB_N (PF01509, IPR002501): TruB family pseudouridylate synthase (N terminal domain)
TruB_C_2 (PF16198, IPR032819): tRNA pseudouridylate synthase B C-terminal domain
113 U2AF2protein found in more fusions420.53285.585RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
114 USP45interactor40.5000.622HNH (PF01844, IPR002711): HNH endonuclease
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
LELP1 (PF15042, IPR026076): Late cornified envelope-like proline-rich protein 1
115 VCAM1interactor250.54027.165C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
116 XRN1interactor40.8330.105XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus
117 YARS2interactor50.8001.167S4 (PF01479, IPR002942, SM00363): S4 domain
tRNA-synt_1b (PF00579, IPR002305): tRNA synthetases class I (W and Y)
118 YTHDC1interactor120.57612.031DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
YTH (PF04146, IPR007275): YT521-B-like domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
TFB6 (PF17110, IPR031349): Subunit 11 of the general transcription factor TFIIH
119 ZC3H18interactor160.45018.433FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
Miga (PF10265, IPR019392): Mitoguardin
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
LRR19-TM (PF15176): Leucine-rich repeat family 19 TM domain
120 ZNF490interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger

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List of missing interactors

# Name Type Domains (Pfam, InterPro, SMART): description Fusion(s)
1 APOBEC3CinteractorAPOBEC_N (PF08210, IPR013158): APOBEC-like N-terminal domain
2 CIRBPoncoproteinRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
3 CSNK2A1oncoproteinPkinase (PF00069, IPR000719): Protein kinase domain
4 ELAVL2interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
5 FOXS1interactorForkhead (PF00250, IPR001766, SM00339): Forkhead domain
6 IL7Rinteractorfn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
7 MCATinteractorAcyl_transf_1 (PF00698, IPR014043): Acyl transferase domain
8 NABP1interactortRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
9 NCOA5suppressorMacoilin (PF09726, IPR019130): Transmembrane protein
10 NFE2L2oncoproteinbZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
11 NTRK1oncoproteinI-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
12 RAC1oncoproteinRas (PF00071, IPR001806, SM00173): Ras family
13 RBM3interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
14 RBM7interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
15 RBM8AinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
16 RBMXparental proteinRBM1CTR (PF08081, IPR012604): RBM1CTR (NUC064) family
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
17 RRM2interactorRibonuc_red_sm (PF00268, IPR000358): Ribonucleotide reductase, small chain
18 SCARNA22interactorNA
19 SF3B4interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
20 SF3B6interactorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
21 SNRPAinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
22 TARDBPinteractorRRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
23 WWOXsuppressoradh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain

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